[Hub]/) : Traits : Basal metabolic rate : ← →

chr3:37,692,342-39,280,382

Best TWAS P=1.57e-10 · Best GWAS P=2.97e-09 conditioned to 0.658

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ACVR2B	0.08	0.08	enet	15	0.09	9.6e-11	-4.7	5.3	9.7e-08	-0.88	0.11	0.89	FALSE
2	GTEx	Adipose Subcutaneous	EXOG	0.10	0.00	enet	12	0.00	1.3e-01	-5.9	-5.5	5.1e-08	0.68	0.02	0.76	FALSE
3	GTEx	Brain Cerebellum	EXOG	0.19	0.23	enet	4	0.21	7.7e-07	-5.9	-5.9	3.6e-09	0.99	0.02	0.98	FALSE
4	GTEx	Brain Cerebellum	ACVR2B-AS1	0.25	0.07	lasso	6	0.10	8.3e-04	-5.8	-5.8	6.6e-09	0.91	0.02	0.95	FALSE
5	GTEx	Brain Frontal Cortex BA9	EXOG	0.18	0.08	lasso	4	0.05	1.7e-02	-5.9	-5.9	4.6e-09	0.99	0.02	0.88	FALSE
6	GTEx	Breast Mammary Tissue	EXOG	0.08	0.06	enet	10	0.05	8.6e-04	-5.1	-6.4	1.6e-10	0.90	0.03	0.95	TRUE
7	GTEx	Colon Transverse	XYLB	0.08	0.03	enet	15	0.05	1.7e-03	-5.9	5.9	3.7e-09	-0.85	0.03	0.94	FALSE
8	GTEx	Esophagus Mucosa	EXOG	0.13	0.05	lasso	3	0.03	5.0e-03	-5.9	-6.0	1.6e-09	0.98	0.02	0.95	FALSE
9	GTEx	Ovary	EXOG	0.33	0.25	lasso	8	0.21	8.1e-06	-5.4	-5.7	1.1e-08	0.90	0.05	0.83	FALSE
10	GTEx	Pancreas	EXOG	0.22	0.08	enet	15	0.03	2.6e-02	-5.9	-5.2	1.5e-07	0.91	0.03	0.94	FALSE
11	GTEx	Stomach	EXOG	0.14	0.05	lasso	6	0.02	2.5e-02	-5.9	-5.9	3.5e-09	1.00	0.02	0.96	FALSE
12	GTEx	Testis	EXOG	0.35	0.28	lasso	5	0.26	8.1e-12	-5.9	-6.0	2.0e-09	1.00	0.01	0.99	FALSE
13	GTEx	Thyroid	EXOG	0.19	0.20	lasso	3	0.19	2.9e-14	-5.8	-5.8	6.1e-09	0.98	0.02	0.98	FALSE
14	NTR	Blood	ACVR2B	0.02	0.02	lasso	3	0.02	5.6e-07	-5.4	-5.7	1.3e-08	0.95	0.04	0.96	FALSE
15	NTR	Blood	EXOG	0.02	0.03	lasso	6	0.03	1.0e-09	-4.7	5.1	3.0e-07	-0.89	0.11	0.89	FALSE
16	NTR	Blood	XYLB	0.05	0.06	lasso	3	0.06	6.2e-18	-5.4	-5.5	5.1e-08	0.87	0.17	0.83	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	EXOG	0.10	0.13	lasso	2	0.12	4.8e-15	-5.8	-5.4	5.5e-08	0.98	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EXOG	0.14	0.09	blup	56	0.09	9.5e-06	-5.8	-5.5	3.4e-08	0.88	0.01	0.98	FALSE
19	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC100128640	0.09	0.05	lasso	2	0.03	1.7e-02	-5.4	5.4	6.9e-08	-0.86	0.02	0.51	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EXOG	0.02	0.02	blup	56	0.01	1.0e-02	-5.6	-5.7	1.2e-08	0.96	0.02	0.86	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	XYLB	0.05	0.03	lasso	4	0.02	2.4e-03	-5.3	5.4	8.0e-08	-0.93	0.02	0.97	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC100128640	0.08	0.02	blup	28	0.03	2.6e-04	-5.9	5.2	1.6e-07	-0.87	0.01	0.97	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	ACVR2B	0.02	0.00	blup	49	0.01	1.6e-02	-5.6	5.6	2.3e-08	-0.92	0.03	0.50	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100128640	0.07	0.03	blup	28	0.03	1.0e-03	-5.9	5.5	4.4e-08	-0.96	0.01	0.98	FALSE