[Hub]/) : Traits : Whole body water mass :

chr8:56,094,665-57,683,880

Best TWAS P=2.11e-30 · Best GWAS P=6.36e-53 conditioned to 1.09e-27

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-446E9.1 0.07 0.00 lasso 6 0.00 6.6e-01 -6.9 8.3 1.2e-16 -0.76 0.03 0.70 FALSE
2 GTEx Brain Cerebellum RPS20 0.26 0.07 enet 17 0.10 5.4e-04 -10.1 -8.8 1.2e-18 0.60 0.18 0.55 FALSE
3 GTEx Brain Cerebellum RP11-446E9.1 0.15 0.05 lasso 3 0.03 3.7e-02 -6.7 6.5 5.7e-11 -0.53 0.05 0.51 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia RPS20 0.41 0.05 lasso 8 0.13 3.1e-04 -7.3 -6.8 1.1e-11 0.53 0.04 0.34 FALSE
5 GTEx Cells EBV-transformed lymphocytes LYN 0.35 0.07 enet 37 0.17 4.5e-06 11.0 -5.5 4.3e-08 -0.07 0.15 0.05 TRUE
6 GTEx Esophagus Muscularis RPS20 0.12 0.04 lasso 6 0.05 7.2e-04 -10.1 -9.9 2.6e-23 0.76 0.20 0.66 FALSE
7 GTEx Muscle Skeletal RPS20 0.07 0.09 lasso 1 0.07 1.5e-07 -6.6 -6.6 3.8e-11 0.49 0.95 0.05 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic RPS20 0.18 0.03 enet 12 0.07 1.5e-04 -9.7 -11.5 2.1e-30 0.81 0.13 0.53 TRUE
9 GTEx Stomach RP11-446E9.1 0.12 0.08 lasso 4 0.03 1.7e-02 -6.2 6.1 1.4e-09 -0.48 0.28 0.15 FALSE
10 ROSMAP Brain Pre-frontal Cortex RPS20 0.24 0.20 lasso 6 0.23 3.4e-29 -8.4 -7.4 1.5e-13 0.51 1.00 0.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex RP11-446E9.1 0.23 0.32 lasso 7 0.34 2.0e-45 -6.6 7.6 2.4e-14 -0.53 1.00 0.00 FALSE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma PENK 0.03 0.01 blup 40 0.03 9.1e-04 -4.9 -5.3 8.7e-08 -0.01 0.02 0.70 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma PENK 0.11 0.13 lasso 2 0.14 2.6e-08 -5.1 -5.3 9.5e-08 0.06 0.01 0.99 FALSE
14 The Cancer Genome Atlas Esophageal Carcinoma PENK 0.35 0.21 enet 12 0.33 3.8e-11 4.5 -5.2 2.7e-07 -0.02 0.04 0.94 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PENK 0.07 0.06 enet 8 0.08 2.4e-09 -4.7 -5.4 8.2e-08 0.04 0.02 0.97 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS20 0.04 0.02 blup 29 0.03 4.8e-04 -8.2 -7.4 1.0e-13 0.49 0.03 0.03 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma RPS20 0.33 0.07 enet 8 0.07 1.7e-08 -8.4 -9.6 1.1e-21 0.49 0.96 0.03 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma RPS20 0.04 0.03 lasso 3 0.04 1.3e-04 -8.4 -8.4 6.0e-17 0.58 0.15 0.05 FALSE
19 The Cancer Genome Atlas Rectum Adenocarcinoma PENK 0.18 0.11 lasso 1 0.09 3.4e-03 -5.1 -5.1 2.8e-07 0.08 0.01 0.56 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma LYN 0.09 0.12 lasso 2 0.12 8.4e-12 -6.2 6.2 5.1e-10 -0.49 1.00 0.00 FALSE