[Hub]/) : Traits : Basal metabolic rate : ← →

chr2:217,456,567-220,226,393

Best TWAS P=3.63e-16 · Best GWAS P=7.42e-30 conditioned to 6.34e-13

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Thyroid Carcinoma	DIRC3	0.08	0.06	lasso	5	0.07	2.7e-07	-8.8	8.2	3.6e-16	-0.56	0.98	0.01	TRUE
6	ROSMAP	Brain Pre-frontal Cortex	DIRC3	0.12	0.07	bslmm	697	0.08	2.7e-10	-6.6	7.2	5.2e-13	0.00	1.00	0.00	TRUE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DIRC3	0.12	0.01	blup	275	0.02	3.3e-03	-1.4	6.5	1.1e-10	-0.51	0.05	0.52	TRUE
2	GTEx	Adipose Visceral Omentum	PNKD	0.11	0.00	enet	31	0.00	2.3e-01	-5.7	6.1	9.4e-10	0.06	0.01	0.92	TRUE
4	GTEx	Pituitary	PNKD	0.29	0.23	enet	21	0.24	8.9e-07	-5.7	5.6	2.2e-08	0.09	0.01	0.98	FALSE
5	METSIM	Adipose	PNKD	0.07	0.08	lasso	7	0.08	4.8e-12	-5.7	5.6	2.6e-08	0.07	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	BCS1L	0.06	0.01	enet	9	0.04	2.3e-04	-3.0	5.6	2.7e-08	-0.04	0.07	0.24	FALSE
3	GTEx	Pancreas	PNKD	0.12	0.10	lasso	3	0.08	3.6e-04	-5.7	5.3	1.4e-07	0.05	0.00	0.97	FALSE
7	YFS	Blood	PNKD	0.08	0.07	lasso	6	0.09	2.9e-27	-3.9	5.2	2.5e-07	0.05	0.04	0.95	FALSE