[Hub]/) : Traits : Basal metabolic rate : ← →

chr3:153,142,317-154,733,231

Best TWAS P=4.58e-13 · Best GWAS P=1.17e-11 conditioned to 0.122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -5.6 -6.3 3.4e-10 -0.49 0.89 0.11 FALSE
2 GTEx Adipose Subcutaneous ARHGEF26 0.10 0.06 enet 8 0.07 2.2e-06 -5.7 5.7 9.5e-09 0.39 0.86 0.12 FALSE
3 GTEx Artery Tibial ARHGEF26 0.11 0.12 enet 12 0.12 5.9e-10 -5.6 5.3 1.2e-07 0.36 0.92 0.08 FALSE
4 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 6.8 7.2 4.6e-13 0.81 0.03 0.76 TRUE
5 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -5.5 6.5 7.5e-11 0.48 0.88 0.12 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic ARHGEF26 0.13 0.11 lasso 4 0.07 6.8e-05 -5.5 6.1 1.1e-09 0.45 0.76 0.20 FALSE
7 GTEx Skin Sun Exposed Lower leg ARHGEF26 0.10 0.08 enet 12 0.11 2.9e-09 -5.6 5.3 1.5e-07 0.33 0.92 0.08 FALSE
8 GTEx Spleen DHX36 0.39 0.09 enet 21 0.34 2.1e-09 -3.1 -5.5 4.5e-08 -0.65 0.19 0.79 FALSE
9 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -5.7 6.1 1.2e-09 0.44 0.75 0.19 FALSE
10 METSIM Adipose ARHGEF26 0.07 0.08 lasso 6 0.07 3.5e-11 -5.6 5.8 6.9e-09 0.45 0.91 0.09 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -5.4 6.4 2.1e-10 0.50 0.31 0.59 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -4.9 -5.5 2.9e-08 -0.51 0.99 0.01 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma DHX36 0.05 0.00 enet 9 0.01 1.0e-01 -4.1 -5.2 1.7e-07 -0.76 0.01 0.64 FALSE