Best TWAS P=6.6e-08 · Best GWAS P=2.22e-07 conditioned to 0.0191
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | NDRG4 | 0.18 | 0.13 | lasso | 8 | 0.18 | 9.2e-10 | -3.9 | 5.4 | 6.6e-08 | 0.62 | 0.08 | 0.90 | TRUE |
| 2 | YFS | Blood | CNOT1 | 0.10 | 0.12 | bslmm | 486 | 0.12 | 4.0e-37 | 5.1 | 5.3 | 1.0e-07 | 0.99 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NDRG4 | 0.04 | 0.01 | blup | 71 | 0.01 | 1.2e-02 | -1.7 | 5.2 | 1.9e-07 | 0.81 | 0.01 | 0.86 | FALSE |