[Hub]/) : Traits : Whole body fat-free mass : ← →

chr4:85,698,680-88,430,396

Best TWAS P=1.13e-10 · Best GWAS P=1.18e-10 conditioned to 0.522

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Colon Sigmoid	MAPK10	0.25	0.11	lasso	8	0.07	1.6e-03	6.2	-6.5	1.1e-10	-0.89	0.02	0.96	TRUE
6	GTEx	Artery Tibial	RP13-514E23.2	0.22	0.16	enet	10	0.18	1.2e-13	-5.6	-5.7	1.5e-08	-0.07	0.18	0.82	TRUE
9	GTEx	Thyroid	PTPN13	0.41	0.31	lasso	6	0.30	3.2e-23	6.4	6.3	3.4e-10	0.99	0.01	0.99	FALSE
2	GTEx	Artery Aorta	MAPK10	0.15	0.17	enet	16	0.17	1.4e-09	6.2	-6.1	1.3e-09	-0.96	0.01	0.99	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	PTPN13	0.09	0.03	blup	409	0.07	4.7e-09	5.6	-6.0	2.1e-09	-0.53	0.54	0.46	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PTPN13	0.13	0.18	bslmm	418	0.18	6.8e-22	5.5	-5.9	3.9e-09	-0.53	0.56	0.44	FALSE
4	GTEx	Artery Aorta	RP13-514E23.2	0.26	0.09	lasso	6	0.10	2.2e-06	-5.6	-5.6	2.4e-08	-0.08	0.21	0.79	FALSE
5	GTEx	Artery Tibial	ARHGAP24	0.26	0.19	enet	14	0.21	2.7e-16	-5.6	-5.4	5.4e-08	-0.05	0.16	0.84	FALSE
3	GTEx	Artery Aorta	ARHGAP24	0.24	0.13	enet	8	0.14	2.2e-08	-4.2	-5.3	8.8e-08	-0.10	0.50	0.50	FALSE
7	GTEx	Brain Caudate basal ganglia	PTPN13	0.26	0.16	enet	17	0.11	4.6e-04	5.6	-5.3	1.1e-07	-0.40	0.24	0.45	FALSE