[Hub]/) : Traits : Whole body fat-free mass : ← →

chr4:121,982,122-124,538,705

Best TWAS P=1.51e-18 · Best GWAS P=1.34e-15 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCNA2	0.03	0.01	blup	34	0.02	1.5e-03	-7.40	8.8	1.5e-18	0.02	0.00	0.97	TRUE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FGF2	0.06	0.04	blup	65	0.05	4.4e-06	6.90	6.5	7.8e-11	0.85	0.01	0.98	TRUE
5	GTEx	Artery Tibial	FGF2	0.18	0.05	lasso	3	0.02	1.3e-02	6.20	6.4	1.7e-10	0.36	0.08	0.11	TRUE
9	GTEx	Breast Mammary Tissue	NUDT6	0.25	0.10	lasso	3	0.08	4.2e-05	6.23	6.2	4.2e-10	0.83	0.10	0.86	TRUE
10	GTEx	Breast Mammary Tissue (Male)	NUDT6	0.29	0.00	lasso	6	0.00	3.5e-01	5.96	6.1	1.1e-09	0.74	0.04	0.41	TRUE
14	GTEx	Colon Transverse	BBS12	0.12	0.05	enet	29	0.12	3.2e-06	0.66	6.0	1.4e-09	0.48	0.04	0.57	TRUE
19	GTEx	Skin Sun Exposed Lower leg	NUDT6	0.11	0.08	lasso	3	0.08	6.2e-07	5.96	6.0	1.8e-09	0.70	0.94	0.02	TRUE
18	GTEx	Skin Not Sun Exposed Suprapubic	NUDT6	0.07	0.02	lasso	6	0.03	1.5e-02	4.81	5.8	6.8e-09	0.71	0.19	0.60	TRUE
11	GTEx	Breast Mammary Tissue (Female)	NUDT6	0.30	-0.01	enet	30	0.00	2.6e-01	6.43	5.7	1.4e-08	0.62	0.03	0.32	TRUE
22	ROSMAP	Brain Pre-frontal Cortex	NUDT6	0.04	0.04	enet	9	0.03	2.0e-04	6.12	5.5	3.2e-08	0.64	0.63	0.15	TRUE
13	GTEx	Cells Transformed fibroblasts	BBS7	0.16	0.09	lasso	7	0.16	2.9e-12	-7.49	-8.0	9.1e-16	-0.03	0.00	1.00	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	EXOSC9	0.04	0.05	lasso	2	0.04	7.1e-05	7.12	8.0	1.7e-15	0.03	0.02	0.96	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	EXOSC9	0.03	0.04	enet	9	0.04	2.8e-08	7.12	7.9	3.8e-15	0.02	0.08	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	BBS7	0.19	0.21	bslmm	423	0.23	1.8e-27	-7.43	-7.7	1.1e-14	-0.01	0.00	1.00	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EXOSC9	0.03	0.02	lasso	2	0.02	1.0e-03	7.05	7.5	4.6e-14	0.01	0.05	0.56	FALSE
20	GTEx	Testis	EXOSC9	0.17	0.07	lasso	8	0.10	2.5e-05	-5.73	7.5	5.7e-14	0.04	0.02	0.98	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	EXOSC9	0.29	0.17	lasso	7	0.16	6.6e-06	6.89	7.5	7.1e-14	0.01	0.12	0.87	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	BBS7	0.04	0.04	lasso	2	0.03	6.1e-04	-7.43	-7.4	1.0e-13	-0.03	0.00	1.00	FALSE
23	YFS	Blood	EXOSC9	0.06	0.09	bslmm	401	0.09	7.0e-28	6.97	7.4	1.8e-13	0.00	0.12	0.88	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	BBS7	0.05	0.00	blup	47	0.02	1.9e-02	7.15	-7.2	5.0e-13	-0.03	0.02	0.24	FALSE
15	GTEx	Muscle Skeletal	NUDT6	0.15	0.12	lasso	3	0.11	1.1e-10	6.17	6.2	4.9e-10	0.74	0.99	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	NUDT6	0.04	0.04	lasso	3	0.02	6.5e-04	6.17	6.2	5.6e-10	0.74	0.72	0.03	FALSE
6	GTEx	Artery Tibial	NUDT6	0.08	0.08	lasso	5	0.05	5.6e-05	6.03	6.2	7.3e-10	0.73	0.65	0.08	FALSE
16	GTEx	Muscle Skeletal	RP11-170N16.3	0.07	0.07	lasso	3	0.06	8.8e-07	5.30	6.1	1.1e-09	0.74	0.23	0.76	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUDT6	0.02	0.02	lasso	4	0.01	5.4e-03	6.03	6.0	1.8e-09	0.72	0.13	0.14	FALSE
8	GTEx	Brain Cerebellum	BBS7	0.20	-0.01	enet	24	0.01	2.2e-01	-5.65	-5.9	3.1e-09	-0.03	0.07	0.73	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	EXOSC9	0.05	0.02	lasso	7	0.02	5.3e-04	5.17	5.8	5.1e-09	-0.03	0.21	0.65	FALSE
17	GTEx	Nerve Tibial	NUDT6	0.11	0.08	lasso	3	0.05	2.1e-04	5.76	5.8	8.2e-09	0.69	0.80	0.02	FALSE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUDT6	0.10	0.07	lasso	6	0.07	1.0e-07	6.03	5.7	1.1e-08	0.71	0.97	0.03	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TMEM155	0.06	0.05	lasso	3	0.02	5.5e-04	-6.02	-5.5	3.0e-08	-0.05	0.13	0.81	FALSE
28	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BBS7	0.04	0.02	blup	47	0.03	1.3e-04	-5.71	-5.5	3.8e-08	-0.03	0.06	0.90	FALSE
26	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CCNA2	0.11	-0.01	enet	14	0.02	4.4e-02	0.64	5.5	5.1e-08	0.09	0.00	0.26	FALSE
4	GTEx	Adipose Subcutaneous	EXOSC9	0.07	0.00	lasso	2	0.00	4.5e-01	-5.73	5.4	6.2e-08	0.04	0.05	0.32	FALSE
7	GTEx	Brain Cerebellar Hemisphere	BBS7	0.27	0.05	lasso	3	0.08	4.7e-03	-5.71	-5.3	1.1e-07	-0.01	0.08	0.33	FALSE