TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
←
→
chr4:110,042,428-111,439,602
Best TWAS P=2.18e-08 · Best GWAS P=1.49e-08 conditioned to 1
110M
110.2M
110.4M
110.6M
110.8M
111M
111.2M
111.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
GAR1
0.04
0.06
lasso
2
0.06
8.1e-07
5.6
5.6
2.2e-08
0.99
0.00
1.00
TRUE
5
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
GAR1
0.10
0.09
lasso
2
0.07
6.8e-04
5.7
-5.6
2.6e-08
-0.99
0.00
0.96
FALSE
1
GTEx
Brain Frontal Cortex BA9
GAR1
0.22
0.08
lasso
3
0.04
2.9e-02
5.4
-5.5
3.1e-08
-0.94
0.01
0.85
FALSE
3
ROSMAP
Brain Pre-frontal Cortex
GAR1
0.18
0.24
enet
17
0.24
2.2e-30
5.7
-5.4
7.2e-08
-0.98
0.00
1.00
FALSE
2
GTEx
Esophagus Mucosa
GAR1
0.17
0.16
lasso
3
0.15
1.9e-10
5.4
5.3
1.4e-07
0.99
0.01
0.99
FALSE