Best TWAS P=6.77e-10 · Best GWAS P=2.46e-09 conditioned to 0.000866
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | METTL21A | 0.10 | 0.02 | lasso | 4 | 0.02 | 1.6e-02 | -4.6 | 5.5 | 4.8e-08 | 0.32 | 0.21 | 0.12 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | CREB1 | 0.15 | 0.00 | enet | 7 | 0.00 | 2.8e-01 | -4.6 | -6.2 | 6.8e-10 | -0.50 | 0.13 | 0.44 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAM119A | 0.04 | 0.02 | blup | 51 | 0.03 | 1.0e-06 | -4.5 | 5.2 | 1.9e-07 | 0.64 | 0.03 | 0.95 | FALSE |