Hub : Genes

LYN

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.2592 0.0716 6.9e-05 0.138 NA 0.097 NA 0.126 6.0e-11 NA 4.6e-08 NA 4.5e-10
2 GTEx Brain Cerebellar Hemisphere 0.4490 0.1450 2.4e-03 0.011 NA 0.153 NA 0.116 1.6e-01 NA 9.9e-05 NA 6.7e-04
3 GTEx Brain Cerebellum 0.1980 0.0720 2.8e-03 0.104 NA 0.070 NA 0.166 5.5e-04 NA 4.2e-03 NA 1.2e-05
4 GTEx Cells EBV-transformed lymphocytes 0.3540 0.0960 1.6e-04 0.068 NA 0.166 NA 0.091 3.0e-03 NA 4.5e-06 NA 6.9e-04
5 GTEx Cells Transformed fibroblasts 0.4610 0.0660 5.8e-13 0.327 NA 0.300 NA 0.324 3.7e-25 NA 7.9e-23 NA 6.8e-25
6 GTEx Spleen 0.2460 0.0900 4.2e-03 0.000 NA 0.019 NA 0.013 3.2e-01 NA 1.1e-01 NA 1.5e-01
7 ROSMAP Brain Pre-frontal Cortex 0.0962 0.0272 8.1e-09 0.048 0.078 0.082 0.079 0.090 7.4e-07 2.7e-10 9.8e-11 2.6e-10 1.1e-11
8 TCGA Thyroid Carcinoma 0.0940 0.0350 1.3e-08 0.121 0.095 0.107 NA 0.121 7.7e-12 1.8e-09 1.5e-10 NA 8.3e-12

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 2.1 3.3 8.2 -1.9 1.0 2.9 -0.1 -2.1 0.9 1.6 2.4
Bipolar Disorder or Schizophrenia 1.4 3.3 9.7 -2.2 0.7 3.1 0.5 -2.3 1.4 1.3 1.6
Depressed Affect (Nagel 2018) 0.5 1.1 3.2 0.7 -0.9 0.3 1.8 0.7 0.4 -1.2 1.4
Depression (Nagel 2018) 1.6 2.3 6.0 -0.4 1.6 1.3 2.4 -0.5 0.5 2.0 2.0
Intelligence (Savage-Jansen 2018) 0.3 1.0 3.2 0.0 1.5 0.4 1.8 0.1 1.1 0.3 1.1
Neuroticism (Nagel 2018) 0.4 1.0 3.7 1.2 -0.3 0.4 1.9 1.0 -0.1 -0.7 0.9
Schizophrenia (2018) 0.5 1.0 2.9 -1.2 0.0 1.7 0.7 -1.3 1.1 0.8 0.1
Schizophrenia vs Biploar Disorder 0.6 0.8 2.3 -1.5 0.2 -1.0 0.5 -1.4 -0.8 -0.6 -0.3
Worry (Nagel 2018) 0.1 0.2 1.0 0.4 0.1 0.5 0.4 0.2 0.3 0.2 1.0
Alzheimer’s Disease (in mother) 1.4 1.7 3.6 1.8 0.1 -0.7 1.0 1.9 -0.3 -1.4 -1.7
Alzheimer’s Disease (in father) 1.2 1.3 4.8 0.5 0.5 -0.5 1.2 0.6 -2.2 -0.3 -1.9
Alzheimer’s Disease (including proxy) 2.4 3.5 10.1 2.2 -0.4 -1.0 1.5 2.4 -1.6 -1.0 -3.2
Crohns Disease (2017) 1.8 4.0 11.0 1.8 -1.4 -2.2 1.6 1.8 -3.3 -1.5 -1.6
Irritable Bowel Disease (IBD) 1.7 4.0 7.8 1.9 -1.6 -2.3 1.7 1.8 -2.8 -1.7 -1.8
Ulcerative Colitis (UC) 0.8 1.4 2.7 0.9 -1.0 -1.6 1.4 0.9 -1.4 -1.2 -0.8
Major Depression (MDD) 0.6 0.8 2.2 0.5 -1.0 -0.9 -1.2 0.5 -1.5 -0.5 0.2
Reaction Time 0.7 1.4 3.6 -1.1 1.7 1.1 -1.9 -1.2 -0.4 -0.2 0.8
Verbal and Numeric Reasoning (VNR) 0.3 0.8 2.9 -0.6 1.7 0.3 1.4 -0.5 0.5 -0.5 0.2
Breast Cancer 0.1 0.3 0.6 0.5 0.1 0.8 -0.2 0.7 -0.7 0.4 0.4
Ovarian Cancer 2.0 2.6 5.8 -0.5 2.3 2.2 0.3 -0.4 2.4 1.6 1.2
Prostate Cancer 1.1 1.6 5.9 0.4 1.0 1.4 0.6 0.3 2.4 1.2 1.4
Age at First Birth 1.6 2.4 5.9 -1.0 1.2 1.8 0.1 -1.3 0.7 2.4 2.3
Bipolar Disorder (2011) 0.9 0.9 4.5 -0.6 -2.1 0.1 -0.7 -0.4 0.7 -0.6 0.9
Body Mass Index (BMI) (2010) 0.6 0.8 2.1 0.5 -1.5 -1.1 -1.4 0.6 -0.2 0.1 0.1
Coronary Artery Disease (CAD) 0.5 0.6 1.7 0.6 -0.4 -0.5 0.2 0.8 1.3 -1.1 -0.3
Crohns Disease (2012) 0.8 1.3 2.9 1.3 -0.4 -1.5 0.6 1.1 -1.7 0.0 -1.2
Mean Putamen Volume 1.7 2.0 5.4 0.5 -1.9 -1.3 -1.9 0.6 0.8 -2.3 -0.0
Fasting Glucose 1.4 1.7 3.7 1.2 -1.9 -1.5 -1.3 1.3 0.9 -1.2 -0.5
HbA1C 2.0 2.3 11.4 -0.1 1.0 0.4 -0.7 -0.1 -0.2 2.2 3.4
HDL Cholesterol 0.6 1.0 2.6 -1.2 0.9 1.6 1.2 -1.1 0.3 0.2 -0.7
LDL Cholesterol 0.2 0.4 2.2 0.5 0.3 0.0 0.5 0.4 1.5 -0.1 -0.1
Lupus 2.8 4.3 12.5 -2.3 1.1 2.6 0.3 -2.4 0.4 1.5 3.5
Neuroticism (2016) 0.8 1.1 4.1 2.0 0.6 -0.2 0.4 1.9 -0.6 -0.2 -0.7
Primary Biliary Cirrhosis 0.3 0.4 2.0 0.6 0.4 0.3 -0.5 0.6 0.1 -0.0 1.4
Rheumatoid Arthritis 0.3 0.4 1.2 -0.7 0.6 -0.8 -0.0 -0.6 -0.2 -0.2 1.1
Schizophrenia (2014) 1.0 2.3 6.4 -2.5 0.5 2.1 0.4 -2.5 0.9 0.4 0.5
Triglycerides 0.4 0.7 1.4 -0.9 0.6 -0.4 -1.2 -0.9 -0.0 -1.1 -1.0
Type 2 Diabetes (T2D) (2012) 0.2 0.3 1.2 0.1 0.6 -0.6 0.4 0.2 0.3 -0.0 1.1
Ulcerative Colitis 1.0 1.4 4.7 0.9 -1.2 -1.2 1.3 0.8 -2.2 -0.6 -0.2
Blood Eosinophil Count 1.3 9.8 15.4 -3.6 3.1 3.3 -0.7 -3.6 2.6 3.1 3.9
Blood Platelet Count 2.0 23.7 56.1 4.4 -6.7 -5.1 1.8 4.3 -7.5 -4.7 0.1
Blood Red Count 0.5 4.9 16.2 4.0 -1.5 -1.0 -0.5 4.0 -1.3 0.2 -1.3
Blood White Count 0.8 5.6 19.2 -1.5 -2.8 -0.5 -0.5 -1.3 -4.4 -3.6 0.5
Heel T-Score 0.2 1.8 4.5 1.4 -0.3 0.1 2.1 1.6 -1.5 -0.8 -1.6
BMI 0.2 1.1 3.4 0.3 0.2 0.4 1.1 0.5 1.0 1.6 1.8
Height 2.1 39.8 134.6 -4.3 -1.2 3.2 -11.6 -4.5 3.8 3.9 10.2
Waist Hip Ratio (WHR) 0.4 1.9 9.1 0.3 0.5 0.2 3.0 0.4 -1.0 -1.3 -1.7
Systolic Blood Pressure 1.0 5.1 13.8 1.6 -1.3 -2.4 0.7 1.8 -0.4 -3.6 -3.7
Smoking Status 0.8 1.9 5.5 -1.4 -0.0 2.3 0.7 -1.6 0.7 1.1 1.8
Allergy or Eczema 0.4 1.1 3.4 -0.3 0.3 0.6 -0.5 -0.6 -1.8 0.8 1.8
Cardiovascular Disease 1.3 4.4 10.6 2.0 -0.9 -2.7 0.7 2.5 1.2 -3.2 -2.1
Hypothyroidism (self reported) 0.1 0.2 0.6 -0.4 -0.7 0.4 0.3 -0.4 -0.8 -0.2 0.1
Respiratory disease 2.4 5.3 9.4 -3.1 2.0 1.9 0.7 -3.0 2.5 2.2 2.2
Type 2 Diabetes (T2D) (2018) 2.0 3.8 8.6 -1.9 1.6 2.9 -1.9 -1.5 2.9 -0.2 1.3
Lung FEV1/FVC ratio 0.9 4.4 14.1 -1.8 -2.3 -0.3 -3.1 -1.5 -0.7 -3.8 -0.3
Lung FVC 1.3 6.8 28.2 0.0 2.2 1.4 1.2 -0.7 -1.3 5.3 3.9
Neuroticism 0.5 1.1 2.4 1.5 -1.0 -0.1 1.5 1.4 -0.7 -0.6 0.7
Chronotype (morning person) 0.9 2.1 6.5 1.5 -2.4 -2.6 0.4 1.4 -0.3 -0.4 -0.1
Hair Pigment 0.0 0.5 1.7 0.6 0.2 0.8 -1.3 0.8 0.2 0.2 0.8
Tanning 0.1 0.8 1.6 1.0 -0.5 -0.2 -1.2 0.9 -1.2 0.6 0.7
Hand grip strength (left) 0.3 0.7 2.0 0.9 -0.5 -1.1 -1.4 0.7 -0.1 -0.1 -0.6
Number of treatments/medications taken 0.7 1.3 4.0 1.0 -0.6 0.8 -1.2 1.2 1.1 0.3 2.0
Average weekly spirits intake 0.9 1.2 5.2 0.2 0.8 1.0 2.3 0.2 -0.0 1.2 1.1
Sensitivity / hurt feelings 1.5 2.6 6.2 1.9 -1.4 -1.4 -0.3 1.8 -0.7 -2.5 -1.8
Frequency of depressed mood in last 2 weeks 0.5 0.6 2.7 -0.0 0.3 0.5 0.8 0.0 -0.1 1.2 1.6
Hearing difficulty/problems: Yes 0.2 0.4 2.1 0.4 -0.4 -0.4 -0.2 0.5 -0.2 0.2 1.4
Relative age of first facial hair 0.8 1.6 8.1 0.1 -0.2 1.1 -2.8 -0.0 1.2 0.4 1.4
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 3.0 -1.7 0.5 1.4 0.3 -1.7 1.2 0.6 1.2
Ever used hormone-replacement therapy (HRT) 0.1 0.2 0.5 0.1 -0.3 -0.1 -0.7 0.1 -0.4 -0.7 0.2
Ever had hysterectomy (womb removed) 1.0 1.1 3.1 -1.3 0.4 0.5 -0.8 -1.4 -0.1 1.8 1.0
Systolic blood pressure, automated reading 0.6 1.6 4.4 0.3 -0.4 -1.9 1.5 0.3 0.3 -1.5 -2.1
Eye problems/disorders: Diabetes related eye disease 2.9 3.2 6.4 -2.0 2.3 1.9 0.4 -1.6 0.9 1.7 2.5
Angina 1.6 2.1 6.8 -1.6 0.9 1.3 0.1 -1.6 2.6 0.4 1.6
Medication for hormone replacement therapy 0.6 0.7 1.7 -0.8 -0.6 -1.0 0.7 -0.6 -0.9 -1.3 -0.5
Vitamin and mineral supplements 0.8 1.0 2.8 -0.8 -1.2 -0.3 1.5 -0.5 -0.4 -1.7 -0.7
Supplements: Zinc 1.4 1.5 4.4 -0.0 0.5 1.1 -2.1 -0.1 0.2 1.5 2.0
Medication: Co-codamol 1.4 1.6 2.9 -1.1 -1.4 -1.5 -1.2 -1.0 -1.3 -0.4 1.7
Medication: Metformin 2.2 3.1 10.0 -1.3 1.5 2.1 -0.8 -1.1 3.2 1.1 1.7
Diabetes (father) 1.6 2.0 6.8 -1.8 -1.4 0.6 -2.6 -1.8 -0.3 -0.6 -0.0
Diabetes (mother) 1.5 1.9 3.9 2.0 -1.1 -1.1 -1.6 1.7 0.1 -1.7 -0.8
Severe depression (siblings) 1.3 1.4 2.8 1.6 -1.0 -1.6 1.0 1.7 -1.1 -0.4 -0.4
Pack years adult smoking proportion 0.6 0.9 3.5 -0.0 -0.9 0.4 1.9 0.3 0.1 -1.0 -1.2
Impedance of leg (right) 1.1 5.4 18.8 0.2 -2.0 -0.9 1.0 0.4 -0.7 -4.3 -4.3
Leg fat-free mass (left) 1.4 7.3 24.6 -0.6 0.4 0.6 -4.7 -0.7 1.5 2.8 5.0
Trunk fat percentage 0.5 2.0 4.8 1.7 -1.6 -1.4 0.6 2.2 -0.4 -1.3 -1.1
Hand grip strength (right) 0.2 0.5 1.6 -0.1 0.5 0.4 -1.3 -0.3 1.1 0.7 0.6
Townsend deprivation index at recruitment 0.2 0.2 0.7 0.4 0.1 0.3 0.8 0.4 -0.3 -0.6 0.5
Current tobacco smoking 0.2 0.3 1.1 -0.0 -0.3 1.1 0.7 -0.1 0.8 0.5 0.1
Average weekly fortified wine intake 1.1 1.3 2.6 0.9 -0.3 -1.6 -0.1 0.7 -1.0 -1.6 -1.6
Maternal smoking around birth 1.5 2.2 5.4 0.7 1.3 0.8 2.1 0.7 0.3 2.3 2.1
Fed-up feelings 0.7 1.2 2.8 1.1 -0.8 0.2 1.1 1.0 1.7 -1.4 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 1.6 2.1 5.7 -0.7 1.2 1.5 2.0 -0.8 -0.2 1.6 2.4
Relative age voice broke 0.3 0.4 1.6 0.3 0.6 0.3 -1.3 0.1 -0.2 1.1 0.2
Taking other prescription medications 1.2 1.8 7.7 -0.1 -0.4 1.4 -1.6 0.1 1.3 0.7 2.8
Age when periods started (menarche) 0.8 2.0 6.6 -0.1 1.7 1.3 0.7 -0.3 2.6 1.9 0.8
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.5 0.1 0.0 0.2 -0.5 -0.0 -0.5 0.2 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 0.8 -0.1 -0.5 0.5 0.9 0.1 0.3 -0.1 -0.9
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 2.2 -0.2 -1.2 -1.5 0.3 -0.0 -0.9 -1.2 -0.4
Qualifications: CSEs or equivalent 1.7 2.2 4.5 2.1 -0.6 -0.7 2.0 2.1 -0.2 -0.6 -1.8
Serious illness, injury or assault to yourself 1.0 1.2 4.3 -0.7 1.0 0.5 -1.1 -0.3 2.1 0.9 1.1
High blood pressure 1.2 3.2 6.0 2.3 -1.1 -2.0 0.1 2.4 1.4 -2.4 -1.0
Hayfever, allergic rhinitis or eczema 0.5 1.0 3.5 -0.9 0.8 0.9 0.0 -1.1 -1.1 0.3 1.9
Multivitamins +/- minerals 1.3 1.6 4.3 2.1 -0.3 -1.2 -1.9 1.7 -0.5 0.6 0.2
Stomach or abdominal pain in last month 1.0 1.3 2.4 1.2 -1.5 -1.5 0.4 1.5 0.4 -1.2 -0.1
Supplements: Glucosamine 2.0 2.6 11.5 -1.2 -1.1 -0.1 -3.4 -1.7 -1.8 -0.0 0.8
Diverticular disease/diverticulitis (self-reported) 1.2 1.5 4.9 -1.3 2.2 1.0 1.3 -1.5 -0.4 0.2 -0.1
Medication: Atenolol 0.5 0.6 1.6 0.0 -0.4 -1.0 -1.3 0.2 0.9 -0.9 0.7
Medication: Levothyroxine sodium 1.8 3.0 8.5 -2.9 0.8 1.7 0.4 -2.9 -0.1 1.1 1.4
Sitting height 2.1 14.6 75.9 -1.7 -0.2 1.5 -8.7 -1.7 3.8 -0.0 4.3
Chronic bronchitis/emphysema (father) 0.6 0.7 3.1 0.2 0.4 0.2 1.8 0.1 -0.5 0.7 -1.3
High blood pressure (mother) 3.5 4.9 12.2 2.7 -1.3 -2.1 0.6 2.5 -1.1 -3.5 -2.3
Body mass index (BMI) 0.3 1.1 2.3 1.3 -0.9 -1.1 1.2 1.5 -0.5 0.7 0.5
Impedance of leg (left) 1.3 6.3 21.3 0.6 -2.2 -1.2 0.9 0.9 -0.7 -4.5 -4.6
Leg predicted mass (left) 1.4 7.5 25.4 -0.5 0.5 0.6 -4.7 -0.7 1.5 2.9 5.0
Trunk fat mass 0.2 1.0 2.4 1.2 -1.6 -0.9 -0.9 1.5 0.1 -0.4 0.6
Waist circumference 0.2 0.9 2.3 1.2 -1.0 -1.2 0.5 1.5 -0.2 -0.1 0.9
Number of incorrect matches in round 1.7 2.7 6.3 -2.5 0.0 0.4 -0.1 -2.4 -0.8 2.1 2.2
Past tobacco smoking 0.7 1.2 3.4 0.9 1.9 -0.9 -0.9 0.9 0.2 0.7 -1.6
Alcohol usually taken with meals 1.3 2.1 4.8 -1.5 2.2 2.1 -0.8 -1.6 0.3 1.3 0.8
Nervous feelings 0.7 1.2 3.7 -0.0 1.4 1.2 -0.7 -0.1 1.4 0.4 1.9
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.3 3.5 -0.6 0.7 0.6 1.9 -0.5 -1.2 0.9 1.8
Hearing difficulty/problems with background noise 0.5 0.8 1.4 0.9 -1.1 -0.9 -0.7 1.1 -0.4 -0.7 1.2
Hair/balding pattern: Pattern 2 1.8 2.3 5.1 2.1 -1.5 -0.5 0.5 2.0 1.4 -0.8 -2.3
Had menopause 0.7 0.9 1.7 -1.2 0.9 1.3 0.2 -1.1 0.3 0.9 1.0
Had other major operations 1.2 1.5 5.5 0.7 -1.2 0.3 -2.3 0.6 -0.5 -1.6 -1.1
Forced vital capacity (FVC) 1.0 3.7 10.7 -0.1 0.6 0.7 -3.3 -0.8 0.5 2.5 3.3
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 1.5 -0.1 0.7 1.1 1.2 0.0 0.8 0.4 -1.2
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 2.4 0.6 0.5 -0.2 0.1 0.5 -1.6 -0.4 1.0
Qualifications: None of the above 0.7 1.5 4.6 -0.8 -1.7 1.2 1.3 -0.2 2.2 -0.6 -0.7
Financial difficulties in last 2 years 0.6 0.8 2.7 1.6 -0.0 0.6 -0.3 1.4 0.6 0.3 1.0
Mouth/teeth dental problems 0.6 1.0 2.5 -1.5 0.3 -0.5 -0.5 -1.6 -1.4 0.3 -0.6
Heart attack 0.4 0.5 2.7 -0.1 -0.3 -0.6 -0.3 0.2 -0.8 0.0 1.6
Allergy 1.6 3.7 6.4 2.4 -2.1 -2.1 -0.0 2.5 -1.3 -1.1 -2.5
Pain all over the body in last month 0.8 0.9 3.5 0.1 1.0 -1.1 1.9 0.4 -0.2 0.3 1.0
Diabetes (self-reported) 1.7 2.6 6.9 -0.9 1.6 2.4 -0.8 -0.6 2.6 0.2 1.8
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.3 -0.3 1.1 0.1 0.5 -0.3 0.9 0.7 1.1
Medication: Ramipril 0.7 0.9 1.8 1.0 -0.7 -0.8 -0.1 1.2 1.4 -1.3 0.7
Medication: Simvastatin 0.9 1.3 4.6 0.6 -0.7 -1.6 -0.7 0.7 1.1 -2.1 -0.7
Fluid intelligence score 0.4 0.8 3.6 -0.9 1.9 0.7 0.9 -0.8 0.6 -0.1 0.2
Illnesses of siblings 2.3 3.2 6.5 -2.2 2.3 1.5 0.1 -2.5 0.2 2.1 1.6
Neuroticism score 0.3 0.6 1.5 0.4 -0.5 0.1 1.2 0.3 -0.7 -0.8 1.2
Weight 0.6 3.0 11.8 0.3 -0.9 -0.1 -2.8 0.4 1.0 1.6 3.4
Impedance of arm (right) 0.8 3.9 18.2 1.0 -0.4 -0.7 0.6 1.3 -0.6 -3.0 -4.3
Arm fat percentage (right) 0.6 2.4 5.2 2.0 -1.3 -1.5 1.7 2.3 -1.3 -0.6 -1.2
Trunk fat-free mass 2.5 14.3 48.0 -2.2 0.6 1.8 -5.7 -2.5 2.0 3.9 6.9
Hip circumference 0.4 1.5 3.0 1.0 -1.2 -1.6 -1.7 1.2 -0.0 0.1 1.7
Time employed in main current job 0.3 0.4 1.2 -0.2 1.1 0.2 -0.9 -0.1 0.2 0.8 0.5
Alcohol intake versus 10 years previously 1.4 2.2 5.8 0.5 -2.4 -1.2 -1.7 0.6 -0.9 -2.3 -0.5
Father’s age at death 0.6 0.8 1.7 -1.1 0.5 1.2 -0.6 -1.3 0.3 -0.8 -0.8
Worrier / anxious feelings 0.1 0.2 0.5 0.3 -0.3 0.7 0.2 0.4 0.2 -0.1 0.7
Frequency of tiredness / lethargy in last 2 weeks 1.4 2.2 5.6 2.1 -1.6 -0.3 1.8 2.4 -1.0 -0.8 -0.4
Falls in the last year 1.0 1.3 5.1 1.0 -2.3 -1.1 -0.6 1.1 -0.2 -1.2 -0.4
Hair/balding pattern: Pattern 3 1.0 1.5 3.8 -1.9 1.2 1.2 -0.0 -1.7 -1.0 0.2 1.5
Number of live births 1.0 1.4 8.1 -0.2 0.6 -0.2 0.4 -0.2 0.2 1.6 2.8
Forced expiratory volume in 1-second (FEV1) 0.8 2.6 13.7 0.1 -0.1 0.3 -3.7 -0.4 0.3 1.0 2.4
Pulse rate 0.3 0.5 1.8 0.6 -0.2 -0.1 0.6 0.4 0.2 1.0 1.3
Happiness 0.9 1.1 2.3 1.2 -0.9 -1.0 1.1 1.3 -1.5 -0.4 -0.8
Noisy workplace 0.4 0.4 2.0 0.6 -0.5 -1.4 0.6 0.4 0.3 -0.4 -0.5
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.4 -0.0 0.7 -1.2 -1.1 0.0 -0.1 -0.7 -0.4
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.8 0.1 0.7 -0.0 0.3 0.1 -0.1 0.4 0.9
Mouth/teeth dental problems: Dentures 0.2 0.4 1.0 0.4 -0.3 0.8 -1.0 0.4 0.5 0.2 0.9
Asthma 2.8 5.5 11.3 -2.3 3.4 1.9 0.7 -2.4 2.6 2.6 2.0
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.5 0.4 0.9 0.9 1.2 0.0 -0.6 0.4 0.3
Medication: Cholesterol lowering 0.8 1.2 2.6 1.6 -0.2 -0.8 0.5 1.5 1.4 -1.5 0.3
Depression (self-reported) 0.6 0.7 2.3 0.4 -0.8 -0.6 0.2 0.2 -1.5 -0.2 1.4
Medication: Lansoprazole 0.5 0.6 1.9 1.3 -0.4 0.0 -0.8 1.4 0.5 0.3 0.3
Prospective memory result 0.3 0.4 1.0 0.0 -0.2 -0.4 0.8 0.1 0.8 -0.7 1.0
Lung cancer (father) 0.3 0.3 0.9 0.9 0.4 -0.3 -0.4 0.8 0.4 0.5 0.7
Illnesses of mother 2.4 3.0 6.5 -2.3 1.0 1.5 -0.0 -2.0 0.1 2.5 2.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 3.0 11.0 -1.3 0.4 0.7 -3.3 -1.6 -0.2 1.6 2.3
Pulse wave Arterial Stiffness index 0.5 0.5 2.3 -0.3 0.0 0.1 -1.0 -0.3 0.8 0.1 1.5
Impedance of arm (left) 1.0 4.5 17.7 1.9 -1.0 -0.7 0.3 2.2 -0.4 -2.9 -4.2
Arm fat mass (right) 0.3 1.0 2.4 1.3 -1.0 -1.3 -0.3 1.6 -0.8 0.2 0.8
Trunk predicted mass 2.5 14.4 47.7 -2.3 0.6 1.9 -5.6 -2.6 2.0 4.0 6.9
Standing height 1.9 18.4 82.4 -2.2 -0.4 1.8 -9.1 -2.4 3.0 1.7 6.2
Length of working week for main job 0.2 0.2 0.7 0.5 0.2 0.4 -0.6 0.2 0.3 0.6 0.8
Exposure to tobacco smoke at home 1.0 1.2 3.2 0.1 1.8 1.7 0.6 0.2 1.3 0.8 0.8
Breastfed as a baby 0.1 0.1 0.4 0.4 0.1 0.6 0.5 0.4 -0.0 0.3 -0.3
Tense / ‘highly strung’ 0.2 0.3 0.5 -0.0 -0.4 0.7 -0.1 -0.3 -0.7 -0.7 0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 4.5 2.1 -1.0 -0.9 1.0 2.0 -0.7 -0.9 0.8
Hair/balding pattern: Pattern 4 0.5 1.1 7.6 -0.1 0.4 0.7 0.3 -0.1 2.8 -0.3 -0.8
Birth weight of first child 0.4 0.7 1.6 -1.0 0.2 0.1 0.3 -1.2 -1.0 1.3 0.7
Peak expiratory flow (PEF) 0.9 2.1 14.0 0.3 -0.5 -0.7 -3.7 0.1 1.0 -1.1 0.1
Pulse wave reflection index 0.8 1.0 4.3 0.9 -0.8 -0.3 -2.1 0.7 -1.0 -0.5 -0.4
Ever highly irritable/argumentative for 2 days 1.2 1.5 4.5 0.3 -0.2 0.8 2.0 0.2 0.8 1.4 2.1
Loud music exposure frequency 1.5 1.6 3.9 -1.1 1.6 1.4 -0.3 -1.2 -0.2 1.4 2.0
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 2.0 -0.2 1.4 -0.2 -1.4 -0.2 -0.8 0.1 0.8
Mouth/teeth dental problems: Bleeding gums 1.5 1.9 7.0 1.9 -0.2 -0.9 2.6 1.7 -0.8 -0.4 -0.4
Blood clot in the leg (DVT) 0.9 1.2 2.1 -1.1 0.3 1.3 -1.5 -1.1 1.1 0.6 1.2
Medication: Paracetamol 2.2 3.6 6.8 1.2 -2.5 -0.9 0.2 1.3 -2.5 -2.4 -2.6
Headache pain in last month 0.3 0.6 1.2 0.8 -1.0 0.5 0.8 0.7 -1.1 0.1 0.6
Medication for cholesterol, blood pressure or diabetes 1.7 2.8 5.7 -2.0 1.1 2.0 0.5 -2.1 -1.7 2.4 -0.2
Glaucoma (self-reported) 2.1 2.5 4.9 -2.2 1.6 0.6 1.0 -2.1 2.2 1.2 0.8
Gout (self-reported) 1.3 1.8 5.0 2.2 -0.1 0.2 -0.7 2.2 1.7 -1.0 -0.6
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 4.0 -1.9 0.2 0.8 1.0 -2.0 -0.5 0.4 1.0
Medication: Amlodipine 0.6 0.8 1.7 1.3 0.4 0.1 -1.1 1.3 1.2 0.4 0.1
Medication: Ventolin 100micrograms inhaler 1.0 1.2 2.9 -1.6 1.3 0.3 -0.1 -1.5 0.4 0.4 1.7
Birth weight 0.6 1.2 3.8 1.0 -1.0 -0.6 1.3 0.8 -1.2 2.0 0.1
Chronic bronchitis/emphysema (mother) 1.0 1.1 4.4 -1.0 -0.6 1.2 1.0 -0.9 2.1 -0.0 -0.3
High blood pressure (siblings) 1.8 2.6 6.7 2.5 -1.5 -0.9 -0.5 2.6 0.1 -1.8 -1.1
Forced vital capacity (FVC), Best measure 1.4 5.1 11.1 -1.4 1.3 1.5 -3.1 -1.9 0.4 3.2 3.3
Body fat percentage 0.6 2.3 4.9 1.8 -1.9 -1.4 1.2 2.2 -0.5 -1.2 -1.3
Leg fat percentage (right) 0.5 1.8 4.1 1.0 -2.0 -1.1 2.0 1.3 -0.5 -1.2 -1.0
Arm fat-free mass (right) 1.9 9.5 33.3 -1.4 -0.1 1.0 -5.2 -1.6 1.7 2.7 5.8
Exposure to tobacco smoke outside home 0.2 0.2 0.7 0.2 0.8 0.2 -0.0 -0.1 0.3 0.1 -0.9
Comparative body size at age 10 0.9 2.4 11.4 -0.6 -0.5 0.2 1.5 -0.9 -1.6 3.4 1.4
Number of full brothers 1.5 1.9 7.1 0.2 -2.7 -0.9 0.6 0.3 -1.5 -1.8 -1.0
Worry too long after embarrassment 0.4 0.6 2.4 -0.6 1.0 -0.0 1.5 -0.7 0.0 -0.1 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 1.0 2.8 1.7 -0.3 0.0 0.8 1.4 0.9 -0.8 0.8
Wheeze or whistling in the chest in last year 0.5 0.8 1.8 -1.0 0.6 0.7 1.2 -1.0 1.3 0.2 0.7
Number of children fathered 0.4 0.5 1.2 -1.0 1.1 -0.1 0.7 -1.0 0.4 0.2 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.1 1.7 1.2 -1.0 -1.3 -1.0 1.2 -0.4 -1.2 -0.9
Age at first live birth 0.4 0.8 2.0 1.1 -0.3 -0.4 -1.1 0.9 -1.4 0.2 0.6
Pulse wave peak to peak time 0.1 0.2 1.2 0.1 -0.0 0.1 0.3 0.1 -0.3 0.0 -1.1
Health satisfaction 0.2 0.3 0.7 0.5 -0.8 -0.1 -0.1 0.8 -0.3 -0.7 -0.3
Shortness of breath walking on level ground 0.3 0.4 0.9 0.2 -0.9 -1.0 0.2 0.3 -0.1 -0.7 0.7
Qualifications: College or University degree 0.3 1.1 5.7 -0.9 0.4 -0.6 0.2 -1.0 -2.4 -0.6 0.1
Eye problems/disorders: None of the above 1.5 1.8 3.7 1.0 -1.7 -1.8 0.4 1.0 -1.9 -0.8 -1.3
Mouth/teeth dental problems: Loose teeth 0.8 1.0 2.7 1.4 -0.6 -0.5 1.6 1.3 0.6 0.0 0.7
Emphysema/chronic bronchitis 1.7 1.9 5.0 -2.2 0.1 1.7 0.1 -2.1 1.6 -0.3 0.1
Medication for pain relief, constipation, heartburn 0.5 0.8 3.0 -0.6 0.2 -0.2 -1.7 -0.7 1.3 0.8 0.2
Neck or shoulder pain in last month 0.7 0.9 2.7 -0.5 -0.6 1.6 -0.2 -0.4 1.1 0.7 1.5
Medication: Blood pressure 1.9 3.3 5.5 2.3 -0.7 -2.0 -0.9 2.3 2.3 -2.1 0.7
Angina (self-reported) 1.3 1.7 5.6 -1.2 0.9 1.1 -0.2 -1.2 2.4 0.3 1.7
Migraine (self-reported) 1.0 1.2 3.2 0.5 -1.5 -1.6 0.3 0.1 -1.8 -1.0 -0.5
Medication: Ibuprofen 0.3 0.4 1.0 0.8 0.2 0.0 1.0 0.5 -0.8 -0.5 -0.1
Medication: Allopurinol 0.9 1.3 4.2 1.0 0.3 0.4 -0.6 1.0 2.1 -1.1 -1.5
Medication: Omeprazole 0.6 0.7 1.9 1.0 -0.8 -0.7 -0.6 1.0 0.4 -1.4 0.6
Medication: Seretide 50 evohaler 2.4 2.7 6.8 -1.2 1.9 1.5 0.8 -1.2 2.6 1.6 1.7
Mean time to correctly identify matches 1.5 2.8 6.0 -1.7 1.9 1.6 -1.7 -1.8 0.2 0.8 2.4
Heart disease (mother) 0.2 0.2 0.6 0.7 -0.1 0.2 0.4 0.7 -0.4 0.3 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 3.1 0.6 -0.6 -1.8 -0.6 0.7 0.5 -1.0 -0.2
Whole body fat mass 0.3 1.1 2.8 1.2 -1.7 -1.1 -0.9 1.5 -0.1 -0.3 0.5
Leg fat mass (right) 0.2 0.7 2.3 0.6 -1.5 -1.0 -0.2 0.8 0.0 -0.3 0.9
Arm predicted mass (right) 1.9 9.6 33.7 -1.3 -0.1 1.1 -5.1 -1.5 1.8 3.0 5.8
Pulse rate, automated reading 0.2 0.6 1.2 1.1 -0.0 -0.2 0.6 0.9 0.8 1.1 0.6
Alcohol intake frequency. 0.1 0.3 1.0 0.8 0.2 0.6 0.1 0.7 0.1 1.0 -0.1
Comparative height size at age 10 2.2 11.8 46.8 -1.9 -0.5 0.9 -6.8 -1.9 1.8 1.4 5.9
Number of full sisters 0.7 0.8 2.9 -1.0 0.2 0.6 1.7 -0.8 0.9 0.8 0.0
Suffer from ‘nerves’ 0.3 0.5 1.2 -0.7 1.0 0.4 0.5 -0.7 0.0 0.4 1.1
Overall health rating 0.5 1.0 2.5 -0.9 0.7 1.6 0.6 -0.9 1.5 0.3 0.9
Chest pain or discomfort 0.2 0.3 0.9 0.4 -0.3 0.0 1.0 0.5 -0.0 -0.9 -0.0
Had major operations 0.8 0.9 2.5 -0.2 0.7 1.4 -0.9 -0.3 1.6 1.1 0.3
Age at last live birth 1.0 1.4 4.5 1.2 -1.3 -0.8 -2.1 1.0 -1.1 -0.1 0.9
Family relationship satisfaction 0.0 0.0 0.1 0.1 0.3 -0.2 -0.4 0.3 -0.1 0.0 -0.0
Leg pain on walking 1.0 1.3 6.6 -0.5 0.8 0.8 2.6 -0.5 -0.3 0.9 1.0
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 3.1 0.1 0.5 -0.7 1.8 -0.1 -0.3 0.5 0.5
Commuting to job workplace: Car/motor vehicle 0.8 1.0 1.8 0.8 -0.7 -0.9 -0.4 0.9 -1.3 -1.1 -1.3
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 3.1 -1.8 1.0 1.1 -0.5 -1.7 -0.2 -0.3 -0.1
Medication: Aspirin 2.1 2.7 9.3 -1.4 1.6 1.8 0.1 -1.4 1.5 0.8 3.0
Supplements: Vitamin C 0.6 0.7 1.8 -1.1 1.1 0.4 0.6 -1.3 0.3 0.6 -0.6
Knee pain experienced in last month 0.5 0.7 1.6 0.7 -0.2 1.3 0.4 0.6 1.1 1.2 0.8
Hypertension (Self-reported) 1.6 4.4 8.7 2.8 -1.3 -2.3 0.3 2.9 1.4 -2.8 -1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.5 0.5 -0.6 0.1 -1.2 0.8 1.1 -0.3 0.3
Illnesses of father: Heart disease 1.4 1.9 7.2 2.5 -0.3 -0.8 -0.3 2.7 0.1 0.3 0.8
Illnesses of siblings: Diabetes 3.5 4.3 7.6 2.1 -2.8 -2.4 0.3 2.3 -1.5 -1.9 -2.4
Smoking status: Previous 0.8 1.3 4.6 -1.2 -1.1 1.2 0.5 -1.1 -0.2 0.1 2.2
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.4 15.5 -0.2 -0.1 0.4 -3.9 -0.4 1.9 -0.2 0.2
Whole body fat-free mass 2.0 11.2 38.1 -1.6 0.4 1.3 -5.4 -1.8 1.9 3.4 6.2
Leg fat-free mass (right) 1.3 7.2 24.5 -0.3 0.4 0.4 -4.7 -0.4 1.4 2.8 4.9
Arm fat percentage (left) 0.8 3.1 8.4 2.6 -1.5 -1.6 1.6 2.9 -1.0 -0.3 -1.1
Average weekly red wine intake 1.6 2.4 4.0 -1.3 1.6 2.0 -1.6 -1.3 1.1 1.4 1.8
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.4 -0.3 -0.9 0.2 -1.2 -0.7 -0.8 -0.7 0.3
Mood swings 0.6 1.1 3.8 1.2 -0.0 0.7 1.2 1.2 -0.0 -0.0 1.9
Loneliness, isolation 0.6 0.8 2.4 -0.3 -0.3 -1.1 1.5 -0.4 -0.3 -1.6 -0.3
Long-standing illness, disability or infirmity 0.8 1.2 3.6 -1.2 0.7 1.9 0.0 -1.3 0.7 0.7 1.1
Ever had bowel cancer screening 2.4 2.8 5.7 -1.5 2.4 2.1 -0.8 -1.6 1.8 1.2 1.7
Diabetes diagnosed by doctor 2.9 4.8 9.4 -1.8 2.6 3.0 -0.6 -1.5 3.1 1.3 2.4
Ever had stillbirth, spontaneous miscarriage or termination 2.8 3.0 8.1 2.9 -1.9 -1.0 0.2 2.6 -1.6 -0.3 -1.4
Friendships satisfaction 0.6 0.7 1.5 0.7 -0.5 -0.4 1.2 1.2 0.1 -0.9 -1.1
Qualifications: nursing, teaching 0.6 0.9 2.5 0.9 -0.2 -0.7 -1.0 0.9 -1.1 -0.4 1.6
Commuting to job workplace: Walk 1.0 1.1 4.0 -0.7 1.0 0.8 -0.9 -0.6 2.0 -0.9 1.0
Eye problems/disorders: Cataract 1.0 1.2 6.3 0.7 -0.6 -0.3 -2.5 0.7 -0.2 -1.1 0.7
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 2.1 1.3 -0.9 -1.4 -0.1 1.3 0.7 -0.7 -0.3
Medication for cholesterol 1.0 1.5 4.5 -0.2 0.8 1.9 -0.2 -0.5 1.2 2.1 1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.6 -0.4 -0.3 -0.6 1.3 -0.4 -0.3 0.7 1.1
Back pain experienced in last month 0.5 0.7 1.6 0.3 -1.3 -0.8 -0.3 0.2 -1.2 -0.7 -1.1
Mineral and other dietary supplements 1.4 1.9 4.1 0.8 0.2 -1.3 2.0 1.0 0.4 -2.0 -1.8
Breast cancer (self-reported) 1.1 1.3 2.7 -1.4 0.9 1.3 -0.7 -1.3 1.6 0.8 0.6
Asthma (self-reported) 2.5 4.9 9.6 -2.3 3.1 1.6 1.2 -2.5 2.2 2.4 1.9
Osteoporosis (self-reported) 0.2 0.2 1.2 -0.2 0.4 0.2 -1.1 -0.1 -0.0 0.2 -0.3
Osteoarthritis (self-reported) 0.4 0.5 3.3 -0.2 -1.8 -0.1 -0.8 -0.4 0.1 -0.3 0.3
Medication: Aspirin 1.8 2.3 6.8 -1.4 1.3 1.7 -0.1 -1.3 1.9 0.4 2.6
Medication: Gliclazide 2.2 2.5 4.0 -1.4 1.9 2.0 0.7 -1.4 1.8 1.4 1.5
Illnesses of father: None of the above (group 1) 1.6 2.0 6.2 -2.4 1.4 0.6 -0.9 -2.5 1.0 0.3 0.2
Smoking status: Current 0.1 0.2 0.7 -0.2 -0.4 0.9 0.6 -0.3 0.7 -0.0 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.8 3.8 -1.3 -0.0 0.8 -1.9 -1.4 0.1 1.5 2.0
Whole body water mass 2.0 11.5 38.7 -1.6 0.5 1.3 -5.5 -1.8 1.9 3.5 6.2
Leg predicted mass (right) 1.4 7.3 24.2 -0.3 0.5 0.5 -4.7 -0.5 1.5 2.9 4.9
Arm fat mass (left) 0.3 1.3 3.4 1.7 -1.2 -1.3 -0.4 1.9 -0.6 0.5 0.9
Number of self-reported non-cancer illnesses 0.5 0.9 4.0 0.2 0.1 0.4 -0.4 0.4 2.0 0.6 1.4
Average weekly champagne plus white wine intake 1.0 1.4 3.2 -1.2 1.8 1.0 -0.2 -1.2 -1.1 1.1 1.0
Miserableness 0.4 0.7 2.8 -0.1 -1.7 -0.1 0.4 -0.0 -0.0 -1.5 0.5
Guilty feelings 1.0 1.5 4.6 0.1 1.0 1.2 1.3 -0.1 -0.8 1.6 2.1
Wears glasses or contact lenses 0.9 1.1 3.1 -1.2 0.3 0.3 0.5 -1.0 1.8 1.5 0.7
Ever taken oral contraceptive pill 0.7 0.8 1.4 -0.7 -1.0 -0.7 1.0 -0.6 -0.6 -0.9 1.2
Hearing aid user 0.4 0.4 2.2 0.2 -1.5 0.7 -0.2 0.1 0.7 -0.1 0.2
Mother’s age at death 0.5 0.7 1.9 1.0 -0.6 -0.3 -0.1 1.0 -0.9 -1.4 -0.6
Financial situation satisfaction 2.5 3.1 7.5 1.4 -2.2 -1.4 0.1 1.3 -2.7 -1.5 -2.1
Tinnitus: Yes, now most or all of the time 0.2 0.3 0.5 0.6 -0.5 0.3 0.5 0.5 -0.4 0.6 0.7
Commuting to job workplace: Public transport 0.5 0.5 1.9 -0.8 -0.7 0.3 -1.4 -0.9 0.5 -0.4 0.3
Eye problems/disorders: Glaucoma 1.7 2.0 4.1 -2.0 1.1 1.0 1.3 -1.8 1.8 1.2 0.2
Medication: Blood pressure 1.0 1.9 3.5 1.7 -1.2 -1.2 -1.1 1.9 0.2 -1.7 -1.2
Pain type(s) experienced in last month: Hip pain 0.3 0.3 1.0 -0.5 -1.0 0.3 -0.7 -0.4 0.7 -0.3 0.4
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.0 -0.7 0.3 1.2 -0.3 -0.9 -0.3 1.4 1.3
High cholesterol (Self-reported) 0.5 0.9 3.2 0.7 -0.2 -1.8 1.6 0.7 0.5 -0.2 0.4
Medication: Bendroflumethiazide 1.0 1.6 3.7 1.9 -0.9 -1.1 -1.2 1.8 1.4 -0.2 0.1
Medication: Paracetamol 1.3 2.0 5.6 1.2 -2.4 -0.5 0.6 1.1 -1.6 -1.6 -1.6
Medication: Lisinopril 1.3 1.7 4.9 0.9 -1.3 -2.2 0.0 1.0 0.1 -2.1 -0.9
Medication: Atorvastatin 0.5 0.6 3.5 0.1 -0.0 -0.1 1.0 0.3 -0.4 0.6 1.9
Illnesses of father: High blood pressure 0.5 0.6 1.6 1.3 -0.2 0.0 0.5 1.1 1.2 0.0 0.4
Alcohol drinker status: Never 0.8 0.9 2.9 -0.5 1.2 0.5 0.7 -0.6 0.9 1.7 0.8
Ever smoked 0.8 1.4 5.8 -0.4 -2.4 -0.1 0.7 -0.4 -1.6 -1.4 0.1
Basal metabolic rate 1.6 8.7 30.6 -1.0 0.2 0.8 -4.9 -1.2 1.7 2.9 5.5
Leg fat percentage (left) 0.6 2.2 4.8 1.4 -2.2 -1.1 2.1 1.7 -0.5 -0.9 -1.1
Arm fat-free mass (left) 1.7 8.9 28.9 -1.7 0.4 1.2 -4.9 -2.0 1.6 2.7 5.4
Number of operations (self-reported) 1.6 2.3 5.0 2.1 -1.8 0.1 -2.2 1.8 -0.4 -0.5 -1.4
Average weekly beer plus cider intake 0.8 1.1 2.6 1.0 -1.2 -0.8 1.6 1.1 -0.1 -1.2 -0.9
Irritability 0.5 0.9 1.8 0.8 -1.1 1.1 1.4 0.5 -1.1 -0.6 -0.2
Risk taking 0.2 0.3 0.9 -0.1 -0.3 0.8 0.8 0.2 0.5 -0.2 1.0
Ever had prostate specific antigen (PSA) test 2.1 2.4 4.5 -1.2 1.4 2.1 -0.9 -1.7 0.6 1.8 2.0
Fractured/broken bones in last 5 years 0.6 0.7 1.9 -1.4 0.1 0.9 0.1 -1.3 -1.1 0.3 0.2
Age started oral contraceptive pill 0.7 0.8 2.8 -0.9 1.1 0.2 1.7 -0.8 -0.9 0.5 -0.4
Diastolic blood pressure, automated reading 0.5 1.7 4.2 0.5 -0.2 -2.0 1.8 0.6 -0.7 -1.2 -1.9
Ever depressed for a whole week 0.4 0.5 1.5 0.7 -0.2 -0.7 0.1 0.6 -1.2 -1.1 0.1
Unable to work because of sickness or disability 0.4 0.5 2.2 0.1 -0.9 -0.2 -1.5 0.2 -0.2 -0.9 -0.2
Commuting to job workplace: Cycle 0.6 0.7 2.3 0.6 -0.9 0.3 -1.5 0.7 0.8 -0.7 0.7
Myopia 1.0 1.5 3.6 -1.9 1.2 1.2 -0.4 -1.8 0.2 0.9 1.1
Vascular/heart problems diagnosed by doctor 0.8 2.3 5.2 -1.7 0.9 1.4 0.0 -1.9 -1.8 2.3 0.6
Cholesterol lowering medication 0.2 0.3 0.6 -0.8 0.6 -0.4 0.7 -0.6 -0.1 -0.3 0.5
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 2.1 0.9 -0.7 -0.4 -1.2 1.1 0.1 -1.4 -0.1
Pain experienced in last month 0.5 0.9 1.5 -1.2 0.7 -1.2 -0.5 -1.1 0.1 -0.6 -1.2
Supplements: Calcium 1.6 1.7 2.8 -1.5 1.5 1.0 -1.2 -1.4 0.3 1.7 1.6
Basal cell carcinoma (self-reported) 0.6 0.8 2.4 1.6 0.5 -0.3 -1.3 1.2 0.2 0.4 -0.1
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.7 -0.0 -0.7 -0.8 -0.3 0.3 -0.8 -0.3 1.3
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.3 -0.9 -0.2 1.0 -1.5 -0.9 0.9 0.3 1.2
Heart disease (siblings) 0.8 1.0 2.9 -0.5 0.3 0.7 1.7 -0.3 1.5 -0.7 -1.3
Alcohol drinker status: Previous 0.1 0.2 0.3 0.5 0.6 -0.2 0.2 0.5 0.5 0.2 0.3
Pack years of smoking 0.6 0.8 4.0 -0.4 -0.7 0.8 2.0 -0.1 0.3 -0.9 -0.7
Impedance of whole body 1.3 6.8 27.0 1.2 -1.7 -1.0 0.9 1.6 -0.8 -4.2 -5.2
Leg fat mass (left) 0.2 0.9 2.8 1.0 -1.7 -1.2 -0.3 1.2 -0.0 -0.2 0.8
Arm predicted mass (left) 1.8 8.9 29.3 -1.7 0.5 1.1 -4.8 -1.9 1.5 2.8 5.4