TWAS hub - LYN

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.2592	0.0716	6.9e-05	0.138	NA	0.097	NA	0.126	6.0e-11	NA	4.6e-08	NA	4.5e-10
2	GTEx	Brain Cerebellar Hemisphere	0.4490	0.1450	2.4e-03	0.011	NA	0.153	NA	0.116	1.6e-01	NA	9.9e-05	NA	6.7e-04
3	GTEx	Brain Cerebellum	0.1980	0.0720	2.8e-03	0.104	NA	0.070	NA	0.166	5.5e-04	NA	4.2e-03	NA	1.2e-05
4	GTEx	Cells EBV-transformed lymphocytes	0.3540	0.0960	1.6e-04	0.068	NA	0.166	NA	0.091	3.0e-03	NA	4.5e-06	NA	6.9e-04
5	GTEx	Cells Transformed fibroblasts	0.4610	0.0660	5.8e-13	0.327	NA	0.300	NA	0.324	3.7e-25	NA	7.9e-23	NA	6.8e-25
6	GTEx	Spleen	0.2460	0.0900	4.2e-03	0.000	NA	0.019	NA	0.013	3.2e-01	NA	1.1e-01	NA	1.5e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0962	0.0272	8.1e-09	0.048	0.078	0.082	0.079	0.090	7.4e-07	2.7e-10	9.8e-11	2.6e-10	1.1e-11
8	TCGA	Thyroid Carcinoma	0.0940	0.0350	1.3e-08	0.121	0.095	0.107	NA	0.121	7.7e-12	1.8e-09	1.5e-10	NA	8.3e-12

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
High blood pressure (mother)	3.5	4.9	12.2	2.7	-1.3	-2.1	0.6	2.5	-1.1	-3.5	-2.3
Illnesses of siblings: Diabetes	3.5	4.3	7.6	2.1	-2.8	-2.4	0.3	2.3	-1.5	-1.9	-2.4
Eye problems/disorders: Diabetes related eye disease	2.9	3.2	6.4	-2.0	2.3	1.9	0.4	-1.6	0.9	1.7	2.5
Diabetes diagnosed by doctor	2.9	4.8	9.4	-1.8	2.6	3.0	-0.6	-1.5	3.1	1.3	2.4
Lupus	2.8	4.3	12.5	-2.3	1.1	2.6	0.3	-2.4	0.4	1.5	3.5
Asthma	2.8	5.5	11.3	-2.3	3.4	1.9	0.7	-2.4	2.6	2.6	2.0
Ever had stillbirth, spontaneous miscarriage or termination	2.8	3.0	8.1	2.9	-1.9	-1.0	0.2	2.6	-1.6	-0.3	-1.4
Trunk fat-free mass	2.5	14.3	48.0	-2.2	0.6	1.8	-5.7	-2.5	2.0	3.9	6.9
Trunk predicted mass	2.5	14.4	47.7	-2.3	0.6	1.9	-5.6	-2.6	2.0	4.0	6.9
Asthma (self-reported)	2.5	4.9	9.6	-2.3	3.1	1.6	1.2	-2.5	2.2	2.4	1.9
Financial situation satisfaction	2.5	3.1	7.5	1.4	-2.2	-1.4	0.1	1.3	-2.7	-1.5	-2.1
Alzheimer’s Disease (including proxy)	2.4	3.5	10.1	2.2	-0.4	-1.0	1.5	2.4	-1.6	-1.0	-3.2
Respiratory disease	2.4	5.3	9.4	-3.1	2.0	1.9	0.7	-3.0	2.5	2.2	2.2
Illnesses of mother	2.4	3.0	6.5	-2.3	1.0	1.5	-0.0	-2.0	0.1	2.5	2.2
Medication: Seretide 50 evohaler	2.4	2.7	6.8	-1.2	1.9	1.5	0.8	-1.2	2.6	1.6	1.7
Ever had bowel cancer screening	2.4	2.8	5.7	-1.5	2.4	2.1	-0.8	-1.6	1.8	1.2	1.7
Illnesses of siblings	2.3	3.2	6.5	-2.2	2.3	1.5	0.1	-2.5	0.2	2.1	1.6
Medication: Metformin	2.2	3.1	10.0	-1.3	1.5	2.1	-0.8	-1.1	3.2	1.1	1.7
Medication: Paracetamol	2.2	3.6	6.8	1.2	-2.5	-0.9	0.2	1.3	-2.5	-2.4	-2.6
Comparative height size at age 10	2.2	11.8	46.8	-1.9	-0.5	0.9	-6.8	-1.9	1.8	1.4	5.9
Medication: Gliclazide	2.2	2.5	4.0	-1.4	1.9	2.0	0.7	-1.4	1.8	1.4	1.5
Bipolar Disorder (2018)	2.1	3.3	8.2	-1.9	1.0	2.9	-0.1	-2.1	0.9	1.6	2.4
Height	2.1	39.8	134.6	-4.3	-1.2	3.2	-11.6	-4.5	3.8	3.9	10.2
Sitting height	2.1	14.6	75.9	-1.7	-0.2	1.5	-8.7	-1.7	3.8	-0.0	4.3
Glaucoma (self-reported)	2.1	2.5	4.9	-2.2	1.6	0.6	1.0	-2.1	2.2	1.2	0.8
Medication: Aspirin	2.1	2.7	9.3	-1.4	1.6	1.8	0.1	-1.4	1.5	0.8	3.0
Ever had prostate specific antigen (PSA) test	2.1	2.4	4.5	-1.2	1.4	2.1	-0.9	-1.7	0.6	1.8	2.0
Ovarian Cancer	2.0	2.6	5.8	-0.5	2.3	2.2	0.3	-0.4	2.4	1.6	1.2
HbA1C	2.0	2.3	11.4	-0.1	1.0	0.4	-0.7	-0.1	-0.2	2.2	3.4
Blood Platelet Count	2.0	23.7	56.1	4.4	-6.7	-5.1	1.8	4.3	-7.5	-4.7	0.1
Type 2 Diabetes (T2D) (2018)	2.0	3.8	8.6	-1.9	1.6	2.9	-1.9	-1.5	2.9	-0.2	1.3
Supplements: Glucosamine	2.0	2.6	11.5	-1.2	-1.1	-0.1	-3.4	-1.7	-1.8	-0.0	0.8
Whole body fat-free mass	2.0	11.2	38.1	-1.6	0.4	1.3	-5.4	-1.8	1.9	3.4	6.2
Whole body water mass	2.0	11.5	38.7	-1.6	0.5	1.3	-5.5	-1.8	1.9	3.5	6.2
Standing height	1.9	18.4	82.4	-2.2	-0.4	1.8	-9.1	-2.4	3.0	1.7	6.2
Arm fat-free mass (right)	1.9	9.5	33.3	-1.4	-0.1	1.0	-5.2	-1.6	1.7	2.7	5.8
Medication: Blood pressure	1.9	3.3	5.5	2.3	-0.7	-2.0	-0.9	2.3	2.3	-2.1	0.7
Arm predicted mass (right)	1.9	9.6	33.7	-1.3	-0.1	1.1	-5.1	-1.5	1.8	3.0	5.8
Crohns Disease (2017)	1.8	4.0	11.0	1.8	-1.4	-2.2	1.6	1.8	-3.3	-1.5	-1.6
Medication: Levothyroxine sodium	1.8	3.0	8.5	-2.9	0.8	1.7	0.4	-2.9	-0.1	1.1	1.4
Hair/balding pattern: Pattern 2	1.8	2.3	5.1	2.1	-1.5	-0.5	0.5	2.0	1.4	-0.8	-2.3
High blood pressure (siblings)	1.8	2.6	6.7	2.5	-1.5	-0.9	-0.5	2.6	0.1	-1.8	-1.1
Medication: Aspirin	1.8	2.3	6.8	-1.4	1.3	1.7	-0.1	-1.3	1.9	0.4	2.6
Arm predicted mass (left)	1.8	8.9	29.3	-1.7	0.5	1.1	-4.8	-1.9	1.5	2.8	5.4
Irritable Bowel Disease (IBD)	1.7	4.0	7.8	1.9	-1.6	-2.3	1.7	1.8	-2.8	-1.7	-1.8
Mean Putamen Volume	1.7	2.0	5.4	0.5	-1.9	-1.3	-1.9	0.6	0.8	-2.3	-0.0
Qualifications: CSEs or equivalent	1.7	2.2	4.5	2.1	-0.6	-0.7	2.0	2.1	-0.2	-0.6	-1.8
Number of incorrect matches in round	1.7	2.7	6.3	-2.5	0.0	0.4	-0.1	-2.4	-0.8	2.1	2.2
Diabetes (self-reported)	1.7	2.6	6.9	-0.9	1.6	2.4	-0.8	-0.6	2.6	0.2	1.8
Medication for cholesterol, blood pressure or diabetes	1.7	2.8	5.7	-2.0	1.1	2.0	0.5	-2.1	-1.7	2.4	-0.2
Emphysema/chronic bronchitis	1.7	1.9	5.0	-2.2	0.1	1.7	0.1	-2.1	1.6	-0.3	0.1
Eye problems/disorders: Glaucoma	1.7	2.0	4.1	-2.0	1.1	1.0	1.3	-1.8	1.8	1.2	0.2
Arm fat-free mass (left)	1.7	8.9	28.9	-1.7	0.4	1.2	-4.9	-2.0	1.6	2.7	5.4
Depression (Nagel 2018)	1.6	2.3	6.0	-0.4	1.6	1.3	2.4	-0.5	0.5	2.0	2.0
Age at First Birth	1.6	2.4	5.9	-1.0	1.2	1.8	0.1	-1.3	0.7	2.4	2.3
Angina	1.6	2.1	6.8	-1.6	0.9	1.3	0.1	-1.6	2.6	0.4	1.6
Diabetes (father)	1.6	2.0	6.8	-1.8	-1.4	0.6	-2.6	-1.8	-0.3	-0.6	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	5.7	-0.7	1.2	1.5	2.0	-0.8	-0.2	1.6	2.4
Allergy	1.6	3.7	6.4	2.4	-2.1	-2.1	-0.0	2.5	-1.3	-1.1	-2.5
Hypertension (Self-reported)	1.6	4.4	8.7	2.8	-1.3	-2.3	0.3	2.9	1.4	-2.8	-1.2
Average weekly red wine intake	1.6	2.4	4.0	-1.3	1.6	2.0	-1.6	-1.3	1.1	1.4	1.8
Illnesses of father: None of the above (group 1)	1.6	2.0	6.2	-2.4	1.4	0.6	-0.9	-2.5	1.0	0.3	0.2
Basal metabolic rate	1.6	8.7	30.6	-1.0	0.2	0.8	-4.9	-1.2	1.7	2.9	5.5
Number of operations (self-reported)	1.6	2.3	5.0	2.1	-1.8	0.1	-2.2	1.8	-0.4	-0.5	-1.4
Supplements: Calcium	1.6	1.7	2.8	-1.5	1.5	1.0	-1.2	-1.4	0.3	1.7	1.6
Sensitivity / hurt feelings	1.5	2.6	6.2	1.9	-1.4	-1.4	-0.3	1.8	-0.7	-2.5	-1.8
Diabetes (mother)	1.5	1.9	3.9	2.0	-1.1	-1.1	-1.6	1.7	0.1	-1.7	-0.8
Maternal smoking around birth	1.5	2.2	5.4	0.7	1.3	0.8	2.1	0.7	0.3	2.3	2.1
Loud music exposure frequency	1.5	1.6	3.9	-1.1	1.6	1.4	-0.3	-1.2	-0.2	1.4	2.0
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	7.0	1.9	-0.2	-0.9	2.6	1.7	-0.8	-0.4	-0.4
Number of full brothers	1.5	1.9	7.1	0.2	-2.7	-0.9	0.6	0.3	-1.5	-1.8	-1.0
Eye problems/disorders: None of the above	1.5	1.8	3.7	1.0	-1.7	-1.8	0.4	1.0	-1.9	-0.8	-1.3
Mean time to correctly identify matches	1.5	2.8	6.0	-1.7	1.9	1.6	-1.7	-1.8	0.2	0.8	2.4
Bipolar Disorder or Schizophrenia	1.4	3.3	9.7	-2.2	0.7	3.1	0.5	-2.3	1.4	1.3	1.6
Alzheimer’s Disease (in mother)	1.4	1.7	3.6	1.8	0.1	-0.7	1.0	1.9	-0.3	-1.4	-1.7
Fasting Glucose	1.4	1.7	3.7	1.2	-1.9	-1.5	-1.3	1.3	0.9	-1.2	-0.5
Supplements: Zinc	1.4	1.5	4.4	-0.0	0.5	1.1	-2.1	-0.1	0.2	1.5	2.0
Medication: Co-codamol	1.4	1.6	2.9	-1.1	-1.4	-1.5	-1.2	-1.0	-1.3	-0.4	1.7
Leg fat-free mass (left)	1.4	7.3	24.6	-0.6	0.4	0.6	-4.7	-0.7	1.5	2.8	5.0
Leg predicted mass (left)	1.4	7.5	25.4	-0.5	0.5	0.6	-4.7	-0.7	1.5	2.9	5.0
Alcohol intake versus 10 years previously	1.4	2.2	5.8	0.5	-2.4	-1.2	-1.7	0.6	-0.9	-2.3	-0.5
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.2	5.6	2.1	-1.6	-0.3	1.8	2.4	-1.0	-0.8	-0.4
Forced vital capacity (FVC), Best measure	1.4	5.1	11.1	-1.4	1.3	1.5	-3.1	-1.9	0.4	3.2	3.3
Illnesses of father: Heart disease	1.4	1.9	7.2	2.5	-0.3	-0.8	-0.3	2.7	0.1	0.3	0.8
Mineral and other dietary supplements	1.4	1.9	4.1	0.8	0.2	-1.3	2.0	1.0	0.4	-2.0	-1.8
Leg predicted mass (right)	1.4	7.3	24.2	-0.3	0.5	0.5	-4.7	-0.5	1.5	2.9	4.9
Blood Eosinophil Count	1.3	9.8	15.4	-3.6	3.1	3.3	-0.7	-3.6	2.6	3.1	3.9
Cardiovascular Disease	1.3	4.4	10.6	2.0	-0.9	-2.7	0.7	2.5	1.2	-3.2	-2.1
Lung FVC	1.3	6.8	28.2	0.0	2.2	1.4	1.2	-0.7	-1.3	5.3	3.9
Severe depression (siblings)	1.3	1.4	2.8	1.6	-1.0	-1.6	1.0	1.7	-1.1	-0.4	-0.4
Multivitamins +/- minerals	1.3	1.6	4.3	2.1	-0.3	-1.2	-1.9	1.7	-0.5	0.6	0.2
Impedance of leg (left)	1.3	6.3	21.3	0.6	-2.2	-1.2	0.9	0.9	-0.7	-4.5	-4.6
Alcohol usually taken with meals	1.3	2.1	4.8	-1.5	2.2	2.1	-0.8	-1.6	0.3	1.3	0.8
Gout (self-reported)	1.3	1.8	5.0	2.2	-0.1	0.2	-0.7	2.2	1.7	-1.0	-0.6
Angina (self-reported)	1.3	1.7	5.6	-1.2	0.9	1.1	-0.2	-1.2	2.4	0.3	1.7
Leg fat-free mass (right)	1.3	7.2	24.5	-0.3	0.4	0.4	-4.7	-0.4	1.4	2.8	4.9
Medication: Paracetamol	1.3	2.0	5.6	1.2	-2.4	-0.5	0.6	1.1	-1.6	-1.6	-1.6
Medication: Lisinopril	1.3	1.7	4.9	0.9	-1.3	-2.2	0.0	1.0	0.1	-2.1	-0.9
Impedance of whole body	1.3	6.8	27.0	1.2	-1.7	-1.0	0.9	1.6	-0.8	-4.2	-5.2
Alzheimer’s Disease (in father)	1.2	1.3	4.8	0.5	0.5	-0.5	1.2	0.6	-2.2	-0.3	-1.9
Taking other prescription medications	1.2	1.8	7.7	-0.1	-0.4	1.4	-1.6	0.1	1.3	0.7	2.8
High blood pressure	1.2	3.2	6.0	2.3	-1.1	-2.0	0.1	2.4	1.4	-2.4	-1.0
Diverticular disease/diverticulitis (self-reported)	1.2	1.5	4.9	-1.3	2.2	1.0	1.3	-1.5	-0.4	0.2	-0.1
Had other major operations	1.2	1.5	5.5	0.7	-1.2	0.3	-2.3	0.6	-0.5	-1.6	-1.1
Ever highly irritable/argumentative for 2 days	1.2	1.5	4.5	0.3	-0.2	0.8	2.0	0.2	0.8	1.4	2.1
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.4	15.5	-0.2	-0.1	0.4	-3.9	-0.4	1.9	-0.2	0.2
Prostate Cancer	1.1	1.6	5.9	0.4	1.0	1.4	0.6	0.3	2.4	1.2	1.4
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	3.0	-1.7	0.5	1.4	0.3	-1.7	1.2	0.6	1.2
Impedance of leg (right)	1.1	5.4	18.8	0.2	-2.0	-0.9	1.0	0.4	-0.7	-4.3	-4.3
Average weekly fortified wine intake	1.1	1.3	2.6	0.9	-0.3	-1.6	-0.1	0.7	-1.0	-1.6	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	4.5	2.1	-1.0	-0.9	1.0	2.0	-0.7	-0.9	0.8
Breast cancer (self-reported)	1.1	1.3	2.7	-1.4	0.9	1.3	-0.7	-1.3	1.6	0.8	0.6
Schizophrenia (2014)	1.0	2.3	6.4	-2.5	0.5	2.1	0.4	-2.5	0.9	0.4	0.5
Ulcerative Colitis	1.0	1.4	4.7	0.9	-1.2	-1.2	1.3	0.8	-2.2	-0.6	-0.2
Systolic Blood Pressure	1.0	5.1	13.8	1.6	-1.3	-2.4	0.7	1.8	-0.4	-3.6	-3.7
Ever had hysterectomy (womb removed)	1.0	1.1	3.1	-1.3	0.4	0.5	-0.8	-1.4	-0.1	1.8	1.0
Serious illness, injury or assault to yourself	1.0	1.2	4.3	-0.7	1.0	0.5	-1.1	-0.3	2.1	0.9	1.1
Stomach or abdominal pain in last month	1.0	1.3	2.4	1.2	-1.5	-1.5	0.4	1.5	0.4	-1.2	-0.1
Forced vital capacity (FVC)	1.0	3.7	10.7	-0.1	0.6	0.7	-3.3	-0.8	0.5	2.5	3.3
Falls in the last year	1.0	1.3	5.1	1.0	-2.3	-1.1	-0.6	1.1	-0.2	-1.2	-0.4
Hair/balding pattern: Pattern 3	1.0	1.5	3.8	-1.9	1.2	1.2	-0.0	-1.7	-1.0	0.2	1.5
Number of live births	1.0	1.4	8.1	-0.2	0.6	-0.2	0.4	-0.2	0.2	1.6	2.8
Impedance of arm (left)	1.0	4.5	17.7	1.9	-1.0	-0.7	0.3	2.2	-0.4	-2.9	-4.2
Exposure to tobacco smoke at home	1.0	1.2	3.2	0.1	1.8	1.7	0.6	0.2	1.3	0.8	0.8
Medication: Ventolin 100micrograms inhaler	1.0	1.2	2.9	-1.6	1.3	0.3	-0.1	-1.5	0.4	0.4	1.7
Chronic bronchitis/emphysema (mother)	1.0	1.1	4.4	-1.0	-0.6	1.2	1.0	-0.9	2.1	-0.0	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	1.7	1.2	-1.0	-1.3	-1.0	1.2	-0.4	-1.2	-0.9
Migraine (self-reported)	1.0	1.2	3.2	0.5	-1.5	-1.6	0.3	0.1	-1.8	-1.0	-0.5
Age at last live birth	1.0	1.4	4.5	1.2	-1.3	-0.8	-2.1	1.0	-1.1	-0.1	0.9
Leg pain on walking	1.0	1.3	6.6	-0.5	0.8	0.8	2.6	-0.5	-0.3	0.9	1.0
Commuting to job workplace: Walk	1.0	1.1	4.0	-0.7	1.0	0.8	-0.9	-0.6	2.0	-0.9	1.0
Eye problems/disorders: Cataract	1.0	1.2	6.3	0.7	-0.6	-0.3	-2.5	0.7	-0.2	-1.1	0.7
Medication for cholesterol	1.0	1.5	4.5	-0.2	0.8	1.9	-0.2	-0.5	1.2	2.1	1.4
Average weekly champagne plus white wine intake	1.0	1.4	3.2	-1.2	1.8	1.0	-0.2	-1.2	-1.1	1.1	1.0
Guilty feelings	1.0	1.5	4.6	0.1	1.0	1.2	1.3	-0.1	-0.8	1.6	2.1
Medication: Blood pressure	1.0	1.9	3.5	1.7	-1.2	-1.2	-1.1	1.9	0.2	-1.7	-1.2
Medication: Bendroflumethiazide	1.0	1.6	3.7	1.9	-0.9	-1.1	-1.2	1.8	1.4	-0.2	0.1
Myopia	1.0	1.5	3.6	-1.9	1.2	1.2	-0.4	-1.8	0.2	0.9	1.1
Bipolar Disorder (2011)	0.9	0.9	4.5	-0.6	-2.1	0.1	-0.7	-0.4	0.7	-0.6	0.9
Lung FEV1/FVC ratio	0.9	4.4	14.1	-1.8	-2.3	-0.3	-3.1	-1.5	-0.7	-3.8	-0.3
Chronotype (morning person)	0.9	2.1	6.5	1.5	-2.4	-2.6	0.4	1.4	-0.3	-0.4	-0.1
Average weekly spirits intake	0.9	1.2	5.2	0.2	0.8	1.0	2.3	0.2	-0.0	1.2	1.1
Medication: Simvastatin	0.9	1.3	4.6	0.6	-0.7	-1.6	-0.7	0.7	1.1	-2.1	-0.7
Happiness	0.9	1.1	2.3	1.2	-0.9	-1.0	1.1	1.3	-1.5	-0.4	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	11.0	-1.3	0.4	0.7	-3.3	-1.6	-0.2	1.6	2.3
Peak expiratory flow (PEF)	0.9	2.1	14.0	0.3	-0.5	-0.7	-3.7	0.1	1.0	-1.1	0.1
Blood clot in the leg (DVT)	0.9	1.2	2.1	-1.1	0.3	1.3	-1.5	-1.1	1.1	0.6	1.2
Comparative body size at age 10	0.9	2.4	11.4	-0.6	-0.5	0.2	1.5	-0.9	-1.6	3.4	1.4
Medication: Allopurinol	0.9	1.3	4.2	1.0	0.3	0.4	-0.6	1.0	2.1	-1.1	-1.5
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.1	-1.8	1.0	1.1	-0.5	-1.7	-0.2	-0.3	-0.1
Wears glasses or contact lenses	0.9	1.1	3.1	-1.2	0.3	0.3	0.5	-1.0	1.8	1.5	0.7
Ulcerative Colitis (UC)	0.8	1.4	2.7	0.9	-1.0	-1.6	1.4	0.9	-1.4	-1.2	-0.8
Crohns Disease (2012)	0.8	1.3	2.9	1.3	-0.4	-1.5	0.6	1.1	-1.7	0.0	-1.2
Neuroticism (2016)	0.8	1.1	4.1	2.0	0.6	-0.2	0.4	1.9	-0.6	-0.2	-0.7
Blood White Count	0.8	5.6	19.2	-1.5	-2.8	-0.5	-0.5	-1.3	-4.4	-3.6	0.5
Smoking Status	0.8	1.9	5.5	-1.4	-0.0	2.3	0.7	-1.6	0.7	1.1	1.8
Relative age of first facial hair	0.8	1.6	8.1	0.1	-0.2	1.1	-2.8	-0.0	1.2	0.4	1.4
Vitamin and mineral supplements	0.8	1.0	2.8	-0.8	-1.2	-0.3	1.5	-0.5	-0.4	-1.7	-0.7
Age when periods started (menarche)	0.8	2.0	6.6	-0.1	1.7	1.3	0.7	-0.3	2.6	1.9	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	3.5	-0.6	0.7	0.6	1.9	-0.5	-1.2	0.9	1.8
Pain all over the body in last month	0.8	0.9	3.5	0.1	1.0	-1.1	1.9	0.4	-0.2	0.3	1.0
Impedance of arm (right)	0.8	3.9	18.2	1.0	-0.4	-0.7	0.6	1.3	-0.6	-3.0	-4.3
Forced expiratory volume in 1-second (FEV1)	0.8	2.6	13.7	0.1	-0.1	0.3	-3.7	-0.4	0.3	1.0	2.4
Medication: Cholesterol lowering	0.8	1.2	2.6	1.6	-0.2	-0.8	0.5	1.5	1.4	-1.5	0.3
Pulse wave reflection index	0.8	1.0	4.3	0.9	-0.8	-0.3	-2.1	0.7	-1.0	-0.5	-0.4
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.7	1.4	-0.6	-0.5	1.6	1.3	0.6	0.0	0.7
Had major operations	0.8	0.9	2.5	-0.2	0.7	1.4	-0.9	-0.3	1.6	1.1	0.3
Commuting to job workplace: Car/motor vehicle	0.8	1.0	1.8	0.8	-0.7	-0.9	-0.4	0.9	-1.3	-1.1	-1.3
Smoking status: Previous	0.8	1.3	4.6	-1.2	-1.1	1.2	0.5	-1.1	-0.2	0.1	2.2
Arm fat percentage (left)	0.8	3.1	8.4	2.6	-1.5	-1.6	1.6	2.9	-1.0	-0.3	-1.1
Long-standing illness, disability or infirmity	0.8	1.2	3.6	-1.2	0.7	1.9	0.0	-1.3	0.7	0.7	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	3.8	-1.3	-0.0	0.8	-1.9	-1.4	0.1	1.5	2.0
Alcohol drinker status: Never	0.8	0.9	2.9	-0.5	1.2	0.5	0.7	-0.6	0.9	1.7	0.8
Ever smoked	0.8	1.4	5.8	-0.4	-2.4	-0.1	0.7	-0.4	-1.6	-1.4	0.1
Average weekly beer plus cider intake	0.8	1.1	2.6	1.0	-1.2	-0.8	1.6	1.1	-0.1	-1.2	-0.9
Vascular/heart problems diagnosed by doctor	0.8	2.3	5.2	-1.7	0.9	1.4	0.0	-1.9	-1.8	2.3	0.6
Heart disease (siblings)	0.8	1.0	2.9	-0.5	0.3	0.7	1.7	-0.3	1.5	-0.7	-1.3
Reaction Time	0.7	1.4	3.6	-1.1	1.7	1.1	-1.9	-1.2	-0.4	-0.2	0.8
Number of treatments/medications taken	0.7	1.3	4.0	1.0	-0.6	0.8	-1.2	1.2	1.1	0.3	2.0
Fed-up feelings	0.7	1.2	2.8	1.1	-0.8	0.2	1.1	1.0	1.7	-1.4	0.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.2	-0.2	-1.2	-1.5	0.3	-0.0	-0.9	-1.2	-0.4
Past tobacco smoking	0.7	1.2	3.4	0.9	1.9	-0.9	-0.9	0.9	0.2	0.7	-1.6
Nervous feelings	0.7	1.2	3.7	-0.0	1.4	1.2	-0.7	-0.1	1.4	0.4	1.9
Had menopause	0.7	0.9	1.7	-1.2	0.9	1.3	0.2	-1.1	0.3	0.9	1.0
Qualifications: None of the above	0.7	1.5	4.6	-0.8	-1.7	1.2	1.3	-0.2	2.2	-0.6	-0.7
Medication: Ramipril	0.7	0.9	1.8	1.0	-0.7	-0.8	-0.1	1.2	1.4	-1.3	0.7
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	4.0	-1.9	0.2	0.8	1.0	-2.0	-0.5	0.4	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	2.8	1.7	-0.3	0.0	0.8	1.4	0.9	-0.8	0.8
Neck or shoulder pain in last month	0.7	0.9	2.7	-0.5	-0.6	1.6	-0.2	-0.4	1.1	0.7	1.5
Number of full sisters	0.7	0.8	2.9	-1.0	0.2	0.6	1.7	-0.8	0.9	0.8	0.0
Ever taken oral contraceptive pill	0.7	0.8	1.4	-0.7	-1.0	-0.7	1.0	-0.6	-0.6	-0.9	1.2
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.0	-0.7	0.3	1.2	-0.3	-0.9	-0.3	1.4	1.3
Age started oral contraceptive pill	0.7	0.8	2.8	-0.9	1.1	0.2	1.7	-0.8	-0.9	0.5	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.3	-0.9	-0.2	1.0	-1.5	-0.9	0.9	0.3	1.2
Schizophrenia vs Biploar Disorder	0.6	0.8	2.3	-1.5	0.2	-1.0	0.5	-1.4	-0.8	-0.6	-0.3
Major Depression (MDD)	0.6	0.8	2.2	0.5	-1.0	-0.9	-1.2	0.5	-1.5	-0.5	0.2
Body Mass Index (BMI) (2010)	0.6	0.8	2.1	0.5	-1.5	-1.1	-1.4	0.6	-0.2	0.1	0.1
HDL Cholesterol	0.6	1.0	2.6	-1.2	0.9	1.6	1.2	-1.1	0.3	0.2	-0.7
Systolic blood pressure, automated reading	0.6	1.6	4.4	0.3	-0.4	-1.9	1.5	0.3	0.3	-1.5	-2.1
Medication for hormone replacement therapy	0.6	0.7	1.7	-0.8	-0.6	-1.0	0.7	-0.6	-0.9	-1.3	-0.5
Pack years adult smoking proportion	0.6	0.9	3.5	-0.0	-0.9	0.4	1.9	0.3	0.1	-1.0	-1.2
Chronic bronchitis/emphysema (father)	0.6	0.7	3.1	0.2	0.4	0.2	1.8	0.1	-0.5	0.7	-1.3
Financial difficulties in last 2 years	0.6	0.8	2.7	1.6	-0.0	0.6	-0.3	1.4	0.6	0.3	1.0
Mouth/teeth dental problems	0.6	1.0	2.5	-1.5	0.3	-0.5	-0.5	-1.6	-1.4	0.3	-0.6
Weight	0.6	3.0	11.8	0.3	-0.9	-0.1	-2.8	0.4	1.0	1.6	3.4
Arm fat percentage (right)	0.6	2.4	5.2	2.0	-1.3	-1.5	1.7	2.3	-1.3	-0.6	-1.2
Father’s age at death	0.6	0.8	1.7	-1.1	0.5	1.2	-0.6	-1.3	0.3	-0.8	-0.8
Depression (self-reported)	0.6	0.7	2.3	0.4	-0.8	-0.6	0.2	0.2	-1.5	-0.2	1.4
Medication: Amlodipine	0.6	0.8	1.7	1.3	0.4	0.1	-1.1	1.3	1.2	0.4	0.1
Birth weight	0.6	1.2	3.8	1.0	-1.0	-0.6	1.3	0.8	-1.2	2.0	0.1
Body fat percentage	0.6	2.3	4.9	1.8	-1.9	-1.4	1.2	2.2	-0.5	-1.2	-1.3
Medication: Omeprazole	0.6	0.7	1.9	1.0	-0.8	-0.7	-0.6	1.0	0.4	-1.4	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	3.1	0.6	-0.6	-1.8	-0.6	0.7	0.5	-1.0	-0.2
Supplements: Vitamin C	0.6	0.7	1.8	-1.1	1.1	0.4	0.6	-1.3	0.3	0.6	-0.6
Mood swings	0.6	1.1	3.8	1.2	-0.0	0.7	1.2	1.2	-0.0	-0.0	1.9
Loneliness, isolation	0.6	0.8	2.4	-0.3	-0.3	-1.1	1.5	-0.4	-0.3	-1.6	-0.3
Friendships satisfaction	0.6	0.7	1.5	0.7	-0.5	-0.4	1.2	1.2	0.1	-0.9	-1.1
Qualifications: nursing, teaching	0.6	0.9	2.5	0.9	-0.2	-0.7	-1.0	0.9	-1.1	-0.4	1.6
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.1	1.3	-0.9	-1.4	-0.1	1.3	0.7	-0.7	-0.3
Leg fat percentage (left)	0.6	2.2	4.8	1.4	-2.2	-1.1	2.1	1.7	-0.5	-0.9	-1.1
Fractured/broken bones in last 5 years	0.6	0.7	1.9	-1.4	0.1	0.9	0.1	-1.3	-1.1	0.3	0.2
Commuting to job workplace: Cycle	0.6	0.7	2.3	0.6	-0.9	0.3	-1.5	0.7	0.8	-0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.1	0.9	-0.7	-0.4	-1.2	1.1	0.1	-1.4	-0.1
Basal cell carcinoma (self-reported)	0.6	0.8	2.4	1.6	0.5	-0.3	-1.3	1.2	0.2	0.4	-0.1
Pack years of smoking	0.6	0.8	4.0	-0.4	-0.7	0.8	2.0	-0.1	0.3	-0.9	-0.7
Depressed Affect (Nagel 2018)	0.5	1.1	3.2	0.7	-0.9	0.3	1.8	0.7	0.4	-1.2	1.4
Schizophrenia (2018)	0.5	1.0	2.9	-1.2	0.0	1.7	0.7	-1.3	1.1	0.8	0.1
Coronary Artery Disease (CAD)	0.5	0.6	1.7	0.6	-0.4	-0.5	0.2	0.8	1.3	-1.1	-0.3
Blood Red Count	0.5	4.9	16.2	4.0	-1.5	-1.0	-0.5	4.0	-1.3	0.2	-1.3
Neuroticism	0.5	1.1	2.4	1.5	-1.0	-0.1	1.5	1.4	-0.7	-0.6	0.7
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.7	-0.0	0.3	0.5	0.8	0.0	-0.1	1.2	1.6
Trunk fat percentage	0.5	2.0	4.8	1.7	-1.6	-1.4	0.6	2.2	-0.4	-1.3	-1.1
Hayfever, allergic rhinitis or eczema	0.5	1.0	3.5	-0.9	0.8	0.9	0.0	-1.1	-1.1	0.3	1.9
Medication: Atenolol	0.5	0.6	1.6	0.0	-0.4	-1.0	-1.3	0.2	0.9	-0.9	0.7
Hearing difficulty/problems with background noise	0.5	0.8	1.4	0.9	-1.1	-0.9	-0.7	1.1	-0.4	-0.7	1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.4	0.6	0.5	-0.2	0.1	0.5	-1.6	-0.4	1.0
Medication: Lansoprazole	0.5	0.6	1.9	1.3	-0.4	0.0	-0.8	1.4	0.5	0.3	0.3
Pulse wave Arterial Stiffness index	0.5	0.5	2.3	-0.3	0.0	0.1	-1.0	-0.3	0.8	0.1	1.5
Hair/balding pattern: Pattern 4	0.5	1.1	7.6	-0.1	0.4	0.7	0.3	-0.1	2.8	-0.3	-0.8
Leg fat percentage (right)	0.5	1.8	4.1	1.0	-2.0	-1.1	2.0	1.3	-0.5	-1.2	-1.0
Wheeze or whistling in the chest in last year	0.5	0.8	1.8	-1.0	0.6	0.7	1.2	-1.0	1.3	0.2	0.7
Medication for pain relief, constipation, heartburn	0.5	0.8	3.0	-0.6	0.2	-0.2	-1.7	-0.7	1.3	0.8	0.2
Overall health rating	0.5	1.0	2.5	-0.9	0.7	1.6	0.6	-0.9	1.5	0.3	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.1	0.1	0.5	-0.7	1.8	-0.1	-0.3	0.5	0.5
Knee pain experienced in last month	0.5	0.7	1.6	0.7	-0.2	1.3	0.4	0.6	1.1	1.2	0.8
Back pain experienced in last month	0.5	0.7	1.6	0.3	-1.3	-0.8	-0.3	0.2	-1.2	-0.7	-1.1
Number of self-reported non-cancer illnesses	0.5	0.9	4.0	0.2	0.1	0.4	-0.4	0.4	2.0	0.6	1.4
Mother’s age at death	0.5	0.7	1.9	1.0	-0.6	-0.3	-0.1	1.0	-0.9	-1.4	-0.6
Commuting to job workplace: Public transport	0.5	0.5	1.9	-0.8	-0.7	0.3	-1.4	-0.9	0.5	-0.4	0.3
High cholesterol (Self-reported)	0.5	0.9	3.2	0.7	-0.2	-1.8	1.6	0.7	0.5	-0.2	0.4
Medication: Atorvastatin	0.5	0.6	3.5	0.1	-0.0	-0.1	1.0	0.3	-0.4	0.6	1.9
Illnesses of father: High blood pressure	0.5	0.6	1.6	1.3	-0.2	0.0	0.5	1.1	1.2	0.0	0.4
Irritability	0.5	0.9	1.8	0.8	-1.1	1.1	1.4	0.5	-1.1	-0.6	-0.2
Diastolic blood pressure, automated reading	0.5	1.7	4.2	0.5	-0.2	-2.0	1.8	0.6	-0.7	-1.2	-1.9
Pain experienced in last month	0.5	0.9	1.5	-1.2	0.7	-1.2	-0.5	-1.1	0.1	-0.6	-1.2
Neuroticism (Nagel 2018)	0.4	1.0	3.7	1.2	-0.3	0.4	1.9	1.0	-0.1	-0.7	0.9
Triglycerides	0.4	0.7	1.4	-0.9	0.6	-0.4	-1.2	-0.9	-0.0	-1.1	-1.0
Waist Hip Ratio (WHR)	0.4	1.9	9.1	0.3	0.5	0.2	3.0	0.4	-1.0	-1.3	-1.7
Allergy or Eczema	0.4	1.1	3.4	-0.3	0.3	0.6	-0.5	-0.6	-1.8	0.8	1.8
Heart attack	0.4	0.5	2.7	-0.1	-0.3	-0.6	-0.3	0.2	-0.8	0.0	1.6
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.3	-0.3	1.1	0.1	0.5	-0.3	0.9	0.7	1.1
Fluid intelligence score	0.4	0.8	3.6	-0.9	1.9	0.7	0.9	-0.8	0.6	-0.1	0.2
Hip circumference	0.4	1.5	3.0	1.0	-1.2	-1.6	-1.7	1.2	-0.0	0.1	1.7
Noisy workplace	0.4	0.4	2.0	0.6	-0.5	-1.4	0.6	0.4	0.3	-0.4	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.5	0.4	0.9	0.9	1.2	0.0	-0.6	0.4	0.3
Birth weight of first child	0.4	0.7	1.6	-1.0	0.2	0.1	0.3	-1.2	-1.0	1.3	0.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.0	-0.2	1.4	-0.2	-1.4	-0.2	-0.8	0.1	0.8
Worry too long after embarrassment	0.4	0.6	2.4	-0.6	1.0	-0.0	1.5	-0.7	0.0	-0.1	0.8
Number of children fathered	0.4	0.5	1.2	-1.0	1.1	-0.1	0.7	-1.0	0.4	0.2	-0.2
Age at first live birth	0.4	0.8	2.0	1.1	-0.3	-0.4	-1.1	0.9	-1.4	0.2	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.5	0.5	-0.6	0.1	-1.2	0.8	1.1	-0.3	0.3
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.4	-0.3	-0.9	0.2	-1.2	-0.7	-0.8	-0.7	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.6	-0.4	-0.3	-0.6	1.3	-0.4	-0.3	0.7	1.1
Osteoarthritis (self-reported)	0.4	0.5	3.3	-0.2	-1.8	-0.1	-0.8	-0.4	0.1	-0.3	0.3
Miserableness	0.4	0.7	2.8	-0.1	-1.7	-0.1	0.4	-0.0	-0.0	-1.5	0.5
Hearing aid user	0.4	0.4	2.2	0.2	-1.5	0.7	-0.2	0.1	0.7	-0.1	0.2
Ever depressed for a whole week	0.4	0.5	1.5	0.7	-0.2	-0.7	0.1	0.6	-1.2	-1.1	0.1
Unable to work because of sickness or disability	0.4	0.5	2.2	0.1	-0.9	-0.2	-1.5	0.2	-0.2	-0.9	-0.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.7	-0.0	-0.7	-0.8	-0.3	0.3	-0.8	-0.3	1.3
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.2	0.0	1.5	0.4	1.8	0.1	1.1	0.3	1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.9	-0.6	1.7	0.3	1.4	-0.5	0.5	-0.5	0.2
Primary Biliary Cirrhosis	0.3	0.4	2.0	0.6	0.4	0.3	-0.5	0.6	0.1	-0.0	1.4
Rheumatoid Arthritis	0.3	0.4	1.2	-0.7	0.6	-0.8	-0.0	-0.6	-0.2	-0.2	1.1
Hand grip strength (left)	0.3	0.7	2.0	0.9	-0.5	-1.1	-1.4	0.7	-0.1	-0.1	-0.6
Relative age voice broke	0.3	0.4	1.6	0.3	0.6	0.3	-1.3	0.1	-0.2	1.1	0.2
Body mass index (BMI)	0.3	1.1	2.3	1.3	-0.9	-1.1	1.2	1.5	-0.5	0.7	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.5	-0.1	0.7	1.1	1.2	0.0	0.8	0.4	-1.2
Neuroticism score	0.3	0.6	1.5	0.4	-0.5	0.1	1.2	0.3	-0.7	-0.8	1.2
Time employed in main current job	0.3	0.4	1.2	-0.2	1.1	0.2	-0.9	-0.1	0.2	0.8	0.5
Pulse rate	0.3	0.5	1.8	0.6	-0.2	-0.1	0.6	0.4	0.2	1.0	1.3
Prospective memory result	0.3	0.4	1.0	0.0	-0.2	-0.4	0.8	0.1	0.8	-0.7	1.0
Lung cancer (father)	0.3	0.3	0.9	0.9	0.4	-0.3	-0.4	0.8	0.4	0.5	0.7
Arm fat mass (right)	0.3	1.0	2.4	1.3	-1.0	-1.3	-0.3	1.6	-0.8	0.2	0.8
Headache pain in last month	0.3	0.6	1.2	0.8	-1.0	0.5	0.8	0.7	-1.1	0.1	0.6
Shortness of breath walking on level ground	0.3	0.4	0.9	0.2	-0.9	-1.0	0.2	0.3	-0.1	-0.7	0.7
Qualifications: College or University degree	0.3	1.1	5.7	-0.9	0.4	-0.6	0.2	-1.0	-2.4	-0.6	0.1
Medication: Ibuprofen	0.3	0.4	1.0	0.8	0.2	0.0	1.0	0.5	-0.8	-0.5	-0.1
Whole body fat mass	0.3	1.1	2.8	1.2	-1.7	-1.1	-0.9	1.5	-0.1	-0.3	0.5
Suffer from ‘nerves’	0.3	0.5	1.2	-0.7	1.0	0.4	0.5	-0.7	0.0	0.4	1.1
Arm fat mass (left)	0.3	1.3	3.4	1.7	-1.2	-1.3	-0.4	1.9	-0.6	0.5	0.9
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.0	-0.5	-1.0	0.3	-0.7	-0.4	0.7	-0.3	0.4
LDL Cholesterol	0.2	0.4	2.2	0.5	0.3	0.0	0.5	0.4	1.5	-0.1	-0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.2	0.1	0.6	-0.6	0.4	0.2	0.3	-0.0	1.1
Heel T-Score	0.2	1.8	4.5	1.4	-0.3	0.1	2.1	1.6	-1.5	-0.8	-1.6
BMI	0.2	1.1	3.4	0.3	0.2	0.4	1.1	0.5	1.0	1.6	1.8
Hearing difficulty/problems: Yes	0.2	0.4	2.1	0.4	-0.4	-0.4	-0.2	0.5	-0.2	0.2	1.4
Hand grip strength (right)	0.2	0.5	1.6	-0.1	0.5	0.4	-1.3	-0.3	1.1	0.7	0.6
Townsend deprivation index at recruitment	0.2	0.2	0.7	0.4	0.1	0.3	0.8	0.4	-0.3	-0.6	0.5
Current tobacco smoking	0.2	0.3	1.1	-0.0	-0.3	1.1	0.7	-0.1	0.8	0.5	0.1
Trunk fat mass	0.2	1.0	2.4	1.2	-1.6	-0.9	-0.9	1.5	0.1	-0.4	0.6
Waist circumference	0.2	0.9	2.3	1.2	-1.0	-1.2	0.5	1.5	-0.2	-0.1	0.9
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.4	-0.0	0.7	-1.2	-1.1	0.0	-0.1	-0.7	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.1	0.7	-0.0	0.3	0.1	-0.1	0.4	0.9
Mouth/teeth dental problems: Dentures	0.2	0.4	1.0	0.4	-0.3	0.8	-1.0	0.4	0.5	0.2	0.9
Length of working week for main job	0.2	0.2	0.7	0.5	0.2	0.4	-0.6	0.2	0.3	0.6	0.8
Tense / ‘highly strung’	0.2	0.3	0.5	-0.0	-0.4	0.7	-0.1	-0.3	-0.7	-0.7	0.7
Exposure to tobacco smoke outside home	0.2	0.2	0.7	0.2	0.8	0.2	-0.0	-0.1	0.3	0.1	-0.9
Health satisfaction	0.2	0.3	0.7	0.5	-0.8	-0.1	-0.1	0.8	-0.3	-0.7	-0.3
Heart disease (mother)	0.2	0.2	0.6	0.7	-0.1	0.2	0.4	0.7	-0.4	0.3	0.6
Leg fat mass (right)	0.2	0.7	2.3	0.6	-1.5	-1.0	-0.2	0.8	0.0	-0.3	0.9
Pulse rate, automated reading	0.2	0.6	1.2	1.1	-0.0	-0.2	0.6	0.9	0.8	1.1	0.6
Chest pain or discomfort	0.2	0.3	0.9	0.4	-0.3	0.0	1.0	0.5	-0.0	-0.9	-0.0
Osteoporosis (self-reported)	0.2	0.2	1.2	-0.2	0.4	0.2	-1.1	-0.1	-0.0	0.2	-0.3
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.5	0.6	-0.5	0.3	0.5	0.5	-0.4	0.6	0.7
Risk taking	0.2	0.3	0.9	-0.1	-0.3	0.8	0.8	0.2	0.5	-0.2	1.0
Cholesterol lowering medication	0.2	0.3	0.6	-0.8	0.6	-0.4	0.7	-0.6	-0.1	-0.3	0.5
Leg fat mass (left)	0.2	0.9	2.8	1.0	-1.7	-1.2	-0.3	1.2	-0.0	-0.2	0.8
Worry (Nagel 2018)	0.1	0.2	1.0	0.4	0.1	0.5	0.4	0.2	0.3	0.2	1.0
Breast Cancer	0.1	0.3	0.6	0.5	0.1	0.8	-0.2	0.7	-0.7	0.4	0.4
Hypothyroidism (self reported)	0.1	0.2	0.6	-0.4	-0.7	0.4	0.3	-0.4	-0.8	-0.2	0.1
Tanning	0.1	0.8	1.6	1.0	-0.5	-0.2	-1.2	0.9	-1.2	0.6	0.7
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.5	0.1	-0.3	-0.1	-0.7	0.1	-0.4	-0.7	0.2
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.5	0.1	0.0	0.2	-0.5	-0.0	-0.5	0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.8	-0.1	-0.5	0.5	0.9	0.1	0.3	-0.1	-0.9
Worrier / anxious feelings	0.1	0.2	0.5	0.3	-0.3	0.7	0.2	0.4	0.2	-0.1	0.7
Breastfed as a baby	0.1	0.1	0.4	0.4	0.1	0.6	0.5	0.4	-0.0	0.3	-0.3
Pulse wave peak to peak time	0.1	0.2	1.2	0.1	-0.0	0.1	0.3	0.1	-0.3	0.0	-1.1
Alcohol intake frequency.	0.1	0.3	1.0	0.8	0.2	0.6	0.1	0.7	0.1	1.0	-0.1
Smoking status: Current	0.1	0.2	0.7	-0.2	-0.4	0.9	0.6	-0.3	0.7	-0.0	-0.2
Alcohol drinker status: Previous	0.1	0.2	0.3	0.5	0.6	-0.2	0.2	0.5	0.5	0.2	0.3
Hair Pigment	0.0	0.5	1.7	0.6	0.2	0.8	-1.3	0.8	0.2	0.2	0.8
Family relationship satisfaction	0.0	0.0	0.1	0.1	0.3	-0.2	-0.4	0.3	-0.1	0.0	-0.0

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