[Hub]/) : Traits : Basal metabolic rate :

chr17:39,993,748-41,538,783

Best TWAS P=7.33e-09 · Best GWAS P=1.98e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MLX 0.03 0.03 enet 12 0.02 6.5e-04 -5.6 -5.7 1.1e-08 0.94 0.02 0.97 FALSE
2 GTEx Adipose Subcutaneous TUBG2 0.21 0.18 enet 17 0.26 2.1e-21 -5.4 -5.1 2.7e-07 0.94 0.02 0.98 FALSE
3 GTEx Adipose Subcutaneous HSD17B1P1 0.06 0.09 enet 6 0.09 4.0e-08 -5.3 -5.7 9.7e-09 0.92 0.03 0.97 FALSE
4 GTEx Brain Cerebellum HSD17B1P1 0.17 0.16 lasso 4 0.20 1.7e-06 -5.6 -5.5 3.0e-08 0.95 0.04 0.94 FALSE
5 GTEx Breast Mammary Tissue TUBG2 0.15 0.06 enet 18 0.08 4.5e-05 -5.3 -5.6 1.9e-08 0.94 0.02 0.98 FALSE
6 GTEx Breast Mammary Tissue CNTNAP1 0.06 0.03 lasso 2 0.05 9.9e-04 -5.4 5.5 5.2e-08 -0.98 0.02 0.95 FALSE
7 GTEx Colon Sigmoid TUBG2 0.16 0.04 lasso 5 0.05 6.7e-03 -5.6 -5.4 5.2e-08 0.99 0.02 0.91 FALSE
8 GTEx Colon Transverse HSD17B1P1 0.14 0.11 lasso 4 0.09 3.8e-05 -5.4 -5.2 1.8e-07 0.97 0.04 0.94 FALSE
9 GTEx Esophagus Muscularis HSD17B1P1 0.08 0.03 lasso 3 0.01 6.8e-02 -5.3 -5.4 6.2e-08 0.96 0.04 0.88 FALSE
10 GTEx Heart Atrial Appendage TUBG2 0.07 0.05 lasso 2 0.02 2.9e-02 -5.6 -5.3 1.3e-07 0.98 0.03 0.89 FALSE
11 GTEx Nerve Tibial TUBG2 0.26 0.28 enet 39 0.28 2.2e-20 -5.5 -5.2 1.9e-07 0.92 0.01 0.99 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic TUBG1 0.11 0.01 lasso 6 0.00 1.7e-01 4.4 -5.4 7.4e-08 0.88 0.03 0.77 FALSE
13 GTEx Skin Sun Exposed Lower leg NAGLU 0.08 0.06 enet 9 0.09 5.8e-08 4.0 -5.5 5.0e-08 0.84 0.02 0.97 FALSE
14 GTEx Testis TUBG1 0.12 0.09 enet 18 0.08 1.8e-04 -5.4 -5.1 2.7e-07 0.98 0.02 0.97 FALSE
15 GTEx Thyroid TUBG2 0.19 0.21 lasso 7 0.20 3.5e-15 -5.5 -5.3 1.2e-07 0.98 0.01 0.99 FALSE
16 METSIM Adipose TUBG2 0.08 0.09 lasso 6 0.09 5.2e-13 4.3 -5.2 2.6e-07 0.87 0.03 0.97 FALSE
17 NTR Blood TUBG2 0.01 0.00 blup 247 0.01 4.0e-03 -4.3 5.4 7.7e-08 -0.75 0.13 0.75 FALSE
18 The Cancer Genome Atlas Colon Adenocarcinoma CNTNAP1 0.06 0.05 blup 27 0.03 7.3e-03 -5.5 5.8 7.3e-09 -0.95 0.01 0.95 TRUE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NAGLU 0.13 0.02 enet 8 0.04 1.6e-05 4.0 -5.4 6.5e-08 0.78 0.01 0.87 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TUBG2 0.08 0.05 blup 29 0.07 3.5e-08 -4.4 -5.1 2.8e-07 0.96 0.01 0.98 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma HSD17B1 0.30 0.05 enet 14 0.06 2.8e-07 -5.6 -5.3 1.4e-07 0.88 0.01 0.99 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma CNTNAP1 0.06 0.05 lasso 1 0.04 6.8e-06 -5.4 5.4 8.3e-08 -0.97 0.00 1.00 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma CNTNAP1 0.06 0.04 blup 27 0.04 8.9e-05 -5.4 5.5 4.0e-08 -0.92 0.00 0.99 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma HSD17B1 0.02 0.03 blup 30 0.03 4.0e-04 -5.6 -5.3 9.1e-08 0.98 0.01 0.98 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma CNTNAP1 0.04 0.03 blup 27 0.05 2.7e-05 -5.3 5.5 4.7e-08 -0.89 0.01 0.98 FALSE