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chr9:126,844,856-128,824,378

Best TWAS P=4.17e-13 · Best GWAS P=8.37e-13 conditioned to 0.337

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	5.7	-5.7	1.4e-08	0.74	0.96	0.03	FALSE
2	GTEx	Artery Aorta	PRPS1P2	0.08	0.10	lasso	4	0.08	2.1e-05	-4.6	5.6	2.6e-08	-0.85	0.06	0.88	FALSE
3	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	-6.8	-7.2	4.2e-13	0.94	0.02	0.98	TRUE
4	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	5.6	5.7	1.4e-08	-0.65	0.88	0.09	FALSE
5	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	-7.1	6.4	1.5e-10	-0.84	0.05	0.79	FALSE
6	GTEx	Breast Mammary Tissue	PPP6C	0.11	0.08	enet	10	0.08	7.0e-05	5.7	-5.2	1.8e-07	0.66	0.44	0.39	FALSE
7	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	5.6	-5.6	2.2e-08	0.64	0.07	0.10	FALSE
8	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	5.7	-6.1	1.3e-09	0.74	0.08	0.80	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	GOLGA1	0.13	0.00	enet	8	0.06	3.8e-03	5.8	5.5	4.2e-08	-0.60	0.32	0.26	FALSE
10	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	5.8	5.6	1.6e-08	-0.65	0.96	0.04	FALSE
11	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	5.8	5.8	5.6e-09	-0.68	0.64	0.05	FALSE
12	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	5.5	-6.0	1.9e-09	0.67	0.97	0.02	FALSE
13	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	5.7	6.0	2.3e-09	-0.67	0.51	0.41	FALSE
14	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	5.5	6.1	1.0e-09	-0.50	0.08	0.26	FALSE
15	GTEx	Muscle Skeletal	PPP6C	0.03	0.03	enet	6	0.01	3.0e-02	5.6	-5.5	3.6e-08	0.68	0.49	0.12	FALSE
16	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	-7.1	7.1	1.3e-12	-0.95	0.02	0.98	FALSE
17	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	5.5	-6.8	7.7e-12	0.84	0.13	0.87	FALSE
18	GTEx	Nerve Tibial	PRPS1P2	0.11	0.11	enet	9	0.10	1.4e-07	3.8	5.2	2.0e-07	-0.63	0.99	0.01	FALSE
19	GTEx	Ovary	PRPS1P2	0.14	0.14	lasso	2	0.05	2.9e-02	5.6	5.4	8.5e-08	-0.68	0.14	0.31	FALSE
20	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	5.6	5.8	7.0e-09	-0.67	0.88	0.09	FALSE
21	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	5.6	-6.0	1.9e-09	0.77	0.21	0.68	FALSE
22	GTEx	Spleen	PRPS1P2	0.18	0.02	lasso	4	0.04	3.9e-02	4.0	5.2	2.3e-07	-0.63	0.10	0.14	FALSE
23	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	-7.0	-7.2	4.4e-13	0.96	0.02	0.98	FALSE
24	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	5.7	5.8	8.8e-09	-0.72	0.92	0.07	FALSE
25	YFS	Blood	RABEPK	0.12	0.21	bslmm	317	0.22	2.4e-71	5.8	-5.7	9.4e-09	0.67	0.99	0.01	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	5.7	-5.7	1.5e-08	0.68	0.03	0.97	FALSE
27	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WDR38	0.04	0.01	blup	32	0.02	9.5e-04	-2.2	-5.3	1.4e-07	0.36	0.00	0.10	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	5.8	-5.7	1.0e-08	0.68	0.02	0.70	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	5.6	-5.7	1.2e-08	0.67	0.02	0.96	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	-7.2	7.2	6.3e-13	-0.97	0.02	0.91	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP6C	0.06	0.08	lasso	7	0.07	1.8e-07	5.7	-5.5	3.6e-08	0.64	0.02	0.98	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP6C	0.05	0.04	blup	46	0.03	3.8e-03	5.7	-5.5	4.0e-08	0.68	0.02	0.96	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	5.7	-5.6	1.9e-08	0.69	0.02	0.98	FALSE