Best TWAS P=1.16e-12 · Best GWAS P=2.58e-17 conditioned to 4.27e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PIGC | 0.11 | 0.00 | enet | 21 | 0.01 | 8.4e-02 | -0.55 | 7.1 | 1.2e-12 | 0.40 | 0.05 | 0.24 | TRUE |
| 2 | GTEx | Nerve Tibial | PIGC | 0.10 | 0.02 | enet | 10 | 0.02 | 1.3e-02 | -3.08 | 5.2 | 2.2e-07 | 0.20 | 0.16 | 0.04 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | PIGC | 0.08 | 0.02 | lasso | 5 | 0.02 | 8.8e-03 | 5.30 | 5.5 | 3.1e-08 | -0.07 | 0.52 | 0.02 | TRUE |
| 4 | GTEx | Spleen | PIGC | 0.29 | 0.04 | lasso | 6 | 0.07 | 6.6e-03 | 2.93 | 5.2 | 2.6e-07 | 0.27 | 0.07 | 0.06 | TRUE |
| 5 | GTEx | Testis | METTL13 | 0.29 | 0.05 | lasso | 10 | 0.09 | 9.9e-05 | -3.76 | 6.5 | 1.0e-10 | 0.34 | 0.23 | 0.16 | TRUE |