[Hub]/) : Traits : Whole body water mass :

chr3:37,692,342-39,280,382

Best TWAS P=3.04e-13 · Best GWAS P=1.33e-11 conditioned to 0.607

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ACVR2B 0.08 0.08 enet 15 0.09 9.6e-11 -5.6 6.2 7.4e-10 -0.88 0.15 0.85 FALSE
2 GTEx Adipose Subcutaneous EXOG 0.10 0.00 enet 12 0.00 1.3e-01 -6.6 -6.2 4.5e-10 0.68 0.02 0.76 FALSE
3 GTEx Brain Cerebellum EXOG 0.19 0.23 enet 4 0.21 7.7e-07 -6.7 -6.7 2.3e-11 0.99 0.02 0.98 FALSE
4 GTEx Brain Cerebellum ACVR2B-AS1 0.25 0.07 lasso 6 0.10 8.3e-04 -6.6 -6.6 4.3e-11 0.91 0.02 0.95 FALSE
5 GTEx Brain Frontal Cortex BA9 EXOG 0.18 0.08 lasso 4 0.05 1.7e-02 -6.7 -6.7 2.2e-11 0.99 0.02 0.89 FALSE
6 GTEx Breast Mammary Tissue EXOG 0.08 0.06 enet 10 0.05 8.6e-04 -5.8 -7.3 3.0e-13 0.90 0.03 0.95 TRUE
7 GTEx Colon Transverse XYLB 0.08 0.03 enet 15 0.05 1.7e-03 -6.7 6.4 1.2e-10 -0.85 0.03 0.94 FALSE
8 GTEx Esophagus Mucosa EXOG 0.13 0.05 lasso 3 0.03 5.0e-03 -6.6 -6.8 9.3e-12 0.98 0.02 0.94 FALSE
9 GTEx Nerve Tibial EXOG 0.10 0.00 lasso 5 0.00 1.7e-01 -6.6 -5.4 7.5e-08 0.87 0.02 0.89 FALSE
10 GTEx Ovary EXOG 0.33 0.25 lasso 8 0.21 8.1e-06 -6.3 -6.6 4.3e-11 0.90 0.05 0.83 FALSE
11 GTEx Pancreas EXOG 0.22 0.08 enet 15 0.03 2.6e-02 -6.7 -5.9 3.7e-09 0.91 0.03 0.94 FALSE
12 GTEx Stomach EXOG 0.14 0.05 lasso 6 0.02 2.5e-02 -6.7 -6.7 2.0e-11 1.00 0.02 0.97 FALSE
13 GTEx Testis EXOG 0.35 0.28 lasso 5 0.26 8.1e-12 -6.8 -6.8 7.9e-12 1.00 0.01 0.99 FALSE
14 GTEx Thyroid EXOG 0.19 0.20 lasso 3 0.19 2.9e-14 -6.6 -6.6 3.8e-11 0.98 0.01 0.99 FALSE
15 NTR Blood ACVR2B 0.02 0.02 lasso 3 0.02 5.6e-07 -6.3 -6.6 3.4e-11 0.95 0.03 0.96 FALSE
16 NTR Blood EXOG 0.02 0.03 lasso 6 0.03 1.0e-09 -5.6 6.0 2.6e-09 -0.89 0.16 0.84 FALSE
17 NTR Blood XYLB 0.05 0.06 lasso 3 0.06 6.2e-18 -6.3 -6.4 1.8e-10 0.87 0.12 0.88 FALSE
18 ROSMAP Brain Pre-frontal Cortex EXOG 0.10 0.13 lasso 2 0.12 4.8e-15 -6.6 -6.2 5.6e-10 0.98 0.02 0.98 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EXOG 0.04 0.01 blup 56 0.03 2.2e-04 -6.3 -5.5 4.0e-08 0.82 0.02 0.85 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XYLB 0.03 0.03 blup 82 0.02 5.1e-03 -6.5 5.8 5.0e-09 -0.91 0.01 0.98 FALSE
21 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EXOG 0.14 0.09 blup 56 0.09 9.5e-06 -6.6 -6.3 3.4e-10 0.88 0.01 0.99 FALSE
22 The Cancer Genome Atlas Liver Hepatocellular Carcinoma LOC100128640 0.09 0.05 lasso 2 0.03 1.7e-02 -6.3 6.3 2.5e-10 -0.86 0.02 0.52 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EXOG 0.02 0.02 blup 56 0.01 1.0e-02 -6.4 -6.5 7.0e-11 0.96 0.02 0.86 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma XYLB 0.05 0.03 lasso 4 0.02 2.4e-03 -6.1 6.2 6.5e-10 -0.93 0.02 0.97 FALSE
25 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EXOG 0.10 0.02 blup 56 0.03 2.1e-02 -2.5 -5.2 2.2e-07 0.82 0.02 0.57 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma LOC100128640 0.08 0.02 blup 28 0.03 2.6e-04 -6.7 6.0 1.6e-09 -0.87 0.01 0.98 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma XYLB 0.05 0.06 enet 7 0.05 3.5e-06 -6.5 5.9 3.4e-09 -0.95 0.00 1.00 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma ACVR2B 0.02 0.00 blup 49 0.01 1.6e-02 -6.4 6.4 1.3e-10 -0.92 0.03 0.48 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma EXOG 0.11 0.05 blup 56 0.10 9.5e-10 -6.6 -5.6 2.0e-08 0.83 0.01 0.99 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma LOC100128640 0.07 0.03 blup 28 0.03 1.0e-03 -6.7 6.4 1.9e-10 -0.96 0.01 0.98 FALSE