TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of whole body
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chr7:45,255,940-46,658,015
Best TWAS P=4.75e-08 · Best GWAS P=4.34e-21 conditioned to 5.62e-18
45.2M
45.4M
45.6M
45.8M
46M
46.2M
46.4M
46.6M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Sun Exposed Lower leg
IGFBP3
0.09
0
lasso
6
0
0.27
4.3
5.5
4.8e-08
0.17
0.14
0.06
TRUE