Best TWAS P=1.07e-08 · Best GWAS P=7.65e-07 conditioned to 0.877
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | LINC00957 | 0.25 | 0.11 | lasso | 5 | 0.19 | 1.2e-05 | 4.9 | -5.3 | 1.1e-07 | -0.86 | 0.02 | 0.94 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | POLR2J4 | 0.01 | 0.00 | blup | 49 | 0.01 | 5.9e-03 | -4.4 | 5.7 | 1.1e-08 | 0.85 | 0.01 | 0.38 | TRUE |