TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Basal metabolic rate
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chr3:171,064,766-172,924,003
Best TWAS P=8.82e-17 · Best GWAS P=2.65e-22 conditioned to 3.27e-08
171M
171.5M
172M
172.5M
173M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
FNDC3B
0.07
0.06
enet
8
0.05
3.2e-07
-8.80
8.3
8.8e-17
0.04
0.88
0.10
TRUE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
FNDC3B
0.07
0.02
enet
6
0.02
3.9e-03
6.52
-6.8
1.1e-11
-0.83
0.01
0.98
TRUE
3
YFS
Blood
TNFSF10
0.09
0.04
bslmm
462
0.08
1.6e-24
6.44
6.3
2.2e-10
0.38
1.00
0.00
TRUE
2
GTEx
Ovary
TNFSF10
0.40
0.01
lasso
10
0.05
1.8e-02
0.75
5.3
9.4e-08
0.41
0.03
0.48
TRUE