Best TWAS P=8.04e-23 · Best GWAS P=9.72e-25 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 6.1e-04 | -9.7 | 9.8 | 8.0e-23 | -0.98 | 0.02 | 0.96 | TRUE |
| 2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 1.9e-04 | -5.2 | 7.1 | 1.1e-12 | -0.74 | 0.10 | 0.90 | FALSE |
| 3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 2.6e-03 | -3.6 | -5.9 | 4.0e-09 | 0.41 | 0.34 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NMBR | 0.03 | 0.03 | blup | 46 | 0.02 | 3.6e-05 | 4.6 | -5.4 | 8.4e-08 | 0.13 | 0.88 | 0.04 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | VTA1 | 0.03 | 0.02 | blup | 66 | 0.02 | 1.7e-03 | 5.6 | -5.6 | 2.1e-08 | 0.08 | 0.16 | 0.36 | FALSE |
| 6 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 3.4e-02 | 4.3 | -6.2 | 7.6e-10 | 0.11 | 0.02 | 0.65 | TRUE |