Best TWAS P=8.59e-11 · Best GWAS P=1.58e-10 conditioned to 0.00678
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | CTNNAL1 | 0.14 | 0.07 | lasso | 6 | 0.07 | 9.4e-07 | 3.4 | 5.1 | 3.0e-07 | 0.10 | 0.12 | 0.84 | FALSE |
2 | NTR | Blood | C9orf5 | 0.05 | 0.02 | enet | 14 | 0.03 | 2.2e-10 | 3.2 | -5.6 | 2.0e-08 | -0.28 | 0.92 | 0.07 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTNNAL1 | 0.09 | 0.00 | blup | 83 | 0.04 | 1.0e-04 | 3.4 | 6.5 | 8.6e-11 | 0.63 | 0.02 | 0.38 | TRUE |