TWAS hub - LOC100128640

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Liver Hepatocellular Carcinoma	0.0880	0.0790	6.6e-03	0.049	0.020	0.003	NA	0.028	0.0024	0.03700	0.2300	NA	0.0170
2	TCGA	Prostate Adenocarcinoma	0.0803	0.0475	6.5e-05	0.024	0.032	0.022	NA	0.023	0.0012	0.00026	0.0019	NA	0.0016
3	TCGA	Thyroid Carcinoma	0.0670	0.0490	5.1e-05	0.026	0.027	0.019	NA	0.026	0.0013	0.00100	0.0056	NA	0.0012

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Impedance of arm (right)	24.0	111.9	125.4	-10.4	-10.1	-11.2
Impedance of arm (left)	22.5	104.3	118.8	-10.1	-9.6	-10.9
Impedance of whole body	16.1	81.7	94.3	-8.9	-8.5	-9.7
Arm predicted mass (right)	10.1	51.9	53.4	7.2	7.1	7.3
Arm fat-free mass (right)	9.9	50.7	52.6	7.1	7.0	7.2
Trunk fat-free mass	8.5	48.7	50.9	7.1	6.7	7.1
Trunk predicted mass	8.5	48.4	51.1	7.1	6.6	7.1
Arm fat-free mass (left)	8.4	42.6	43.8	6.6	6.3	6.6
Arm predicted mass (left)	8.2	41.7	44.2	6.5	6.2	6.7
Alcohol intake frequency.	7.0	16.3	20.2	-4.1	-3.5	-4.5
Whole body water mass	6.8	39.0	40.5	6.3	6.0	6.4
Whole body fat-free mass	6.7	38.4	39.8	6.3	6.0	6.3
Birth weight	6.3	13.7	16.8	4.0	3.0	4.1
Bilateral oophorectomy (both ovaries removed)	6.2	7.2	7.7	2.7	2.5	2.8
Impedance of leg (left)	6.0	29.3	33.5	-5.2	-5.2	-5.8
Falls in the last year	5.7	7.7	9.2	-2.5	-3.0	-2.8
Impedance of leg (right)	5.6	27.3	32.7	-5.0	-4.9	-5.7
Number of incorrect matches in round	5.4	8.9	10.5	2.9	2.8	3.2
Reason for reducing amount of alcohol drunk: Health precaution	5.3	6.2	7.8	2.5	2.1	2.8
Schizophrenia (2014)	5.2	11.4	12.2	3.5	3.2	3.4
Diabetes (mother)	5.2	6.6	8.6	2.9	1.7	2.9
Basal metabolic rate	5.2	28.8	29.9	5.4	5.2	5.5
Supplements: Fish oil (including cod liver oil)	4.9	6.5	8.6	2.9	2.4	2.3
Hand grip strength (right)	4.8	12.9	17.4	3.5	3.0	4.2
Number of operations (self-reported)	4.7	7.0	7.5	-2.6	-2.6	-2.7
Chronotype (morning person)	4.6	10.6	13.1	-2.9	-3.2	-3.6
Ever had hysterectomy (womb removed)	4.4	5.0	6.2	2.5	2.0	2.2
Hand grip strength (left)	4.2	11.0	16.8	3.2	2.4	4.1
Medication: Paracetamol	4.2	6.5	8.5	-2.6	-2.1	-2.9
Age when periods started (menarche)	4.1	9.9	12.3	-3.4	-2.5	-3.5
Tinnitus: Yes, but not now, but have in the past	3.9	4.1	6.7	-1.9	-2.6	-1.4
Tense / ‘highly strung’	3.9	6.5	7.4	2.5	2.3	2.7
Lung FVC	3.8	19.4	22.2	4.7	4.0	4.5
Comparative body size at age 10	3.8	10.5	12.1	3.0	3.2	3.5
Maternal smoking around birth	3.7	5.4	6.1	2.0	2.5	2.4
Leg predicted mass (right)	3.5	18.6	19.6	4.3	4.2	4.4
Schizophrenia (2018)	3.4	7.0	9.1	2.7	2.1	3.0
Osteoporosis (self-reported)	3.4	4.2	7.1	-2.0	-1.2	-2.7
BMI	3.3	18.9	21.4	4.0	4.3	4.6
Leg fat-free mass (left)	3.3	17.4	18.3	4.1	4.1	4.3
Leg predicted mass (left)	3.3	17.7	18.5	4.2	4.1	4.3
Illnesses of siblings	3.3	4.6	5.9	-1.9	-2.0	-2.4
Mouth/teeth dental problems: Bleeding gums	3.3	4.3	7.0	2.2	1.0	2.6
Leg fat-free mass (right)	3.3	17.9	19.0	4.2	4.1	4.4
Alcohol drinker status: Never	3.3	3.9	5.5	-2.2	-1.2	-2.3
Bipolar Disorder or Schizophrenia	3.2	7.8	10.4	2.9	2.2	3.2
Relative age voice broke	3.1	4.7	5.2	-1.9	-2.3	-2.3
Loud music exposure frequency	3.0	3.3	3.9	-1.5	-2.0	-1.9
Average weekly red wine intake	3.0	4.4	4.6	2.1	2.1	2.1
Bipolar Disorder (2011)	2.9	2.8	3.8	1.9	1.6	1.4
Time employed in main current job	2.9	3.3	5.3	2.0	0.9	2.3
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.3	5.2	1.8	1.3	2.3
Illnesses of father: High blood pressure	2.8	3.4	3.7	1.9	1.8	1.9
Trunk fat percentage	2.6	10.5	13.1	-3.6	-2.8	-3.3
Worry too long after embarrassment	2.6	4.3	5.7	2.0	1.7	2.4
Osteoarthritis (self-reported)	2.6	3.4	3.6	-1.9	-1.7	-1.9
Financial situation satisfaction	2.6	3.2	6.3	-1.5	-2.5	-1.1
Mouth/teeth dental problems: Mouth ulcers	2.5	4.0	5.7	-2.4	-1.9	-1.7
Ovarian Cancer	2.4	3.1	4.6	-2.1	-1.0	-1.9
Stomach or abdominal pain in last month	2.4	2.9	3.7	1.9	1.2	1.9
Number of live births	2.4	3.3	4.2	-1.7	-2.1	-1.7
Peak expiratory flow (PEF)	2.4	5.5	8.1	2.8	1.3	2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	4.0	1.9	1.2	2.0
Medication for pain relief, constipation, heartburn	2.4	4.1	5.8	2.0	1.6	2.4
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.6	4.8	2.2	1.5	1.9
Forced vital capacity (FVC)	2.3	8.7	13.0	3.6	2.4	2.7
Mouth/teeth dental problems: Loose teeth	2.2	2.6	4.2	1.3	1.3	2.0
Heel T-Score	2.1	16.8	19.2	4.0	4.4	3.9
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	3.2	-1.5	-1.4	-1.8
Exposure to tobacco smoke at home	2.1	2.3	3.7	-1.9	-1.2	-1.3
Had major operations	2.1	2.4	2.6	-1.5	-1.6	-1.5
Supplements: Vitamin C	2.1	2.5	4.2	2.0	1.0	1.5
Mineral and other dietary supplements	2.1	2.8	4.6	-2.1	-1.5	-1.3
Pack years of smoking	2.1	3.1	4.2	1.8	2.1	1.3
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	3.3	-1.4	-1.8	-1.5
Systolic blood pressure, automated reading	1.9	5.5	7.0	2.6	1.9	2.4
Diabetes (father)	1.9	2.4	4.2	1.4	2.0	1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.9	4.3	5.0	2.2	2.1	1.9
Chest pain or discomfort	1.9	2.7	3.2	-1.7	-1.8	-1.4
Illnesses of father: None of the above (group 1)	1.9	2.3	3.5	-1.5	-1.9	-1.2
Alzheimer’s Disease (in father)	1.8	1.9	2.1	1.5	1.2	1.4
Mean Putamen Volume	1.8	2.1	3.8	-1.4	-2.0	-0.8
Medication: Allopurinol	1.8	2.4	5.6	0.7	2.4	1.1
Alzheimer’s Disease (in mother)	1.7	2.0	2.6	-1.6	-1.2	-1.4
Vitamin and mineral supplements	1.7	2.3	4.1	-2.0	-1.4	-1.0
Pack years adult smoking proportion	1.7	2.6	3.4	1.7	1.9	1.2
Forced expiratory volume in 1-second (FEV1)	1.7	5.8	9.0	3.0	1.9	2.2
Birth weight of first child	1.7	3.1	3.9	1.8	1.5	2.0
Forced vital capacity (FVC), Best measure	1.7	6.3	9.5	3.1	2.0	2.3
Long-standing illness, disability or infirmity	1.7	2.6	3.4	-1.8	-1.1	-1.8
Commuting to job workplace: Walk	1.7	1.9	2.8	-1.7	-0.4	-1.6
Smoking status: Current	1.7	2.8	3.6	1.9	1.6	1.5
Smoking Status	1.6	3.8	5.1	2.3	1.7	1.8
Body mass index (BMI)	1.6	7.0	8.3	2.2	2.8	2.9
Number of full brothers	1.6	2.0	2.6	1.6	1.6	1.0
Emphysema/chronic bronchitis	1.6	1.8	2.2	-1.4	-1.1	-1.5
Number of full sisters	1.6	2.0	3.4	-1.1	-1.8	-1.1
Body Mass Index (BMI) (2010)	1.5	2.0	2.5	1.3	1.3	1.6
Alcohol intake versus 10 years previously	1.5	2.2	2.5	-1.6	-1.3	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	7.5	2.7	1.7	2.0
Medication: Paracetamol	1.5	2.5	4.0	-1.5	-1.1	-2.0
Wears glasses or contact lenses	1.5	1.8	1.9	1.4	1.4	1.2
Pulse wave reflection index	1.4	1.7	2.3	-1.5	-0.8	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	2.4	-1.0	-1.2	-1.5
Handedness (chirality/laterality): Left-handed	1.4	1.7	2.5	-1.6	-1.1	-1.2
Age at First Birth	1.3	1.9	2.2	-1.5	-1.2	-1.4
Supplements: Zinc	1.3	1.4	1.8	1.2	1.0	1.3
Multivitamins +/- minerals	1.3	1.7	2.9	1.3	1.7	0.7
Weight	1.3	6.6	7.0	2.4	2.6	2.6
Mouth/teeth dental problems: Dentures	1.3	2.3	3.0	-1.5	-1.2	-1.7
Ever taken oral contraceptive pill	1.3	1.4	2.4	1.3	0.4	1.6
Current tobacco smoking	1.2	2.0	2.7	1.6	1.3	1.2
Depression (self-reported)	1.2	1.5	2.3	1.3	0.7	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	3.3	1.8	0.3	1.5
Body fat percentage	1.2	4.8	6.4	-2.5	-1.8	-2.2
Medication: Lisinopril	1.2	1.6	1.9	1.2	1.4	1.1
Type 2 Diabetes (T2D) (2012)	1.1	1.2	1.8	-0.9	-1.3	-1.0
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	2.6	-1.6	-0.5	-1.3
Average weekly fortified wine intake	1.1	1.2	2.0	-1.4	-0.6	-1.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.7	-1.3	-0.7	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	4.7	1.5	2.2	0.9
Breastfed as a baby	1.1	1.4	1.6	-1.0	-1.2	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	2.9	1.7	1.1	1.6
Cholesterol lowering medication	1.1	1.6	2.8	-1.2	-0.8	-1.7
Reaction Time	1.0	1.9	2.4	-1.6	-1.6	-1.0
High blood pressure	1.0	2.8	5.6	1.3	2.4	1.1
Chronic bronchitis/emphysema (father)	1.0	1.2	2.1	-1.1	-1.4	-0.6
Arm fat percentage (right)	1.0	3.9	5.3	-2.3	-1.7	-1.9
Eye problems/disorders: None of the above	1.0	1.2	1.9	1.1	-0.6	1.4
Illnesses of siblings: Diabetes	1.0	1.2	2.0	1.2	0.6	1.4
Back pain experienced in last month	1.0	1.5	2.1	1.3	1.4	0.9
Bipolar Disorder (2018)	0.9	1.4	1.9	1.2	0.9	1.4
Medication: Lansoprazole	0.9	1.1	1.7	-0.7	-1.3	-1.0
Hair/balding pattern: Pattern 4	0.9	2.2	3.2	-1.2	-1.4	-1.8
Headache pain in last month	0.9	1.5	2.2	-1.1	-1.5	-1.1
Medication: Amlodipine	0.9	1.2	1.4	1.1	1.2	1.0
High blood pressure (siblings)	0.9	1.3	1.5	1.1	1.2	1.1
Hypertension (Self-reported)	0.9	2.6	5.3	1.2	2.3	1.0
Illnesses of father: Heart disease	0.9	1.2	2.6	0.7	1.6	0.7
Verbal and Numeric Reasoning (VNR)	0.8	1.8	5.2	0.5	2.3	0.3
Coronary Artery Disease (CAD)	0.8	0.9	2.1	1.4	0.6	0.6
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.0	0.9	0.6	1.4
Fluid intelligence score	0.8	1.7	4.7	0.5	2.2	0.5
Medication: Seretide 50 evohaler	0.8	0.9	1.7	-1.0	0.1	-1.3
Mean time to correctly identify matches	0.8	1.6	2.5	-1.6	-1.3	-0.8
Leg fat mass (right)	0.8	3.0	3.6	1.4	1.9	1.9
Medication: Aspirin	0.8	1.0	3.0	0.2	1.7	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	2.2	1.5	1.1	1.3
Miserableness	0.8	1.5	2.5	1.3	1.6	0.5
Myopia	0.8	1.2	1.8	-0.8	-1.4	-1.1
Leg fat mass (left)	0.8	3.1	3.8	1.4	1.9	1.9
Fasting Glucose	0.7	0.8	1.1	0.8	0.8	1.1
Average weekly spirits intake	0.7	0.9	1.8	0.8	0.4	1.4
Hearing difficulty/problems: Yes	0.7	1.0	1.9	-0.3	-1.4	-1.0
Taking other prescription medications	0.7	1.1	2.0	-0.8	-1.4	-0.9
Medication: Atenolol	0.7	0.9	2.4	0.2	1.5	0.4
Hair/balding pattern: Pattern 2	0.7	0.9	1.8	-1.3	-0.5	-0.9
Mouth/teeth dental problems	0.7	1.1	1.8	1.2	1.4	0.1
Medication: Simvastatin	0.7	1.0	2.2	-0.9	-0.1	-1.5
Medication: Ventolin 100micrograms inhaler	0.7	0.9	1.4	-0.6	-1.2	-0.9
Exposure to tobacco smoke outside home	0.7	0.9	1.7	-0.8	-0.5	-1.3
Medication: Ibuprofen	0.7	0.9	1.3	-0.8	-1.2	-0.9
Arm fat percentage (left)	0.7	2.9	4.3	-2.1	-1.2	-1.7
Loneliness, isolation	0.7	0.9	1.3	-1.2	-0.5	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.1	-0.9	-0.4	-1.1
Basal cell carcinoma (self-reported)	0.7	0.8	1.0	-1.0	-0.9	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.2	0.7	1.5	0.3
Heart disease (siblings)	0.7	0.9	1.7	0.6	1.3	0.7
Relative age of first facial hair	0.6	1.3	2.2	-0.6	-1.5	-1.2
Medication for hormone replacement therapy	0.6	0.6	0.8	-0.6	-0.9	-0.9
Severe depression (siblings)	0.6	0.6	1.2	0.8	0.4	1.1
Financial difficulties in last 2 years	0.6	0.8	1.1	1.1	0.8	0.8
Heart attack	0.6	0.8	1.8	-0.6	0.5	-1.3
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.5	-0.5	-1.6	-0.4
Glaucoma (self-reported)	0.6	0.7	1.8	0.2	-0.3	1.4
Medication: Blood pressure	0.6	1.1	2.7	0.6	1.7	0.2
Pulse rate, automated reading	0.6	2.0	3.0	1.7	0.2	1.7
Eye problems/disorders: Cataract	0.6	0.7	1.1	0.1	1.0	-1.0
Medication: Gliclazide	0.6	0.7	1.0	-0.9	0.5	-1.0
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.9	-0.6	0.5	-1.4
HDL Cholesterol	0.5	0.8	1.0	-1.0	-0.8	-0.9
Hypothyroidism (self reported)	0.5	1.1	2.5	0.9	1.6	0.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.3	-0.3	1.1	-0.4
Qualifications: CSEs or equivalent	0.5	0.6	1.7	0.4	0.1	1.3
Serious illness, injury or assault to yourself	0.5	0.6	0.9	-0.6	-0.9	-0.7
Waist circumference	0.5	2.0	2.8	1.0	1.7	1.5
Had menopause	0.5	0.6	1.0	-1.0	-0.4	-0.9
Had other major operations	0.5	0.7	1.1	-0.9	-0.2	-1.0
Blood clot in the leg (DVT)	0.5	0.7	1.6	0.6	1.2	0.4
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.1	0.8	1.5	0.2
Number of children fathered	0.5	0.5	1.0	0.8	-0.0	1.0
Mood swings	0.5	0.9	1.0	1.0	0.8	1.0
Medication: Aspirin	0.5	0.6	1.5	-0.3	1.2	-0.6
Age started oral contraceptive pill	0.5	0.6	1.1	0.7	0.4	1.0
Diastolic blood pressure, automated reading	0.5	1.4	2.1	1.5	1.0	1.0
Depressed Affect (Nagel 2018)	0.4	0.8	1.1	-0.8	-0.8	-1.0
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.2	0.7	1.8	0.4
Alzheimer’s Disease (including proxy)	0.4	0.5	0.8	-0.9	-0.5	-0.7
Irritable Bowel Disease (IBD)	0.4	0.8	1.0	-1.0	-0.9	-0.8
Ulcerative Colitis (UC)	0.4	0.7	1.2	-1.1	-0.9	-0.5
Lupus	0.4	0.7	2.0	-0.0	1.4	0.1
Respiratory disease	0.4	0.8	0.9	-0.9	-0.9	-0.9
Hayfever, allergic rhinitis or eczema	0.4	0.9	1.6	1.3	0.4	1.0
Neuroticism score	0.4	0.9	1.1	1.0	1.0	0.9
Hair/balding pattern: Pattern 3	0.4	0.5	1.1	0.6	0.5	1.0
Happiness	0.4	0.5	0.7	-0.9	-0.7	-0.6
Asthma	0.4	0.8	1.0	0.9	1.0	0.8
Length of working week for main job	0.4	0.5	1.3	0.5	1.1	-0.0
Heart disease (mother)	0.4	0.5	0.8	-0.7	-0.1	-0.9
Irritability	0.4	0.7	1.3	-0.5	-1.1	-0.7
Unable to work because of sickness or disability	0.4	0.6	0.9	-0.8	-0.9	-0.5
Vascular/heart problems diagnosed by doctor	0.4	1.1	2.8	-0.6	-1.7	-0.6
Neuroticism (Nagel 2018)	0.3	0.6	0.7	-0.7	-0.8	-0.8
Crohns Disease (2017)	0.3	0.6	0.7	-0.6	-0.8	-0.8
Rheumatoid Arthritis	0.3	0.4	0.5	-0.6	-0.7	-0.7
Ulcerative Colitis	0.3	0.5	0.7	-0.8	-0.8	-0.3
Blood Eosinophil Count	0.3	2.0	2.9	-1.7	-0.8	-1.6
Number of treatments/medications taken	0.3	0.6	0.8	-0.9	-0.5	-0.8
Sensitivity / hurt feelings	0.3	0.6	1.0	0.7	1.0	0.4
Alcohol usually taken with meals	0.3	0.4	1.1	0.1	1.0	-0.4
Allergy	0.3	0.8	1.1	-1.1	-0.7	-0.8
Medication: Ramipril	0.3	0.4	0.9	-0.9	0.0	-0.6
Lung cancer (father)	0.3	0.3	0.6	-0.3	-0.8	-0.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.3	-1.1	0.0	-0.6
Gout (self-reported)	0.3	0.5	1.3	-0.3	1.1	-0.1
Shortness of breath walking on level ground	0.3	0.4	0.8	0.9	0.1	0.5
Migraine (self-reported)	0.3	0.3	0.8	-0.3	-0.9	-0.3
Comparative height size at age 10	0.3	1.9	2.8	1.7	0.8	1.5
Family relationship satisfaction	0.3	0.4	0.5	-0.7	-0.2	-0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.6	0.2	0.8	0.5
Smoking status: Previous	0.3	0.5	0.9	-0.7	-0.9	-0.4
Qualifications: nursing, teaching	0.3	0.4	0.7	-0.7	0.4	-0.8
Hearing aid user	0.3	0.4	0.7	-0.2	-0.8	-0.6
Commuting to job workplace: Cycle	0.3	0.4	0.5	-0.6	-0.7	-0.6
Pain experienced in last month	0.3	0.6	1.0	0.7	0.6	1.0
Schizophrenia vs Biploar Disorder	0.2	0.3	0.4	-0.6	-0.5	-0.4
Major Depression (MDD)	0.2	0.3	0.6	0.3	0.8	-0.5
HbA1C	0.2	0.2	0.4	-0.3	-0.0	-0.6
Blood Red Count	0.2	2.2	2.9	1.6	1.0	1.7
Cardiovascular Disease	0.2	0.6	1.8	0.1	1.3	-0.2
Medication: Co-codamol	0.2	0.2	0.5	-0.3	0.2	-0.7
Medication: Metformin	0.2	0.3	0.6	-0.2	0.8	-0.4
Townsend deprivation index at recruitment	0.2	0.3	0.7	-0.2	0.9	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.4	0.6	0.4	0.6
Trunk fat mass	0.2	0.9	1.6	-1.3	-0.6	-0.9
Pulse rate	0.2	0.3	0.4	0.6	-0.4	0.6
Noisy workplace	0.2	0.2	0.5	0.7	-0.1	0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.1	-0.6	1.1	-0.3
Medication: Cholesterol lowering	0.2	0.3	0.4	-0.6	0.7	-0.5
Prospective memory result	0.2	0.2	0.3	-0.5	-0.5	0.0
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.5	0.5	0.7	0.1
Health satisfaction	0.2	0.3	0.5	-0.5	-0.4	-0.7
Qualifications: College or University degree	0.2	0.6	1.8	0.2	1.3	-0.1
Overall health rating	0.2	0.4	0.6	-0.8	-0.5	-0.7
Age at last live birth	0.2	0.3	0.4	-0.6	-0.5	-0.6
Leg pain on walking	0.2	0.3	0.8	0.0	-0.9	-0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.8	0.1	-0.9	-0.2
Diabetes diagnosed by doctor	0.2	0.3	0.5	-0.2	0.7	-0.4
Friendships satisfaction	0.2	0.2	0.3	-0.3	-0.5	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	-0.2	-0.7	-0.1
Breast cancer (self-reported)	0.2	0.3	0.5	-0.6	-0.1	-0.7
Asthma (self-reported)	0.2	0.4	0.6	0.5	0.8	0.5
Average weekly champagne plus white wine intake	0.2	0.3	0.7	-0.8	-0.5	-0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.4	-0.2	-0.5	-0.7
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	-0.3	-0.3	0.7
High cholesterol (Self-reported)	0.2	0.4	0.4	-0.6	0.5	-0.7
Medication: Bendroflumethiazide	0.2	0.4	0.7	-0.4	0.9	-0.5
Medication: Atorvastatin	0.2	0.2	0.4	-0.6	-0.4	-0.2
Risk taking	0.2	0.3	0.7	-0.4	-0.1	-0.8
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.4	-0.3	-0.7
Depression (Nagel 2018)	0.1	0.2	0.4	-0.1	-0.6	-0.4
Breast Cancer	0.1	0.3	0.5	-0.5	-0.7	-0.1
LDL Cholesterol	0.1	0.2	0.3	-0.3	-0.4	-0.5
Neuroticism (2016)	0.1	0.1	0.1	0.3	-0.3	0.3
Primary Biliary Cirrhosis	0.1	0.1	0.2	0.4	0.3	0.5
Triglycerides	0.1	0.2	0.2	0.5	0.4	0.1
Blood Platelet Count	0.1	0.9	1.8	-0.9	-0.3	-1.3
Blood White Count	0.1	0.6	1.4	0.4	1.2	0.6
Waist Hip Ratio (WHR)	0.1	0.7	1.1	-1.1	-0.2	-0.9
Systolic Blood Pressure	0.1	0.3	0.4	0.5	0.6	0.5
Allergy or Eczema	0.1	0.1	0.4	-0.1	-0.6	-0.2
Neuroticism	0.1	0.2	0.4	0.7	0.5	0.0
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.3	0.2	0.5	-0.2
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.1	0.2	0.3	0.2
Angina	0.1	0.2	0.4	0.3	0.6	0.0
Fed-up feelings	0.1	0.2	0.2	0.5	0.5	0.3
Medication: Levothyroxine sodium	0.1	0.2	0.3	0.2	0.5	-0.6
Sitting height	0.1	0.7	1.2	-0.4	-1.1	-0.8
Past tobacco smoking	0.1	0.2	0.4	-0.6	-0.1	-0.6
Nervous feelings	0.1	0.1	0.3	-0.3	-0.5	-0.2
Hearing difficulty/problems with background noise	0.1	0.2	0.4	0.6	-0.4	0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	-0.2	-0.4	-0.2
Qualifications: None of the above	0.1	0.2	0.5	0.4	-0.7	-0.3
Pain all over the body in last month	0.1	0.1	0.1	-0.4	-0.3	-0.4
Diabetes (self-reported)	0.1	0.2	0.5	0.3	0.7	-0.1
Hip circumference	0.1	0.4	0.5	0.5	0.7	0.7
Illnesses of mother	0.1	0.1	0.2	-0.4	-0.3	-0.3
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	-0.2	-0.3	-0.3
Arm fat mass (right)	0.1	0.4	0.7	0.1	0.9	0.7
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.0	0.5	-0.1
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	0.2	0.7	0.4
Age at first live birth	0.1	0.1	0.3	0.2	0.5	0.0
Pulse wave peak to peak time	0.1	0.1	0.2	0.3	0.4	0.4
Angina (self-reported)	0.1	0.1	0.3	0.3	0.6	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.1	-0.3	-0.1	-0.3
Suffer from ‘nerves’	0.1	0.1	0.2	-0.3	-0.5	0.0
Ever had bowel cancer screening	0.1	0.1	0.1	-0.1	-0.4	-0.1
Medication for cholesterol	0.1	0.2	0.3	0.5	0.1	0.5
Arm fat mass (left)	0.1	0.6	1.0	0.3	1.0	0.9
Number of self-reported non-cancer illnesses	0.1	0.1	0.1	-0.1	0.4	-0.3
Mother’s age at death	0.1	0.1	0.3	-0.5	-0.0	-0.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.3	-0.2	0.3
Ever smoked	0.1	0.1	0.3	0.6	-0.1	0.3
Fractured/broken bones in last 5 years	0.1	0.1	0.2	0.0	0.4	0.2
Ever depressed for a whole week	0.1	0.2	0.4	0.3	-0.6	0.3
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	-0.1	-0.3	-0.3
Worry (Nagel 2018)	0.0	0.0	0.0	0.1	-0.0	0.1
Prostate Cancer	0.0	0.0	0.0	0.2	-0.1	-0.2
Crohns Disease (2012)	0.0	0.0	0.1	0.1	0.3	-0.3
Height	0.0	0.4	1.1	1.0	-0.2	0.3
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.1	0.4	0.3	0.0
Lung FEV1/FVC ratio	0.0	0.2	0.2	-0.5	0.1	-0.5
Hair Pigment	0.0	0.1	0.4	-0.1	0.0	-0.6
Tanning	0.0	0.2	0.6	-0.0	0.0	0.8
Supplements: Glucosamine	0.0	0.1	0.1	-0.3	-0.1	-0.4
High blood pressure (mother)	0.0	0.0	0.0	-0.1	-0.2	-0.1
Father’s age at death	0.0	0.1	0.1	-0.2	-0.3	0.1
Worrier / anxious feelings	0.0	0.0	0.0	-0.2	0.2	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	0.1	0.0	-0.1
Standing height	0.0	0.1	0.2	0.4	-0.2	-0.4
Leg fat percentage (right)	0.0	0.1	0.2	-0.4	0.1	0.0
Neck or shoulder pain in last month	0.0	0.0	0.1	-0.3	0.1	-0.1
Medication: Omeprazole	0.0	0.1	0.2	-0.1	-0.1	-0.4
Whole body fat mass	0.0	0.2	0.4	-0.0	0.7	0.4
Knee pain experienced in last month	0.0	0.0	0.1	0.2	-0.1	-0.3
Guilty feelings	0.0	0.0	0.1	0.0	-0.3	0.1
Commuting to job workplace: Public transport	0.0	0.0	0.1	-0.2	0.3	0.1
Medication: Blood pressure	0.0	0.1	0.1	-0.2	0.3	-0.3
Leg fat percentage (left)	0.0	0.1	0.2	-0.4	0.0	0.1
Average weekly beer plus cider intake	0.0	0.0	0.1	-0.0	-0.2	0.3
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.1	0.0	0.3	0.2
Supplements: Calcium	0.0	0.1	0.1	0.2	0.2	0.3

Hub : Genes

LOC100128640

Models

Trait associations