TWAS hub - RGS17

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0690	0.0260	2.6e-03	0.006	0.024	0.030	0.028	0.024	4.9e-02	5.1e-04	1.2e-04	1.9e-04	5.6e-04
2	GTEx	Adipose Subcutaneous	0.0970	0.0320	4.1e-04	0.043	NA	0.051	NA	0.059	1.8e-04	NA	5.3e-05	NA	1.3e-05
3	GTEx	Cells Transformed fibroblasts	0.1350	0.0500	1.2e-03	0.015	NA	0.002	NA	0.015	2.5e-02	NA	2.2e-01	NA	2.6e-02
4	GTEx	Esophagus Mucosa	0.2160	0.0500	5.5e-08	0.147	NA	0.148	NA	0.178	4.8e-10	NA	4.1e-10	NA	5.5e-12
5	GTEx	Thyroid	0.2540	0.0610	4.3e-06	0.042	NA	0.086	NA	0.089	3.3e-04	NA	3.9e-07	NA	2.5e-07
6	YFS	Blood	0.0958	0.0175	0.0e+00	0.107	0.072	0.106	0.097	0.100	3.1e-33	1.4e-22	6.3e-33	5.0e-30	6.2e-31
7	TCGA	Breast Invasive Carcinoma	0.0187	0.0093	7.1e-04	0.023	0.014	0.017	NA	0.014	1.1e-05	6.6e-04	1.8e-04	NA	5.0e-04
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0430	0.0184	1.6e-05	0.039	0.053	0.039	NA	0.045	3.3e-05	1.2e-06	3.1e-05	NA	8.4e-06
9	TCGA	Prostate Adenocarcinoma	0.3362	0.0633	0.0e+00	0.293	0.270	0.270	NA	0.294	5.8e-31	3.0e-28	3.3e-28	NA	5.7e-31
10	TCGA	Rectum Adenocarcinoma	0.1800	0.0820	4.4e-03	-0.009	0.000	-0.007	NA	-0.010	5.8e-01	3.2e-01	5.0e-01	NA	6.3e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Fasting Glucose	9.2	11.0	23.9	-2.5	-3.5	-3.4	-4.9	2.6	1.7	-2.9	-4.1	-4.5	-1.0
Tinnitus: Yes, now most or all of the time	7.8	9.1	16.1	-1.7	-3.9	-2.4	-2.0	2.0	3.2	-3.9	-3.2	-2.7	-4.0
Falls in the last year	6.0	8.1	17.0	2.9	3.0	2.1	2.0	-4.1	-2.5	3.2	2.7	2.4	2.9
Tense / ‘highly strung’	5.7	9.4	17.2	2.5	3.2	3.2	3.7	-2.6	-1.7	3.1	3.5	4.1	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.5	6.5	10.4	-3.0	-2.7	-1.4	-2.1	3.2	2.5	-2.8	-3.0	-2.6	-1.7
Diabetes diagnosed by doctor	5.1	8.4	15.1	-2.7	-3.0	-2.7	-3.6	2.4	2.1	-2.8	-3.7	-3.9	-0.9
Waist circumference	5.0	18.2	26.3	-3.0	-4.9	-3.8	-3.3	4.7	4.5	-5.1	-4.6	-4.2	-4.1
Bipolar Disorder (2011)	4.7	4.5	10.2	3.2	1.4	2.8	2.0	0.0	-1.4	1.9	2.3	1.8	2.7
BMI	4.7	27.4	40.1	-5.1	-5.4	-4.9	-5.1	5.9	4.1	-5.5	-6.3	-5.8	-3.7
Chronic bronchitis/emphysema (father)	4.7	5.5	9.9	-0.6	-3.1	-1.0	-1.9	3.2	3.0	-2.9	-2.1	-2.7	-1.4
Risk taking	4.6	6.7	14.2	0.8	2.5	3.2	3.8	-2.2	-1.5	2.1	2.5	3.3	2.7
Alcohol usually taken with meals	4.5	7.3	13.1	-2.8	-3.0	-2.1	-2.6	2.3	2.4	-2.8	-3.6	-2.7	-2.3
Severe depression (siblings)	4.4	4.9	8.4	1.5	2.1	2.2	2.9	-2.4	-1.4	2.0	2.7	2.4	2.0
Arm fat mass (left)	4.3	17.8	23.0	-3.4	-4.6	-4.0	-3.8	4.4	3.7	-4.8	-4.7	-4.4	-4.2
Supplements: Glucosamine	4.2	5.4	9.0	0.0	-2.9	-1.8	-2.8	1.8	1.7	-2.4	-2.3	-2.9	-3.0
Pack years of smoking	4.1	6.0	9.9	-2.5	-2.6	-0.9	-2.6	3.2	2.1	-2.7	-2.9	-2.7	-1.5
Worry (Nagel 2018)	4.0	8.4	13.9	3.2	3.0	2.7	3.4	-2.7	-1.3	2.8	3.5	3.7	1.7
Eye problems/disorders: Diabetes related eye disease	3.7	4.1	7.8	-1.1	-2.8	-1.6	-1.3	2.4	2.3	-2.3	-2.1	-2.5	-0.4
Body mass index (BMI)	3.7	15.8	21.2	-3.6	-4.0	-3.5	-4.2	4.5	2.9	-4.0	-4.6	-4.5	-3.7
Arm fat mass (right)	3.7	15.1	19.6	-3.4	-4.2	-3.6	-3.5	4.0	3.5	-4.4	-4.4	-4.0	-3.6
Worrier / anxious feelings	3.6	6.8	12.3	2.9	2.7	2.2	3.3	-1.8	-1.4	2.6	3.2	3.5	1.7
Pack years adult smoking proportion	3.5	5.3	8.7	-2.5	-2.5	-0.7	-2.3	2.9	2.1	-2.6	-2.9	-2.5	-0.7
Diabetes (self-reported)	3.5	5.4	10.4	-2.1	-2.5	-2.1	-3.1	1.4	1.5	-2.2	-3.1	-3.2	-0.6
Supplements: Vitamin C	3.4	4.0	6.2	1.1	2.3	2.3	1.6	-2.1	-2.1	2.5	2.2	1.9	1.4
Maternal smoking around birth	3.3	4.7	10.3	-3.2	-1.9	-0.2	-2.7	2.4	0.4	-1.4	-3.0	-3.1	0.2
Diabetes (father)	3.2	3.9	7.4	-1.6	-2.3	-2.7	-1.0	1.3	2.5	-2.7	-1.7	-1.5	-1.7
Impedance of leg (right)	3.2	15.6	23.8	3.4	4.3	3.7	4.1	-3.0	-3.4	4.6	4.9	4.0	3.7
Trunk fat mass	3.2	13.8	19.0	-3.2	-4.1	-3.1	-3.1	4.2	3.4	-4.4	-4.1	-3.8	-3.5
Whole body fat mass	3.2	13.2	17.6	-3.0	-4.0	-3.1	-3.0	4.2	3.3	-4.2	-3.9	-3.7	-3.7
Arm fat percentage (left)	3.2	12.6	18.6	-3.3	-3.5	-2.7	-4.0	4.0	2.2	-3.4	-4.1	-4.3	-3.3
Ever taken oral contraceptive pill	3.2	3.5	5.4	-1.1	-2.2	-2.2	-1.3	1.6	2.2	-2.3	-2.3	-1.9	-0.9
HDL Cholesterol	3.1	5.1	11.2	1.0	2.6	3.4	2.5	-0.9	-2.2	2.5	2.3	2.7	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	3.1	4.7	8.1	1.7	2.3	2.6	2.7	-0.6	-1.2	2.1	2.9	2.4	2.2
Migraine (self-reported)	3.1	3.8	8.9	1.5	1.8	1.6	2.8	-2.4	-0.2	1.1	2.5	3.0	-0.2
Illnesses of siblings: Diabetes	3.1	3.9	5.7	-2.3	-2.1	0.3	-1.6	2.1	2.0	-2.2	-2.4	-2.2	-1.5
Neuroticism (2016)	2.9	4.2	7.8	0.6	2.7	2.2	0.7	-1.6	-2.6	2.8	1.7	1.3	2.8
Type 2 Diabetes (T2D) (2018)	2.9	5.4	10.1	-1.4	-2.6	-2.6	-2.9	1.6	2.0	-2.2	-3.1	-3.2	-0.3
Other serious medical condition/disability diagnosed by doctor	2.9	3.7	6.1	1.8	2.0	1.6	2.4	-2.0	-1.4	1.9	2.3	2.5	0.9
Weight	2.9	14.1	23.9	-2.6	-4.5	-3.7	-2.2	3.8	4.3	-4.9	-4.1	-3.1	-3.4
Cholesterol lowering medication	2.9	4.3	7.2	-1.7	-2.5	-1.2	-2.6	1.1	1.8	-2.6	-2.7	-2.5	-1.0
Arm fat percentage (right)	2.8	10.9	16.4	-3.1	-3.2	-2.5	-3.9	3.7	2.2	-3.2	-4.0	-4.0	-2.6
Alcohol drinker status: Never	2.8	3.4	9.4	1.6	1.9	0.3	1.7	-3.1	-1.4	1.9	1.9	1.9	1.6
Leg fat mass (left)	2.8	10.8	14.8	-2.8	-3.5	-3.0	-2.8	3.9	2.9	-3.6	-3.6	-3.5	-3.1
Bipolar Disorder or Schizophrenia	2.7	6.6	12.6	2.8	2.6	2.0	2.4	-2.0	-2.2	2.7	2.8	2.4	3.5
Chronotype (morning person)	2.7	6.2	10.1	3.0	2.5	0.9	1.9	-2.5	-2.1	2.7	3.2	2.6	2.7
Trunk fat percentage	2.7	10.7	14.5	-3.1	-3.3	-2.4	-3.4	3.8	2.3	-3.4	-3.6	-3.8	-3.2
Arm predicted mass (right)	2.7	13.8	28.0	-2.5	-4.7	-3.9	-1.1	3.0	5.0	-5.3	-3.7	-2.2	-3.6
Long-standing illness, disability or infirmity	2.7	4.2	9.0	1.1	3.0	2.1	0.8	-1.6	-2.7	3.0	2.3	1.7	0.5
Hearing aid user	2.7	3.1	4.3	1.4	1.9	1.9	1.9	-2.1	-1.4	2.0	1.9	1.8	0.8
Father’s age at death	2.6	3.5	12.5	-2.1	-1.3	-1.5	-2.3	0.3	0.6	-1.3	-1.2	-2.2	-3.5
Birth weight	2.6	5.7	14.0	3.4	1.1	0.1	3.7	-2.7	0.4	0.5	3.1	3.7	0.2
Arm fat-free mass (right)	2.6	13.4	26.7	-2.3	-4.6	-3.8	-0.9	3.1	5.0	-5.2	-3.4	-2.1	-3.9
Arm fat-free mass (left)	2.6	13.1	27.8	-2.1	-4.7	-3.9	-0.9	2.7	5.1	-5.3	-3.5	-1.9	-3.3
Arm predicted mass (left)	2.6	13.0	26.8	-2.5	-4.6	-4.0	-1.1	2.7	5.0	-5.2	-3.8	-2.2	-2.8
Frequency of depressed mood in last 2 weeks	2.5	3.5	5.9	1.7	1.4	2.2	2.2	-2.4	-1.1	1.5	1.9	1.9	2.0
Body fat percentage	2.5	9.7	15.1	-2.9	-3.0	-2.2	-3.4	3.9	2.0	-3.0	-3.5	-3.8	-3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.5	3.3	6.8	1.3	2.3	2.5	1.2	0.3	-1.8	2.6	2.3	1.2	1.2
Leg fat mass (right)	2.5	9.8	15.3	-2.8	-3.3	-2.8	-2.6	3.9	2.8	-3.4	-3.4	-3.3	-2.9
Illnesses of father: None of the above (group 1)	2.5	3.0	5.7	1.1	2.1	0.8	1.4	-2.4	-1.6	2.0	1.7	2.1	1.6
Impedance of leg (left)	2.4	11.7	17.7	3.3	3.6	3.1	3.5	-2.9	-3.0	3.9	4.2	3.4	3.2
Leg predicted mass (right)	2.4	12.7	26.5	-2.2	-4.6	-4.0	-1.4	2.4	4.8	-5.1	-4.1	-2.3	-2.5
Basal metabolic rate	2.4	13.0	27.4	-2.2	-4.7	-4.0	-1.0	2.8	5.0	-5.2	-3.8	-2.1	-2.7
Schizophrenia (2018)	2.3	4.8	8.0	2.6	2.4	1.8	1.7	-1.6	-2.1	2.7	2.8	1.7	2.2
Body Mass Index (BMI) (2010)	2.3	3.2	8.0	-1.1	-1.4	-2.1	-2.8	0.9	0.6	-1.3	-1.9	-2.3	-2.1
Leg fat-free mass (left)	2.3	11.9	24.4	-2.4	-4.3	-3.8	-1.3	2.7	4.6	-4.9	-3.9	-2.2	-2.4
Leg predicted mass (left)	2.3	11.9	24.8	-2.3	-4.4	-3.8	-1.2	2.6	4.7	-5.0	-3.8	-2.2	-2.4
Hip circumference	2.3	9.9	18.2	-2.7	-3.7	-2.6	-1.7	2.9	3.6	-4.3	-3.6	-2.2	-3.4
Number of live births	2.3	3.3	6.2	-1.2	-1.9	-0.2	-2.1	2.3	1.1	-1.7	-1.6	-2.3	-2.5
Leg fat-free mass (right)	2.3	12.5	26.0	-2.2	-4.5	-4.0	-1.4	2.4	4.7	-5.1	-4.0	-2.2	-2.5
Whole body water mass	2.3	12.9	27.7	-2.1	-4.7	-4.0	-0.8	2.5	5.2	-5.3	-3.8	-2.0	-2.6
Wears glasses or contact lenses	2.3	2.7	5.6	0.6	2.4	1.4	1.3	-1.1	-2.2	2.2	1.8	2.0	-0.0
Illnesses of father: High blood pressure	2.3	2.9	4.0	1.9	1.8	1.0	1.6	-1.6	-1.4	1.8	1.9	1.7	2.0
Basal cell carcinoma (self-reported)	2.3	2.7	5.5	-1.9	-1.8	-1.1	-2.3	0.8	0.9	-1.7	-1.9	-2.2	-0.4
Schizophrenia (2014)	2.2	4.8	7.6	2.3	2.4	2.3	1.6	-1.4	-2.5	2.8	2.7	1.5	2.3
Impedance of arm (right)	2.2	10.0	16.0	2.8	3.3	3.4	2.5	-3.1	-2.8	3.6	3.2	2.7	4.0
Breastfed as a baby	2.2	2.8	6.9	2.5	1.2	1.3	1.4	-2.6	-1.0	1.3	1.8	1.8	0.1
Pulse rate, automated reading	2.2	7.2	14.4	2.6	2.2	1.4	3.8	-2.2	-1.3	1.9	3.5	3.6	2.9
Whole body fat-free mass	2.2	12.4	27.2	-2.0	-4.6	-3.9	-0.6	2.5	5.2	-5.2	-3.7	-1.8	-2.6
Mineral and other dietary supplements	2.2	3.0	5.8	-1.0	2.0	1.6	2.4	0.1	-1.2	1.7	1.7	1.8	2.4
Fractured/broken bones in last 5 years	2.2	2.8	5.4	2.3	1.5	1.5	1.5	-2.1	-1.0	1.4	1.6	2.1	1.4
Age at First Birth	2.1	3.0	7.6	2.8	0.9	-0.9	2.1	-2.5	0.2	0.7	2.1	2.1	0.8
Hand grip strength (right)	2.1	5.8	10.9	-1.9	-3.2	-2.7	-1.2	1.6	2.6	-3.3	-3.1	-2.3	-0.4
Forced vital capacity (FVC), Best measure	2.1	7.9	19.0	3.2	1.0	1.1	4.4	-4.0	0.2	0.8	2.0	3.8	3.5
Commuting to job workplace: Car/motor vehicle	2.1	2.4	4.6	-0.9	-1.6	-1.1	-1.6	2.0	1.1	-1.5	-2.1	-2.0	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.3	4.2	-1.3	-1.6	-1.4	-1.4	1.7	1.1	-1.5	-0.9	-1.8	-2.0
Smoking status: Current	2.1	3.3	6.2	-1.6	-2.4	0.1	-1.6	2.2	1.6	-1.9	-1.8	-2.5	-1.2
Ever smoked	2.1	3.6	5.9	-1.7	-2.2	-0.4	-1.5	2.2	2.0	-2.3	-1.7	-1.9	-2.4
Leg fat percentage (left)	2.1	7.5	13.9	-2.8	-2.4	-1.7	-3.2	3.7	1.5	-2.3	-2.9	-3.4	-2.5
Reaction Time	2.0	3.7	7.4	1.6	2.3	1.0	2.3	-0.4	-1.5	2.3	1.9	2.1	2.7
Hand grip strength (left)	2.0	5.3	10.4	-2.4	-3.0	-1.8	-1.2	2.0	2.4	-2.9	-3.2	-2.3	-0.0
Medication: Metformin	2.0	2.9	5.0	-1.1	-2.0	-1.9	-1.8	1.0	1.8	-1.9	-2.2	-2.0	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.4	3.7	0.2	1.9	1.7	1.6	-1.5	-1.6	1.5	1.8	1.7	1.3
Osteoporosis (self-reported)	2.0	2.5	6.2	2.5	1.8	1.0	1.0	-0.4	-1.5	2.0	2.3	1.3	0.8
Impedance of whole body	2.0	10.1	14.0	2.8	3.4	3.2	2.8	-2.8	-3.1	3.7	3.7	2.8	3.3
Systolic Blood Pressure	1.9	9.7	28.0	3.9	2.9	0.8	3.1	-5.3	-1.4	2.5	2.9	3.9	1.7
Supplements: Zinc	1.9	2.0	5.3	1.8	1.3	1.1	1.1	-1.2	-1.1	1.4	1.2	1.3	2.3
Current tobacco smoking	1.9	3.1	5.7	-1.9	-2.2	0.3	-1.6	2.2	1.4	-1.8	-1.6	-2.4	-1.5
Pulse rate	1.9	3.2	5.8	2.3	1.2	-0.6	2.4	-1.9	-0.5	0.9	2.3	2.4	1.9
Suffer from ‘nerves’	1.9	2.9	5.0	2.2	1.6	1.4	2.2	-1.6	-0.2	1.2	2.2	2.2	1.1
Unable to work because of sickness or disability	1.9	2.5	5.0	1.0	1.6	2.2	1.6	-2.0	-1.0	1.4	1.4	1.6	1.5
Triglycerides	1.8	3.0	4.4	-0.5	-2.0	-2.1	-2.0	1.7	1.5	-1.9	-2.1	-2.0	-0.0
Trunk fat-free mass	1.8	10.4	25.2	-1.5	-4.3	-3.6	-0.1	2.1	5.0	-4.9	-3.1	-1.3	-2.3
Trunk predicted mass	1.8	10.1	24.6	-1.5	-4.2	-3.5	-0.1	2.1	5.0	-4.8	-3.1	-1.3	-2.3
Commuting to job workplace: Cycle	1.8	2.2	8.0	-0.4	1.2	2.1	1.4	-2.8	-0.7	0.9	0.9	1.7	1.2
HbA1C	1.7	1.9	4.1	-0.5	-1.9	-1.7	-0.9	0.2	1.6	-2.0	-1.0	-1.0	-1.8
Smoking Status	1.7	4.0	8.8	-0.5	-2.6	0.1	-2.1	3.0	1.5	-2.1	-2.0	-2.8	-1.2
Qualifications: CSEs or equivalent	1.7	2.3	6.6	0.7	-1.6	-2.6	-0.5	1.5	1.9	-1.8	-1.7	-0.8	0.9
Mean time to correctly identify matches	1.7	3.2	7.2	1.4	2.6	1.0	1.2	-0.6	-2.1	2.7	1.9	1.4	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.1	12.5	2.8	0.2	0.2	3.5	-3.2	0.9	0.0	1.0	3.0	3.0
Impedance of arm (left)	1.6	7.2	9.9	2.5	2.8	2.9	2.2	-2.6	-2.7	3.1	2.9	2.3	2.7
Leg fat percentage (right)	1.6	5.7	14.0	-2.5	-1.9	-1.3	-2.7	3.7	1.1	-1.8	-2.4	-3.0	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	4.2	0.6	1.1	-0.1	-1.4	-1.7	-1.9	1.7	-0.1	-1.1	2.0
Eye problems/disorders: None of the above	1.6	1.8	5.6	0.5	1.7	0.8	2.1	-0.2	-0.9	1.3	1.3	2.4	0.4
Alcohol intake versus 10 years previously	1.5	2.2	4.2	1.5	1.6	1.8	0.9	-1.6	-1.2	1.6	2.0	1.3	1.1
Medication for pain relief, constipation, heartburn	1.5	2.6	8.0	-1.7	-1.1	-2.8	-1.7	0.7	1.0	-1.6	-1.7	-1.1	-1.5
Bipolar Disorder (2018)	1.4	2.2	8.5	1.2	1.3	1.0	1.7	-1.2	-0.8	1.0	0.9	1.7	2.9
Average weekly spirits intake	1.4	1.8	4.0	-1.9	-0.8	-1.2	-2.0	1.2	0.2	-0.8	-1.7	-1.6	-0.7
Diabetes (mother)	1.4	1.8	3.5	-1.4	-1.8	-0.4	-0.6	1.1	1.7	-1.9	-1.5	-1.1	-1.1
Nervous feelings	1.4	2.6	5.5	2.3	1.5	0.8	2.0	-1.5	-0.4	1.2	1.9	2.3	0.8
Forced vital capacity (FVC)	1.4	5.2	14.9	2.1	0.3	1.1	3.9	-3.2	0.9	0.1	1.3	3.1	3.1
Time employed in main current job	1.4	1.7	4.6	0.2	-1.3	-2.1	-0.6	-0.3	1.9	-1.7	-1.0	-0.6	-1.5
Wheeze or whistling in the chest in last year	1.4	2.4	7.2	-2.7	-1.3	-0.6	-1.9	1.7	0.6	-1.3	-1.5	-2.1	-0.3
Average weekly fortified wine intake	1.3	1.6	5.1	0.4	1.5	1.1	1.6	-1.3	-0.4	0.8	1.1	2.2	0.8
Comparative body size at age 10	1.3	3.6	6.4	-2.0	-1.6	-1.3	-2.0	2.5	1.1	-1.6	-2.0	-2.1	-2.2
Knee pain experienced in last month	1.3	2.1	6.4	-0.3	-1.2	-1.4	-2.5	0.4	0.4	-0.9	-2.1	-2.3	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	4.7	0.3	1.1	1.1	-0.7	-0.0	-1.9	1.7	0.1	-0.6	2.2
Heart attack/myocardial infarction (self-reported)	1.3	1.6	4.1	1.2	0.9	0.9	1.8	-2.0	-0.2	0.7	1.3	1.5	1.3
Blood Platelet Count	1.2	13.8	18.9	3.8	4.0	3.1	3.3	-4.3	-3.3	3.8	4.0	4.2	3.0
Waist Hip Ratio (WHR)	1.2	5.2	9.7	0.5	-2.9	-3.1	-1.4	2.2	3.0	-2.7	-1.1	-2.3	-2.2
Lung FVC	1.2	6.2	12.4	2.2	1.5	2.3	3.3	-3.5	-0.6	1.5	2.5	3.1	2.7
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	4.7	-0.5	1.0	0.6	-2.2	1.3	-1.8	1.4	-0.4	-1.0	-0.3
Hair/balding pattern: Pattern 2	1.2	1.5	4.0	-0.7	1.4	2.0	0.6	-1.5	-1.1	1.4	0.5	1.0	1.2
Medication: Paracetamol	1.2	2.0	8.1	1.3	0.7	1.8	1.6	-1.1	0.1	0.8	0.4	1.1	2.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	12.1	1.3	0.9	0.5	1.6	-3.5	-0.4	1.0	1.2	1.4	1.6
Vitamin and mineral supplements	1.1	1.5	10.4	-3.2	-0.2	-0.6	-0.5	1.2	0.5	-0.6	-0.8	-0.5	-1.1
Taking other prescription medications	1.1	1.6	4.3	0.2	2.1	1.4	0.1	-0.6	-1.7	2.0	1.4	1.0	-0.1
Multivitamins +/- minerals	1.1	1.4	9.3	3.0	-0.5	0.8	0.4	-1.6	-0.1	-0.1	0.2	0.3	1.0
Past tobacco smoking	1.1	2.1	3.8	0.6	1.8	0.6	1.0	-2.0	-1.7	1.9	1.2	1.3	1.6
Hearing difficulty/problems with background noise	1.1	1.7	5.2	-1.3	-1.0	0.2	-1.1	2.1	0.4	-0.9	-0.9	-1.4	-2.3
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	10.3	2.0	-0.1	0.3	3.2	-2.5	1.2	-0.2	0.6	2.4	3.2
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	3.3	-0.3	-1.4	-1.3	0.4	0.5	1.8	-1.6	-0.2	-0.4	-1.5
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	5.1	2.3	0.3	1.3	1.4	-1.0	0.5	0.4	1.4	1.3	-0.1
Number of children fathered	1.1	1.2	3.5	1.2	0.6	-0.6	1.5	-0.3	-0.5	0.6	1.3	1.3	1.9
Hayfever, allergic rhinitis or eczema	1.0	2.2	5.9	0.3	1.7	1.6	-0.2	-1.2	-2.4	2.1	0.8	0.1	1.9
Medication: Cholesterol lowering	1.0	1.5	3.6	1.9	1.1	0.8	1.6	-1.0	-0.4	1.1	1.8	1.3	0.7
Loud music exposure frequency	1.0	1.1	3.9	0.2	0.7	0.6	2.0	-1.2	-0.3	0.6	1.7	1.2	0.4
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	3.9	0.4	1.7	1.5	1.0	-2.0	-1.5	1.6	1.4	1.2	-0.2
Pulse wave peak to peak time	1.0	1.1	2.6	0.3	1.3	0.1	1.6	-1.0	-0.8	0.9	1.0	1.6	1.0
Overall health rating	1.0	2.2	5.0	-0.2	-1.6	-1.5	-0.6	2.2	2.0	-2.0	-0.7	-0.7	-1.7
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.5	0.9	0.7	1.6	1.4	-0.5	-0.3	0.8	1.3	1.2	1.5
Loneliness, isolation	1.0	1.4	5.4	-0.5	-1.3	-0.0	-0.6	1.4	1.4	-1.2	-0.3	-0.9	-2.3
Commuting to job workplace: Walk	1.0	1.1	4.9	0.1	-0.4	-2.2	-0.9	1.6	0.3	-0.1	-0.2	-1.0	-1.0
Average weekly champagne plus white wine intake	1.0	1.4	3.9	0.5	-1.5	-1.9	0.2	-0.4	2.0	-1.5	-0.9	-0.0	0.7
Medication: Lisinopril	1.0	1.2	5.0	-1.4	-0.1	-1.8	-0.8	0.2	0.0	-0.5	-0.7	-0.9	-2.2
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.9	0.9	-0.1	-0.6	1.7	-0.1	1.1	-0.7	1.1	1.5	-1.6
Alcohol drinker status: Previous	1.0	1.1	2.2	0.1	1.5	1.0	0.5	-1.1	-1.1	1.2	0.8	1.2	1.2
Alzheimer’s Disease (in father)	0.9	1.0	3.8	1.3	0.6	1.1	0.5	-2.0	-0.3	0.5	0.6	0.9	1.0
Alzheimer’s Disease (including proxy)	0.9	1.3	6.5	2.5	-0.0	-1.1	0.3	-1.9	0.7	0.1	0.7	0.4	0.5
Coronary Artery Disease (CAD)	0.9	1.1	4.4	0.0	1.3	0.6	-0.1	-2.1	-1.0	1.1	0.6	0.7	1.4
Primary Biliary Cirrhosis	0.9	1.3	4.0	-0.9	-1.2	-0.9	-1.0	1.3	0.8	-1.0	-2.0	-1.1	0.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.6	-0.7	-1.2	-0.4	-1.5	0.8	0.5	-0.9	-1.1	-1.6	-0.7
Ulcerative Colitis	0.9	1.3	4.2	-0.1	-1.7	0.2	-0.1	1.3	1.3	-1.3	-0.4	-0.9	-2.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.6	1.9	0.4	-0.9	0.6	-1.9	-0.2	0.5	0.7	0.7	1.2
Heart attack	0.9	1.1	3.7	1.0	0.7	0.8	1.3	-1.9	-0.2	0.6	0.8	1.0	1.4
Mouth/teeth dental problems: Dentures	0.9	1.4	4.7	-0.6	0.4	0.6	-1.5	2.2	-1.0	0.9	-0.2	-1.2	-1.8
Length of working week for main job	0.9	1.0	2.3	-1.0	-0.9	-1.5	-0.8	1.5	0.3	-0.8	-0.3	-1.3	-0.8
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.2	1.4	1.2	0.3	0.0	-1.5	-1.2	1.2	0.6	0.9	1.3
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.2	-1.2	-0.9	-1.5	-1.0	1.1	0.7	-0.8	-1.2	-1.3	0.7
Medication: Ibuprofen	0.9	1.0	2.6	1.6	0.4	1.1	1.5	-0.5	0.4	0.3	1.2	1.4	-0.2
Number of full sisters	0.9	1.1	3.9	0.6	-0.5	0.0	2.0	-0.2	1.6	-1.0	0.4	1.4	-0.9
Qualifications: nursing, teaching	0.9	1.4	2.5	-0.1	-1.6	-1.5	-0.8	0.8	1.1	-1.6	-1.6	-1.1	0.9
Medication for cholesterol	0.9	1.4	5.0	0.3	0.7	0.8	2.2	-1.3	-0.1	0.5	1.2	1.4	1.7
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.7	1.2	-1.0	-1.5	-1.6	-0.8	0.5	-0.8	-1.1	-0.9	-1.1
Myopia	0.9	1.3	4.4	0.3	1.8	-0.4	-0.1	0.1	-2.1	2.0	0.8	0.3	0.3
Rheumatoid Arthritis	0.8	1.1	1.9	0.0	-1.4	-1.0	-1.3	0.7	0.9	-1.2	-1.4	-1.2	-0.7
Allergy or Eczema	0.8	2.1	6.3	0.4	1.9	1.2	-0.5	-1.4	-2.5	2.3	1.3	-0.0	0.8
Hypothyroidism (self reported)	0.8	1.8	3.3	-0.1	1.6	1.3	1.6	-1.6	-1.0	1.3	1.6	1.8	-0.1
Number of treatments/medications taken	0.8	1.4	3.2	1.5	1.6	1.3	0.1	-0.6	-1.3	1.8	1.3	0.6	0.1
Ever had hysterectomy (womb removed)	0.8	0.9	2.5	-0.7	0.6	1.3	-0.9	1.6	-1.1	0.9	-0.1	-0.4	-0.7
Depression (self-reported)	0.8	1.0	2.2	0.9	1.1	1.1	0.8	-1.5	-0.6	0.9	1.2	0.9	0.4
Headache pain in last month	0.8	1.4	5.0	1.4	0.8	-0.3	2.2	-1.0	0.1	0.5	1.3	1.6	0.8
Gout (self-reported)	0.8	1.0	2.1	0.4	1.3	0.6	0.6	-1.4	-1.4	1.3	0.8	1.0	-0.6
Number of full brothers	0.8	1.0	7.2	-2.7	0.4	0.6	0.1	1.3	-0.5	-0.1	-0.7	0.0	0.2
Health satisfaction	0.8	1.1	1.9	-0.7	-1.0	-0.7	-1.3	1.0	0.9	-1.0	-0.6	-1.3	-1.4
Medication: Omeprazole	0.8	1.0	5.1	0.1	-0.3	1.3	0.7	2.3	0.8	-0.4	0.4	0.4	-1.1
Average weekly red wine intake	0.8	1.2	2.2	-1.2	1.5	1.2	0.9	-0.5	-1.1	1.2	0.2	1.2	1.1
Age started oral contraceptive pill	0.8	1.0	2.0	-1.4	0.3	1.0	-1.4	0.6	-1.2	0.6	-0.4	-1.0	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	4.0	0.7	0.7	2.0	0.6	1.2	-0.6	0.8	1.0	0.6	-0.4
Neuroticism (Nagel 2018)	0.7	1.7	3.4	1.7	1.2	1.9	1.4	-0.7	-0.4	1.2	1.8	1.6	0.0
Ever used hormone-replacement therapy (HRT)	0.7	0.9	6.2	-0.3	-0.6	0.5	-0.9	0.1	0.3	-0.3	-0.3	-0.8	-2.5
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	2.4	0.3	0.4	-0.2	1.5	-1.0	0.3	-0.2	1.0	1.5	-0.2
Financial difficulties in last 2 years	0.7	0.9	2.6	0.5	0.4	1.6	1.4	0.3	-0.4	0.4	1.2	0.6	1.4
Mouth/teeth dental problems	0.7	1.1	2.9	0.2	-0.7	-0.3	1.7	-1.6	1.6	-1.2	0.3	1.2	0.3
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	1.8	-1.2	0.7	1.0	-1.3	0.7	-1.3	0.9	-0.5	-0.9	0.9
Neuroticism score	0.7	1.5	3.4	1.3	1.2	1.3	1.5	-0.7	-0.3	1.1	1.9	1.7	0.2
Pulse wave Arterial Stiffness index	0.7	0.9	1.8	0.0	-1.3	-0.0	-1.2	0.8	0.9	-0.9	-0.7	-1.4	-0.9
Peak expiratory flow (PEF)	0.7	1.7	4.9	-0.6	-1.6	-1.2	0.9	0.9	2.2	-1.8	-1.4	-0.1	0.9
Pulse wave reflection index	0.7	0.9	2.5	-0.1	-0.9	0.5	-1.6	0.6	0.6	-0.6	-1.0	-1.5	-1.1
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.3	0.9	1.1	1.5	0.2	0.3	-0.8	1.2	0.8	0.4	0.9
Age at first live birth	0.7	1.3	1.9	0.7	1.4	-0.3	1.3	-1.2	-1.2	1.4	1.2	1.1	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.7	0.1	-0.8	-1.3	-0.2	1.6	1.0	-0.8	-1.0	-0.4	-0.1
Mood swings	0.7	1.2	4.1	2.0	0.5	0.9	1.4	-1.0	0.2	0.5	1.5	1.2	-0.3
Eye problems/disorders: Glaucoma	0.7	0.9	2.7	-0.8	-0.6	-0.1	-1.5	0.9	0.4	-0.4	-1.2	-1.6	0.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.4	-0.7	-1.1	0.3	-1.1	0.8	0.7	-1.0	-1.0	-1.0	-1.2
Irritability	0.7	1.2	6.4	-1.7	0.1	2.5	-0.7	1.0	-0.3	0.2	-0.7	-0.5	0.3
Irritable Bowel Disease (IBD)	0.6	1.4	3.2	-0.9	-1.5	-0.5	0.1	1.5	1.5	-1.5	-0.8	-0.6	-1.8
Ulcerative Colitis (UC)	0.6	1.1	2.6	-0.9	-1.3	0.2	-0.1	1.5	0.8	-1.0	-0.9	-0.7	-1.6
Breast Cancer	0.6	1.5	4.8	-0.5	-1.3	-0.9	0.1	0.3	2.2	-1.8	-0.6	-0.0	-1.9
Ovarian Cancer	0.6	0.8	3.4	0.4	-0.6	-0.8	0.8	0.2	0.8	-0.7	0.9	0.5	-1.9
Blood Eosinophil Count	0.6	4.5	8.9	-2.1	-2.4	-1.0	-2.3	2.4	1.6	-2.3	-3.0	-2.6	-0.5
Medication for hormone replacement therapy	0.6	0.7	2.1	-0.7	0.4	0.6	-0.9	1.4	-0.8	0.7	-0.5	-0.2	-1.2
Townsend deprivation index at recruitment	0.6	0.8	3.0	-0.9	0.5	1.7	-0.3	-0.8	-0.6	0.4	-0.4	-0.2	1.6
Fed-up feelings	0.6	1.0	2.3	0.4	-1.2	-0.6	-1.2	1.5	1.0	-0.9	-0.9	-1.4	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.5	0.7	0.7	1.1	0.7	-1.1	-0.8	1.0	0.7	0.6	1.2
Medication: Levothyroxine sodium	0.6	1.0	4.5	-0.0	1.1	1.2	0.7	-2.1	-0.8	1.0	0.7	0.9	-0.4
Number of incorrect matches in round	0.6	1.0	1.9	1.4	1.1	0.4	0.9	-0.8	-1.1	1.2	1.2	1.0	0.6
Noisy workplace	0.6	0.8	2.5	0.2	1.0	0.9	0.7	-1.6	-0.7	0.9	0.8	0.9	-0.4
Medication: Lansoprazole	0.6	0.6	2.0	-0.2	0.8	0.2	-0.9	-0.6	-1.4	1.2	0.5	-0.6	0.8
Medication: Amlodipine	0.6	0.9	3.0	0.5	1.1	0.9	1.2	-0.9	-0.4	0.7	0.7	1.7	0.1
Chest pain or discomfort	0.6	0.8	2.2	-0.8	0.9	1.3	0.8	0.3	-0.8	0.9	0.6	0.5	1.5
Hypertension (Self-reported)	0.6	1.6	2.8	0.6	1.7	1.2	1.2	-1.6	-1.0	1.5	1.2	1.7	-0.2
Back pain experienced in last month	0.6	0.8	1.7	0.6	-1.3	0.3	-0.4	1.3	1.1	-0.8	-0.7	-0.9	-1.1
Guilty feelings	0.6	1.0	3.6	1.9	-0.3	0.7	1.3	-0.9	0.8	-0.1	1.2	0.8	-0.2
Mother’s age at death	0.6	0.8	3.9	-2.0	0.8	0.2	-0.6	0.7	-1.2	0.8	-0.1	-0.7	0.3
Medication: Paracetamol	0.6	0.9	3.3	0.8	0.2	1.7	1.2	-0.0	0.4	0.3	0.3	0.6	1.8
Depression (Nagel 2018)	0.5	0.8	1.6	1.0	0.6	1.3	0.9	-1.0	-0.6	0.9	1.1	0.7	0.7
Height	0.5	8.9	39.4	2.3	-0.3	0.2	6.3	-1.6	3.1	-1.6	2.5	4.7	-0.2
Cardiovascular Disease	0.5	1.7	5.0	1.2	1.4	0.8	1.6	-1.6	0.1	1.0	1.0	2.2	0.7
Lung FEV1/FVC ratio	0.5	2.6	7.1	0.3	-2.0	-2.7	-0.3	0.4	2.6	-2.2	-1.5	-0.8	-0.3
Neuroticism	0.5	1.2	2.5	1.1	1.0	1.2	1.3	-0.9	0.0	0.9	1.6	1.4	0.6
Qualifications: None of the above	0.5	1.0	2.7	-0.5	-0.6	1.7	-1.6	0.7	-0.1	-0.1	-0.8	-1.5	-1.0
Standing height	0.5	5.3	15.7	1.7	-2.0	-1.3	4.0	-0.8	3.9	-2.8	0.4	2.4	-0.2
Hair/balding pattern: Pattern 4	0.5	1.1	2.3	-0.6	-1.1	-1.2	-1.3	0.5	0.6	-0.8	-1.5	-1.4	-1.0
Birth weight of first child	0.5	1.0	1.9	1.0	-0.8	-0.5	1.4	0.7	1.2	-1.0	0.9	0.6	-1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.7	-1.3	-0.7	0.1	-1.3	1.3	-0.2	-0.5	-1.0	-1.3	-0.2
High blood pressure (siblings)	0.5	0.7	2.6	-0.6	-0.4	-0.5	-1.5	0.6	-0.4	0.1	-0.9	-1.6	-0.5
Qualifications: College or University degree	0.5	1.7	3.9	0.9	1.3	0.6	1.9	-1.8	-1.0	1.1	1.2	2.0	0.6
Medication: Blood pressure	0.5	0.9	3.1	0.9	0.8	0.3	1.1	-1.7	-0.5	0.8	1.1	1.1	-0.6
Had major operations	0.5	0.6	2.9	-0.3	-0.1	-0.5	0.5	1.7	-0.1	-0.4	0.9	0.1	-1.2
Breast cancer (self-reported)	0.5	0.6	1.1	-0.9	1.0	0.9	-0.2	0.1	-1.1	0.9	-0.1	0.3	0.9
Number of self-reported non-cancer illnesses	0.5	0.9	2.0	0.2	1.1	1.3	0.8	-0.4	-0.5	0.9	1.4	1.1	-0.8
Average weekly beer plus cider intake	0.5	0.7	3.1	1.4	-0.3	-0.0	1.0	0.3	0.4	-0.1	0.1	0.4	1.8
Intelligence (Savage-Jansen 2018)	0.4	1.2	2.9	-0.8	1.0	1.7	1.5	-0.1	-0.5	0.6	1.2	1.4	1.0
Major Depression (MDD)	0.4	0.5	1.7	0.2	0.4	1.3	0.9	-0.3	-0.0	0.2	0.7	0.7	1.2
Verbal and Numeric Reasoning (VNR)	0.4	1.1	1.8	-0.5	1.3	1.2	1.2	-0.8	-0.8	0.9	1.4	1.2	0.7
Mean Putamen Volume	0.4	0.5	1.6	0.3	-0.9	-0.3	-0.7	-0.4	0.5	-0.7	-0.8	-1.2	-0.4
Respiratory disease	0.4	0.9	3.6	-1.1	0.7	0.0	-0.3	1.1	-1.3	0.8	-0.3	-0.5	1.9
Sensitivity / hurt feelings	0.4	0.6	1.6	-0.7	-0.5	-0.8	-1.0	1.0	0.5	-0.6	-1.3	-0.5	-0.6
Serious illness, injury or assault to yourself	0.4	0.5	1.4	0.7	0.4	1.2	0.5	0.9	-0.4	0.8	1.1	0.0	-0.3
High blood pressure	0.4	1.1	2.0	0.5	1.4	0.8	0.9	-1.4	-0.8	1.2	1.0	1.4	-0.4
Sitting height	0.4	2.9	12.7	1.2	-0.8	-0.8	3.6	-0.4	2.2	-1.3	1.2	2.4	0.3
High blood pressure (mother)	0.4	0.6	2.4	-1.3	0.3	-0.4	0.0	-1.0	-0.4	0.4	-0.3	-0.0	1.6
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	1.1	-0.1	1.3	1.1	-0.7	0.7	0.0	0.9	0.4	0.6
Had menopause	0.4	0.5	3.6	0.1	-0.0	0.2	-0.7	0.3	-0.4	0.3	0.1	-0.7	-1.9
Had other major operations	0.4	0.5	1.1	-0.9	-0.7	-0.3	-0.3	0.5	0.7	-0.7	-0.7	-0.6	-1.1
Illnesses of siblings	0.4	0.6	2.0	1.4	-0.1	-0.4	0.9	-0.6	0.3	-0.2	0.4	0.8	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.9	-1.0	-0.7	-0.4	-0.4	1.7	0.4	-0.5	-0.3	-1.0	0.3
Asthma	0.4	0.8	2.5	-1.3	0.6	0.1	-0.1	1.1	-1.2	0.6	0.1	-0.4	1.6
Illnesses of mother	0.4	0.5	1.6	1.3	0.5	-0.0	-1.0	0.5	-0.8	0.6	0.4	0.0	-1.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	4.7	0.1	-0.4	-2.2	-0.1	0.3	0.3	-0.3	0.5	-0.5	-0.0
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.6	-0.8	-0.6	1.3	-0.6	0.7	0.0	-0.3	-0.8	-0.7	-0.4
Emphysema/chronic bronchitis	0.4	0.4	1.1	-0.3	-0.9	0.4	-0.6	1.0	0.6	-0.8	-0.4	-0.4	-0.5
Heart disease (mother)	0.4	0.5	1.3	1.1	0.8	-0.1	0.5	-0.2	-0.9	0.9	0.6	0.4	0.6
Comparative height size at age 10	0.4	2.1	7.0	-0.1	-2.1	-1.3	0.6	-0.1	2.6	-2.3	-1.5	0.1	-0.3
Illnesses of father: Heart disease	0.4	0.5	1.5	-1.2	-0.2	0.1	-0.7	1.0	-0.5	0.1	-1.0	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	2.9	1.0	0.1	0.7	1.1	-0.8	0.1	0.0	0.1	1.0	1.7
Eye problems/disorders: Cataract	0.4	0.5	0.9	0.5	-0.9	-0.7	-1.0	0.2	0.3	-0.7	0.3	-0.9	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.6	-1.3	-0.2	0.5	-1.0	0.5	-0.5	-0.1	-0.9	-1.2	0.8
Asthma (self-reported)	0.4	0.9	3.7	-0.7	1.0	0.1	0.4	0.5	-1.3	1.0	0.5	0.2	1.9
Miserableness	0.4	0.7	1.8	0.8	0.9	0.7	0.8	0.2	-0.5	0.8	1.4	0.8	0.9
Commuting to job workplace: Public transport	0.4	0.5	1.2	0.4	0.9	0.3	0.4	-0.2	-0.9	1.1	0.8	0.7	0.3
Number of operations (self-reported)	0.4	0.5	2.4	0.1	-0.3	0.2	0.1	1.1	0.7	-0.6	0.9	0.1	-1.5
Pain experienced in last month	0.4	0.7	1.8	0.3	0.9	-0.5	0.7	-1.0	-0.8	0.7	1.4	0.9	0.4
Supplements: Calcium	0.4	0.5	1.8	0.7	-0.1	0.5	-1.4	0.8	-0.1	0.3	0.2	-1.1	-0.2
Schizophrenia vs Biploar Disorder	0.3	0.4	1.4	0.1	-0.7	-0.7	-0.3	-0.6	0.5	-0.5	0.1	-0.7	-1.2
Alzheimer’s Disease (in mother)	0.3	0.3	1.4	0.8	0.4	-0.6	0.5	-1.2	0.3	0.3	0.2	0.5	0.2
Crohns Disease (2012)	0.3	0.5	1.7	0.6	0.5	0.4	1.3	-1.0	0.2	0.1	1.0	0.9	0.2
Lupus	0.3	0.4	0.7	0.6	0.7	0.6	0.8	-0.2	-0.2	0.8	0.8	0.7	-0.6
Blood White Count	0.3	2.0	8.1	1.3	-0.9	-1.0	-1.5	2.0	0.2	-0.4	-1.2	-1.1	2.8
Hearing difficulty/problems: Yes	0.3	0.4	1.4	-1.2	0.5	0.1	0.4	0.8	-0.5	0.3	0.2	0.3	-1.0
Medication: Co-codamol	0.3	0.3	0.8	-0.0	0.6	0.4	-0.6	-0.9	-0.7	0.7	0.2	-0.3	0.6
Relative age voice broke	0.3	0.4	1.1	-0.6	-0.5	-0.6	-0.9	0.1	0.2	-0.2	-0.8	-1.0	0.6
Stomach or abdominal pain in last month	0.3	0.3	0.8	0.4	0.3	-0.3	-0.5	-0.3	-0.9	0.8	0.0	-0.5	0.8
Medication: Atenolol	0.3	0.3	0.9	-0.3	0.7	-0.6	1.0	-0.5	-0.2	0.6	0.7	0.3	0.1
Allergy	0.3	0.8	2.1	1.5	-0.3	-0.4	1.1	-0.4	1.1	-0.5	0.9	1.0	-0.8
Medication: Ramipril	0.3	0.3	1.9	0.5	0.5	0.6	-0.3	-1.4	-0.2	0.6	-0.1	0.2	0.2
Qualifications: A levels/AS levels or equivalent	0.3	0.8	2.8	0.3	0.7	0.1	1.7	-1.1	-0.2	0.5	0.9	1.2	0.7
Lung cancer (father)	0.3	0.4	1.8	-0.3	-0.8	0.3	0.2	0.6	1.3	-0.7	-0.6	-0.5	0.1
Exposure to tobacco smoke outside home	0.3	0.3	1.7	-0.2	-0.3	1.3	-0.9	0.3	-0.0	-0.0	-0.3	-0.8	-0.3
Worry too long after embarrassment	0.3	0.6	1.7	0.4	0.8	0.4	0.9	0.1	-0.1	0.5	0.7	1.1	-1.3
Neck or shoulder pain in last month	0.3	0.5	3.0	0.5	-0.2	1.7	-0.3	0.9	-0.1	0.1	-0.2	-0.5	-0.6
Medication: Seretide 50 evohaler	0.3	0.3	0.8	0.9	-0.0	0.7	0.7	-0.6	0.5	-0.1	0.2	0.8	0.4
Age at last live birth	0.3	0.4	0.8	0.4	0.3	-0.0	0.8	-0.8	-0.4	0.3	0.9	0.6	-0.9
Leg pain on walking	0.3	0.3	0.9	-0.8	-0.4	0.3	-0.9	0.2	0.2	-0.5	-0.8	-0.7	-0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.7	-0.8	0.4	-0.4	-0.3	-1.6	-0.1	-0.0	-0.3	0.5	-0.4
Medication: Aspirin	0.3	0.4	1.4	1.0	0.1	1.2	0.7	-0.5	-0.2	0.3	0.9	0.3	-0.2
Ever had bowel cancer screening	0.3	0.3	1.0	-0.8	0.7	0.4	-0.0	-0.3	-0.5	0.4	0.0	0.5	-1.0
Friendships satisfaction	0.3	0.4	1.2	0.8	-0.2	0.1	1.1	-0.3	0.7	-0.7	0.3	0.8	0.4
Medication: Aspirin	0.3	0.3	1.1	0.9	-0.2	1.1	0.7	-0.3	0.3	-0.1	0.7	0.2	-0.4
Medication: Gliclazide	0.3	0.3	0.9	-0.6	-0.5	0.2	0.0	0.9	0.8	-0.7	-0.7	-0.0	-0.6
High cholesterol (Self-reported)	0.3	0.5	1.7	1.3	-0.8	-0.1	-0.5	0.5	0.8	-0.6	0.0	-0.5	-0.9
Medication: Bendroflumethiazide	0.3	0.5	2.3	-0.6	0.4	0.9	0.4	0.0	0.1	0.0	0.5	0.7	-1.5
Diastolic blood pressure, automated reading	0.3	1.0	2.4	0.9	0.9	-0.6	1.3	-1.3	-0.5	0.6	1.0	1.6	-0.6
Ever depressed for a whole week	0.3	0.4	0.9	-0.9	-0.6	0.4	-0.8	0.2	0.4	-0.7	-0.9	-0.7	0.4
Heart disease (siblings)	0.3	0.4	1.9	-1.4	-0.3	-0.2	-0.2	0.0	0.6	-0.6	-0.2	-0.2	-1.0
Depressed Affect (Nagel 2018)	0.2	0.3	1.5	0.0	-0.3	0.5	-0.4	0.6	0.5	-0.2	0.5	-0.5	-1.2
LDL Cholesterol	0.2	0.3	1.8	1.3	0.2	-0.1	0.1	-0.3	0.0	0.2	0.5	0.5	0.4
Relative age of first facial hair	0.2	0.4	0.9	-0.8	0.6	-0.1	-0.3	0.3	-1.0	0.7	-0.5	-0.4	0.8
Angina	0.2	0.3	0.9	-0.7	0.1	0.3	0.9	-0.5	0.2	-0.3	0.7	0.5	-0.0
Age when periods started (menarche)	0.2	0.4	2.9	-0.1	-0.1	-0.0	0.7	-1.7	0.4	-0.6	-0.1	0.8	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.0	-0.1	0.1	-0.9	-1.0	0.3	-0.9	0.5	-0.9	-0.5	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.6	-0.1	-0.5	-1.1	-1.2	0.2	-0.2	-0.1	-1.3	-0.9	-0.1
Pain all over the body in last month	0.2	0.3	0.6	-0.3	-0.3	-0.2	-0.8	0.3	0.6	-0.5	-0.8	-0.5	0.4
Fluid intelligence score	0.2	0.4	1.2	-0.0	-0.7	-0.1	0.5	-0.4	1.1	-1.1	0.1	0.3	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	1.2	0.8	0.2	0.7	0.6	0.4	0.0	0.3	1.1	0.4	0.3
Happiness	0.2	0.3	1.3	0.5	-0.3	0.5	0.4	-1.2	0.1	-0.2	0.7	0.3	0.5
Exposure to tobacco smoke at home	0.2	0.2	0.8	0.2	-0.4	-0.9	-0.6	-0.2	0.4	-0.3	-0.4	-0.6	0.3
Blood clot in the leg (DVT)	0.2	0.3	1.7	-1.3	0.2	0.4	-0.1	-0.6	-0.0	-0.1	-0.4	0.2	-0.6
Angina (self-reported)	0.2	0.3	0.9	-0.8	0.1	0.5	1.0	-0.4	0.2	-0.2	0.6	0.6	0.1
Medication: Allopurinol	0.2	0.3	0.7	-0.7	0.4	-0.3	-0.1	-0.8	-0.7	0.4	-0.5	0.0	-0.6
Alcohol intake frequency.	0.2	0.4	1.6	-1.3	-0.3	-0.1	-0.8	-0.3	0.4	-0.6	-0.6	-0.2	-1.0
Family relationship satisfaction	0.2	0.3	0.7	-0.4	0.3	0.9	0.8	-0.4	-0.2	0.1	0.6	0.5	0.6
Smoking status: Previous	0.2	0.3	0.7	0.8	-0.6	-0.1	0.2	0.8	0.6	-0.8	0.0	-0.0	-0.1
Osteoarthritis (self-reported)	0.2	0.2	0.9	0.8	-0.1	-0.5	0.0	-0.9	0.3	-0.1	0.1	0.4	-0.5
Financial situation satisfaction	0.2	0.3	0.8	0.4	0.4	0.4	0.5	-0.9	-0.7	0.4	0.8	0.2	0.4
Medication: Blood pressure	0.2	0.4	1.4	0.7	0.2	-0.7	-0.9	-0.5	0.2	-0.1	-0.1	-0.0	-1.2
Medication: Atorvastatin	0.2	0.2	0.8	-0.4	0.2	-0.9	0.4	0.2	0.1	-0.2	0.2	0.4	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.6	-0.0	-1.0	-0.6	-0.7	1.3	0.3	-0.7	-0.8	-1.1	0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.9	-1.0	0.5	0.7	0.0	-0.5	-0.4	0.2	-0.1	0.5	-0.4
Crohns Disease (2017)	0.1	0.3	1.2	-0.2	-0.5	-0.4	0.5	0.4	1.1	-0.8	-0.3	0.1	-0.5
Heel T-Score	0.1	1.1	3.4	0.3	-0.2	-0.9	-1.8	0.1	-0.5	0.3	-1.2	-1.2	-1.8
Hair Pigment	0.1	2.0	4.3	0.3	2.1	0.5	0.3	-2.0	-1.9	2.0	1.5	0.9	0.3
Tanning	0.1	1.1	4.0	1.0	0.6	2.0	0.8	-1.4	-1.0	0.8	0.7	0.5	0.9
Systolic blood pressure, automated reading	0.1	0.3	1.0	1.0	0.1	-0.3	0.4	-0.9	0.1	0.1	0.3	0.4	-0.7
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	-0.5	-0.1	0.3	-0.3	0.3	0.3	-0.4	0.2	-0.1	0.2
Medication: Simvastatin	0.1	0.2	0.6	0.7	-0.5	0.1	-0.0	-0.1	0.8	-0.4	-0.1	-0.1	-0.4
Prospective memory result	0.1	0.1	0.5	0.6	-0.2	-0.0	0.3	0.7	0.4	-0.1	0.0	0.1	0.2
Glaucoma (self-reported)	0.1	0.1	0.6	-0.3	-0.0	0.0	-0.7	-0.1	0.3	-0.0	-0.2	-0.6	0.3
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.1	0.0	0.0	0.4	-0.3	0.3	-0.2	0.2	0.3	-0.6
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	-0.2	0.0	0.3	-0.3	0.3	-0.4	-0.1	0.5	-0.1	-0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.4	1.5	0.8	-0.5	-0.0	1.2	0.6	0.4	-0.1	0.4	0.5	0.5

Hub : Genes

RGS17

Models

Trait associations