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chr19:41,193,580-42,626,207

Best TWAS P=4.87e-10 · Best GWAS P=4.13e-09 conditioned to 0.246

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATP5SL	0.34	0.48	bslmm	365	0.48	1.5e-65	5.6	-5.4	5.5e-08	-0.99	0.01	0.99	FALSE
2	GTEx	Artery Aorta	ATP5SL	0.14	0.00	lasso	2	0.01	1.6e-01	5.4	-5.4	7.6e-08	-0.98	0.02	0.60	FALSE
3	GTEx	Artery Aorta	B3GNT8	0.14	0.09	lasso	2	0.08	2.6e-05	5.8	5.2	2.1e-07	0.97	0.01	0.98	FALSE
4	GTEx	Artery Aorta	CTC-435M10.6	0.16	0.14	lasso	3	0.13	1.3e-07	5.7	5.6	2.2e-08	0.99	0.02	0.98	FALSE
5	GTEx	Brain Cerebellar Hemisphere	B3GNT8	0.38	0.30	lasso	5	0.23	1.1e-06	5.8	5.6	2.1e-08	0.97	0.01	0.98	FALSE
6	GTEx	Brain Cerebellar Hemisphere	CTC-435M10.6	0.29	0.20	lasso	4	0.18	2.6e-05	5.8	5.9	3.8e-09	0.99	0.01	0.97	FALSE
7	GTEx	Brain Cerebellum	B3GNT8	0.28	0.23	lasso	5	0.21	9.2e-07	5.8	5.7	1.4e-08	0.99	0.02	0.98	FALSE
8	GTEx	Brain Cerebellum	CTC-435M10.6	0.18	0.01	lasso	4	0.03	5.1e-02	5.6	5.9	4.2e-09	0.88	0.02	0.86	FALSE
9	GTEx	Brain Frontal Cortex BA9	ATP5SL	0.28	0.15	lasso	3	0.10	1.0e-03	5.4	-5.4	6.3e-08	-0.98	0.02	0.93	FALSE
10	GTEx	Cells Transformed fibroblasts	B3GNT8	0.10	0.02	lasso	2	0.03	2.0e-03	5.4	5.4	5.9e-08	0.98	0.03	0.97	FALSE
11	GTEx	Cells Transformed fibroblasts	CTC-435M10.6	0.18	0.16	lasso	2	0.15	4.2e-11	5.4	5.2	2.5e-07	0.96	0.02	0.98	FALSE
12	GTEx	Colon Transverse	B3GNT8	0.21	0.17	lasso	4	0.18	6.7e-09	5.4	5.4	8.5e-08	0.97	0.03	0.97	FALSE
13	GTEx	Esophagus Muscularis	CTC-435M10.6	0.12	0.12	lasso	2	0.10	1.4e-06	5.3	5.2	2.0e-07	0.95	0.02	0.98	FALSE
14	GTEx	Lung	CTC-435M10.6	0.13	0.11	lasso	3	0.10	3.3e-08	5.4	5.4	6.4e-08	0.98	0.03	0.97	FALSE
15	GTEx	Muscle Skeletal	EXOSC5	0.07	0.03	enet	6	0.03	4.1e-04	5.6	5.5	4.9e-08	0.98	0.01	0.98	FALSE
16	GTEx	Nerve Tibial	CTC-435M10.6	0.18	0.15	lasso	6	0.14	5.5e-10	5.3	5.5	4.1e-08	0.98	0.02	0.98	FALSE
17	GTEx	Stomach	B3GNT8	0.22	0.14	lasso	7	0.12	1.4e-06	5.4	5.4	7.6e-08	0.97	0.02	0.98	FALSE
18	GTEx	Testis	EXOSC5	0.31	0.33	enet	10	0.33	1.8e-15	5.4	5.5	3.5e-08	0.99	0.02	0.98	FALSE
19	GTEx	Thyroid	EXOSC5	0.14	0.08	lasso	5	0.05	8.4e-05	5.5	5.2	2.2e-07	0.97	0.03	0.95	FALSE
20	YFS	Blood	ATP5SL	0.06	0.02	lasso	12	0.03	1.1e-09	5.8	5.5	3.1e-08	0.85	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	B3GNT8	0.03	0.04	blup	20	0.04	3.2e-04	5.4	5.4	5.8e-08	0.99	0.01	0.96	FALSE
22	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	BCKDHA	0.02	0.02	lasso	2	0.02	1.5e-02	5.6	-5.5	3.0e-08	-0.99	0.01	0.81	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	B3GNT8	0.04	0.07	blup	20	0.07	1.2e-13	5.4	5.3	1.3e-07	0.98	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATP5SL	0.02	0.03	enet	4	0.02	7.0e-04	5.6	-5.5	3.3e-08	-0.99	0.02	0.89	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	EXOSC5	0.04	0.03	lasso	2	0.02	5.8e-03	5.8	5.6	2.1e-08	0.95	0.01	0.77	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ATP5SL	0.23	0.05	blup	18	0.05	4.5e-03	5.9	-6.2	7.3e-10	-0.90	0.01	0.85	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	ATP5SL	0.03	0.03	blup	18	0.03	4.1e-04	5.9	-5.6	1.8e-08	-0.99	0.01	0.93	FALSE
28	The Cancer Genome Atlas	Rectum Adenocarcinoma	B3GNT8	0.39	0.08	blup	20	0.07	1.1e-02	5.6	6.2	4.9e-10	0.85	0.00	0.30	TRUE
29	The Cancer Genome Atlas	Thyroid Carcinoma	ATP5SL	0.02	0.02	blup	18	0.02	3.5e-03	5.9	-5.5	3.4e-08	-0.99	0.01	0.82	FALSE