[Hub]/) : Traits : Basal metabolic rate : →

chr1:752,566-3,191,909

Best TWAS P=1.16e-11 · Best GWAS P=6.74e-10 conditioned to 1.87e-08

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RER1	0.06	0.00	blup	359	0.01	8.1e-03	1.2	-5.1	2.9e-07	0.30	0.04	0.11	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC35E2	0.35	0.15	enet	24	0.17	1.0e-20	-6.1	5.5	3.3e-08	-0.71	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-4.9	-6.4	1.8e-10	0.37	0.36	0.18	FALSE
4	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-2.9	-5.5	3.3e-08	0.21	0.14	0.13	TRUE
5	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-5.7	-5.8	6.0e-09	0.85	0.03	0.66	FALSE
6	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-6.2	6.8	1.2e-11	-0.91	0.02	0.66	TRUE
7	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	5.0	5.4	8.1e-08	-0.06	0.11	0.07	FALSE
8	GTEx	Esophagus Mucosa	TMEM52	0.17	0.18	lasso	2	0.20	2.9e-13	-5.6	5.5	3.0e-08	-0.83	0.24	0.76	FALSE
9	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	4.6	5.5	3.7e-08	-0.06	0.90	0.10	TRUE
10	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	5.4	-5.9	4.6e-09	0.94	0.03	0.91	FALSE
11	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.7	-6.1	9.9e-10	0.79	0.05	0.84	FALSE
12	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.8	5.9	3.7e-09	-0.84	0.09	0.91	FALSE
13	GTEx	Nerve Tibial	RP11-181G12.2	0.24	0.22	lasso	5	0.21	3.7e-15	-4.9	5.2	1.9e-07	-0.04	0.87	0.13	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	TMEM52	0.19	0.18	lasso	4	0.14	2.6e-08	5.4	5.7	1.2e-08	-0.92	0.04	0.96	FALSE
15	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.8	5.9	2.9e-09	-0.92	0.04	0.96	FALSE
16	GTEx	Spleen	TMEM52	0.47	0.21	lasso	5	0.22	2.3e-06	-3.7	-5.2	1.7e-07	0.58	0.25	0.35	FALSE
17	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	4.3	6.6	3.7e-11	-0.08	0.57	0.37	TRUE
18	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-4.3	5.8	6.0e-09	-0.70	0.97	0.03	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	MMP23B	0.05	0.04	lasso	2	0.03	1.9e-04	-5.4	-5.4	7.3e-08	0.80	0.07	0.91	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM52	0.02	0.01	blup	37	0.02	6.6e-03	-5.6	5.8	4.9e-09	-0.91	0.01	0.77	FALSE