TWAS hub - PENK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1380	0.0380	1.7e-06	0.031	0.068	0.046	0.071	0.052	9.7e-05	9.9e-09	2.3e-06	5.4e-09	6.0e-07
2	ROSMAP	Brain Pre-frontal Cortex	0.1069	0.0294	5.9e-08	0.028	0.058	0.076	0.061	0.057	1.5e-04	5.4e-08	5.1e-10	2.4e-08	6.5e-08
3	TCGA	Bladder Urothelial Carcinoma	0.0270	0.0170	2.8e-03	0.010	0.032	0.027	NA	0.021	4.0e-02	9.1e-04	2.4e-03	NA	5.9e-03
4	TCGA	Breast Invasive Carcinoma	0.0267	0.0138	1.9e-07	0.041	0.043	0.047	NA	0.046	7.0e-09	3.5e-09	6.2e-10	NA	1.0e-09
5	TCGA	Colon Adenocarcinoma	0.1080	0.0530	1.0e-06	0.130	0.133	0.125	NA	0.137	6.3e-08	4.3e-08	1.1e-07	NA	2.6e-08
6	TCGA	Esophageal Carcinoma	0.3520	0.1200	1.5e-10	0.212	0.296	0.328	NA	0.182	2.5e-07	4.8e-10	3.8e-11	NA	2.0e-06
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0692	0.0320	7.5e-10	0.064	0.080	0.080	NA	0.073	1.0e-07	2.6e-09	2.4e-09	NA	1.5e-08
8	TCGA	Pancreatic Adenocarcinoma	0.2270	0.1030	7.0e-09	0.148	0.207	0.203	NA	0.224	8.7e-07	4.3e-09	6.2e-09	NA	8.2e-10
9	TCGA	Prostate Adenocarcinoma	0.0347	0.0213	2.4e-03	0.024	0.023	0.033	NA	0.033	1.5e-03	1.8e-03	1.9e-04	NA	2.0e-04
10	TCGA	Rectum Adenocarcinoma	0.1780	0.1000	8.3e-03	0.111	0.066	0.032	NA	0.093	1.5e-03	1.2e-02	6.0e-02	NA	3.4e-03
11	TCGA	Stomach Adenocarcinoma	0.0690	0.0310	2.2e-05	0.080	0.055	0.056	NA	0.064	2.2e-06	8.3e-05	6.4e-05	NA	2.0e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Supplements: Glucosamine	12.0	15.6	23.8	0.1	0.7	-4.8	-4.3	-4.5	-4.9	-4.8	-4.6	-1.2	-4.4	-4.6
Sitting height	7.3	52.0	88.9	0.0	-3.0	-8.9	-9.4	-7.2	-8.9	-8.2	-9.1	-6.0	-6.3	-6.1
Standing height	5.6	55.2	85.1	0.4	-1.5	-9.1	-9.2	-8.1	-9.1	-8.7	-9.2	-4.8	-7.4	-7.2
Had other major operations	5.3	6.5	9.8	1.4	0.2	-3.0	-2.8	-2.9	-3.1	-3.1	-3.0	-0.4	-2.8	-2.8
Mouth/teeth dental problems: Loose teeth	5.3	6.3	10.0	-0.6	-0.6	2.9	2.9	3.2	3.0	2.7	2.8	0.7	3.1	2.6
Loneliness, isolation	5.3	7.3	11.4	-0.7	-0.3	3.4	3.1	3.2	3.0	3.2	3.1	1.4	3.0	2.8
Multivitamins +/- minerals	5.2	6.6	9.8	0.6	0.2	-3.1	-3.1	-3.1	-2.7	-2.9	-3.0	-1.7	-3.0	-2.6
Peak expiratory flow (PEF)	5.2	12.0	18.0	-1.0	-1.0	-4.2	-4.1	-3.9	-4.1	-4.1	-4.1	-2.2	-3.7	-3.4
Qualifications: None of the above	5.1	10.9	17.7	1.4	-0.3	4.0	4.1	3.8	3.8	3.8	4.2	1.4	3.5	3.2
Height	4.8	92.3	139.2	0.1	-2.1	-11.7	-11.7	-10.5	-11.8	-11.4	-11.7	-5.7	-9.7	-9.7
Supplements: Zinc	4.7	5.1	7.7	0.0	0.6	-2.7	-2.6	-2.8	-2.5	-2.6	-2.8	-0.5	-2.7	-2.5
Current tobacco smoking	4.6	7.6	11.5	0.4	0.3	3.4	3.4	3.3	3.0	3.2	3.4	1.2	3.1	2.8
Forced expiratory volume in 1-second (FEV1), Best measure	4.6	14.8	22.6	0.2	1.0	-4.6	-4.2	-4.6	-4.4	-4.5	-4.7	-0.4	-4.4	-4.5
Supplements: Fish oil (including cod liver oil)	4.6	6.0	9.0	0.5	1.5	-3.0	-2.5	-2.8	-2.7	-3.0	-2.9	-0.6	-2.7	-2.9
Comparative height size at age 10	4.5	24.9	39.6	-0.8	-2.0	-6.1	-6.1	-5.1	-6.3	-5.9	-6.0	-3.9	-4.6	-4.6
Trunk fat-free mass	4.3	24.7	36.6	0.1	-0.8	-6.0	-5.7	-6.0	-5.7	-6.0	-5.7	-1.9	-5.8	-5.3
Trunk predicted mass	4.3	24.8	36.8	0.1	-0.8	-6.1	-5.7	-6.0	-5.7	-6.0	-5.7	-2.0	-5.8	-5.3
Mineral and other dietary supplements	4.3	5.8	8.8	-0.2	-1.3	3.0	2.4	2.7	2.8	2.9	2.7	0.7	2.7	2.9
Smoking status: Current	4.3	6.9	10.3	0.7	0.4	3.2	3.2	3.1	3.0	3.0	3.2	1.1	2.9	2.7
Ever highly irritable/argumentative for 2 days	4.1	5.0	7.6	-1.1	-1.2	2.7	2.7	2.6	2.2	2.5	2.8	0.9	2.4	2.2
Alcohol intake versus 10 years previously	4.0	6.0	9.2	0.3	-0.7	-3.0	-2.8	-2.8	-3.0	-3.0	-2.6	-1.3	-2.7	-2.5
Forced vital capacity (FVC), Best measure	4.0	14.6	23.3	0.5	1.2	-4.5	-4.2	-4.5	-4.3	-4.5	-4.8	-0.2	-4.3	-4.4
Wheeze or whistling in the chest in last year	4.0	7.1	11.9	-0.8	-1.0	3.4	3.2	2.8	3.1	3.1	3.5	0.8	2.6	2.8
Vitamin and mineral supplements	3.7	5.0	8.0	-0.5	-0.2	2.8	2.7	2.6	2.2	2.5	2.8	1.6	2.4	2.2
Frequency of tenseness / restlessness in last 2 weeks	3.7	5.7	9.8	-0.5	1.5	2.9	3.1	2.0	2.9	2.7	3.1	2.5	1.7	1.9
Forced expiratory volume in 1-second (FEV1)	3.7	12.4	18.2	0.0	0.8	-4.2	-3.9	-4.2	-4.1	-4.1	-4.3	-0.8	-4.1	-4.0
Frequency of unenthusiasm / disinterest in last 2 weeks	3.6	4.9	8.4	-1.7	-0.3	2.9	2.5	2.2	2.4	2.7	2.7	1.5	2.0	2.2
Fed-up feelings	3.4	6.2	9.6	-0.8	-1.1	3.1	2.6	2.9	2.6	3.1	2.9	0.3	2.9	2.9
Number of full brothers	3.4	4.3	8.1	0.1	-0.8	-2.2	-1.8	-2.5	-2.3	-2.6	-2.2	0.8	-2.6	-2.9
Whole body water mass	3.4	19.5	28.7	0.2	-0.8	-5.3	-5.1	-5.3	-5.2	-5.4	-5.0	-1.6	-5.1	-4.7
Whole body fat-free mass	3.3	18.9	28.0	0.1	-0.8	-5.3	-5.0	-5.3	-5.1	-5.3	-4.9	-1.6	-5.1	-4.6
Happiness	3.2	3.9	7.0	0.3	0.7	2.5	2.6	1.6	2.6	2.3	2.5	1.9	1.3	1.6
Arm fat-free mass (right)	3.2	16.3	24.3	0.3	-0.7	-4.9	-4.6	-4.9	-4.7	-4.9	-4.5	-1.5	-4.7	-4.3
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.4	11.1	2.8	3.3	-0.0	0.8	-1.2	0.1	-0.5	0.1	3.2	-1.6	-1.7
Arm fat-free mass (left)	3.1	15.8	23.6	0.4	-0.7	-4.8	-4.5	-4.8	-4.7	-4.9	-4.4	-1.3	-4.7	-4.3
Fractured/broken bones in last 5 years	3.1	3.9	8.3	1.0	1.1	-1.9	-1.7	-2.8	-1.7	-2.2	-1.9	1.2	-2.9	-2.4
Arm predicted mass (left)	3.1	15.9	23.7	0.3	-0.6	-4.8	-4.5	-4.8	-4.7	-4.9	-4.4	-1.3	-4.7	-4.3
Stomach or abdominal pain in last month	3.0	3.7	8.4	-1.1	-1.2	1.9	1.1	2.3	2.0	2.3	1.7	-1.4	2.5	2.9
Hair/balding pattern: Pattern 2	3.0	3.8	7.4	-0.2	-1.4	1.8	1.2	2.5	1.5	2.1	1.8	-2.2	2.7	2.7
Arm predicted mass (right)	3.0	15.6	23.1	0.2	-0.7	-4.8	-4.5	-4.8	-4.6	-4.8	-4.4	-1.4	-4.7	-4.2
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.0	11.7	0.2	-0.9	-2.9	-3.4	-2.5	-3.1	-2.7	-3.0	-2.2	-2.2	-1.8
LDL Cholesterol	2.8	4.4	8.0	-0.7	-1.2	2.2	1.9	2.7	2.1	2.4	2.0	-0.7	2.8	2.7
Qualifications: O levels/GCSEs or equivalent	2.8	4.4	7.0	-1.0	-0.5	-2.6	-2.6	-2.4	-2.3	-2.3	-2.7	-1.2	-2.2	-2.1
Illnesses of father: High blood pressure	2.8	3.4	6.0	0.4	0.1	2.3	2.2	1.9	2.4	2.2	2.3	0.3	1.8	2.2
Systolic blood pressure, automated reading	2.6	7.6	13.5	-1.0	-1.3	2.9	2.6	3.6	2.9	3.1	2.9	-0.6	3.7	3.4
Pack years adult smoking proportion	2.6	4.0	7.8	1.3	0.8	2.5	2.8	1.8	2.2	2.2	2.4	2.2	1.4	1.3
Alcohol usually taken with meals	2.6	4.3	8.1	-0.0	0.3	-2.6	-2.8	-2.3	-2.3	-2.3	-2.8	-0.7	-2.1	-1.8
Leg fat-free mass (right)	2.6	13.9	20.2	0.1	-0.8	-4.5	-4.3	-4.5	-4.4	-4.5	-4.2	-1.4	-4.3	-3.9
Leg predicted mass (right)	2.6	13.7	20.0	0.1	-0.8	-4.5	-4.3	-4.4	-4.4	-4.5	-4.2	-1.4	-4.3	-3.8
Basal metabolic rate	2.6	14.6	21.7	0.2	-0.7	-4.6	-4.2	-4.7	-4.5	-4.7	-4.2	-1.3	-4.5	-4.1
Number of operations (self-reported)	2.6	3.9	6.1	2.1	0.4	-2.2	-2.2	-1.9	-2.4	-2.3	-2.5	-0.7	-1.7	-2.0
Forced vital capacity (FVC)	2.5	9.6	14.4	0.9	1.5	-3.6	-3.3	-3.7	-3.4	-3.6	-3.8	-0.1	-3.6	-3.6
Bilateral oophorectomy (both ovaries removed)	2.4	2.7	8.3	2.9	2.7	-1.2	-0.7	-1.6	-1.0	-1.3	-0.9	0.9	-1.8	-1.6
Medication: Ramipril	2.4	3.1	4.9	1.3	0.4	2.1	2.0	1.8	2.2	2.0	2.2	0.5	1.6	2.0
Worry too long after embarrassment	2.4	4.0	6.5	-0.6	0.4	2.5	2.5	2.0	2.4	2.2	2.3	2.2	1.8	1.6
Pack years of smoking	2.4	3.5	6.6	1.5	1.0	2.3	2.6	1.6	2.0	2.0	2.2	2.1	1.4	1.2
Breastfed as a baby	2.2	2.7	5.1	0.5	-0.4	2.0	2.0	1.6	2.2	1.9	2.1	1.1	1.5	1.5
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.7	5.7	-0.8	0.5	2.0	2.4	1.5	1.6	1.7	2.3	1.7	1.3	1.1
Depression (Nagel 2018)	2.1	3.2	5.3	-0.5	0.8	2.3	2.0	2.0	2.1	2.2	2.1	0.8	2.0	1.8
Prostate Cancer	2.1	2.9	4.8	-0.3	0.1	2.0	1.7	2.1	2.0	2.2	1.8	0.4	2.1	2.2
Smoking Status	2.1	5.1	9.6	1.2	0.5	2.8	3.1	2.2	2.7	2.3	3.1	2.1	1.8	1.6
Leg fat-free mass (left)	2.1	11.4	17.2	0.3	-0.3	-4.0	-3.7	-4.1	-4.0	-4.1	-3.7	-1.0	-4.0	-3.7
Leg predicted mass (left)	2.1	11.2	16.9	0.3	-0.3	-4.0	-3.7	-4.1	-4.0	-4.1	-3.7	-0.9	-4.0	-3.6
Allergy or Eczema	2.0	5.4	9.3	2.4	2.2	-2.1	-1.4	-2.7	-2.2	-2.5	-1.8	1.7	-2.9	-3.0
Diastolic blood pressure, automated reading	2.0	6.1	9.3	0.4	0.1	2.9	3.0	2.9	3.0	3.0	3.0	0.7	2.7	2.7
Relative age voice broke	1.9	2.9	4.5	0.3	1.0	-2.1	-1.8	-1.9	-1.8	-2.0	-2.1	-0.4	-1.9	-2.1
Mouth/teeth dental problems	1.9	3.0	5.6	1.2	0.8	-1.8	-1.8	-2.3	-1.9	-1.8	-1.7	-0.1	-2.4	-1.9
Illnesses of mother	1.9	2.3	4.0	0.1	-1.6	-1.7	-1.5	-2.0	-1.0	-1.8	-1.6	-0.2	-2.0	-1.7
Suffer from ‘nerves’	1.9	3.0	4.6	1.2	0.8	2.1	1.9	1.9	2.1	2.1	1.9	1.0	1.8	1.9
Chest pain or discomfort	1.9	2.7	5.6	-2.4	-1.1	1.8	1.5	1.8	1.8	1.6	1.5	0.6	1.8	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.8	6.2	-1.2	0.3	-2.3	-2.3	-2.1	-2.3	-2.3	-2.5	-0.7	-2.0	-2.1
Hayfever/allergic rhinitis (self-reported)	1.7	2.2	4.3	0.4	0.2	1.7	1.2	1.9	1.6	1.9	1.4	-0.1	2.0	2.1
Qualifications: A levels/AS levels or equivalent	1.7	3.8	7.6	-0.4	-0.8	-2.3	-2.8	-2.1	-2.2	-2.0	-2.7	-1.5	-1.8	-1.5
Medication: Paracetamol	1.7	2.9	11.6	3.4	2.6	-0.6	0.1	-1.4	-0.5	-0.9	-0.6	2.0	-1.7	-1.7
Medication: Gliclazide	1.7	2.0	3.9	0.4	-0.4	1.6	1.4	1.9	1.1	1.6	1.5	-0.0	2.0	1.7
Alzheimer’s Disease (in mother)	1.6	1.8	4.4	-0.8	0.7	1.6	2.0	1.1	1.1	1.3	1.8	2.1	0.8	0.6
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.5	7.4	0.0	0.9	1.9	2.1	1.2	1.5	1.4	2.0	2.7	0.9	0.7
Hair/balding pattern: Pattern 4	1.6	4.0	8.5	-1.0	-1.5	2.0	1.1	2.7	1.5	2.3	1.5	-1.5	2.9	2.8
Leg fat percentage (right)	1.6	5.7	12.2	0.7	0.7	2.9	3.5	2.4	2.6	2.5	3.4	1.7	2.1	1.9
Age at first live birth	1.6	2.9	5.8	0.2	1.6	-1.8	-1.4	-2.3	-1.4	-1.8	-1.7	0.7	-2.4	-1.9
Qualifications: College or University degree	1.6	4.9	8.7	0.2	0.3	-2.6	-2.7	-2.7	-2.5	-2.4	-2.9	-0.1	-2.6	-2.3
Hair/balding pattern: Pattern 3	1.5	2.2	3.9	-1.1	-1.0	-1.7	-1.3	-1.9	-1.4	-1.7	-1.3	0.2	-2.0	-1.9
Pulse wave reflection index	1.5	1.9	3.4	0.2	0.2	-1.6	-1.3	-1.6	-1.8	-1.8	-1.2	-0.6	-1.6	-1.7
Loud music exposure frequency	1.5	1.6	2.9	-0.9	-0.2	-1.4	-1.3	-1.7	-1.3	-1.5	-1.3	-0.0	-1.7	-1.5
Glaucoma (self-reported)	1.5	1.8	2.8	1.0	-0.0	1.6	1.4	1.4	1.5	1.6	1.5	0.5	1.3	1.7
Leg pain on walking	1.5	1.9	3.1	0.6	-0.0	1.7	1.8	1.5	1.4	1.3	1.5	1.7	1.4	1.0
Irritability	1.5	2.6	5.8	1.1	0.9	-1.4	-1.1	-2.3	-1.0	-1.7	-1.4	1.3	-2.4	-2.2
Depressed Affect (Nagel 2018)	1.4	3.0	5.2	-0.4	-0.4	2.3	2.1	2.0	1.8	2.1	2.2	0.8	1.9	1.7
Type 2 Diabetes (T2D) (2012)	1.4	1.6	5.1	-2.2	-1.8	-0.9	-1.2	-0.7	-1.4	-0.7	-1.0	-1.7	-0.5	-0.1
Cardiovascular Disease	1.4	4.7	8.4	-0.8	-1.1	2.5	1.9	2.8	2.2	2.7	2.1	-0.4	2.9	2.7
Diabetes (father)	1.4	1.7	2.8	-0.0	-0.3	-1.6	-1.4	-1.4	-1.6	-1.7	-1.3	-1.4	-1.3	-1.2
Neuroticism score	1.4	2.8	6.1	0.7	1.3	2.1	2.2	1.0	2.1	1.8	2.0	2.5	0.7	0.9
Medication for cholesterol, blood pressure or diabetes	1.4	2.3	3.6	-1.1	-1.2	-1.7	-1.3	-1.8	-1.6	-1.8	-1.5	0.0	-1.8	-1.9
Eye problems/disorders: Cataract	1.4	1.7	2.7	-0.9	-1.0	-1.6	-1.5	-1.3	-1.4	-1.6	-1.5	-0.5	-1.2	-1.2
Number of self-reported non-cancer illnesses	1.4	2.4	3.9	0.8	-0.0	1.8	1.8	1.9	1.4	1.7	2.0	0.1	1.9	1.6
High cholesterol (Self-reported)	1.4	2.5	4.3	0.1	0.5	1.9	1.5	2.1	1.6	2.0	1.5	0.2	2.1	1.9
Ever smoked	1.4	2.5	4.7	1.4	0.9	1.9	2.2	1.3	1.7	1.5	1.8	2.1	1.1	0.8
Neuroticism (Nagel 2018)	1.3	3.0	5.2	0.5	0.5	2.3	2.1	1.7	2.1	2.1	2.2	1.4	1.5	1.5
Angina	1.3	1.7	5.4	-2.3	-1.6	0.8	0.2	1.4	0.4	0.9	0.6	-1.4	1.6	1.4
Hayfever, allergic rhinitis or eczema	1.3	2.8	5.2	1.6	1.4	-1.4	-0.9	-1.9	-1.6	-1.9	-1.2	1.8	-2.0	-2.3
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	4.1	1.3	1.8	-0.4	-0.1	-1.5	-0.4	-0.8	-0.5	2.0	-1.7	-1.5
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	3.0	0.5	1.7	1.4	1.3	1.3	1.7	1.4	1.0	1.0	1.3	1.2
Number of full sisters	1.3	1.6	3.3	0.4	-0.6	1.5	1.6	1.2	1.7	1.4	1.8	0.5	1.0	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	3.0	-0.6	-0.4	1.5	1.7	1.3	1.4	1.4	1.7	0.9	1.1	1.0
Leg fat percentage (left)	1.3	4.6	9.8	0.5	0.4	2.6	3.1	2.2	2.3	2.3	3.1	1.4	1.9	1.7
Ever had prostate specific antigen (PSA) test	1.3	1.5	7.1	0.5	2.7	-0.7	0.0	-1.0	-1.0	-1.0	-0.5	1.2	-1.2	-1.5
Fasting Glucose	1.2	1.4	4.0	-1.7	-1.7	0.5	-0.1	1.0	0.4	0.9	0.4	-2.0	1.1	1.4
Diverticular disease/diverticulitis (self-reported)	1.2	1.5	2.5	-1.5	-0.4	1.3	1.6	1.0	1.5	1.0	1.4	1.5	0.8	0.6
Father’s age at death	1.2	1.6	2.8	-0.4	-0.3	-1.4	-1.5	-1.5	-1.5	-1.5	-1.7	-0.3	-1.4	-1.4
Number of live births	1.2	1.7	2.5	0.9	0.2	1.4	1.2	1.6	1.5	1.5	1.4	-0.3	1.6	1.5
Qualifications: nursing, teaching	1.2	1.9	4.0	-0.5	-1.5	-1.4	-2.0	-1.6	-1.1	-1.4	-1.7	-0.7	-1.5	-0.7
Financial situation satisfaction	1.2	1.5	7.3	1.3	1.4	0.5	1.2	-0.7	0.6	-0.0	0.9	2.7	-1.1	-1.0
Mean Putamen Volume	1.1	1.3	6.1	0.4	-2.5	-0.8	-1.3	-0.7	-0.8	-0.7	-0.8	-1.9	-0.5	0.1
Systolic Blood Pressure	1.1	5.5	7.9	-2.5	-2.5	2.3	1.9	2.7	2.3	2.6	2.1	-0.4	2.8	2.8
Average weekly spirits intake	1.1	1.4	3.1	-1.0	0.4	1.3	1.7	0.9	1.3	1.1	1.3	1.8	0.7	0.3
Medication: Atenolol	1.1	1.4	2.4	-0.6	-0.3	1.2	1.1	1.5	1.1	1.4	1.3	-0.4	1.5	1.6
Past tobacco smoking	1.1	2.0	3.7	-1.9	-0.7	-1.6	-1.8	-1.0	-1.6	-1.2	-1.7	-1.8	-0.8	-0.7
Nervous feelings	1.1	2.0	3.4	-0.8	-0.4	1.8	1.4	1.5	1.6	1.8	1.6	0.0	1.5	1.9
Pain all over the body in last month	1.1	1.2	2.4	0.3	0.3	1.5	1.6	1.0	1.2	1.0	1.4	1.5	0.8	0.4
Arm fat percentage (right)	1.1	4.4	10.2	1.1	1.2	2.5	3.2	1.6	2.2	2.0	2.9	2.7	1.2	1.1
Noisy workplace	1.1	1.4	3.1	-0.5	-1.6	0.9	0.5	1.6	0.7	1.1	0.7	-1.1	1.8	1.6
Prospective memory result	1.1	1.3	2.3	0.4	0.3	1.4	1.5	1.3	1.5	1.3	1.5	0.4	1.1	1.0
Exposure to tobacco smoke at home	1.1	1.2	1.9	-0.2	-1.0	1.3	1.2	1.4	1.0	1.2	1.3	-0.0	1.4	1.3
Body fat percentage	1.1	4.3	9.0	1.1	0.6	2.5	3.0	2.1	2.1	2.1	2.9	1.7	1.8	1.6
Angina (self-reported)	1.1	1.4	6.1	-2.5	-1.5	0.5	-0.0	1.1	0.2	0.7	0.4	-1.5	1.3	1.2
Mood swings	1.1	2.1	3.8	-0.8	0.3	1.8	2.0	1.3	1.4	1.6	1.9	1.4	1.1	1.2
Eye problems/disorders: Glaucoma	1.1	1.3	2.5	0.9	-0.4	1.3	0.9	1.3	1.3	1.3	1.1	0.1	1.4	1.6
Medication: Bendroflumethiazide	1.1	1.7	3.1	-0.9	-0.3	1.4	1.2	1.7	0.9	1.6	1.3	-0.4	1.8	1.6
Commuting to job workplace: Cycle	1.1	1.3	4.1	-2.0	-1.7	-1.0	-1.4	-0.7	-0.7	-0.7	-1.3	-1.1	-0.5	-0.3
Vascular/heart problems diagnosed by doctor	1.1	2.9	5.7	0.7	1.6	-1.6	-1.1	-2.2	-1.4	-1.8	-1.4	1.4	-2.4	-2.3
Neuroticism	1.0	2.4	5.5	1.4	1.4	1.8	1.8	0.8	1.8	1.5	1.7	2.4	0.5	0.8
Relative age of first facial hair	1.0	2.1	3.3	1.4	0.9	-1.8	-1.7	-1.2	-1.4	-1.7	-1.8	-1.4	-1.1	-1.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	3.5	1.9	1.0	-1.0	-0.8	-0.9	-0.9	-1.0	-0.8	-0.2	-0.9	-1.1
High blood pressure	1.0	2.9	5.5	-0.2	-0.9	1.7	1.3	2.2	1.6	2.0	1.6	-1.1	2.3	2.3
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.4	-0.6	-1.3	0.9	0.2	1.2	0.8	1.1	0.5	-1.1	1.4	1.6
Health satisfaction	1.0	1.4	3.2	1.4	1.8	1.0	1.4	0.2	1.3	0.8	1.5	1.5	-0.1	0.2
Medication for pain relief, constipation, heartburn	1.0	1.7	10.0	-3.2	-1.6	-0.4	-0.8	0.4	-0.6	0.0	-0.5	-1.9	0.7	0.6
Hypertension (Self-reported)	1.0	2.8	5.2	0.0	-0.6	1.8	1.4	2.2	1.6	2.0	1.6	-1.0	2.3	2.2
Arm fat percentage (left)	1.0	4.0	9.0	0.7	1.0	2.5	3.0	1.7	2.1	2.0	2.8	2.2	1.4	1.2
Friendships satisfaction	1.0	1.2	2.9	-0.3	-0.8	1.2	0.8	1.1	1.3	1.4	1.1	-0.4	1.1	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.1	-0.2	-0.7	1.1	0.8	1.4	1.2	1.1	1.0	-0.9	1.5	1.4
Alzheimer’s Disease (including proxy)	0.9	1.4	6.3	-0.2	0.6	1.2	1.8	0.6	0.7	0.7	1.4	2.5	0.3	-0.2
Breast Cancer	0.9	2.1	3.7	-0.7	-1.5	-1.7	-1.8	-1.4	-1.7	-1.6	-1.9	-0.8	-1.2	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	3.8	0.4	0.4	1.7	1.8	1.5	1.7	1.7	2.0	0.7	1.4	1.5
Medication: Levothyroxine sodium	0.9	1.6	3.4	0.1	0.3	1.6	1.5	1.2	1.6	1.4	1.3	1.8	1.0	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	3.6	-0.2	-0.1	1.7	1.8	1.5	1.6	1.7	1.9	0.8	1.4	1.4
Falls in the last year	0.9	1.3	2.6	0.0	-0.4	1.4	1.6	1.4	1.0	1.2	1.6	0.4	1.2	1.0
Medication: Cholesterol lowering	0.9	1.4	2.3	0.5	1.1	1.4	1.0	1.3	1.3	1.5	1.0	0.4	1.3	1.5
High blood pressure (siblings)	0.9	1.3	4.4	1.3	2.1	-1.1	-0.9	-1.1	-0.9	-1.0	-1.1	-0.3	-1.1	-1.0
Back pain experienced in last month	0.9	1.3	2.2	0.1	-0.2	1.4	1.5	1.3	1.3	1.3	1.5	0.4	1.2	1.2
Medication: Blood pressure	0.9	1.6	3.7	-1.7	-1.9	0.9	1.0	1.5	0.6	1.0	1.1	-0.6	1.6	1.2
Worry (Nagel 2018)	0.8	1.7	2.6	1.2	1.5	1.6	1.4	0.9	1.6	1.6	1.4	1.2	0.8	1.1
Crohns Disease (2017)	0.8	1.8	4.4	0.7	2.1	-0.9	-0.5	-1.5	-1.2	-1.2	-0.8	1.7	-1.6	-1.6
Major Depression (MDD)	0.8	1.0	2.4	1.5	1.5	-0.5	0.1	-1.1	-0.5	-0.7	-0.1	0.8	-1.3	-1.2
Coronary Artery Disease (CAD)	0.8	1.0	2.0	0.8	-0.1	1.0	0.7	1.2	1.1	1.1	0.6	-0.6	1.3	1.4
HDL Cholesterol	0.8	1.3	3.1	-1.2	-1.3	-1.1	-1.8	-0.9	-1.3	-0.9	-1.5	-1.1	-0.7	-0.1
Primary Biliary Cirrhosis	0.8	1.1	1.9	-1.4	0.3	-1.0	-1.2	-1.1	-1.2	-1.2	-1.1	-0.2	-1.1	-1.1
Blood Platelet Count	0.8	9.5	26.0	1.5	3.8	3.4	4.0	1.8	3.0	2.8	3.3	5.1	1.2	1.1
BMI	0.8	4.6	10.1	0.2	0.9	2.6	3.2	1.8	2.4	2.2	3.0	2.3	1.4	1.4
Frequency of depressed mood in last 2 weeks	0.8	1.2	2.1	-1.5	0.1	1.4	1.1	0.8	1.2	1.3	1.3	0.4	0.7	1.1
Maternal smoking around birth	0.8	1.1	2.5	1.4	1.6	1.0	1.3	0.4	0.9	0.7	1.1	1.4	0.2	-0.0
Weight	0.8	3.8	6.1	0.4	-0.2	-2.3	-1.8	-2.4	-2.5	-2.4	-1.9	-0.3	-2.5	-2.3
Time employed in main current job	0.8	0.9	3.6	-0.0	-0.0	-1.2	-0.9	-0.4	-1.2	-1.1	-0.9	-1.9	-0.2	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	1.8	0.7	0.6	1.4	1.3	1.1	1.3	1.2	1.3	0.9	1.0	1.2
Medication: Blood pressure	0.8	1.4	2.6	1.1	0.7	1.1	0.7	1.5	1.1	1.2	1.1	-1.1	1.6	1.6
Medication: Seretide 50 evohaler	0.8	0.9	2.2	-0.3	-1.4	0.7	0.5	0.8	0.8	0.8	0.9	-1.5	0.9	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.7	-0.0	-0.5	1.0	1.2	1.2	1.0	1.1	1.3	-0.1	1.1	1.2
Had major operations	0.8	1.0	4.8	-0.6	-2.2	0.0	-0.5	0.8	-0.1	0.2	-0.3	-1.4	1.1	1.0
Age at last live birth	0.8	1.2	2.6	0.6	0.7	-1.1	-1.0	-1.6	-0.8	-1.2	-1.1	0.6	-1.6	-1.1
Guilty feelings	0.8	1.2	2.5	0.5	1.3	1.2	1.3	0.8	1.2	1.0	1.3	1.6	0.6	0.7
Commuting to job workplace: Public transport	0.8	1.0	3.6	1.9	0.9	-0.9	-0.8	-1.0	-0.8	-0.9	-0.9	-0.4	-0.9	-0.9
Alcohol drinker status: Never	0.8	0.9	1.9	-0.2	0.1	1.3	1.4	0.8	1.4	1.1	1.3	0.8	0.6	0.5
Neuroticism (2016)	0.7	1.1	2.0	0.8	0.9	1.3	1.1	0.6	1.4	1.3	1.2	1.0	0.5	1.0
Triglycerides	0.7	1.1	2.8	-1.3	-1.6	-1.0	-1.1	-0.2	-1.1	-0.8	-1.1	-1.7	-0.0	-0.4
Hand grip strength (left)	0.7	2.0	3.3	-1.8	-1.6	-1.5	-1.7	-1.3	-1.4	-1.2	-1.5	-1.3	-1.1	-0.8
Trunk fat percentage	0.7	3.0	6.1	1.2	0.5	2.1	2.5	1.8	1.6	1.7	2.4	1.3	1.6	1.3
Average weekly fortified wine intake	0.7	0.8	2.6	0.8	1.6	-0.4	-0.2	-1.2	-0.2	-0.6	-0.4	0.9	-1.4	-1.1
High blood pressure (mother)	0.7	1.0	3.5	1.5	1.9	0.9	1.0	0.6	0.6	0.9	0.9	0.7	0.5	0.6
Length of working week for main job	0.7	0.8	1.2	-0.5	-0.2	1.1	0.8	1.1	1.1	1.1	0.8	0.6	1.1	0.9
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.0	0.1	0.6	1.4	1.4	1.1	1.4	1.3	1.3	1.3	1.0	0.8
Overall health rating	0.7	1.5	2.5	0.7	0.1	1.5	1.4	1.5	1.3	1.3	1.6	0.3	1.4	1.4
Handedness (chirality/laterality): Left-handed	0.7	0.9	5.5	2.4	0.1	-0.2	0.2	-0.4	-0.2	-0.5	-0.3	1.5	-0.6	-0.9
Commuting to job workplace: Walk	0.7	0.8	2.9	-1.1	-1.4	0.3	0.1	0.7	0.2	0.6	0.5	-1.7	0.8	0.9
Medication for cholesterol	0.7	1.0	2.1	1.4	1.1	-0.9	-1.1	-1.2	-0.6	-0.8	-1.2	0.5	-1.2	-0.9
Medication: Paracetamol	0.7	1.1	5.0	2.2	2.0	0.2	0.4	-0.6	0.3	0.1	0.1	1.2	-0.8	-0.5
Reaction Time	0.6	1.1	2.0	0.6	-0.0	-1.2	-1.4	-1.0	-1.4	-1.1	-1.2	-1.2	-0.8	-0.6
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.7	0.0	-0.7	1.0	1.2	1.0	1.1	0.9	1.3	0.1	0.9	0.8
Medication for hormone replacement therapy	0.6	0.7	1.0	-0.3	-0.9	0.9	0.8	1.0	0.5	0.9	0.9	-0.7	1.0	0.9
Medication: Simvastatin	0.6	0.9	1.8	1.2	1.1	0.8	0.4	0.9	0.8	1.0	0.6	-1.3	1.0	1.3
Tense / ‘highly strung’	0.6	0.9	3.9	0.3	0.3	1.1	1.3	0.3	1.3	0.9	0.9	2.0	0.1	0.1
Long-standing illness, disability or infirmity	0.6	0.9	1.6	-0.1	-1.3	1.1	1.0	0.9	0.9	0.9	1.2	0.7	0.9	0.9
Mother’s age at death	0.6	0.7	3.4	1.8	1.6	-0.0	0.2	-0.4	0.2	-0.0	0.1	1.2	-0.5	-0.4
Age started oral contraceptive pill	0.6	0.7	2.4	1.1	1.4	0.7	0.7	0.4	0.7	0.6	0.4	1.5	0.3	0.2
Ever depressed for a whole week	0.6	0.7	2.9	1.2	0.8	-0.1	0.2	-0.7	-0.2	-0.5	-0.2	1.7	-0.8	-1.2
Alzheimer’s Disease (in father)	0.5	0.6	1.7	0.1	0.2	-0.5	-0.1	-0.8	-0.5	-0.8	-0.5	1.3	-0.9	-1.3
Verbal and Numeric Reasoning (VNR)	0.5	1.3	3.2	-1.1	-0.7	-1.2	-1.7	-0.3	-1.2	-0.8	-1.7	-1.8	-0.0	-0.2
Age at First Birth	0.5	0.8	6.4	-2.5	-1.4	0.2	0.1	0.1	0.4	0.1	0.2	0.2	0.1	-0.1
Crohns Disease (2012)	0.5	0.7	1.2	0.8	0.9	-0.9	-0.5	-0.9	-1.0	-0.9	-0.7	0.2	-1.0	-1.1
Ulcerative Colitis	0.5	0.7	2.4	1.2	1.5	0.5	1.0	0.0	0.4	0.3	0.7	1.2	-0.2	-0.2
Waist Hip Ratio (WHR)	0.5	2.4	6.5	-0.9	0.5	1.8	2.2	1.0	1.8	1.6	1.8	2.6	0.7	0.6
Respiratory disease	0.5	1.1	2.6	-1.1	-1.5	0.6	0.4	1.0	0.9	0.9	0.6	-1.6	1.0	1.2
Lung FEV1/FVC ratio	0.5	2.7	4.0	-1.3	-1.3	-1.9	-1.9	-1.6	-2.0	-1.7	-1.9	-0.9	-1.5	-1.7
Lung FVC	0.5	2.5	11.9	1.1	3.4	-0.8	-0.2	-1.1	-0.7	-1.1	-0.8	2.3	-1.3	-1.8
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	0.9	-0.9	-0.7	0.7	0.4	0.9	0.9	0.8	0.6	0.1	0.9	0.9
Medication: Metformin	0.5	0.8	2.3	-0.1	-0.7	0.4	0.0	1.3	0.0	0.5	0.3	-1.5	1.5	1.1
Diabetes (mother)	0.5	0.6	1.6	0.3	-1.0	-0.8	-0.9	-0.2	-1.3	-0.7	-0.9	-1.1	-0.0	-0.3
Body mass index (BMI)	0.5	2.3	5.6	0.0	0.3	1.8	2.4	1.2	1.6	1.4	2.3	1.9	0.9	0.8
Fluid intelligence score	0.5	1.1	2.7	-1.6	-0.7	-1.0	-1.4	-0.4	-1.1	-0.6	-1.4	-1.5	-0.1	-0.2
Illnesses of siblings	0.5	0.8	1.5	-0.2	-0.8	1.0	0.7	1.0	0.9	1.1	0.8	-0.1	1.0	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.1	-1.4	-0.1	0.7	0.5	0.8	0.6	0.7	0.5	0.6	0.8	0.8
Asthma	0.5	0.9	4.7	-2.2	-1.4	0.4	0.1	0.5	0.6	0.6	0.3	-1.1	0.6	0.9
Medication: Amlodipine	0.5	0.7	1.4	-1.0	-1.2	0.7	0.5	0.8	0.7	0.8	0.8	-0.8	0.8	0.9
Medication: Ventolin 100micrograms inhaler	0.5	0.6	4.5	-2.1	-0.2	0.6	0.2	0.5	0.5	0.7	0.4	-0.2	0.6	0.7
Comparative body size at age 10	0.5	1.4	3.3	-0.7	0.7	1.4	1.8	0.9	1.1	1.1	1.7	1.4	0.6	0.8
Number of children fathered	0.5	0.6	1.1	0.5	0.7	0.8	0.3	0.9	1.0	0.9	0.3	0.0	1.0	1.0
Illnesses of siblings: Diabetes	0.5	0.7	4.8	2.2	0.8	-0.1	0.3	-0.5	0.2	-0.3	0.2	0.8	-0.6	-0.6
Asthma (self-reported)	0.5	1.0	3.6	-1.9	-1.0	0.8	0.5	0.8	1.0	1.0	0.8	-0.7	0.8	1.1
Average weekly champagne plus white wine intake	0.5	0.7	2.4	0.4	1.5	-0.5	-0.1	-1.1	-0.3	-0.6	-0.2	1.0	-1.3	-0.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.1	-0.3	-0.0	0.8	0.9	0.9	0.8	0.6	0.8	1.1	0.8	0.7
Medication: Atorvastatin	0.5	0.7	1.4	-1.0	0.0	0.8	1.2	0.8	0.7	0.7	1.0	0.8	0.7	0.5
Average weekly beer plus cider intake	0.5	0.8	1.2	0.9	0.6	0.9	1.1	1.1	1.1	0.8	1.0	0.4	1.0	0.7
Schizophrenia (2018)	0.4	0.7	6.2	2.5	0.3	0.4	0.7	0.1	0.6	0.2	0.6	0.7	-0.0	-0.1
Ovarian Cancer	0.4	0.6	2.6	-1.6	-1.2	0.3	-0.1	0.5	0.5	0.5	-0.0	-0.8	0.7	0.7
Lupus	0.4	0.6	1.3	0.3	-0.7	-0.8	-1.1	-1.1	-0.3	-0.6	-0.9	-0.1	-1.1	-0.4
Rheumatoid Arthritis	0.4	0.6	3.0	-1.4	-1.7	0.3	-0.0	0.3	0.4	0.3	0.1	-0.6	0.4	0.6
Schizophrenia (2014)	0.4	0.9	7.6	2.8	0.7	0.4	0.6	0.4	0.4	0.3	0.6	0.3	0.3	0.1
Sensitivity / hurt feelings	0.4	0.7	1.3	-0.3	-0.3	1.1	1.0	0.9	0.9	1.0	1.0	0.4	0.9	0.8
Ever had hysterectomy (womb removed)	0.4	0.5	1.8	0.8	1.3	-0.7	-0.3	-0.6	-0.6	-0.6	-0.3	-0.1	-0.7	-0.6
Medication: Co-codamol	0.4	0.5	1.3	0.9	0.2	-0.5	0.0	-0.8	-0.6	-0.9	-0.1	0.8	-0.9	-1.1
Severe depression (siblings)	0.4	0.4	2.3	0.5	0.8	0.3	0.5	-0.3	0.5	-0.0	0.3	1.5	-0.5	-0.4
Serious illness, injury or assault to yourself	0.4	0.5	4.1	-0.4	-2.0	-0.1	-0.5	-0.1	-0.3	0.1	-0.1	-0.9	0.0	0.5
Financial difficulties in last 2 years	0.4	0.5	3.3	-1.8	-1.3	-0.2	-0.3	-0.1	-0.2	-0.2	-0.2	-0.3	-0.0	0.1
Hip circumference	0.4	1.6	2.9	1.0	-0.5	-1.4	-1.1	-1.7	-1.5	-1.6	-1.1	-0.3	-1.7	-1.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.6	1.6	0.0	0.7	0.8	0.4	0.8	0.5	0.7	0.8	0.2	0.3
Depression (self-reported)	0.4	0.5	1.7	-0.1	-0.1	1.0	0.9	0.3	0.9	0.7	0.8	1.3	0.2	0.4
Medication: Lansoprazole	0.4	0.5	1.8	0.3	1.3	-0.4	0.4	-0.6	-0.3	-0.6	0.1	1.0	-0.8	-1.0
Eye problems/disorders: None of the above	0.4	0.5	2.2	0.8	1.5	0.2	0.5	-0.4	-0.1	0.0	0.3	1.2	-0.6	-0.6
Emphysema/chronic bronchitis	0.4	0.4	3.0	1.0	0.2	-0.1	-0.2	0.3	0.2	0.3	0.1	-1.7	0.4	0.5
Medication: Omeprazole	0.4	0.5	0.9	0.3	-0.7	1.0	0.7	0.7	0.7	0.9	0.8	0.5	0.7	0.9
Mean time to correctly identify matches	0.4	0.7	2.7	0.0	-0.5	-1.0	-1.1	-0.2	-1.0	-0.8	-1.0	-1.6	0.0	-0.1
Pulse rate, automated reading	0.4	1.2	1.9	0.2	-0.1	1.3	1.3	1.4	0.8	1.4	1.4	-0.5	1.3	1.1
Smoking status: Previous	0.4	0.6	2.1	1.5	0.5	-0.2	0.2	-0.8	-0.2	-0.6	-0.0	1.3	-0.9	-1.0
Average weekly red wine intake	0.4	0.6	4.2	1.2	2.1	0.2	0.4	0.2	0.2	0.1	0.0	0.9	0.1	-0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.1	-0.1	-1.1	-0.7	-0.9	-0.6	-0.8	-0.7	-0.8	-0.6	-0.6	-0.5
Pain experienced in last month	0.4	0.6	1.8	-0.3	-0.8	-0.9	-1.1	-0.6	-0.8	-0.6	-0.9	-1.3	-0.4	-0.2
Supplements: Calcium	0.4	0.5	0.8	-0.9	-0.3	-0.8	-0.6	-0.6	-0.7	-0.9	-0.9	-0.2	-0.6	-0.9
Basal cell carcinoma (self-reported)	0.4	0.5	1.3	-1.1	-1.1	0.1	0.2	0.9	0.0	0.3	0.1	-1.1	1.0	0.4
Bipolar Disorder or Schizophrenia	0.3	0.7	4.0	2.0	0.3	0.7	0.6	0.6	0.9	0.6	0.5	0.6	0.5	0.4
Irritable Bowel Disease (IBD)	0.3	0.7	2.9	0.7	1.7	-0.2	0.2	-0.7	-0.6	-0.4	-0.0	1.4	-0.8	-0.8
Bipolar Disorder (2011)	0.3	0.3	0.6	-0.4	-0.8	0.1	-0.4	0.5	0.2	0.3	-0.3	-0.8	0.7	0.7
Heel T-Score	0.3	2.5	8.4	1.2	0.8	1.5	2.2	0.0	1.9	1.3	2.2	2.9	-0.5	0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.7	1.0	-0.3	-0.8	-1.0	0.2	-1.0	-0.6	-0.9	-1.3	0.4	0.1
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.2	1.5	0.8	-0.3	0.2	-0.3	-0.3	-0.4	-0.2	0.4	-0.4	-0.7
Impedance of leg (right)	0.3	1.5	2.9	0.6	-0.0	1.3	1.2	1.7	1.1	1.4	1.3	-0.6	1.7	1.5
Hand grip strength (right)	0.3	0.9	2.1	-1.0	-1.4	-1.0	-1.0	-0.7	-0.9	-0.8	-0.9	-1.4	-0.6	-0.4
Age when periods started (menarche)	0.3	0.7	1.6	0.2	0.9	0.9	1.1	0.8	1.3	0.9	0.9	0.4	0.7	0.5
Qualifications: CSEs or equivalent	0.3	0.4	0.8	0.1	0.6	0.8	0.9	0.2	0.9	0.8	0.9	0.9	0.0	0.2
Hearing difficulty/problems with background noise	0.3	0.4	2.2	-0.7	-1.5	0.4	0.5	0.5	0.4	0.1	0.7	-0.1	0.5	0.6
Heart attack	0.3	0.3	0.8	-0.5	-0.2	-0.6	-0.3	-0.6	-0.6	-0.9	-0.3	0.4	-0.7	-0.9
Pulse rate	0.3	0.4	1.1	0.2	0.2	0.9	0.8	0.7	0.7	1.0	0.7	0.4	0.6	0.6
Pulse wave Arterial Stiffness index	0.3	0.3	1.0	-0.3	0.1	-0.6	-0.5	-0.0	-1.0	-0.5	-0.6	-1.0	0.1	-0.4
Headache pain in last month	0.3	0.6	1.1	-0.2	-0.0	-0.8	-0.9	-1.0	-0.8	-0.7	-1.1	0.4	-1.0	-0.8
Birth weight	0.3	0.7	3.9	0.4	1.3	0.5	0.6	-0.2	1.0	0.3	0.1	2.0	-0.3	-0.2
Medication: Ibuprofen	0.3	0.4	3.6	1.9	0.3	0.0	0.0	-0.2	0.4	-0.0	-0.1	0.2	-0.3	-0.1
Medication: Allopurinol	0.3	0.3	1.8	0.3	-0.5	-0.7	-0.7	-0.0	-0.5	-0.3	-0.6	-1.3	0.1	0.2
Heart disease (mother)	0.3	0.4	3.2	-1.8	-0.4	0.0	0.1	0.5	-0.3	-0.1	-0.1	0.0	0.5	0.0
Alcohol intake frequency.	0.3	0.8	3.0	1.1	0.4	-0.2	0.3	-1.0	-0.1	-0.5	0.0	1.7	-1.2	-1.1
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.4	0.0	1.2	-0.2	-0.5	-0.4	-0.3	-0.3	-0.7	1.0	-0.4	-0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	0.6	0.4	-0.7	-0.6	-0.6	-0.6	-0.8	-0.5	-0.2	-0.6	-0.7
Supplements: Vitamin C	0.3	0.4	1.9	1.2	1.4	-0.2	-0.2	-0.5	0.3	-0.2	-0.1	0.5	-0.5	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.1	-1.4	-1.1	0.3	0.1	0.7	0.5	0.3	0.2	-0.4	0.9	0.8
Breast cancer (self-reported)	0.3	0.3	3.3	1.8	0.0	0.0	-0.1	-0.2	0.1	-0.0	-0.2	0.1	-0.2	-0.2
Wears glasses or contact lenses	0.3	0.4	1.8	-0.6	0.5	0.1	-0.3	0.6	0.0	0.3	0.1	-1.3	0.8	0.8
Hearing aid user	0.3	0.3	1.4	0.3	-1.1	-0.1	-0.6	0.2	-0.2	0.0	-0.3	-1.2	0.3	0.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	0.0	0.5	0.6	0.3	1.1	0.5	0.6	0.4	-0.2	1.2	0.8
Medication: Lisinopril	0.3	0.4	1.2	0.9	1.1	-0.5	-0.6	-0.1	-0.6	-0.5	-0.6	-0.8	0.1	-0.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.0	-0.5	-0.1	-0.8	-0.4	-0.8	-0.7	-1.0	-0.4	0.3	-0.8	-0.9
Alcohol drinker status: Previous	0.3	0.4	0.7	-0.4	-0.7	0.6	0.6	0.5	0.8	0.6	0.7	0.5	0.5	0.6
Impedance of whole body	0.3	1.3	2.9	1.0	-0.0	1.1	0.8	1.6	0.9	1.3	0.8	-0.8	1.7	1.4
Bipolar Disorder (2018)	0.2	0.3	0.8	0.1	0.1	0.6	0.1	0.8	0.7	0.7	0.1	0.1	0.9	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.5	-1.0	-0.9	-0.6	-1.1	0.0	-0.5	-0.5	-1.2	-0.7	0.3	-0.2
Schizophrenia vs Biploar Disorder	0.2	0.3	1.2	1.1	0.8	-0.2	0.2	-0.2	-0.5	-0.3	0.2	0.2	-0.3	-0.6
HbA1C	0.2	0.2	1.2	-0.5	0.0	0.3	0.4	0.0	0.6	0.2	-0.3	1.1	-0.1	0.1
Blood Red Count	0.2	2.0	9.1	-0.7	0.2	1.3	2.2	0.6	1.1	1.0	1.8	3.0	0.2	-0.2
Blood White Count	0.2	1.8	7.0	1.6	2.5	0.5	1.1	-0.4	0.4	0.2	0.6	2.6	-0.8	-0.8
Number of treatments/medications taken	0.2	0.4	2.0	1.4	1.2	-0.2	0.0	-0.2	-0.1	-0.3	-0.2	-0.1	-0.3	-0.4
Hearing difficulty/problems: Yes	0.2	0.3	1.0	-1.0	-0.5	-0.4	-0.4	-0.1	-0.5	-0.5	-0.3	-0.7	-0.0	-0.2
Townsend deprivation index at recruitment	0.2	0.3	1.5	-0.3	-0.4	0.4	0.9	0.2	-0.0	0.0	0.7	1.2	-0.0	-0.3
Chronic bronchitis/emphysema (father)	0.2	0.3	1.2	0.3	1.1	-0.4	-0.8	-0.1	-0.4	-0.2	-0.8	-0.2	0.0	0.0
Impedance of leg (left)	0.2	1.2	2.6	0.6	-0.5	1.0	0.7	1.5	0.7	1.2	0.8	-1.2	1.6	1.5
Number of incorrect matches in round	0.2	0.4	0.8	0.5	0.7	-0.5	-0.4	-0.8	-0.1	-0.5	-0.5	0.5	-0.9	-0.7
Diabetes (self-reported)	0.2	0.3	1.1	0.6	0.2	-0.3	-0.7	0.2	-0.3	-0.1	-0.5	-1.0	0.5	0.6
Impedance of arm (right)	0.2	0.9	2.2	1.5	0.8	0.9	0.7	1.2	0.8	1.0	0.6	-0.4	1.3	1.0
Worrier / anxious feelings	0.2	0.3	1.1	0.6	1.0	0.2	0.0	-0.6	0.1	0.0	-0.1	0.9	-0.7	-0.2
Mouth/teeth dental problems: Dentures	0.2	0.3	0.9	-1.0	-0.5	-0.6	-0.3	-0.4	-0.8	-0.6	-0.5	-0.1	-0.4	-0.8
Lung cancer (father)	0.2	0.2	1.0	0.4	0.7	0.3	0.4	-0.2	0.6	0.2	0.3	1.0	-0.3	-0.1
Impedance of arm (left)	0.2	0.7	1.6	1.0	0.5	0.8	0.5	1.2	0.6	0.9	0.5	-0.7	1.3	1.0
Birth weight of first child	0.2	0.3	2.3	-0.3	0.6	0.1	0.3	-0.4	0.2	-0.2	0.3	1.5	-0.6	-0.5
Gout (self-reported)	0.2	0.3	0.8	-0.1	-0.8	-0.6	-0.8	-0.3	-0.6	-0.4	-0.7	-0.9	-0.1	0.1
Exposure to tobacco smoke outside home	0.2	0.3	0.6	-0.4	0.5	0.5	0.6	0.6	0.4	0.5	0.8	-0.5	0.6	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.2	-0.2	-1.1	0.5	0.3	0.5	0.5	0.5	0.3	-0.1	0.5	0.5
Shortness of breath walking on level ground	0.2	0.3	0.7	0.2	-0.1	0.5	0.7	0.5	0.7	0.4	0.8	0.1	0.5	0.4
Migraine (self-reported)	0.2	0.3	1.4	0.5	0.2	-0.2	0.2	-0.3	0.0	-0.5	-0.2	1.2	-0.4	-0.8
Family relationship satisfaction	0.2	0.2	1.3	-1.1	-0.8	0.1	-0.2	-0.0	0.1	0.2	0.0	-0.6	-0.0	0.4
Illnesses of father: Heart disease	0.2	0.3	0.6	-0.5	0.2	0.4	0.5	0.8	0.5	0.5	0.5	-0.1	0.8	0.5
Ever had bowel cancer screening	0.2	0.2	0.5	-0.7	0.3	-0.6	-0.4	-0.2	-0.4	-0.6	-0.6	-0.2	-0.1	-0.5
Osteoporosis (self-reported)	0.2	0.2	0.8	0.9	0.8	-0.1	0.1	-0.3	-0.3	-0.2	-0.0	0.0	-0.3	-0.6
Miserableness	0.2	0.3	1.7	-1.3	-1.0	0.4	0.2	0.2	0.1	0.4	0.4	-0.2	0.2	0.5
Unable to work because of sickness or disability	0.2	0.3	0.9	0.4	0.9	-0.2	0.1	-0.4	-0.5	-0.4	0.1	0.9	-0.5	-0.6
Ulcerative Colitis (UC)	0.1	0.2	0.7	0.3	0.6	0.5	0.8	0.2	0.2	0.4	0.7	0.7	0.1	0.1
Body Mass Index (BMI) (2010)	0.1	0.1	0.5	-0.2	0.7	-0.3	-0.1	-0.3	-0.4	-0.2	0.1	-0.5	-0.4	0.1
Hypothyroidism (self reported)	0.1	0.2	0.6	0.1	0.1	0.5	0.4	0.4	0.5	0.5	0.2	0.8	0.4	0.2
Tanning	0.1	0.8	2.0	0.4	1.4	-0.9	-0.6	-0.8	-0.9	-1.0	-1.1	0.3	-0.8	-1.2
Trunk fat mass	0.1	0.4	1.7	1.3	0.4	0.3	0.8	0.1	0.0	0.1	0.7	0.8	-0.1	-0.2
Waist circumference	0.1	0.5	2.4	0.3	0.1	0.6	1.2	-0.0	0.4	0.2	1.0	1.5	-0.3	-0.3
Had menopause	0.1	0.1	0.5	0.7	0.4	0.1	0.0	0.4	-0.0	0.0	0.2	-0.7	0.4	0.2
Allergy	0.1	0.3	0.5	-0.2	-0.0	0.5	0.4	0.7	0.7	0.6	0.4	-0.1	0.7	0.7
Arm fat mass (right)	0.1	0.5	2.4	0.8	0.6	0.4	1.1	-0.2	0.2	0.0	0.8	1.5	-0.4	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.8	-0.9	-0.9	0.1	-0.2	0.1	-0.2	-0.0	0.0	-0.2	0.2	0.2
Pulse wave peak to peak time	0.1	0.1	0.3	0.2	-0.4	-0.1	-0.3	-0.5	0.3	-0.2	-0.2	0.4	-0.5	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.2	0.4	0.2	0.3	0.3	0.4	0.4	0.2	0.3	0.1	0.5	0.2
Whole body fat mass	0.1	0.4	1.2	1.1	0.5	0.4	1.0	-0.0	0.0	0.0	0.8	0.9	-0.2	-0.3
Leg fat mass (right)	0.1	0.5	1.6	0.8	0.4	0.7	1.3	0.2	0.4	0.3	1.2	0.9	0.0	-0.0
Knee pain experienced in last month	0.1	0.2	0.4	0.3	0.4	-0.5	-0.3	-0.5	-0.3	-0.6	-0.2	-0.2	-0.5	-0.6
Diabetes diagnosed by doctor	0.1	0.2	0.6	0.3	0.1	-0.1	-0.4	0.6	-0.2	0.0	-0.2	-0.8	0.8	0.5
Medication: Aspirin	0.1	0.1	0.3	0.1	-0.2	0.3	0.2	0.4	0.2	0.3	0.3	-0.3	0.5	0.6
Arm fat mass (left)	0.1	0.4	2.0	0.7	0.6	0.3	0.9	-0.3	0.0	-0.1	0.7	1.4	-0.5	-0.5
Myopia	0.1	0.2	1.4	-1.2	0.1	-0.2	-0.2	-0.0	-0.4	-0.1	-0.1	-0.2	0.0	0.1
Heart disease (siblings)	0.1	0.2	0.6	-0.3	-0.6	0.1	-0.3	0.3	0.1	0.2	-0.1	-0.7	0.5	0.5
Leg fat mass (left)	0.1	0.3	1.1	0.7	0.3	0.5	1.1	0.1	0.2	0.2	1.0	0.8	-0.1	-0.1
Blood Eosinophil Count	0.0	0.0	0.2	0.1	-0.4	-0.1	0.1	0.3	-0.2	-0.1	0.0	0.2	0.3	0.1
Chronotype (morning person)	0.0	0.1	0.4	0.0	-0.2	0.2	0.6	0.3	0.3	0.1	0.5	-0.1	0.2	-0.1
Hair Pigment	0.0	0.4	0.8	0.4	-0.1	-0.7	-0.8	-0.5	-0.7	-0.8	-0.7	-0.9	-0.4	-0.6
Taking other prescription medications	0.0	0.1	0.2	-0.2	0.1	0.4	0.3	-0.0	0.2	0.4	0.2	0.3	-0.1	0.2
Blood clot in the leg (DVT)	0.0	0.0	0.2	0.1	-0.3	-0.1	-0.2	-0.1	-0.4	-0.1	-0.2	-0.3	-0.0	0.0
Medication: Aspirin	0.0	0.0	0.1	0.3	0.2	-0.1	0.0	-0.2	-0.1	-0.2	-0.0	0.2	-0.2	-0.1
Osteoarthritis (self-reported)	0.0	0.1	0.2	0.1	0.4	-0.2	-0.2	0.3	0.2	-0.3	-0.3	-0.2	0.4	-0.0
Ever taken oral contraceptive pill	0.0	0.1	0.1	-0.1	-0.2	0.2	0.3	0.2	0.3	0.2	0.2	0.3	0.1	0.2
Risk taking	0.0	0.1	0.4	-0.6	-0.1	-0.1	-0.0	-0.3	0.0	-0.1	-0.0	0.4	-0.3	-0.1
Cholesterol lowering medication	0.0	0.1	0.4	-0.5	-0.1	-0.2	-0.1	0.0	-0.2	-0.2	0.0	-0.6	0.1	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.3	0.5	-0.4	0.1	0.1	0.1	-0.1	0.0	0.1	0.2	0.1	0.0
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.1	0.2	-0.3	-0.1	-0.1	-0.0	-0.4	-0.1	-0.2	-0.2	-0.0	-0.1

Hub : Genes

PENK

Models

Trait associations