Best TWAS P=1.05e-08 · Best GWAS P=3.73e-17 conditioned to 1.49e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | FAM124B | 0.08 | 0.00 | lasso | 4 | 0.00 | 4.6e-01 | 5.7 | -5.3 | 9.2e-08 | 0.11 | 0.02 | 0.79 | TRUE |
| 2 | GTEx | Adrenal Gland | FAM124B | 0.31 | 0.17 | lasso | 4 | 0.17 | 9.2e-07 | 5.1 | -5.3 | 1.5e-07 | 0.09 | 0.02 | 0.95 | FALSE |
| 3 | GTEx | Muscle Skeletal | KCNE4 | 0.06 | 0.01 | lasso | 2 | 0.00 | 2.4e-01 | -5.7 | -5.7 | 1.0e-08 | 0.41 | 0.19 | 0.06 | TRUE |