[Hub]/) : Traits : Whole body water mass :

chr1:177,195,050-178,753,162

Best TWAS P=7.24e-11 · Best GWAS P=5.28e-44 conditioned to 2.34e-24

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC730102 0.18 0.12 lasso 9 0.12 1.4e-14 5.71 -6.3 3.0e-10 -0.31 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous RP11-568K15.1 0.38 0.21 lasso 9 0.20 1.3e-16 5.71 -5.6 2.7e-08 -0.27 1.00 0.00 FALSE
3 GTEx Artery Tibial RP11-568K15.1 0.14 0.10 lasso 4 0.10 2.0e-08 5.73 -5.6 1.7e-08 -0.28 0.98 0.00 FALSE
4 GTEx Breast Mammary Tissue RP11-568K15.1 0.20 0.11 lasso 7 0.09 2.0e-05 5.71 -5.3 8.9e-08 -0.27 0.75 0.01 FALSE
5 GTEx Breast Mammary Tissue (Male) RP11-568K15.1 0.15 0.18 lasso 3 0.15 2.1e-04 5.71 -5.7 1.1e-08 -0.28 0.06 0.08 FALSE
6 GTEx Esophagus Muscularis RP11-568K15.1 0.26 0.17 lasso 7 0.18 5.7e-11 5.73 -5.2 2.3e-07 -0.25 1.00 0.00 FALSE
7 GTEx Heart Atrial Appendage RP11-568K15.1 0.22 0.17 lasso 6 0.18 2.7e-08 5.71 -5.7 1.6e-08 -0.29 0.92 0.01 FALSE
8 GTEx Lung RASAL2-AS1 0.14 0.01 lasso 7 0.05 1.1e-04 0.25 6.5 7.2e-11 0.49 0.52 0.09 TRUE
9 GTEx Lung RP11-568K15.1 0.22 0.06 lasso 5 0.14 6.4e-11 5.71 -5.5 4.6e-08 -0.27 0.99 0.00 FALSE
10 GTEx Muscle Skeletal SEC16B 0.18 0.04 lasso 6 0.05 2.3e-05 5.71 6.3 3.5e-10 0.32 0.47 0.02 FALSE
11 GTEx Muscle Skeletal RP4-798P15.3 0.18 0.02 lasso 6 0.04 1.7e-04 5.71 6.2 4.8e-10 0.32 0.28 0.03 FALSE
12 GTEx Skin Sun Exposed Lower leg RASAL2-AS1 0.06 0.00 enet 23 0.02 1.8e-02 -5.73 6.4 1.6e-10 0.24 0.13 0.04 TRUE
13 GTEx Skin Sun Exposed Lower leg RP11-568K15.1 0.11 0.05 enet 20 0.04 1.3e-04 5.71 -6.4 1.6e-10 -0.38 0.57 0.11 TRUE