Best TWAS P=1.24e-08 · Best GWAS P=6.63e-09 conditioned to 0.0356
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | DPY19L1 | 0.08 | 0.05 | enet | 11 | 0.06 | 4.4e-08 | -5.2 | -5.7 | 1.2e-08 | 0.79 | 0.12 | 0.88 | TRUE |
2 | GTEx | Skin Not Sun Exposed Suprapubic | DPY19L1 | 0.12 | 0.01 | lasso | 8 | 0.05 | 9.5e-04 | -5.8 | 5.5 | 3.7e-08 | -0.93 | 0.01 | 0.98 | FALSE |
3 | GTEx | Skin Sun Exposed Lower leg | DPY19L1 | 0.15 | 0.07 | lasso | 7 | 0.05 | 5.7e-05 | -5.7 | 5.6 | 2.4e-08 | -0.97 | 0.01 | 0.99 | FALSE |
4 | ROSMAP | Brain Pre-frontal Cortex | DPY19L1 | 0.06 | 0.07 | lasso | 2 | 0.06 | 8.1e-08 | -5.2 | -5.2 | 2.4e-07 | 0.65 | 0.17 | 0.83 | FALSE |