[Hub]/) : Traits : Basal metabolic rate : ← →

chr6:129,638,583-132,080,991

Best TWAS P=1.16e-60 · Best GWAS P=9.65e-55 conditioned to 0.0396

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
28	GTEx	Thyroid	L3MBTL3	0.40	0.39	enet	9	0.43	2.8e-35	16	16.4	1.2e-60	0.90	0.00	1.00	TRUE
33	ROSMAP	Brain Pre-frontal Cortex	EPB41L2	0.12	0.12	blup	522	0.10	6.5e-13	3	5.4	8.0e-08	-0.01	0.92	0.01	TRUE
13	GTEx	Lung	L3MBTL3	0.37	0.34	lasso	4	0.38	4.1e-30	16	16.3	8.7e-60	0.89	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	L3MBTL3	0.14	0.12	lasso	2	0.15	2.8e-08	16	16.3	2.2e-59	0.90	0.01	0.99	FALSE
14	GTEx	Lung	RP11-73O6.3	0.15	0.08	lasso	5	0.12	2.2e-09	16	16.2	4.3e-59	0.91	0.01	0.99	FALSE
16	GTEx	Pancreas	L3MBTL3	0.32	0.17	lasso	4	0.23	4.4e-10	16	16.2	5.6e-59	0.88	0.00	1.00	FALSE
29	GTEx	Thyroid	RP11-73O6.3	0.18	0.15	lasso	3	0.20	2.3e-15	14	16.2	6.6e-59	0.91	0.02	0.98	FALSE
5	GTEx	Breast Mammary Tissue (Male)	L3MBTL3	0.31	0.24	lasso	6	0.23	5.5e-06	16	16.2	8.5e-59	0.91	0.01	0.96	FALSE
15	GTEx	Nerve Tibial	L3MBTL3	0.30	0.23	lasso	4	0.22	2.3e-15	16	16.1	2.6e-58	0.87	0.00	1.00	FALSE
22	GTEx	Small Intestine Terminal Ileum	L3MBTL3	0.37	0.20	lasso	4	0.17	1.3e-04	16	16.1	4.2e-58	0.86	0.01	0.95	FALSE
1	GTEx	Adipose Subcutaneous	L3MBTL3	0.20	0.08	lasso	4	0.09	1.1e-07	16	16.1	5.4e-58	0.89	0.01	0.99	FALSE
3	GTEx	Breast Mammary Tissue	L3MBTL3	0.31	0.25	lasso	7	0.23	2.8e-12	16	16.1	5.5e-58	0.89	0.00	1.00	FALSE
30	GTEx	Whole Blood	L3MBTL3	0.22	0.20	lasso	9	0.20	5.1e-18	16	16.0	1.6e-57	0.86	0.00	1.00	FALSE
11	GTEx	Colon Transverse	RP11-73O6.3	0.19	0.09	lasso	2	0.06	1.2e-03	16	15.9	3.1e-57	0.88	0.01	0.99	FALSE
23	GTEx	Spleen	L3MBTL3	0.64	0.34	enet	14	0.48	6.4e-14	13	15.9	3.5e-57	0.88	0.02	0.98	FALSE
31	GTEx	Whole Blood	RP11-73O6.3	0.15	0.06	lasso	8	0.04	1.1e-04	16	15.9	4.9e-57	0.85	0.01	0.97	FALSE
10	GTEx	Colon Transverse	L3MBTL3	0.27	0.13	lasso	8	0.20	8.0e-10	16	15.9	1.0e-56	0.87	0.01	0.99	FALSE
4	GTEx	Breast Mammary Tissue	RP11-73O6.3	0.27	0.22	lasso	9	0.22	1.5e-11	16	15.8	1.5e-56	0.85	0.01	0.99	FALSE
19	GTEx	Prostate	L3MBTL3	0.35	0.27	lasso	5	0.17	5.9e-05	16	15.8	2.7e-56	0.87	0.01	0.96	FALSE
21	GTEx	Skin Sun Exposed Lower leg	L3MBTL3	0.25	0.25	lasso	9	0.24	1.4e-19	16	15.8	3.4e-56	0.86	0.00	1.00	FALSE
8	GTEx	Breast Mammary Tissue (Female)	RP11-73O6.3	0.29	0.08	lasso	5	0.10	5.7e-04	13	15.6	4.0e-55	0.85	0.02	0.95	FALSE
7	GTEx	Breast Mammary Tissue (Female)	L3MBTL3	0.30	0.13	lasso	5	0.14	4.5e-05	11	15.6	6.0e-55	0.86	0.01	0.97	FALSE
12	GTEx	Esophagus Mucosa	L3MBTL3	0.26	0.18	lasso	2	0.23	2.7e-15	13	15.5	3.0e-54	0.82	0.01	0.99	FALSE
26	GTEx	Stomach	RP11-73O6.3	0.21	0.12	lasso	6	0.06	5.9e-04	15	15.5	7.4e-54	0.89	0.03	0.88	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	L3MBTL3	0.26	0.12	lasso	4	0.12	4.0e-07	12	15.3	1.3e-52	0.79	0.01	0.99	FALSE
6	GTEx	Breast Mammary Tissue (Male)	RP11-73O6.3	0.33	0.17	lasso	4	0.12	1.3e-03	16	15.0	7.3e-51	0.84	0.02	0.88	FALSE
27	GTEx	Testis	L3MBTL3	0.41	0.22	lasso	8	0.30	9.2e-14	16	14.9	4.4e-50	0.78	0.00	1.00	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	L3MBTL3	0.28	0.08	lasso	10	0.03	4.4e-02	16	14.9	5.2e-50	0.86	0.02	0.91	FALSE
25	GTEx	Stomach	L3MBTL3	0.36	0.18	enet	27	0.20	1.1e-09	15	14.8	1.8e-49	0.85	0.02	0.98	FALSE
24	GTEx	Spleen	RP11-73O6.3	0.45	0.43	enet	21	0.42	7.7e-12	13	14.7	8.9e-49	0.80	0.11	0.89	FALSE
17	GTEx	Pituitary	L3MBTL3	0.45	0.31	lasso	8	0.29	5.1e-08	11	13.7	6.1e-43	0.74	0.03	0.96	FALSE
35	YFS	Blood	L3MBTL3	0.28	0.22	blup	614	0.27	1.2e-88	13	12.6	2.7e-36	0.67	1.00	0.00	FALSE
37	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	L3MBTL3	0.06	0.01	blup	114	0.04	4.0e-03	13	12.6	3.5e-36	0.78	0.05	0.65	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	L3MBTL3	0.14	0.07	blup	609	0.08	3.8e-10	16	12.3	1.1e-34	0.67	0.01	0.99	FALSE
32	METSIM	Adipose	L3MBTL3	0.13	0.12	enet	22	0.12	4.8e-18	13	12.1	1.1e-33	0.68	0.99	0.01	FALSE
18	GTEx	Pituitary	RP11-73O6.3	0.48	0.07	lasso	7	0.16	8.2e-05	11	11.5	1.1e-30	0.62	0.04	0.90	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	L3MBTL3	0.05	0.00	blup	114	0.01	1.0e-02	10	6.6	3.6e-11	0.51	0.02	0.28	FALSE