[Hub]/) : Traits : Basal metabolic rate :

chr6:151,030,107-153,695,725

Best TWAS P=7.18e-09 · Best GWAS P=4.19e-24 conditioned to 8.84e-19

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 ROSMAP Brain Pre-frontal Cortex SYNE1 0.12 0.01 blup 875 0.05 6.9e-07 1.1 5.6 2.8e-08 0.26 0.63 0.08 TRUE
2 YFS Blood RMND1 0.06 0.06 lasso 12 0.05 6.5e-16 4.9 -5.4 7.8e-08 -0.01 1.00 0.00 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma RGS17 0.02 0.02 enet 5 0.02 1.8e-04 5.2 -5.2 1.7e-07 0.02 0.01 0.98 TRUE
4 The Cancer Genome Atlas Breast Invasive Carcinoma RMND1 0.02 0.00 blup 57 0.01 3.1e-03 3.9 -5.2 2.6e-07 -0.02 0.00 0.61 FALSE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RMND1 0.16 0.10 lasso 7 0.12 1.6e-06 4.9 -5.6 2.1e-08 -0.02 0.02 0.98 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RMND1 0.07 0.06 blup 58 0.09 1.4e-10 4.9 -5.5 4.3e-08 0.01 0.19 0.81 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma RMND1 0.05 0.06 lasso 2 0.07 4.3e-08 6.1 -5.8 7.2e-09 -0.04 0.00 1.00 TRUE
8 The Cancer Genome Atlas Skin Cutaneous Melanoma RMND1 0.16 0.15 enet 7 0.09 2.7e-03 6.1 -5.4 7.0e-08 -0.04 0.00 0.95 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma RMND1 0.06 0.04 blup 57 0.06 4.9e-05 4.2 -5.6 1.9e-08 -0.03 0.03 0.88 FALSE