[Hub]/) : Traits : Basal metabolic rate : ← →

chr1:22,197,336-24,216,118

Best TWAS P=4.44e-13 · Best GWAS P=2.62e-12 conditioned to 0.0487

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HTR1D 0.11 0.07 enet 21 0.09 1.1e-10 -4.8 5.8 6.1e-09 -0.78 0.53 0.47 FALSE
2 GTEx Brain Cortex LUZP1 0.23 0.14 lasso 5 0.10 7.8e-04 -6.9 6.9 4.1e-12 -1.00 0.02 0.78 FALSE
3 GTEx Brain Frontal Cortex BA9 RP1-184J9.2 0.38 0.00 lasso 11 0.00 4.3e-01 -6.7 5.4 8.5e-08 -0.54 0.04 0.38 FALSE
4 GTEx Cells Transformed fibroblasts LUZP1 0.09 0.09 lasso 4 0.08 2.8e-06 -6.9 6.9 4.5e-12 -1.00 0.01 0.99 FALSE
5 GTEx Muscle Skeletal LUZP1 0.07 0.08 enet 14 0.08 3.5e-08 2.9 5.2 1.7e-07 -0.62 0.09 0.91 FALSE
6 GTEx Skin Sun Exposed Lower leg KDM1A 0.09 0.01 lasso 5 0.01 1.1e-01 -6.7 -5.2 2.5e-07 0.39 0.03 0.81 FALSE
7 GTEx Testis LUZP1 0.17 0.09 lasso 4 0.08 2.6e-04 -6.7 -6.5 5.8e-11 0.55 0.02 0.91 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma WNT4 0.03 0.01 blup 72 0.02 3.8e-05 4.1 5.8 8.0e-09 -0.04 0.26 0.48 TRUE
9 The Cancer Genome Atlas Colon Adenocarcinoma HTR1D 0.10 0.07 enet 7 0.08 3.8e-05 -5.6 6.4 1.6e-10 -0.94 0.02 0.98 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma HTR1D 0.24 0.12 lasso 4 0.12 1.2e-05 -6.8 7.2 4.4e-13 -0.76 0.01 0.98 TRUE
11 The Cancer Genome Atlas Rectum Adenocarcinoma HTR1D 0.19 0.12 enet 11 0.13 7.3e-04 -7.0 6.4 1.9e-10 -0.94 0.01 0.90 FALSE