[Hub]/) : Traits : Whole body water mass : ← →

chr1:21,680,408-24,216,118

Best TWAS P=1.21e-13 · Best GWAS P=2.46e-13 conditioned to 0.0192

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HTR1D 0.11 0.07 enet 21 0.09 1.1e-10 -5.4 6.3 3.8e-10 -0.78 0.48 0.52 FALSE
2 GTEx Brain Cortex LUZP1 0.23 0.14 lasso 5 0.10 7.8e-04 -7.2 7.2 4.5e-13 -1.00 0.02 0.81 FALSE
3 GTEx Brain Frontal Cortex BA9 RP1-184J9.2 0.38 0.00 lasso 11 0.00 4.3e-01 -6.8 5.7 1.5e-08 -0.54 0.05 0.18 FALSE
4 GTEx Cells Transformed fibroblasts LUZP1 0.09 0.09 lasso 4 0.08 2.8e-06 -7.2 7.2 4.4e-13 -1.00 0.01 0.99 FALSE
5 GTEx Esophagus Muscularis RP1-184J9.2 0.07 0.08 enet 6 0.05 6.1e-04 -5.4 5.1 2.8e-07 -0.72 0.37 0.49 FALSE
6 GTEx Muscle Skeletal LUZP1 0.07 0.08 enet 14 0.08 3.5e-08 3.5 5.7 1.3e-08 -0.62 0.07 0.92 FALSE
7 GTEx Skin Sun Exposed Lower leg KDM1A 0.09 0.01 lasso 5 0.01 1.1e-01 -6.8 -5.3 1.1e-07 0.39 0.10 0.47 FALSE
8 GTEx Testis LUZP1 0.17 0.09 lasso 4 0.08 2.6e-04 -6.8 -6.8 9.6e-12 0.55 0.09 0.71 FALSE
9 METSIM Adipose LUZP1 0.07 0.00 enet 30 0.01 1.1e-02 3.5 5.4 7.5e-08 -0.36 0.11 0.49 FALSE
10 ROSMAP Brain Pre-frontal Cortex CDC42 0.07 0.02 lasso 6 0.04 5.7e-06 2.5 5.2 1.5e-07 0.01 0.08 0.90 TRUE
11 The Cancer Genome Atlas Breast Invasive Carcinoma WNT4 0.03 0.01 blup 72 0.02 3.8e-05 4.3 6.1 8.7e-10 -0.04 0.26 0.49 TRUE
12 The Cancer Genome Atlas Colon Adenocarcinoma HTR1D 0.10 0.07 enet 7 0.08 3.8e-05 -6.3 6.9 3.9e-12 -0.94 0.02 0.98 FALSE
13 The Cancer Genome Atlas Pancreatic Adenocarcinoma HTR1D 0.24 0.12 lasso 4 0.12 1.2e-05 -6.9 7.4 1.2e-13 -0.76 0.04 0.95 TRUE
14 The Cancer Genome Atlas Rectum Adenocarcinoma HTR1D 0.19 0.12 enet 11 0.13 7.3e-04 -7.3 6.8 1.1e-11 -0.94 0.01 0.91 FALSE