TWAS hub - POLR2J4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2030	0.0410	5.6e-15	0.139	0.121	0.139	0.120	0.116	1.3e-16	1.4e-14	1.3e-16	1.8e-14	5.9e-14
2	GTEx	Adipose Visceral Omentum	0.2020	0.0610	3.1e-05	0.037	NA	0.065	NA	0.075	5.3e-03	NA	2.9e-04	NA	1.0e-04
3	GTEx	Artery Tibial	0.0770	0.0357	9.3e-03	0.023	NA	0.007	NA	0.023	6.1e-03	NA	9.1e-02	NA	6.4e-03
4	GTEx	Brain Cerebellum	0.2610	0.0910	1.5e-04	0.034	NA	0.072	NA	0.051	3.5e-02	NA	3.7e-03	NA	1.3e-02
5	GTEx	Breast Mammary Tissue	0.1190	0.0540	9.8e-03	0.047	NA	0.053	NA	0.054	2.0e-03	NA	1.0e-03	NA	8.9e-04
6	GTEx	Breast Mammary Tissue (Female)	0.1081	0.0602	3.4e-02	0.003	NA	0.009	NA	0.004	2.5e-01	NA	1.7e-01	NA	2.3e-01
7	GTEx	Cells Transformed fibroblasts	0.1740	0.0500	3.8e-06	0.068	NA	0.067	NA	0.075	8.2e-06	NA	1.0e-05	NA	2.7e-06
8	GTEx	Colon Sigmoid	0.1980	0.0720	3.0e-03	0.021	NA	-0.007	NA	0.036	5.8e-02	NA	7.5e-01	NA	2.0e-02
9	GTEx	Esophagus Gastroesophageal Junction	0.2130	0.0700	1.4e-03	0.025	NA	0.029	NA	0.006	4.2e-02	NA	3.2e-02	NA	1.9e-01
10	GTEx	Esophagus Mucosa	0.2690	0.0650	9.2e-07	0.086	NA	0.163	NA	0.158	2.4e-06	NA	5.0e-11	NA	9.6e-11
11	GTEx	Esophagus Muscularis	0.1820	0.0480	2.0e-07	0.076	NA	0.149	NA	0.144	2.4e-05	NA	2.6e-09	NA	4.6e-09
12	GTEx	Heart Atrial Appendage	0.3070	0.0700	8.7e-07	0.149	NA	0.136	NA	0.127	3.2e-07	NA	1.1e-06	NA	2.5e-06
13	GTEx	Liver	0.3480	0.1030	5.1e-04	0.147	NA	0.102	NA	0.091	6.9e-05	NA	8.8e-04	NA	1.7e-03
14	GTEx	Lung	0.0998	0.0419	1.0e-03	0.023	NA	0.052	NA	0.037	6.2e-03	NA	8.0e-05	NA	7.5e-04
15	GTEx	Nerve Tibial	0.3013	0.0664	1.4e-07	0.053	NA	0.092	NA	0.109	1.3e-04	NA	4.8e-07	NA	4.3e-08
16	GTEx	Pituitary	0.2540	0.0900	3.2e-04	0.213	NA	0.105	NA	0.178	4.6e-06	NA	1.4e-03	NA	3.1e-05
17	GTEx	Skin Sun Exposed Lower leg	0.3570	0.0640	2.4e-12	0.191	NA	0.206	NA	0.205	9.9e-16	NA	6.8e-17	NA	7.1e-17
18	GTEx	Spleen	0.2860	0.0860	3.5e-04	0.206	NA	0.180	NA	0.211	5.3e-06	NA	2.3e-05	NA	4.0e-06
19	GTEx	Stomach	0.2120	0.0660	6.8e-05	0.038	NA	0.094	NA	0.094	6.5e-03	NA	3.0e-05	NA	2.9e-05
20	GTEx	Thyroid	0.2470	0.0500	2.6e-11	0.147	NA	0.165	NA	0.164	2.3e-11	NA	1.3e-12	NA	1.5e-12
21	ROSMAP	Brain Pre-frontal Cortex	0.0598	0.0245	9.8e-04	0.010	0.034	0.037	0.036	0.021	1.5e-02	3.0e-05	1.5e-05	1.6e-05	8.6e-04
22	TCGA	Breast Invasive Carcinoma	0.0116	0.0077	8.2e-03	-0.001	0.008	0.005	NA	0.003	6.5e-01	5.9e-03	2.7e-02	NA	5.4e-02
23	TCGA	Brain Lower Grade Glioma	0.0330	0.0195	2.2e-03	0.023	0.013	0.013	NA	0.017	1.0e-03	1.0e-02	1.1e-02	NA	3.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Had other major operations	3.6	4.4	8.5	2.6	1.5	2.0	2.4	2.5	2.3	2.5	1.0	2.4	1.3	2.1	1.8	1.8	2.6	2.9	2.2	2.4	2.2	2.2	1.4	0.7	1.7	2.4
Father’s age at death	3.5	4.7	18.5	2.0	1.7	1.3	4.3	2.2	2.4	1.5	2.3	2.4	1.3	2.8	2.0	2.2	2.3	2.5	2.0	2.4	1.6	1.9	1.5	2.3	1.0	1.8
Diabetes (mother)	3.3	4.2	6.9	2.4	2.6	2.6	-0.4	0.9	1.4	2.2	2.5	2.3	2.6	2.3	2.3	2.0	2.3	1.7	1.6	0.7	2.6	2.1	2.2	-1.7	1.9	1.5
Impedance of arm (left)	3.1	14.5	31.6	4.3	5.0	4.3	2.6	0.7	1.4	4.0	4.3	4.6	1.2	4.9	2.6	4.3	5.2	4.9	3.4	1.4	3.8	3.8	2.8	0.2	5.6	4.6
Pulse wave Arterial Stiffness index	2.9	3.4	5.9	1.9	2.0	1.6	2.1	1.6	1.8	1.7	2.0	2.3	0.7	2.4	2.2	2.0	2.2	2.1	2.0	1.3	1.8	1.8	1.4	1.6	1.8	1.6
Age at last live birth	2.8	4.0	7.0	1.7	1.6	1.7	2.1	2.4	2.6	1.9	1.9	2.0	2.0	2.0	2.3	2.6	2.3	2.0	2.5	2.0	2.1	2.4	1.6	1.4	0.7	1.0
Supplements: Calcium	2.8	3.0	7.5	-1.9	-1.9	-1.8	-0.6	-1.0	-1.8	-2.0	-2.0	-2.2	-1.0	-2.3	-1.8	-1.5	-2.0	-1.5	-2.5	-0.3	-2.0	-2.7	-1.9	-0.4	-1.4	-0.8
Impedance of arm (right)	2.7	12.7	30.3	4.0	5.0	4.3	2.1	0.1	1.0	3.7	4.2	4.2	1.0	4.5	2.4	4.1	4.8	4.5	2.7	0.9	3.6	3.4	2.8	-0.1	5.5	4.6
Impedance of whole body	2.6	13.0	32.7	4.0	4.9	4.3	2.1	-0.2	1.0	3.9	3.9	4.3	0.8	4.5	2.4	4.2	4.8	4.7	2.8	0.5	3.6	3.3	2.7	-0.6	5.7	4.8
Myopia	2.5	3.6	17.1	1.6	-0.1	0.2	3.0	4.1	3.2	1.1	0.3	1.4	1.6	1.2	2.8	0.8	1.2	1.8	2.1	3.4	1.1	1.3	1.5	1.4	-0.4	0.5
Tinnitus: Yes, but not now, but have in the past	2.4	2.6	5.1	1.8	1.3	1.4	1.4	1.6	1.6	1.8	1.6	2.1	0.6	1.9	1.4	1.6	2.0	2.2	2.3	1.3	1.6	1.6	0.8	0.3	1.6	1.5
Financial difficulties in last 2 years	2.4	3.3	5.8	-2.3	-2.2	-1.8	-0.4	-1.2	-1.2	-1.9	-2.2	-2.0	-0.9	-2.0	-1.6	-1.8	-2.3	-2.4	-1.5	-1.5	-1.8	-1.8	-2.1	-0.8	-2.0	-2.0
Time employed in main current job	2.4	2.8	13.8	1.1	0.1	0.1	3.7	1.9	3.3	0.7	0.8	1.8	-1.3	2.0	2.3	1.0	1.7	1.4	3.0	0.3	0.5	1.4	0.4	1.5	0.5	-0.0
Pulse wave peak to peak time	2.4	2.9	5.2	-1.6	-1.9	-1.4	-1.8	-1.4	-1.6	-1.4	-1.9	-2.1	-0.6	-2.3	-2.1	-1.9	-2.0	-1.9	-1.7	-1.2	-1.6	-1.6	-1.3	-1.6	-1.7	-1.4
Eye problems/disorders: Glaucoma	2.4	2.8	8.1	-1.6	-0.4	-0.7	-2.7	-2.9	-2.2	-1.2	-0.8	-1.5	-1.8	-1.2	-2.3	-1.1	-1.6	-1.7	-1.8	-2.3	-1.3	-1.2	-1.6	-2.3	-0.1	-0.7
Ever taken oral contraceptive pill	2.3	2.6	5.2	2.0	0.8	1.4	2.3	1.7	1.9	1.7	0.9	1.9	0.2	1.5	2.0	1.2	2.2	2.0	2.0	0.8	1.8	1.4	1.6	1.0	1.6	1.2
Coronary Artery Disease (CAD)	2.2	2.6	7.2	1.8	2.6	2.2	-0.3	-0.0	-0.4	1.9	1.0	1.6	1.3	1.7	1.0	1.1	1.6	1.8	0.6	1.3	1.9	1.2	1.8	-1.2	2.5	2.7
Number of full brothers	2.2	2.7	6.2	1.6	1.1	1.4	0.7	2.3	2.2	1.7	1.9	1.7	2.1	1.7	1.4	1.0	1.4	1.5	1.9	1.7	1.9	2.5	1.8	1.4	0.5	0.8
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.6	6.1	-1.6	-1.4	-1.8	-2.0	-0.9	-1.5	-2.0	-0.3	-1.9	-0.9	-1.8	-1.7	-1.6	-1.6	-2.0	-1.4	-0.8	-1.8	-1.5	-1.7	-0.1	-1.8	-2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.5	10.0	2.4	2.8	2.4	1.8	2.0	0.8	2.4	1.5	2.2	2.9	2.6	1.2	1.5	1.9	2.1	0.7	3.2	2.2	2.0	2.6	0.2	1.6	2.9
Waist Hip Ratio (WHR)	2.0	8.9	17.1	3.5	4.1	3.0	3.8	2.4	1.5	2.9	2.9	3.1	2.3	3.9	2.8	2.5	3.2	3.8	1.3	3.4	2.9	2.4	2.2	1.0	2.8	4.1
Impedance of leg (right)	2.0	9.9	27.2	3.2	4.4	4.0	1.1	-0.9	0.2	3.6	3.2	3.5	0.7	3.7	2.3	3.9	3.9	4.0	1.9	-0.3	3.1	2.5	2.6	-1.6	5.2	4.7
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	6.3	2.0	1.4	1.2	2.4	2.1	1.4	1.0	1.3	1.6	1.7	1.9	1.2	1.1	1.8	1.6	1.0	2.5	1.6	1.0	1.5	0.6	0.9	1.0
Age at first live birth	2.0	3.6	6.8	1.6	1.5	1.3	2.4	2.2	2.3	2.0	1.4	2.1	1.0	2.1	2.6	1.9	2.0	2.2	2.6	1.8	1.9	2.3	1.6	0.7	1.1	1.4
Number of operations (self-reported)	2.0	3.0	8.6	2.0	1.9	2.4	1.2	1.2	0.8	2.2	0.8	1.6	2.2	1.7	1.0	1.8	1.8	2.4	0.5	2.1	1.7	0.9	1.8	-0.1	1.4	2.9
Alcohol drinker status: Never	1.9	2.3	4.8	1.5	1.6	1.4	0.3	1.6	1.1	1.6	1.7	1.6	2.2	1.7	1.4	1.5	1.2	1.3	0.9	1.8	1.8	1.8	2.2	0.7	1.1	1.4
Impedance of leg (left)	1.8	8.7	25.3	3.0	4.0	3.8	1.0	-1.1	0.1	3.5	2.9	3.3	0.5	3.3	1.9	3.5	3.7	3.9	1.8	-0.6	2.9	2.4	2.3	-1.4	5.0	4.5
Medication: Lansoprazole	1.7	1.9	4.6	1.3	0.2	0.9	2.1	1.9	1.9	1.9	0.0	1.7	1.2	1.4	1.0	0.3	1.3	2.0	2.2	1.1	1.1	2.0	0.6	-0.5	0.4	1.3
Eye problems/disorders: None of the above	1.7	2.0	4.9	1.9	1.3	1.4	1.9	1.7	0.7	1.0	-0.4	1.0	2.2	1.1	1.9	0.9	1.2	1.3	-0.0	2.2	1.6	0.7	2.2	0.3	0.6	1.4
Basal cell carcinoma (self-reported)	1.7	2.1	4.1	-1.2	-1.5	-0.9	-1.5	-1.1	-1.9	-0.9	-1.6	-1.9	-0.0	-1.8	-1.5	-1.8	-1.9	-1.4	-1.7	-0.4	-1.1	-2.0	-0.9	-1.5	-1.1	-1.0
Relative age voice broke	1.6	2.4	8.1	1.6	2.4	1.9	0.8	0.1	0.6	1.6	2.9	1.4	1.2	1.7	0.7	1.9	1.6	1.7	0.0	1.0	1.5	0.7	1.8	1.7	1.6	2.0
Tense / ‘highly strung’	1.6	2.7	5.2	-1.9	-1.8	-2.3	0.1	-0.0	-0.6	-2.2	-0.5	-2.0	-1.5	-1.9	-2.1	-1.3	-1.9	-1.6	-1.7	-0.1	-2.2	-1.7	-1.9	1.0	-2.1	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	8.5	1.3	1.4	2.4	-0.9	-0.3	-0.5	1.6	0.7	0.6	2.9	0.3	-0.5	0.9	0.6	1.0	-1.1	0.6	1.3	0.3	1.9	-0.7	0.9	2.5
Illnesses of father: High blood pressure	1.6	2.0	4.0	-1.4	-0.8	-1.3	-1.5	-1.7	-1.4	-1.8	-0.0	-1.4	-0.9	-1.2	-1.8	-1.5	-1.4	-1.7	-1.4	-1.4	-1.6	-2.0	-2.0	-0.2	-1.2	-1.3
Frequency of depressed mood in last 2 weeks	1.5	2.1	7.9	1.2	-1.1	-0.4	2.8	2.8	2.8	0.3	0.7	0.8	0.3	0.6	1.0	0.5	1.1	1.1	2.7	1.6	0.3	0.9	-0.0	2.2	-1.0	-0.7
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	4.6	-1.7	-1.6	-1.9	0.7	1.0	0.3	-1.3	-1.8	-1.1	-0.5	-0.7	-0.6	-1.7	-1.6	-1.4	-0.2	0.4	-1.3	-0.5	-2.1	-0.6	-2.1	-2.1
Prospective memory result	1.5	1.9	5.6	1.5	2.0	1.9	-0.8	0.4	-0.3	1.4	2.4	1.4	1.8	1.4	0.8	1.4	1.2	0.9	0.2	1.2	1.8	0.8	1.2	1.1	1.6	1.4
Glaucoma (self-reported)	1.5	1.7	7.9	-1.2	-0.1	-0.4	-2.8	-1.9	-1.9	-0.8	-0.3	-1.1	-0.6	-0.8	-1.7	-0.9	-1.4	-1.5	-1.5	-1.1	-0.7	-0.8	-1.1	-2.4	-0.1	-0.5
Diabetes diagnosed by doctor	1.5	2.5	7.2	1.6	1.0	1.8	0.4	1.1	1.8	2.2	1.9	2.0	1.1	1.7	1.6	1.6	2.0	1.4	2.7	0.3	2.1	1.8	1.0	-0.7	1.7	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	6.6	-0.5	-2.3	-1.6	2.6	1.4	1.6	-1.0	-1.2	-0.4	-1.5	-0.6	-0.2	0.2	0.0	-0.2	1.5	0.2	-1.1	-0.7	-1.9	1.7	-1.6	-1.9
Alcohol intake versus 10 years previously	1.4	2.1	5.7	-1.4	-0.5	-0.7	-2.4	-0.5	-1.9	-0.7	-0.4	-1.6	1.4	-1.2	-1.4	-2.0	-2.2	-1.9	-1.7	0.6	-1.0	-1.6	-1.2	-1.9	-1.6	-0.9
Shortness of breath walking on level ground	1.4	1.6	5.4	-1.3	-1.6	-1.8	0.9	1.4	0.3	-1.4	-1.0	-0.9	0.4	-0.7	-1.3	-0.2	-1.0	-1.1	0.3	1.2	-1.1	-0.4	-2.1	0.9	-2.3	-2.3
Medication: Seretide 50 evohaler	1.4	1.6	4.4	-1.1	-0.1	-0.7	-1.9	-1.2	-1.9	-1.2	-1.1	-1.3	0.3	-0.9	-1.7	-0.9	-1.6	-1.8	-2.1	-0.1	-0.7	-1.0	-1.2	-1.2	-1.1	-1.1
Knee pain experienced in last month	1.4	2.1	6.1	-1.3	-1.9	-1.4	-0.1	0.2	-0.5	-1.7	-0.6	-1.4	-0.5	-1.4	-2.5	-1.2	-1.0	-1.7	-0.7	-0.1	-1.5	-2.0	-2.4	0.5	-2.0	-2.4
Osteoporosis (self-reported)	1.4	1.8	10.3	-1.1	-1.3	-0.1	-1.7	-0.9	-0.9	-0.4	-3.1	-1.4	0.6	-1.7	-0.4	-0.1	-1.5	-1.1	-1.5	-0.5	-0.6	-1.2	-0.2	-3.2	-1.0	-0.2
Fasting Glucose	1.3	1.6	6.2	1.3	0.3	0.9	0.4	0.9	2.4	1.3	1.6	1.4	-0.2	1.0	1.6	1.1	2.0	1.4	2.5	-1.0	1.1	-0.1	-0.5	0.1	1.1	0.4
Multivitamins +/- minerals	1.3	1.7	5.5	-1.0	-0.4	-0.8	-0.8	-0.9	-2.3	-1.2	-1.2	-1.5	-0.1	-1.2	-2.0	-1.6	-1.4	-1.1	-2.1	0.6	-1.2	-2.0	-1.0	-1.2	-1.0	-0.3
Medication: Simvastatin	1.3	1.9	4.4	1.5	1.5	1.4	0.6	0.1	1.1	1.6	1.2	1.7	-0.2	1.5	1.4	1.8	2.0	1.8	1.6	-0.1	1.5	1.3	0.9	-0.5	2.1	1.7
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	6.1	-0.8	-1.9	-1.6	2.5	1.5	0.3	-1.3	-1.4	-1.2	0.0	-0.9	-1.4	-1.5	-1.2	-1.0	-0.4	1.4	-1.4	-1.6	-2.0	0.6	-2.5	-1.5
Pulse wave reflection index	1.3	1.6	5.5	1.2	1.7	1.5	0.7	-0.5	-0.6	1.6	1.5	1.4	-0.1	1.6	0.9	1.2	1.2	1.4	0.6	-0.4	1.2	1.2	1.1	0.4	2.4	2.1
Blood clot in the leg (DVT)	1.3	1.7	4.5	1.3	2.1	1.9	0.1	0.2	0.5	1.3	2.1	1.3	1.3	1.6	1.1	1.7	1.7	1.1	0.6	0.7	1.6	1.1	1.1	0.4	1.3	1.2
Comparative height size at age 10	1.3	7.1	13.2	3.1	2.3	3.5	1.9	1.6	0.9	3.6	1.9	3.3	2.4	3.2	2.2	3.0	3.2	2.5	3.1	1.2	3.5	2.5	3.0	0.6	3.1	2.6
Supplements: Vitamin C	1.3	1.6	4.0	-1.0	-1.1	-0.4	-0.0	-1.1	-2.0	-0.6	-1.4	-1.4	-0.3	-1.1	-1.7	-1.7	-1.6	-1.4	-1.5	-1.1	-0.9	-1.6	-1.6	-1.3	-1.0	-0.3
Vitamin and mineral supplements	1.2	1.6	5.5	0.9	0.2	0.6	0.4	0.6	2.4	1.0	0.8	1.4	-0.1	0.9	2.0	1.9	1.4	1.2	2.2	-0.5	1.1	2.1	1.0	1.1	0.9	0.1
Chronic bronchitis/emphysema (father)	1.2	1.4	5.1	-1.2	-2.3	-1.4	-1.8	0.0	0.8	-1.0	-0.4	-1.0	-1.3	-1.8	-0.6	-0.7	-0.8	-0.7	0.0	-1.5	-1.2	-0.9	-1.5	-0.2	-1.5	-1.5
Number of incorrect matches in round	1.2	2.0	4.2	-1.9	-1.6	-2.0	0.1	-0.8	-0.4	-2.0	-0.7	-1.5	-2.1	-1.5	-1.0	-0.8	-1.3	-1.3	-1.4	-1.2	-1.8	-1.6	-2.0	0.7	-1.2	-1.5
Had menopause	1.2	1.6	4.2	1.7	0.8	1.5	0.2	-0.1	0.9	1.3	1.7	1.6	-0.2	1.0	0.8	1.4	2.1	1.5	1.6	-0.9	1.4	1.2	0.4	0.2	1.9	1.0
Mouth/teeth dental problems: Dentures	1.2	2.0	4.8	1.2	0.8	1.1	0.8	0.8	1.8	1.2	1.6	1.6	0.3	1.3	1.7	1.8	2.0	1.6	2.2	-0.2	1.4	2.0	1.1	1.5	1.3	0.8
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	6.9	1.0	-0.3	0.2	1.8	1.6	2.6	0.5	0.8	1.1	0.0	0.8	1.2	1.5	1.4	0.8	2.4	0.6	0.8	1.6	0.9	1.3	-0.0	-0.4
Mean time to correctly identify matches	1.2	2.4	6.5	1.9	2.0	1.5	1.2	-0.4	0.6	1.7	1.1	1.9	0.2	2.0	1.2	1.4	2.1	2.0	1.3	0.4	1.6	1.5	1.2	-0.4	2.5	1.9
Heart disease (mother)	1.2	1.4	4.8	1.3	2.2	1.7	-0.5	-0.7	-0.0	1.4	1.7	1.3	0.8	1.2	0.2	1.0	1.3	1.4	-0.0	0.3	1.5	0.7	1.0	-0.3	2.0	1.4
Ever had bowel cancer screening	1.2	1.4	3.1	1.2	0.7	1.0	1.0	1.4	1.5	1.3	1.6	1.2	1.0	1.3	1.1	0.8	1.2	1.2	1.4	1.0	1.1	1.4	0.7	1.8	0.6	0.7
Ulcerative Colitis	1.1	1.6	4.5	1.1	1.5	1.8	-0.8	0.3	-0.3	2.1	0.7	1.6	1.6	1.6	0.2	0.0	0.7	0.7	0.8	0.8	1.9	1.7	1.3	-0.6	1.8	1.3
Ever had hysterectomy (womb removed)	1.1	1.2	4.3	1.0	1.0	0.2	1.3	1.7	1.9	-0.0	0.8	0.9	1.2	1.3	0.9	1.3	1.1	0.6	0.9	2.1	0.7	1.2	0.5	0.9	-0.3	-0.2
Exposure to tobacco smoke outside home	1.1	1.5	6.0	0.9	-0.1	0.8	0.8	1.7	2.5	1.3	0.6	1.3	0.6	0.8	2.3	1.5	1.2	0.9	2.0	0.2	1.3	0.7	1.2	0.4	0.7	0.3
Health satisfaction	1.1	1.5	5.2	-1.2	-1.3	-1.7	0.6	0.6	-0.7	-1.4	-1.2	-0.9	-0.5	-0.7	-1.1	-1.3	-1.1	-1.0	-0.4	0.7	-1.7	-1.3	-2.3	-0.3	-1.9	-1.6
Medication: Omeprazole	1.1	1.3	3.0	-1.2	-1.6	-1.4	-0.9	-0.3	-0.0	-1.1	-0.1	-1.3	-1.7	-1.6	-1.1	-1.0	-0.9	-1.0	-0.4	-1.2	-1.2	-1.0	-0.9	1.0	-1.4	-1.5
Mineral and other dietary supplements	1.1	1.5	5.7	0.7	0.3	0.1	2.0	0.3	2.4	0.4	0.2	1.0	-0.8	0.9	2.0	1.8	1.3	1.5	1.3	-0.6	0.4	2.0	1.2	1.7	0.7	0.6
Financial situation satisfaction	1.1	1.3	7.8	-0.5	-1.3	-1.4	2.8	1.9	1.3	-0.7	-1.7	-0.0	-0.3	0.1	1.1	-0.4	-0.2	-0.1	1.3	0.9	-0.7	-0.4	-1.1	-0.1	-1.6	-1.2
Heart attack/myocardial infarction (self-reported)	1.1	1.4	4.1	-1.5	-1.3	-0.8	-1.0	-1.3	-0.7	-0.5	-1.6	-1.1	-1.1	-1.1	-0.7	-1.7	-1.4	-1.6	-0.9	-2.0	-0.8	-1.4	-1.0	-0.7	-0.7	-1.3
Alcohol drinker status: Previous	1.1	1.3	2.6	-1.1	-1.5	-1.6	0.0	0.3	-0.5	-1.3	-1.3	-1.5	-0.4	-1.6	-1.5	-1.2	-1.6	-1.0	-1.1	0.6	-1.2	-0.2	-0.9	0.6	-1.3	-1.0
Sensitivity / hurt feelings	1.0	1.8	5.2	1.7	2.3	1.3	0.8	0.8	0.1	1.1	0.7	1.1	1.8	1.5	1.1	1.0	1.0	1.5	-0.6	1.9	1.2	0.7	1.8	-1.0	1.1	2.2
Stomach or abdominal pain in last month	1.0	1.2	3.8	-1.2	-1.4	-1.1	-0.2	-1.0	-0.5	-1.0	-0.9	-1.1	-1.3	-1.3	-1.9	-1.0	-0.9	-0.7	-0.3	-0.7	-1.3	-0.8	-2.0	1.1	-0.9	-1.0
Supplements: Glucosamine	1.0	1.3	5.2	-0.6	-0.2	-0.1	-2.1	-0.1	-2.3	-0.5	0.4	-0.9	1.1	-0.8	-1.9	-1.5	-1.1	-1.5	-1.1	0.8	-0.3	-1.7	-1.1	-0.9	-0.8	-0.8
Heart attack	1.0	1.3	3.7	-1.4	-1.0	-0.7	-1.0	-1.3	-0.8	-0.5	-1.4	-1.1	-0.9	-1.0	-0.7	-1.5	-1.3	-1.5	-0.9	-1.9	-0.7	-1.4	-1.0	-0.9	-0.6	-1.2
Medication: Cholesterol lowering	1.0	1.5	3.0	0.8	1.1	1.1	1.3	0.4	1.7	1.5	1.5	1.6	0.4	1.5	1.4	1.4	1.4	1.3	1.5	0.1	1.5	1.0	0.7	-0.2	1.4	1.0
Exposure to tobacco smoke at home	1.0	1.1	5.3	-0.2	-2.2	-1.0	2.3	0.3	1.4	-0.3	-1.2	0.2	-1.5	-0.4	0.5	0.3	0.2	-0.1	2.1	-1.5	-0.3	0.3	-0.6	0.5	-0.2	-1.0
Birth weight	1.0	2.2	8.5	0.0	-1.9	-1.8	1.1	2.5	0.8	-1.4	-0.4	-0.7	0.8	-0.8	-0.4	-1.8	-0.4	-0.9	1.1	1.8	-1.2	-0.9	-1.9	1.2	-2.9	-2.5
Migraine (self-reported)	1.0	1.3	3.6	-0.6	-1.4	-1.4	0.3	0.1	-0.3	-1.6	-1.2	-1.2	-0.7	-1.1	-0.9	-1.9	-1.2	-1.4	-0.5	-0.2	-1.3	-0.9	-1.1	-0.8	-1.5	-1.6
Age started oral contraceptive pill	1.0	1.2	4.3	1.1	0.5	0.5	0.1	-0.0	1.1	0.9	1.8	1.4	-1.2	1.1	0.7	1.0	1.6	1.3	2.1	-1.0	0.7	1.4	0.0	1.1	1.5	0.4
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.9	-1.2	-1.7	-1.4	-0.5	-0.2	-0.2	-1.1	-0.6	-1.3	-1.4	-1.6	-1.0	-1.0	-1.2	-1.1	-0.6	-1.1	-1.1	-1.0	-1.0	0.7	-1.4	-1.3
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.5	1.2	1.8	1.6	0.0	0.4	0.5	1.0	1.9	1.1	1.1	1.3	1.1	1.4	1.5	1.1	0.5	0.7	1.4	0.9	0.9	0.4	1.0	1.0
Schizophrenia vs Biploar Disorder	0.9	1.1	3.2	-1.1	-1.8	-1.3	-0.2	-0.3	0.3	-1.3	-1.7	-1.1	-1.2	-1.5	-0.6	-0.6	-0.7	-0.7	-0.2	-1.0	-1.3	-1.0	-1.3	0.2	-1.3	-1.2
Reaction Time	0.9	1.7	4.5	1.4	2.1	1.4	1.0	-0.6	0.1	1.4	0.3	1.5	0.7	1.8	0.8	1.1	1.3	1.6	0.3	0.7	1.2	1.2	1.1	-0.9	2.1	2.1
Mean Putamen Volume	0.9	1.0	2.7	-0.7	-0.8	-1.5	-0.3	-0.4	-0.8	-1.6	-1.0	-1.1	-1.2	-0.9	-0.6	-1.3	-0.7	-0.8	-0.8	-0.5	-1.3	-1.1	-1.1	0.0	-1.2	-1.3
Lung FEV1/FVC ratio	0.9	4.4	8.8	2.0	2.7	1.9	1.7	2.3	2.0	2.4	2.4	2.1	2.6	2.8	1.6	1.6	1.6	2.0	1.3	3.0	2.2	2.3	2.4	0.4	1.2	2.0
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.9	1.1	0.9	0.9	1.7	1.5	0.8	1.0	1.5	1.2	0.9	1.1	0.3	1.2	1.2	1.5	0.8	1.7	1.1	0.8	-0.0	0.8	0.8	1.1
Length of working week for main job	0.9	1.0	2.7	-0.9	-1.3	-1.6	1.1	0.5	1.0	-1.6	0.3	-0.6	-0.8	-0.7	-0.3	-0.4	-0.6	-0.9	0.2	-0.1	-1.3	-0.4	-1.1	1.2	-1.6	-1.6
Breastfed as a baby	0.9	1.1	7.1	0.9	0.4	0.8	1.8	0.5	1.1	0.7	1.3	0.7	0.4	0.5	0.6	1.2	1.1	1.3	0.3	-0.0	0.8	0.9	0.9	2.7	0.7	1.2
Birth weight of first child	0.9	1.7	7.4	1.7	-0.2	0.4	1.8	2.7	2.0	0.4	0.4	0.8	1.7	0.7	1.4	-0.0	1.1	0.7	1.6	2.0	0.7	0.4	0.4	2.2	-0.8	-0.2
Medication: Allopurinol	0.9	1.2	3.6	1.3	0.1	0.6	1.9	1.2	1.3	1.0	1.4	1.0	0.4	0.6	1.0	1.3	1.6	1.6	1.6	1.0	0.9	1.0	0.3	1.2	0.4	0.8
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.7	-1.5	-1.4	-1.0	-0.0	-0.7	-1.0	-0.8	-1.2	-1.3	-0.5	-1.1	-1.6	-0.9	-1.3	-1.0	-0.9	-0.5	-0.9	-1.5	-1.1	0.6	-1.2	-0.8
Hearing aid user	0.9	1.0	2.0	0.9	1.2	1.3	1.0	-0.2	0.2	1.1	1.0	1.0	0.9	1.3	0.8	0.9	0.8	0.7	0.3	0.3	1.3	1.2	1.3	-1.0	1.4	0.9
Medication: Lisinopril	0.9	1.1	7.2	0.0	1.2	0.8	-2.7	-1.0	-1.2	0.4	0.9	-0.5	1.8	-0.2	-0.1	-0.2	-0.8	-0.8	-1.6	0.3	0.5	-0.1	1.6	-1.5	0.2	0.1
Arm fat-free mass (left)	0.9	4.3	10.7	-2.1	-3.0	-2.1	-1.5	0.1	-1.1	-1.9	-2.5	-2.3	-0.3	-2.5	-1.5	-2.4	-2.7	-3.0	-1.5	-0.7	-1.8	-2.3	-1.6	0.3	-3.3	-2.8
Depression (Nagel 2018)	0.8	1.2	6.5	0.4	-1.5	-0.5	2.5	1.6	1.8	0.1	-0.5	0.5	-0.7	0.1	0.7	0.8	0.8	0.6	2.2	0.2	0.2	0.3	-0.9	1.2	-0.4	-1.0
Body Mass Index (BMI) (2010)	0.8	1.0	3.4	-0.5	-1.1	-1.6	0.5	0.9	0.4	-1.4	-1.1	-1.1	-0.3	-1.0	-0.8	-1.2	-0.9	-0.7	-0.5	1.4	-1.1	-0.6	-1.1	0.5	-1.8	-1.3
Medication: Metformin	0.8	1.2	5.7	1.0	0.1	0.9	-0.1	1.0	1.2	1.7	0.9	1.1	0.4	0.7	1.0	1.0	1.4	1.3	2.4	0.4	1.2	1.1	0.4	-1.1	1.2	0.2
Maternal smoking around birth	0.8	1.2	2.6	-1.4	-1.5	-1.0	-0.5	-0.3	-0.6	-1.1	-1.5	-1.3	-0.2	-1.4	-1.2	-1.0	-1.6	-1.4	-1.2	-0.3	-1.1	-1.2	-0.5	0.0	-1.3	-1.0
Fed-up feelings	0.8	1.4	8.3	0.9	-0.7	-0.2	2.5	2.9	2.5	0.1	0.3	0.6	1.1	0.5	0.9	0.4	0.5	0.7	1.3	1.8	0.0	0.3	-0.0	0.8	-1.3	-0.2
Alcohol usually taken with meals	0.8	1.2	3.1	-1.2	-0.1	-1.1	-1.1	-1.1	-1.6	-1.6	0.5	-0.9	-1.1	-0.7	-1.4	-0.7	-0.7	-1.1	-1.3	-0.5	-1.3	-1.8	-1.7	0.6	-0.7	-1.1
Number of live births	0.8	1.1	3.5	1.3	0.9	0.9	1.4	1.7	0.6	0.7	1.3	0.7	1.6	0.8	0.3	0.7	1.1	1.2	0.2	1.9	0.9	0.4	0.5	1.4	-0.2	1.0
Gout (self-reported)	0.8	1.1	5.3	0.3	-1.5	-0.8	2.3	1.2	1.9	-0.1	0.2	0.3	-1.2	-0.2	0.7	0.4	0.7	0.8	1.8	0.1	-0.2	0.3	-0.6	2.1	-0.3	-0.6
Arm predicted mass (right)	0.8	4.1	11.7	-2.1	-3.2	-2.3	-0.8	0.5	-0.6	-1.9	-2.5	-2.1	-0.4	-2.3	-1.2	-2.3	-2.5	-2.8	-0.7	-0.4	-1.8	-1.9	-1.6	0.6	-3.4	-3.0
Osteoarthritis (self-reported)	0.8	1.0	5.0	-0.3	-1.2	-1.2	1.7	1.1	1.4	-1.0	0.1	-0.2	-1.5	-0.3	-0.2	-0.5	0.2	0.1	0.9	0.4	-1.0	-0.0	-0.8	2.2	-0.8	-1.2
Supplements: Fish oil (including cod liver oil)	0.8	1.1	4.4	-0.5	-1.0	-0.4	-1.4	-0.5	-1.9	-0.3	0.1	-0.8	-0.5	-0.9	-2.1	-2.1	-0.8	-1.2	-0.3	-0.3	-0.6	-1.3	-1.4	-0.3	-0.5	-0.7
Arm predicted mass (left)	0.8	4.1	10.9	-2.0	-3.2	-2.2	-1.2	0.3	-0.8	-1.9	-2.5	-2.2	-0.4	-2.5	-1.4	-2.3	-2.5	-2.9	-1.1	-0.6	-1.8	-2.0	-1.5	0.6	-3.3	-2.9
Irritable Bowel Disease (IBD)	0.7	1.7	6.0	0.9	1.6	2.1	-1.5	-0.6	-0.7	1.9	0.1	1.2	2.5	1.1	0.2	0.1	0.2	0.3	-0.3	0.1	1.9	1.1	1.2	-2.0	1.6	1.7
HbA1C	0.7	0.8	3.9	-0.9	-0.7	-0.5	-1.7	-0.3	0.1	-0.4	-1.4	-0.6	0.1	-0.6	0.2	-0.7	-0.7	-1.3	0.1	-1.1	-0.4	-1.0	-1.0	-2.0	-0.9	-0.7
Diabetes (self-reported)	0.7	1.1	4.2	0.7	0.5	1.0	-0.2	0.4	1.1	1.4	1.3	1.2	0.3	1.0	0.9	1.3	1.4	0.8	2.0	-0.0	1.4	1.4	0.3	-0.8	1.4	0.0
Trunk fat-free mass	0.7	4.2	11.6	-2.1	-3.2	-2.1	-0.9	0.5	-1.0	-1.9	-2.7	-2.3	-0.0	-2.5	-1.5	-2.2	-2.6	-3.0	-1.1	-0.3	-1.7	-2.0	-1.4	0.4	-3.4	-2.9
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	6.5	1.6	2.1	1.8	1.3	1.4	-0.4	1.7	1.7	1.6	2.5	2.2	0.3	0.8	1.4	1.1	0.8	2.4	1.6	1.4	1.5	0.4	0.8	1.6
Qualifications: A levels/AS levels or equivalent	0.7	1.6	4.9	1.6	1.6	0.4	1.9	1.2	0.9	0.2	2.2	1.2	0.0	1.6	1.3	1.2	1.8	1.6	0.9	1.5	0.5	0.5	0.4	1.9	0.4	0.5
Trunk predicted mass	0.7	4.2	11.4	-2.1	-3.1	-2.1	-1.0	0.4	-1.1	-1.8	-2.7	-2.3	0.0	-2.5	-1.5	-2.2	-2.6	-3.0	-1.2	-0.3	-1.7	-2.0	-1.4	0.3	-3.4	-2.9
Peak expiratory flow (PEF)	0.7	1.6	6.5	1.4	1.7	1.2	1.1	1.5	-0.1	1.1	1.4	1.0	2.2	1.4	0.7	0.4	0.9	1.1	0.0	2.5	1.1	0.7	1.3	0.6	0.4	1.6
Arm fat-free mass (right)	0.7	3.4	10.7	-1.9	-2.9	-2.1	-0.8	0.6	-0.5	-1.7	-2.3	-1.9	-0.0	-2.1	-1.1	-2.0	-2.3	-2.6	-0.8	-0.2	-1.6	-1.7	-1.3	0.6	-3.3	-2.8
Whole body fat-free mass	0.7	4.1	12.7	-1.9	-3.1	-2.2	-0.7	0.8	-0.7	-1.9	-2.5	-2.2	0.0	-2.3	-1.4	-2.5	-2.5	-2.9	-1.0	0.1	-1.7	-1.9	-1.5	0.8	-3.6	-3.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	8.7	0.0	0.7	1.3	-1.4	-1.6	-1.1	1.0	-1.0	0.2	0.1	0.1	-0.7	0.8	0.0	0.1	-0.7	-0.9	0.5	-0.5	0.6	-3.0	1.5	1.4
Whole body water mass	0.7	4.2	12.4	-1.9	-3.1	-2.2	-0.9	0.7	-0.8	-1.9	-2.5	-2.2	-0.1	-2.4	-1.5	-2.4	-2.5	-2.9	-1.0	-0.0	-1.7	-2.0	-1.5	0.8	-3.5	-3.0
Medication: Blood pressure	0.7	1.3	4.2	-1.1	-0.5	-0.5	-2.1	-1.9	-1.4	-0.4	-1.0	-1.1	-1.6	-1.4	-1.6	-0.9	-1.1	-0.9	-1.5	-1.4	-0.7	-0.5	-0.2	-1.4	0.5	-0.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.5	-1.3	-1.5	-1.2	0.2	-0.4	0.1	-0.9	0.0	-0.5	-1.6	-0.7	-0.9	-0.6	-0.5	-0.7	0.6	-1.2	-1.2	-0.5	-1.6	-0.4	-0.9	-1.3
Pack years of smoking	0.7	1.0	4.4	-0.4	-2.0	-0.9	1.2	1.1	1.7	-0.4	-0.2	-0.3	-0.8	-0.7	0.5	-0.4	-0.3	-0.3	1.2	-0.9	-0.9	-0.3	-0.5	2.1	-1.5	-1.2
Crohns Disease (2017)	0.6	1.3	6.0	0.6	1.5	1.8	-0.8	-0.4	-0.6	1.3	-0.6	0.9	2.4	0.9	0.3	0.7	0.1	0.1	-0.6	0.2	1.5	0.8	0.9	-2.4	1.2	1.5
Major Depression (MDD)	0.6	0.7	3.1	-0.1	-0.7	-1.1	1.8	1.2	0.7	-1.1	-0.8	-0.2	-0.1	0.0	0.1	-0.9	-0.4	-0.4	0.1	1.2	-0.7	-0.0	-0.1	1.1	-1.4	-0.8
Prostate Cancer	0.6	0.9	1.9	-1.3	-1.2	-1.4	0.3	0.7	-0.2	-1.0	-1.2	-1.0	-0.4	-0.8	-0.5	-0.6	-1.4	-1.1	-0.4	1.1	-0.9	-0.4	-1.2	-0.3	-1.2	-1.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	6.7	0.1	0.0	0.3	-0.4	-1.2	-0.1	0.1	-0.9	0.2	-1.2	0.2	0.1	-0.1	0.5	-0.0	0.6	-1.8	-0.1	-0.4	-0.5	-2.6	0.9	-0.3
Type 2 Diabetes (T2D) (2018)	0.6	1.1	6.5	0.8	-0.1	0.5	0.6	1.1	1.8	1.2	1.2	1.1	0.1	0.7	1.3	0.6	1.1	0.8	2.6	0.1	1.1	1.3	0.4	-0.5	0.7	-0.3
Chronotype (morning person)	0.6	1.4	7.5	-0.3	0.7	0.1	-2.7	-0.8	-1.8	-0.5	-1.7	-1.3	0.7	-1.3	-0.2	-0.4	-1.0	-0.5	-2.7	0.4	-0.4	-1.3	0.7	-1.0	-0.2	0.6
Hearing difficulty/problems: Yes	0.6	0.9	7.2	0.2	-0.7	-0.9	2.7	1.7	1.0	-0.9	-0.3	-0.3	0.1	-0.1	-0.3	-0.2	-0.2	0.3	-0.3	1.9	-0.8	-0.2	-0.1	1.0	-1.4	-0.0
Medication: Atenolol	0.6	0.8	3.7	-1.0	-0.5	-0.4	-0.7	-1.8	-0.7	-0.4	-0.6	-0.5	-1.1	-0.7	-1.2	-0.2	-0.6	-0.8	-0.8	-1.9	-0.7	-0.7	-0.9	-1.0	0.2	-0.3
High blood pressure (mother)	0.6	0.9	3.1	-0.1	-1.1	-0.9	1.2	1.7	1.5	-0.1	0.3	0.2	0.2	-0.2	-0.0	-0.5	0.3	0.3	1.6	1.6	0.1	0.1	-1.1	0.8	-1.1	-1.3
Nervous feelings	0.6	1.2	5.3	-0.1	-1.0	-1.0	2.2	2.3	1.7	-0.5	0.1	-0.1	0.3	-0.2	0.2	0.8	0.1	0.5	0.7	1.9	-0.4	0.2	-0.5	2.2	-1.3	-0.6
Mouth/teeth dental problems	0.6	0.9	3.5	-0.8	0.1	-0.6	-0.5	-0.4	-1.8	-0.7	-0.2	-1.0	0.1	-0.6	-1.1	-1.7	-1.4	-0.7	-1.9	0.7	-0.8	-1.1	-0.9	-0.3	-0.5	0.1
Medication: Ramipril	0.6	0.7	3.1	-0.4	0.6	0.2	-1.0	-1.7	-1.5	-0.2	-0.8	-0.4	-0.5	-0.2	-0.9	-0.3	-0.3	-0.4	-1.0	-1.0	-0.2	-0.9	-1.0	-1.8	0.8	0.3
Emphysema/chronic bronchitis	0.6	0.7	2.8	-0.7	-0.3	0.4	-1.7	-1.5	-0.5	0.2	-1.1	-0.8	0.4	-1.0	-0.9	0.9	-0.5	-0.2	-1.1	-1.2	-0.5	-0.7	-0.3	-0.8	-0.5	0.5
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.5	-0.2	1.0	0.4	0.7	-1.2	-0.1	-0.0	1.6	0.5	-1.1	0.8	0.5	1.1	0.6	0.6	-0.4	-1.3	-0.1	-0.2	0.2	1.5	0.9	1.2
Medication: Aspirin	0.6	0.7	2.9	-1.2	-0.3	-0.4	-1.3	-1.7	-0.9	-0.3	-0.3	-0.3	-1.1	-0.3	-0.9	0.2	-0.4	-0.8	-0.0	-1.6	-0.4	-0.7	-1.6	-0.6	0.1	-0.9
Leg fat-free mass (right)	0.6	3.0	10.4	-1.3	-2.6	-2.0	-0.3	1.3	-0.2	-1.6	-1.9	-1.6	0.2	-1.8	-1.1	-2.5	-2.0	-2.4	-0.5	0.7	-1.4	-1.4	-1.2	1.4	-3.2	-2.7
Loneliness, isolation	0.6	0.8	5.1	0.1	-1.1	-0.7	2.3	1.4	1.9	-0.2	-0.1	0.2	-0.6	-0.1	0.6	0.7	0.4	0.6	1.2	0.4	-0.3	0.2	-0.4	1.2	-0.5	-0.4
Leg predicted mass (right)	0.6	3.2	10.6	-1.4	-2.7	-2.0	-0.4	1.2	-0.3	-1.7	-1.9	-1.7	0.2	-1.9	-1.2	-2.5	-2.1	-2.5	-0.6	0.6	-1.5	-1.4	-1.2	1.4	-3.2	-2.7
Miserableness	0.6	1.0	2.0	-1.2	-0.9	-1.2	0.5	-0.4	-0.5	-1.2	-1.1	-1.1	-1.3	-0.8	-1.3	-0.4	-1.2	-0.8	-1.2	-0.6	-1.4	-0.9	-1.4	-0.4	-1.0	-0.7
Guilty feelings	0.6	0.9	5.3	0.3	-0.2	-0.8	0.6	2.2	0.5	-0.9	-0.4	-0.3	1.5	-0.0	-0.2	-1.0	-0.8	-0.5	-0.3	2.3	-0.5	-0.0	-0.5	-0.3	-1.8	-0.6
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.8	-0.8	-1.6	-1.0	0.0	0.4	0.7	-0.7	-0.7	-0.7	0.1	-0.8	-0.7	-0.6	-0.8	-1.1	0.3	-0.2	-0.6	-0.2	-0.6	0.1	-1.4	-1.7
Medication: Bendroflumethiazide	0.6	0.9	3.6	-0.8	0.4	0.8	-1.7	-1.9	-1.4	0.6	-0.5	-0.2	-0.5	-0.3	-0.7	0.9	-0.3	-0.4	-0.7	-1.6	0.5	0.0	0.6	-1.4	1.7	0.7
Ever smoked	0.6	1.1	6.6	0.4	-1.4	-1.1	2.6	1.6	1.5	-0.3	-0.9	0.2	-1.2	-0.3	0.3	-0.3	0.4	0.8	1.5	1.0	-0.4	0.3	-1.1	1.4	-0.5	-0.7
Basal metabolic rate	0.6	3.4	10.8	-1.7	-2.8	-2.1	-0.6	0.9	-0.5	-1.7	-2.2	-1.9	-0.1	-2.0	-1.3	-2.2	-2.3	-2.6	-0.8	0.1	-1.6	-1.7	-1.3	1.0	-3.3	-2.7
Irritability	0.6	1.0	4.3	-0.3	-1.1	-1.5	2.1	1.8	1.7	-0.9	-0.1	-0.3	-0.6	-0.3	-0.2	-0.0	-0.3	0.1	0.6	1.6	-0.8	-0.2	-0.8	1.2	-1.3	-1.1
Risk taking	0.6	0.8	1.8	-1.4	-0.9	-1.1	-0.0	-0.7	-0.9	-1.2	-0.7	-1.0	-0.6	-0.8	-1.1	-0.9	-1.2	-1.2	-0.8	-0.7	-0.9	-0.7	-1.3	-0.2	-0.8	-0.9
Ever depressed for a whole week	0.6	0.7	3.1	0.0	-0.5	-0.8	1.5	1.5	1.2	-1.0	0.2	0.1	-0.1	0.3	0.2	-0.5	0.0	-0.4	0.4	1.2	-0.4	-0.0	-0.7	1.8	-1.3	-1.1
Cholesterol lowering medication	0.6	0.9	1.7	1.1	1.3	1.0	0.3	0.4	0.4	1.1	0.9	1.2	0.5	1.2	0.5	0.9	1.2	1.1	0.8	0.5	1.1	1.2	-0.1	-0.8	1.2	1.0
Bipolar Disorder (2011)	0.5	0.5	2.3	0.1	1.1	0.7	-1.5	-1.1	0.0	0.5	1.0	0.0	0.4	0.2	-0.4	-0.1	-0.1	-0.2	-0.8	-0.5	0.4	-0.5	0.2	-1.4	0.9	0.8
Crohns Disease (2012)	0.5	0.8	4.5	0.6	0.4	1.7	-0.5	0.2	-0.3	1.5	-0.4	0.9	2.1	0.7	-0.1	0.3	0.2	-0.2	0.4	-0.1	1.7	1.1	0.4	-1.4	0.8	0.7
Blood Red Count	0.5	4.9	18.1	2.5	3.7	3.2	-0.7	0.4	0.2	2.5	4.3	2.2	3.0	2.7	1.1	2.0	1.6	1.5	-0.0	0.4	2.5	1.4	2.6	-1.0	2.0	2.6
Hypothyroidism (self reported)	0.5	1.1	2.5	-1.2	-1.3	-1.2	-0.7	0.0	-1.1	-0.8	-1.6	-1.3	-0.2	-1.5	-0.9	-1.1	-1.3	-1.0	-1.0	0.0	-1.2	-1.1	-0.9	-0.4	-1.5	-0.9
Pack years adult smoking proportion	0.5	0.7	3.3	-0.5	-1.8	-0.8	0.8	0.8	1.2	-0.2	-0.3	-0.5	-0.5	-0.8	0.3	-0.6	-0.6	-0.5	0.9	-0.8	-0.8	-0.3	-0.4	1.5	-1.5	-1.0
Leg fat-free mass (left)	0.5	2.7	9.7	-1.3	-2.5	-1.9	-0.2	1.3	-0.1	-1.6	-1.7	-1.5	0.1	-1.6	-0.9	-2.2	-1.9	-2.3	-0.4	0.7	-1.4	-1.3	-1.1	1.4	-3.1	-2.6
Age when periods started (menarche)	0.5	1.3	3.0	-1.4	-1.1	-1.5	-0.8	-0.1	-0.3	-1.5	-1.3	-1.6	-0.7	-1.4	-1.0	-0.7	-1.4	-0.8	-1.4	0.8	-1.7	-0.9	-1.1	-0.1	-1.5	-0.9
Serious illness, injury or assault to yourself	0.5	0.7	3.0	-0.9	-1.0	-1.0	0.9	-0.6	-0.4	-0.5	-0.3	-0.5	-1.3	-0.5	-0.9	-1.2	-0.5	-0.0	0.0	-0.7	-1.0	-0.7	-1.7	0.7	-0.6	-0.4
Body mass index (BMI)	0.5	2.3	7.1	-1.4	-2.1	-2.2	-0.0	0.6	0.7	-1.8	-1.3	-1.4	-1.1	-1.5	-0.7	-1.9	-1.8	-1.8	-0.8	-0.2	-1.7	-1.1	-1.1	1.4	-2.7	-2.2
Leg predicted mass (left)	0.5	2.6	9.4	-1.3	-2.4	-1.9	-0.2	1.4	-0.1	-1.5	-1.6	-1.5	0.2	-1.5	-0.9	-2.2	-1.9	-2.3	-0.4	0.7	-1.3	-1.2	-1.0	1.4	-3.1	-2.5
Past tobacco smoking	0.5	0.9	5.0	-0.5	1.4	0.9	-2.2	-1.4	-1.9	0.4	0.5	-0.2	1.2	0.4	-0.2	-0.2	-0.7	-0.8	-1.3	-0.5	0.5	-0.0	0.6	-1.1	0.5	0.6
Hearing difficulty/problems with background noise	0.5	0.8	8.6	0.9	-0.0	0.1	2.9	1.1	0.9	0.4	1.0	0.5	-0.3	0.6	0.1	0.2	0.8	1.0	1.0	0.7	0.3	0.5	0.4	1.0	0.4	0.5
Qualifications: None of the above	0.5	1.0	2.2	-1.4	-0.8	-0.8	-1.3	-0.5	-0.9	-1.0	-1.5	-1.2	0.1	-1.1	-0.8	-0.6	-1.4	-1.4	-1.2	-0.2	-0.9	-1.3	-0.4	-0.7	-0.9	-0.9
Hair/balding pattern: Pattern 3	0.5	0.8	4.4	0.3	1.0	0.2	0.2	0.9	0.5	-0.2	2.0	0.2	0.5	0.2	0.5	1.6	0.6	0.8	-0.8	1.2	0.2	-0.0	0.7	2.1	0.1	0.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.1	0.7	-0.4	-0.1	1.4	1.8	0.9	0.2	-0.2	0.4	1.1	0.4	1.0	0.4	0.5	0.4	0.9	1.4	0.5	-0.2	-0.1	0.1	-1.0	-0.5
Loud music exposure frequency	0.5	0.5	4.0	0.7	0.6	-0.1	2.0	1.2	1.1	-0.2	-0.1	0.7	-0.5	0.9	0.8	0.3	0.9	0.8	0.6	0.7	0.2	0.7	0.0	-0.1	0.4	0.2
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.8	-0.5	-1.0	-1.1	-0.2	0.2	-1.3	-1.2	-1.4	-1.1	-0.2	-1.1	-1.0	-1.2	-1.0	-0.7	-0.9	0.3	-1.0	-0.6	-0.5	0.5	-1.3	-0.8
Had major operations	0.5	0.6	4.9	-0.1	0.7	0.8	-0.8	-0.9	-0.7	0.5	-0.3	-0.1	0.6	0.3	-1.1	-0.3	-0.6	-0.2	-1.0	-0.4	-0.1	-0.3	0.8	-2.2	0.5	1.2
Leg pain on walking	0.5	0.6	2.5	0.4	0.9	0.6	-1.1	0.2	0.2	0.6	1.2	0.8	1.6	1.0	0.4	0.8	0.5	0.2	1.0	0.7	0.7	0.7	0.3	-0.8	0.3	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.6	0.3	1.6	0.8	-1.4	-0.7	-0.3	0.3	1.0	0.2	1.3	0.9	0.4	-0.1	-0.1	-0.2	-0.7	-0.0	0.4	0.3	0.7	-1.5	-0.1	0.3
Illnesses of father: Heart disease	0.5	0.7	2.5	1.0	0.3	0.7	1.4	0.5	0.6	0.9	1.2	0.8	-0.1	0.6	-0.3	0.7	1.2	1.2	0.8	0.5	0.6	0.1	0.2	1.6	0.8	0.8
Smoking status: Previous	0.5	0.7	3.5	0.4	-1.0	-1.0	1.9	1.5	1.7	-0.7	0.0	0.0	-0.9	-0.3	0.1	-0.0	0.5	0.7	0.8	1.0	-0.6	-0.2	-0.4	1.1	-0.8	-0.6
Commuting to job workplace: Walk	0.5	0.6	3.8	0.7	0.1	0.0	1.9	1.2	1.1	0.3	-0.3	0.6	-0.2	0.5	0.1	0.1	0.8	1.1	0.8	1.1	0.1	0.4	0.1	0.8	0.3	0.5
Back pain experienced in last month	0.5	0.7	2.6	0.0	0.9	1.1	-0.8	-0.8	-1.3	1.2	-0.3	0.8	-0.1	0.9	-0.8	0.7	0.4	0.2	0.2	-0.6	0.9	0.0	-0.3	-1.6	1.6	1.1
Medication: Gliclazide	0.5	0.6	2.6	-0.9	-0.2	-0.3	-1.2	-1.6	-0.5	-0.2	0.1	-0.5	-1.3	-0.6	-1.1	-0.0	-0.4	-0.1	-0.4	-1.3	-0.7	-0.3	-0.7	-1.3	0.5	-0.2
Illnesses of father: None of the above (group 1)	0.5	0.6	3.4	0.1	0.2	0.3	0.9	1.4	0.6	0.5	-1.0	0.4	1.1	0.6	1.2	0.3	-0.2	-0.2	0.5	1.8	0.7	1.1	1.1	-0.1	0.0	0.2
Average weekly champagne plus white wine intake	0.5	0.6	2.9	-0.9	0.2	-0.6	-0.9	-1.3	-1.5	-0.7	0.0	-0.7	-0.8	-0.5	-1.7	0.2	-0.5	-0.4	-1.1	-0.0	-0.9	-1.0	-0.7	0.4	-0.1	-0.0
Ulcerative Colitis (UC)	0.4	0.8	2.7	0.6	0.9	1.4	-1.5	-0.4	-0.5	1.6	0.8	0.9	1.5	0.8	-0.0	-0.5	0.1	0.2	0.2	0.1	1.2	0.7	0.7	-0.7	1.2	1.0
HDL Cholesterol	0.4	0.7	4.1	-0.8	-0.5	0.2	-1.5	-2.0	-0.9	0.1	-0.7	-0.6	-0.2	-0.5	-0.3	0.1	-0.7	-1.2	-0.6	-2.0	-0.0	-0.2	0.1	-1.0	0.1	-0.7
Systolic blood pressure, automated reading	0.4	1.3	6.4	-0.1	0.7	0.7	-2.0	-2.4	0.1	0.7	0.6	0.4	-1.8	-0.2	-0.3	1.2	0.5	0.7	-0.5	-2.5	0.1	-0.4	0.7	0.7	1.9	1.4
Diabetes (father)	0.4	0.5	2.7	0.9	0.9	0.7	0.3	0.2	0.1	0.2	1.6	0.4	0.9	0.5	1.4	1.1	1.0	0.6	0.2	0.0	1.0	-0.0	0.5	-0.4	0.5	-0.1
Current tobacco smoking	0.4	0.7	2.8	0.8	-0.3	0.6	1.0	0.5	1.0	1.0	-0.6	0.8	0.6	0.5	1.2	0.8	0.8	0.5	1.7	-0.1	1.2	1.2	0.6	-0.4	0.4	-0.2
Taking other prescription medications	0.4	0.6	3.7	0.3	0.6	0.3	1.4	1.3	0.8	0.7	0.3	0.5	1.0	1.0	0.4	0.0	0.1	0.4	0.4	1.9	0.6	0.4	0.6	0.4	-0.2	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.1	0.2	-0.7	-0.4	2.0	0.8	1.3	-0.4	0.5	0.2	-1.1	0.1	0.2	0.9	0.7	0.4	1.0	0.1	-0.3	-0.3	-0.4	1.7	-0.2	-0.6
Falls in the last year	0.4	0.6	2.0	-0.7	-1.4	-0.8	0.6	0.8	0.3	-0.6	-1.1	-0.7	-0.2	-0.8	-0.3	-0.8	-0.7	-0.6	0.3	0.1	-0.5	-0.7	-1.0	0.3	-1.1	-1.1
Pulse rate	0.4	0.8	3.6	0.2	-0.8	-0.7	1.3	1.6	1.9	-0.4	-1.0	0.3	0.2	0.2	1.0	0.0	0.4	0.1	1.3	1.3	-0.1	0.3	-0.1	-0.3	-1.1	-0.9
Happiness	0.4	0.5	2.8	-0.6	-1.0	-0.9	1.7	0.3	1.0	-0.3	-1.0	0.0	-1.3	-0.2	0.4	0.7	0.1	0.4	0.6	-0.7	-0.6	-0.5	-0.9	0.2	-0.4	-0.4
Illnesses of mother	0.4	0.5	1.8	-0.5	-0.3	-0.4	0.1	-0.7	-0.9	-1.0	-1.3	-0.7	-0.6	-0.3	-0.4	-0.0	-0.7	-0.9	-1.3	-0.6	-0.9	-0.9	-0.0	-0.1	-0.5	-0.0
Chronic bronchitis/emphysema (mother)	0.4	0.5	3.2	0.7	-0.5	-0.0	0.6	1.3	0.9	0.3	0.8	0.6	0.6	0.2	0.3	0.1	0.7	0.2	1.8	0.5	0.5	0.8	-0.2	0.7	-0.4	-0.7
High blood pressure (siblings)	0.4	0.6	3.0	-0.4	-0.1	-0.5	-1.3	-0.7	-0.8	-0.5	0.1	-0.7	-0.2	-0.9	-1.7	-0.6	-0.8	-0.5	-1.1	-0.1	-0.5	-0.4	-0.9	-1.7	-0.1	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.6	-0.5	-0.7	-0.6	0.7	-0.3	-0.4	-0.7	-0.2	-0.7	-1.1	-0.9	-0.9	-0.5	-0.5	0.0	-0.9	-0.9	-1.0	-1.3	-1.1	0.2	-0.3	0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.4	0.9	0.9	0.7	0.5	0.3	0.7	0.5	1.0	0.9	0.8	1.2	0.5	0.8	0.8	0.4	0.9	0.3	0.5	0.4	0.5	-0.7	0.5	0.4
Pulse rate, automated reading	0.4	1.4	5.2	-0.1	-2.0	-1.4	1.3	1.6	2.3	-0.6	-0.6	0.1	-0.7	-0.4	0.5	-0.7	0.4	0.3	2.2	1.0	-0.8	0.1	-1.4	1.2	-1.5	-1.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	1.8	1.0	0.7	0.3	-0.3	0.3	0.3	0.5	0.2	0.6	-0.3	0.5	1.1	0.6	0.8	1.0	0.4	0.6	0.5	0.9	1.3	0.1	0.9	0.4
Average weekly red wine intake	0.4	0.6	2.3	-0.5	-0.5	-0.4	-0.9	-1.1	-1.1	-0.7	-0.5	-0.3	-0.9	-0.5	-0.5	-0.3	0.1	-0.7	0.1	-1.5	-0.5	-1.1	-1.4	-1.2	0.1	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.8	0.5	0.0	0.5	0.8	0.9	1.1	0.9	-0.1	0.7	0.6	0.8	1.0	-0.5	0.2	0.4	1.3	0.2	0.6	0.9	0.6	0.2	0.0	0.3
Breast cancer (self-reported)	0.4	0.4	1.8	0.4	-0.0	0.2	1.2	0.6	0.8	0.6	0.4	0.8	0.1	1.0	0.8	0.6	0.7	0.2	1.3	-0.2	0.5	0.3	-0.2	-1.2	0.4	-0.3
Smoking status: Current	0.4	0.6	2.2	0.7	-0.5	0.7	0.8	0.3	0.9	1.0	-0.8	0.7	0.5	0.3	1.0	0.7	0.7	0.4	1.5	-0.3	1.1	1.2	0.6	-0.6	0.5	-0.1
Wears glasses or contact lenses	0.4	0.5	2.1	0.8	0.4	0.9	0.6	1.0	0.3	0.5	0.2	0.3	1.5	0.2	-0.2	1.1	0.5	0.5	-0.4	1.2	0.5	0.2	0.4	-1.0	0.1	0.6
Mother’s age at death	0.4	0.6	3.0	0.2	0.2	0.1	1.6	0.9	1.2	0.2	1.2	0.6	-0.4	0.7	0.3	1.1	0.6	0.5	0.7	0.1	0.1	0.2	-0.0	1.7	-0.0	0.0
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.3	1.0	0.7	1.1	0.8	0.3	-0.0	0.7	0.1	0.9	0.2	0.6	0.8	1.1	1.1	0.9	0.2	-0.1	0.6	-0.3	0.2	0.1	1.1	1.1
Unable to work because of sickness or disability	0.4	0.5	1.9	-0.5	-0.3	-0.8	-0.6	0.4	0.3	-1.1	0.4	-0.9	0.4	-0.6	-0.2	-0.6	-0.7	-0.7	-1.0	0.4	-0.9	-1.0	-0.3	0.4	-1.4	-0.7
Commuting to job workplace: Cycle	0.4	0.5	2.0	0.7	1.3	0.4	-0.1	0.5	0.2	0.0	1.4	0.6	0.7	0.8	0.8	0.6	0.9	0.5	0.5	0.7	0.7	0.8	0.5	0.9	0.4	-0.3
Depressed Affect (Nagel 2018)	0.3	0.6	5.2	0.2	-0.5	-0.4	2.3	1.4	1.5	-0.3	-0.1	0.2	-0.5	0.4	0.5	0.3	0.3	0.5	0.8	0.4	-0.5	-0.0	-0.6	-0.0	-0.6	-0.4
Neuroticism (Nagel 2018)	0.3	0.7	5.6	0.4	-0.1	-0.5	2.4	1.9	1.3	-0.5	0.1	0.0	0.2	0.4	0.0	0.3	0.2	0.4	0.2	1.7	-0.4	-0.1	-0.5	0.4	-0.8	-0.3
Worry (Nagel 2018)	0.3	0.6	3.7	0.1	-0.4	-0.6	1.9	1.4	1.0	-0.6	0.0	-0.3	-0.0	-0.1	-0.5	0.7	-0.0	0.2	-0.1	1.5	-0.6	-0.4	-0.3	1.2	-0.9	-0.2
LDL Cholesterol	0.3	0.4	1.2	0.5	0.7	1.0	-0.8	-0.1	-1.1	0.8	0.1	0.3	0.7	0.3	-0.7	-0.6	0.0	-0.1	-0.7	0.3	0.8	-0.3	0.3	-0.8	0.8	0.8
Blood Eosinophil Count	0.3	2.5	17.0	-0.7	-0.3	-0.0	-1.9	-1.1	-2.4	-0.2	-2.4	-1.4	1.4	-1.2	-1.8	-1.1	-1.9	-1.5	-2.6	0.1	-0.5	-0.7	0.3	-4.1	-0.5	0.1
Blood White Count	0.3	2.3	11.4	-1.6	-0.5	0.1	-2.1	-2.2	-2.0	-0.2	-1.1	-1.4	0.4	-1.5	-1.5	0.4	-1.4	-1.2	-2.1	-1.9	-0.6	-1.8	-1.0	-3.4	-0.0	-0.2
Systolic Blood Pressure	0.3	1.6	6.0	-0.3	1.6	1.2	-2.2	-2.5	-0.3	0.8	-0.0	-0.2	0.0	-0.3	0.1	1.3	-0.1	0.8	-2.1	-1.3	0.3	-0.9	1.4	-1.0	1.6	2.2
Allergy or Eczema	0.3	0.7	3.1	0.8	0.5	0.8	1.8	-0.9	-0.5	0.9	0.5	1.0	-0.4	1.4	-0.3	-0.2	0.8	0.7	0.9	-0.7	0.6	0.7	0.1	0.4	1.5	0.9
Respiratory disease	0.3	0.6	3.0	-0.7	0.0	0.1	-1.0	-0.4	-0.6	-0.1	-1.4	-1.0	0.6	-0.9	-0.8	-0.3	-1.1	-0.5	-1.7	0.3	-0.3	-0.9	0.4	-0.2	-0.7	0.5
Average weekly spirits intake	0.3	0.3	2.8	-0.2	0.1	-0.1	1.7	0.2	-0.3	-0.2	0.2	0.4	-1.2	0.7	-0.3	0.3	0.3	-0.1	0.3	-0.3	-0.3	-0.2	-1.2	-0.0	0.4	0.1
Relative age of first facial hair	0.3	0.7	3.3	0.6	0.9	0.2	1.2	0.9	1.0	-0.0	1.1	0.3	0.7	0.8	0.4	1.2	0.9	0.9	0.2	1.8	0.3	0.1	0.5	1.4	-0.0	0.2
Angina	0.3	0.4	2.2	0.5	-0.3	0.1	1.5	0.7	0.6	0.8	0.4	0.3	-0.2	0.1	0.2	-0.9	0.3	1.0	0.7	0.0	0.1	0.3	-0.9	0.7	-0.1	0.7
Severe depression (siblings)	0.3	0.3	1.0	-0.3	-0.6	-1.0	0.4	0.4	0.6	-0.7	0.6	-0.1	-0.9	-0.2	-0.5	-0.9	-0.1	0.1	0.3	0.0	-0.8	0.4	-0.5	0.6	-0.6	-0.7
Trunk fat percentage	0.3	1.1	3.2	1.1	0.7	0.3	1.7	0.6	1.5	0.5	1.4	1.5	-1.1	1.4	0.7	0.8	1.5	1.1	1.4	-0.2	0.4	0.9	0.3	1.8	0.9	0.4
Townsend deprivation index at recruitment	0.3	0.4	2.7	-0.1	-1.2	-0.1	0.0	0.5	1.2	0.5	-1.7	-0.4	0.2	-0.8	0.4	0.1	-0.4	0.3	0.1	0.0	0.1	0.2	0.6	-0.6	-0.4	0.1
Average weekly fortified wine intake	0.3	0.4	1.5	0.3	-0.2	-0.3	1.2	0.7	0.7	0.0	-0.2	0.6	-0.2	0.6	-0.8	-0.5	0.3	0.2	1.1	0.3	0.1	1.2	-0.7	0.1	0.2	-0.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	4.0	0.3	-0.2	-0.2	0.8	0.4	0.9	-0.3	-0.3	0.3	-0.4	0.2	0.3	0.6	0.6	0.7	0.5	0.2	-0.2	-0.0	0.1	2.0	-0.1	0.3
Qualifications: CSEs or equivalent	0.3	0.3	1.2	0.3	0.7	0.2	0.5	0.8	1.1	0.5	-0.0	0.4	0.7	0.6	0.9	-0.1	0.0	0.7	0.3	0.8	0.1	0.5	0.6	0.2	-0.4	0.9
High blood pressure	0.3	0.9	5.6	-1.1	0.1	-0.1	-2.4	-1.7	-0.7	-0.2	-0.7	-0.9	-0.9	-1.0	-0.9	-0.2	-1.0	-0.7	-1.4	-0.9	-0.4	-0.6	-0.0	-1.5	0.5	0.0
Medication: Levothyroxine sodium	0.3	0.6	1.9	0.4	0.2	-0.3	1.2	1.3	1.1	0.2	0.6	0.7	-0.1	0.8	1.1	0.3	0.9	0.8	1.4	0.8	0.0	0.8	0.2	0.6	-0.3	-0.3
Allergy	0.3	0.6	1.7	0.7	0.9	0.3	-0.1	1.3	1.1	0.3	1.3	0.7	0.5	0.6	1.2	1.0	0.7	0.9	0.5	1.0	0.6	0.9	0.8	0.6	0.3	0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.2	-0.1	0.3	1.0	-0.2	-1.2	-1.0	0.6	-0.2	-0.1	0.6	0.0	-1.1	0.4	-0.3	-0.0	-1.1	-0.5	0.2	0.1	0.3	0.2	0.6	1.5
Neuroticism score	0.3	0.6	3.6	0.6	-0.4	-0.6	1.5	1.9	1.3	-0.4	0.3	-0.1	0.1	-0.1	-0.0	0.3	0.2	0.6	0.1	1.6	-0.6	-0.4	-0.3	0.7	-1.1	-0.1
Worrier / anxious feelings	0.3	0.5	2.7	1.0	0.6	0.5	1.3	1.4	0.4	0.3	0.5	0.4	0.9	0.8	0.1	0.3	0.3	0.4	-0.1	1.7	0.4	0.2	0.7	-0.1	-0.1	0.7
Noisy workplace	0.3	0.4	1.6	0.1	0.8	0.3	0.4	0.9	0.7	0.1	0.3	0.6	1.3	0.9	0.8	0.8	0.3	0.3	0.4	1.0	0.6	0.9	0.4	0.2	-0.2	0.1
Asthma	0.3	0.7	4.7	-0.6	-0.6	-0.3	-0.0	0.7	0.5	-0.2	-2.2	-0.9	0.7	-0.9	-0.1	-0.3	-1.0	-0.4	-1.1	1.2	-0.3	-0.8	0.6	-0.3	-1.3	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.7	0.3	0.3	-0.3	-0.4	-0.0	-1.3	-0.5	0.3	-0.2	0.4	0.2	-0.9	-1.0	-0.4	-1.0	-0.2	0.4	-0.1	-0.6	-0.4	-0.6	-0.2	-0.8
Lung cancer (father)	0.3	0.4	1.4	-0.9	-0.7	-0.7	-0.6	-0.7	-0.0	-0.4	-0.6	-0.3	-0.7	-0.4	0.1	-0.8	-1.0	-0.8	0.0	-1.2	-0.9	0.2	-0.4	-0.5	-0.4	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.2	0.3	1.8	1.1	-0.3	-0.2	-1.4	1.0	0.8	0.6	1.5	1.2	-0.7	0.2	0.2	0.3	-0.3	1.4	0.7	0.7	1.1	-0.4	0.8	1.4
Arm fat mass (right)	0.3	1.0	2.8	-0.8	-1.3	-1.5	0.1	0.3	0.4	-1.3	-0.7	-0.7	-1.2	-0.8	-0.6	-1.3	-0.9	-1.2	-0.4	-0.4	-1.2	-0.9	-0.7	1.5	-1.7	-1.5
Medication: Paracetamol	0.3	0.6	4.4	-0.1	1.0	0.7	-0.7	-0.7	-1.3	0.3	-0.0	0.1	1.2	0.5	-0.6	0.3	-0.2	-0.3	-1.0	0.7	0.3	-0.4	0.1	-2.1	0.4	0.4
Headache pain in last month	0.3	0.5	2.8	-0.1	1.1	0.7	0.5	0.3	-0.2	0.6	0.6	0.5	1.2	1.1	0.3	1.7	0.1	0.2	0.1	1.5	0.5	-0.1	0.3	-0.6	0.2	0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.1	-0.0	-0.4	-0.3	-0.3	0.8	-0.0	-0.3	-0.9	-0.2	1.2	-0.2	0.1	-0.6	-0.4	-0.6	0.0	1.0	0.1	-0.4	-0.4	-1.5	-1.1	-0.9
Number of children fathered	0.3	0.4	2.8	-0.6	-0.8	-0.1	0.2	0.5	-0.0	-0.1	-1.7	-0.7	0.5	-0.8	-0.1	0.1	-0.9	-0.3	-0.7	0.5	-0.2	-0.3	0.3	0.4	-1.0	0.1
Medication for pain relief, constipation, heartburn	0.3	0.5	3.0	0.2	-0.7	-0.6	0.7	1.4	1.3	-0.6	0.3	-0.2	-0.2	-0.6	0.3	-0.6	0.2	0.2	0.3	0.6	-0.4	0.5	0.1	1.7	-0.8	-0.4
Neck or shoulder pain in last month	0.3	0.4	2.2	-0.1	0.5	0.8	-0.2	0.4	-1.0	0.7	-0.4	-0.3	1.5	0.1	-0.2	-0.5	-0.7	-0.3	-1.1	0.6	0.5	-0.6	0.1	-1.1	-0.2	0.6
Medication: Ibuprofen	0.3	0.4	2.2	0.2	-0.1	-0.4	-0.1	-0.3	-1.4	-0.5	0.4	-0.1	-0.0	0.1	-1.5	-1.1	-0.4	-1.1	-0.0	-0.2	-0.2	-0.4	-0.6	-0.7	-0.1	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.4	0.9	0.2	0.4	0.5	0.9	0.5	0.6	0.7	0.6	0.9	0.5	0.6	0.2	0.5	0.7	0.4	0.8	0.2	0.5	0.7	1.2	0.1	0.7
Alcohol intake frequency.	0.3	0.8	4.2	-0.0	0.9	-0.2	-1.2	0.2	-0.9	-0.8	0.8	-0.7	2.0	-0.1	-0.7	-0.5	-0.8	-0.7	-1.7	1.6	-0.2	-0.2	0.0	-0.2	-0.8	-0.2
Number of full sisters	0.3	0.3	2.2	-0.3	-0.8	0.0	0.1	-0.2	0.2	-0.1	-1.4	-0.2	0.3	-0.5	-0.4	-0.3	-0.1	-0.1	0.0	-0.8	-0.2	-0.5	-0.8	-1.5	-0.8	-0.2
Suffer from ‘nerves’	0.3	0.5	1.6	-0.4	-1.2	-0.7	1.3	0.3	0.3	-0.7	-0.6	-0.5	-0.6	-0.6	-0.6	0.4	-0.3	-0.4	-0.1	-0.2	-0.9	-0.9	-0.7	1.2	-0.8	-0.7
Overall health rating	0.3	0.7	3.5	-0.7	-1.1	-0.9	0.6	0.9	0.4	-0.6	-0.4	-0.3	-0.4	-0.4	-0.7	-0.8	-0.7	-0.6	0.4	0.2	-0.8	-1.1	-1.9	-0.1	-1.3	-1.2
Hypertension (Self-reported)	0.3	1.0	6.4	-1.0	-0.1	-0.3	-2.5	-1.6	-0.6	-0.4	-0.7	-1.0	-1.0	-1.2	-0.8	-0.5	-1.0	-0.8	-1.3	-0.9	-0.6	-0.6	-0.1	-1.4	0.3	-0.3
Illnesses of siblings: Diabetes	0.3	0.4	1.7	0.4	-0.5	-0.5	0.6	1.3	0.6	-0.1	0.3	0.2	0.6	0.1	0.5	-0.9	0.3	0.0	1.0	0.7	0.2	0.1	-0.7	-0.3	-0.6	-1.3
Friendships satisfaction	0.3	0.3	1.4	-0.3	-0.5	-0.6	0.0	-0.4	0.2	-0.7	-0.6	-0.3	-0.7	-0.4	-0.3	-0.5	-0.1	-0.1	-0.3	-0.8	-0.8	-0.8	-1.2	-0.6	-0.8	-0.2
Eye problems/disorders: Cataract	0.3	0.4	2.2	-0.8	-0.4	-0.3	-1.5	-0.6	-0.1	0.0	0.9	-0.3	-0.3	-0.4	-0.7	0.6	-0.3	-0.4	0.5	-0.7	-0.5	-0.4	-1.1	-0.2	-0.3	-0.8
Asthma (self-reported)	0.3	0.6	4.4	-0.7	-0.5	-0.2	-0.2	0.5	0.2	-0.0	-2.1	-0.9	0.7	-0.9	-0.2	-0.4	-1.1	-0.3	-1.3	1.0	-0.3	-0.8	0.5	-0.5	-1.1	0.3
Medication: Aspirin	0.3	0.4	2.1	-0.7	0.0	-0.2	-0.8	-1.2	-0.6	-0.2	0.3	0.1	-1.1	0.0	-0.5	0.5	0.2	-0.4	0.3	-1.1	-0.1	-0.4	-1.4	0.2	0.5	-0.7
Commuting to job workplace: Public transport	0.3	0.4	0.9	0.5	0.6	0.4	-0.3	-0.2	-0.2	0.6	0.8	0.7	-0.1	0.6	0.6	0.9	0.8	0.6	0.7	-0.7	0.7	0.6	-0.4	-0.6	1.0	-0.0
Average weekly beer plus cider intake	0.3	0.5	1.7	0.6	-0.1	0.8	0.2	0.8	1.0	1.1	-0.3	0.5	1.3	0.4	0.9	0.0	0.3	0.4	0.7	0.5	1.0	0.8	1.0	0.9	-0.2	0.2
Diastolic blood pressure, automated reading	0.3	1.0	5.8	-0.7	-0.2	-0.3	-1.6	-2.2	-0.0	-0.3	-0.4	-0.4	-2.0	-0.9	-0.5	0.5	-0.3	0.1	-0.9	-2.4	-1.0	-0.8	-0.2	1.1	0.4	0.5
Heart disease (siblings)	0.3	0.4	2.1	0.2	-0.3	0.6	-0.7	0.4	-0.1	0.7	-0.5	0.2	1.5	-0.1	-0.6	0.4	0.1	-0.1	0.3	0.4	0.8	0.7	0.2	-1.4	0.1	-0.2
Bipolar Disorder (2018)	0.2	0.4	1.7	-0.0	1.1	0.5	-1.0	-1.0	-0.6	0.2	1.3	0.3	-0.1	0.3	-0.3	0.6	0.2	-0.0	-0.5	-0.6	0.4	0.3	0.1	-0.3	1.0	0.2
Bipolar Disorder or Schizophrenia	0.2	0.4	2.4	-0.3	0.3	0.5	-1.0	-1.4	-0.5	0.3	0.8	0.3	-0.3	0.3	-0.4	0.3	0.1	-0.4	0.2	-1.6	0.4	0.7	-0.1	-0.1	1.0	-0.2
Alzheimer’s Disease (in mother)	0.2	0.3	1.3	-0.2	0.6	0.5	-1.1	-1.0	-0.5	0.4	0.9	0.2	0.3	0.3	0.0	-0.3	-0.2	-0.2	0.0	-0.9	0.0	-0.1	0.2	-0.7	0.3	0.4
Alzheimer’s Disease (in father)	0.2	0.2	1.3	0.1	0.7	0.2	-0.5	0.3	-0.2	-0.0	1.1	-0.0	1.1	0.2	-0.3	-0.5	0.1	0.2	-0.4	0.4	-0.1	-0.1	-0.3	-0.1	-0.7	-0.0
Alzheimer’s Disease (including proxy)	0.2	0.3	2.8	0.1	1.1	0.5	-0.9	-0.2	-0.2	0.6	1.7	0.3	0.9	0.6	-0.1	-0.4	0.0	0.2	-0.1	-0.0	0.1	0.1	-0.0	-0.7	-0.2	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.6	2.0	-0.7	-0.6	-1.0	1.1	-0.3	0.0	-1.0	-1.4	-0.9	-0.8	-0.9	-0.5	-0.6	-0.8	-0.4	-1.1	-0.0	-0.9	-0.6	-0.1	-0.3	-0.7	-0.1
Breast Cancer	0.2	0.4	1.1	-0.1	-0.7	-0.7	0.2	0.9	-0.5	-0.7	-0.6	-0.9	0.5	-1.0	-0.5	-0.8	-0.5	-0.0	-0.6	1.1	-0.2	-0.5	-0.3	0.7	-0.7	-0.3
Age at First Birth	0.2	0.2	1.9	0.3	-0.2	0.6	0.3	1.0	0.2	0.5	-0.6	-0.0	1.4	-0.2	0.4	0.4	0.2	0.2	0.3	0.8	0.4	-0.0	0.1	-0.1	-0.3	0.2
Lupus	0.2	0.3	0.9	0.5	0.3	0.4	0.6	-0.4	-0.5	0.2	-0.9	0.0	-0.1	0.1	0.6	-0.6	0.2	0.5	-0.6	-0.6	-0.3	-0.8	0.4	-0.9	0.1	0.9
Neuroticism (2016)	0.2	0.2	1.4	-0.3	-0.2	-0.4	0.1	-0.1	0.1	-0.4	0.2	-0.0	-0.3	0.1	-0.6	-0.2	-0.2	-0.6	0.1	-0.6	-0.3	-0.1	-1.2	-1.1	-0.3	-0.6
Primary Biliary Cirrhosis	0.2	0.3	1.2	-0.3	0.1	-0.2	0.7	0.6	0.5	-0.5	0.8	-0.1	0.3	0.2	0.1	0.9	0.0	-0.2	0.0	0.9	-0.5	-0.2	-0.4	1.1	-0.7	-0.5
Schizophrenia (2014)	0.2	0.4	1.5	-0.0	-0.0	0.4	-0.1	-0.7	0.3	0.5	0.2	0.7	-0.4	0.5	0.4	0.8	0.6	0.1	1.2	-1.2	0.6	1.2	0.0	0.5	1.0	-0.4
Triglycerides	0.2	0.4	2.4	0.1	0.6	-0.0	0.6	1.0	0.5	0.2	1.5	0.6	-0.3	0.7	-0.1	-0.5	0.2	0.5	0.4	0.6	0.0	0.5	-0.4	1.2	0.3	0.5
Blood Platelet Count	0.2	2.3	16.4	-1.3	-0.5	-0.1	-2.2	-2.6	-0.1	0.1	-0.1	0.1	-1.0	0.1	-0.8	0.1	-0.8	-1.6	0.8	-3.7	-0.5	-0.6	-0.9	-4.0	0.5	-1.3
BMI	0.2	1.4	4.9	-1.2	-1.0	-1.9	0.4	1.1	0.8	-1.5	0.0	-0.9	-0.7	-0.6	-0.6	-1.3	-1.6	-1.5	-0.8	0.9	-1.4	-0.7	-0.5	1.6	-2.2	-1.7
Height	0.2	4.7	16.4	2.5	0.8	2.2	2.3	1.0	0.6	2.6	1.6	3.1	0.2	2.7	1.8	1.9	3.0	1.7	4.0	-0.5	2.5	2.7	1.1	1.9	2.5	1.2
Smoking Status	0.2	0.6	3.0	-0.2	-1.7	-0.7	1.4	0.5	0.2	-0.5	-1.7	-0.5	-0.1	-0.9	-0.3	-0.0	-0.1	-0.2	0.6	0.1	-0.3	-0.4	-0.9	-0.5	-0.9	-1.1
Neuroticism	0.2	0.6	2.5	0.2	-0.6	-0.8	1.6	1.5	1.4	-0.8	0.3	-0.3	-0.4	-0.2	-0.1	0.3	-0.0	0.1	0.3	0.8	-1.0	-0.3	-0.5	0.4	-1.2	-0.6
Hand grip strength (left)	0.2	0.5	3.2	-0.5	-1.0	-0.2	0.5	-0.2	-0.6	-0.4	-1.8	-0.7	0.1	-0.7	-0.6	-0.9	-0.7	-0.8	-0.5	-0.1	-0.3	-0.5	-0.3	-0.4	-1.0	-0.6
Number of treatments/medications taken	0.2	0.4	3.3	0.2	1.0	0.7	-0.4	-0.5	-0.7	0.7	0.3	0.3	0.5	0.6	-0.3	0.2	0.1	0.2	-0.3	0.3	0.4	-0.3	0.0	-1.8	0.5	0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.5	0.8	-0.7	0.1	-0.3	0.2	0.3	0.4	-0.1	0.2	-0.9	-0.4	-0.6	-0.1	0.8	0.9	1.2	-0.3	0.1	0.4	-0.4	0.3	0.4	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.1	-0.3	-1.1	-0.3	-0.3	-0.4	0.1	0.0	0.1	-0.4	-0.6	-0.7	-0.7	-0.5	0.0	-0.1	0.7	-0.8	-0.5	0.0	-0.7	0.2	-0.3	-0.3
Medication for hormone replacement therapy	0.2	0.3	1.4	0.5	-0.7	-0.2	0.0	0.9	0.9	0.1	-0.7	0.2	0.0	-0.4	-0.0	0.3	0.6	0.6	1.2	0.6	-0.1	0.2	-0.2	0.2	-0.4	0.1
Supplements: Zinc	0.2	0.3	2.0	0.0	0.3	0.2	-0.5	-0.3	-0.8	-0.0	-0.1	-0.2	0.8	-0.0	-1.4	-0.3	-0.2	-0.2	-0.6	0.3	-0.0	-0.3	-0.3	-1.1	-0.2	0.3
Hand grip strength (right)	0.2	0.5	2.3	-0.5	-0.8	-0.4	-0.0	-0.0	-0.7	-0.5	-1.5	-0.9	0.1	-0.7	-0.6	-1.4	-0.9	-0.8	-0.7	0.4	-0.6	-0.7	-0.2	-0.4	-1.2	-0.6
Waist circumference	0.2	0.8	3.5	0.7	0.0	0.1	1.9	1.7	1.7	0.5	0.0	0.8	0.0	0.8	1.2	0.4	0.7	0.7	0.9	0.9	0.4	0.6	0.4	1.6	-0.3	0.2
Forced vital capacity (FVC)	0.2	0.9	2.0	0.9	1.2	1.2	1.1	0.5	-0.8	1.0	1.0	1.1	1.4	1.4	-0.1	0.8	1.1	0.8	0.8	1.4	0.9	0.7	0.6	0.7	0.6	1.0
Pain all over the body in last month	0.2	0.2	0.6	-0.3	-0.6	-0.7	0.7	0.5	0.5	-0.6	-0.2	-0.5	-0.1	-0.6	0.1	-0.2	-0.4	-0.1	-0.2	0.8	-0.7	-0.8	-0.0	0.5	-0.8	-0.1
Fluid intelligence score	0.2	0.4	1.3	-0.5	-0.1	-0.2	0.9	-1.1	-0.7	-0.2	-1.1	-0.5	-0.7	-0.5	-0.3	0.0	-0.6	-0.3	-1.0	-0.8	-0.3	-0.2	0.4	-0.7	0.5	0.5
Weight	0.2	0.9	3.7	-0.6	-1.5	-1.2	0.5	1.1	0.6	-0.9	-0.8	-0.5	-0.3	-0.6	-0.4	-1.0	-0.8	-1.2	0.2	0.2	-0.8	-0.6	-0.7	1.6	-1.9	-1.6
Hip circumference	0.2	0.9	3.1	-1.0	-1.8	-1.2	0.3	0.4	0.8	-0.8	-1.2	-0.5	-1.2	-0.8	-0.4	-0.5	-0.7	-1.1	0.3	-0.9	-1.0	-0.5	-0.8	1.1	-1.4	-1.6
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.1	-0.1	0.6	0.5	0.7	-0.3	-0.1	-0.3	0.4	0.4	0.2	0.5	-0.8	1.0	0.5	-0.0	-0.3	0.1	-0.0	-0.5	-1.0	1.0	0.0	0.4
Depression (self-reported)	0.2	0.2	0.7	-0.4	-0.5	-0.5	0.3	-0.2	-0.2	-0.5	-0.8	-0.5	-0.4	-0.4	-0.5	-0.8	-0.6	-0.6	-0.5	-0.2	-0.7	-0.5	-0.2	0.1	-0.5	-0.5
Standing height	0.2	2.2	5.1	1.8	1.1	2.0	1.3	1.2	0.1	1.9	1.0	1.9	1.4	1.9	0.9	1.8	2.2	1.2	2.3	0.8	1.9	1.2	0.7	0.6	1.4	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.4	0.2	-0.7	-0.1	0.8	1.2	0.5	-0.4	-0.2	-0.4	0.6	-0.4	-0.9	-0.5	-0.0	-0.3	-0.2	0.6	-0.3	-1.1	-0.7	0.5	-1.0	-0.4
Hair/balding pattern: Pattern 4	0.2	0.4	3.5	0.0	0.7	0.5	-1.1	-0.9	-0.8	0.5	-0.1	0.1	-0.4	0.3	-0.1	-0.0	-0.0	-0.4	0.3	-0.3	0.3	0.0	0.3	-1.9	0.8	-0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.8	0.8	0.9	0.2	0.3	-0.1	-0.3	-0.3	1.4	0.1	0.1	0.3	0.3	0.7	0.7	0.7	-0.5	0.5	-0.0	-0.1	0.2	0.8	-0.1	0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	2.2	-0.1	-0.8	-1.0	0.7	1.5	0.5	-0.5	-0.1	-0.3	0.1	-0.4	0.1	-0.6	-0.0	-0.0	0.5	0.9	-0.7	-0.4	-0.4	0.8	-1.4	-1.0
Medication: Amlodipine	0.2	0.3	1.4	0.5	-0.2	0.3	1.2	0.7	0.8	0.3	-0.5	0.3	0.0	0.2	0.2	0.1	0.6	0.7	0.5	0.4	0.2	0.6	-0.1	-0.8	0.2	0.6
Body fat percentage	0.2	0.7	3.5	0.6	0.3	-0.1	1.4	0.5	1.4	0.2	1.0	0.9	-1.2	0.9	0.5	0.6	0.9	0.8	0.8	-0.4	-0.0	0.5	0.3	1.9	0.4	0.3
Comparative body size at age 10	0.2	0.6	1.5	-0.6	0.0	-1.0	-1.0	-0.7	-0.5	-1.2	-0.1	-0.9	-0.4	-0.7	-0.1	-0.5	-0.8	-0.9	-1.1	-0.2	-0.7	-1.0	-0.1	-0.9	-0.7	-1.1
Wheeze or whistling in the chest in last year	0.2	0.4	1.7	-0.4	-1.2	-0.3	0.7	0.0	1.3	-0.2	-1.1	-0.2	-0.8	-0.6	0.4	0.6	-0.0	-0.1	0.5	-0.9	-0.2	0.1	-0.0	0.9	-0.4	-0.5
Qualifications: College or University degree	0.2	0.6	3.4	0.3	-0.1	-0.4	1.5	0.1	0.2	-0.3	1.4	0.6	-1.5	0.3	-0.2	0.0	0.8	0.4	0.9	-0.1	-0.1	0.1	-0.9	1.8	0.4	-0.6
Angina (self-reported)	0.2	0.3	1.8	0.4	-0.2	0.1	1.3	0.6	0.5	0.6	0.5	0.3	-0.0	0.2	0.1	-0.9	0.2	0.8	0.5	0.1	0.0	0.0	-1.0	0.5	-0.2	0.6
Leg fat mass (right)	0.2	0.6	2.5	-0.4	-1.1	-1.1	0.7	0.9	1.2	-0.6	-0.4	-0.2	-0.8	-0.3	0.2	-0.6	-0.5	-0.6	0.3	-0.2	-0.8	-0.3	-0.1	1.6	-1.4	-1.0
Family relationship satisfaction	0.2	0.2	1.1	-0.4	-0.0	-0.1	-0.5	-0.5	-0.5	-0.0	-0.8	-0.2	-0.4	-0.2	-0.4	-0.2	-0.2	-0.1	-0.4	-0.6	-0.4	-0.5	-0.6	-1.0	-0.1	0.0
Long-standing illness, disability or infirmity	0.2	0.3	1.0	0.4	0.5	0.6	0.7	0.7	0.7	0.6	-0.1	0.5	0.9	0.5	0.5	0.7	0.3	0.5	0.2	1.0	0.7	0.6	0.5	-0.1	0.2	0.5
Medication for cholesterol	0.2	0.2	1.6	-0.1	0.3	0.1	0.5	0.9	0.1	-0.1	0.6	-0.0	1.3	0.4	0.6	0.1	-0.3	-0.4	-0.0	0.9	0.2	-0.3	0.1	0.5	-0.6	-0.4
Arm fat mass (left)	0.2	0.9	2.6	-0.7	-1.3	-1.4	0.4	0.6	0.8	-1.1	-0.4	-0.5	-1.2	-0.5	-0.4	-1.0	-0.7	-1.0	-0.0	-0.3	-1.1	-0.6	-0.6	1.6	-1.6	-1.5
Number of self-reported non-cancer illnesses	0.2	0.3	1.5	-0.0	0.8	0.7	0.6	0.1	0.8	0.4	0.7	0.4	0.2	0.6	0.1	0.9	0.4	0.5	-0.4	0.6	0.5	0.2	-0.1	1.2	0.5	1.0
High cholesterol (Self-reported)	0.2	0.4	2.3	0.1	0.6	0.2	1.5	0.1	0.7	0.4	0.4	0.7	-0.6	0.8	0.0	0.7	0.6	0.6	0.3	0.1	0.6	0.5	-0.5	-0.0	0.9	0.3
Medication: Paracetamol	0.2	0.3	2.6	-0.2	0.8	0.4	-0.6	-0.8	-0.9	0.2	0.6	0.3	0.3	0.5	-0.5	0.6	0.1	-0.1	-0.3	0.0	0.1	-0.5	-0.2	-1.6	0.5	0.1
Medication: Atorvastatin	0.2	0.3	2.1	-0.9	-0.2	-0.0	-0.1	-0.9	0.1	0.4	0.4	0.1	-0.4	-0.0	0.2	-0.4	-0.5	-0.3	0.1	-1.4	0.1	0.0	-0.9	-0.6	0.2	-0.2
Fractured/broken bones in last 5 years	0.2	0.3	1.5	-0.1	0.4	-0.6	0.5	-0.5	-0.5	-0.8	0.0	-0.1	-1.2	0.1	-0.6	-0.3	-0.1	0.1	-0.7	-0.0	-0.9	-0.8	-0.8	-0.4	0.1	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.5	0.7	-0.3	-0.3	1.6	1.5	0.3	-0.3	0.5	0.5	0.7	0.6	0.5	0.0	0.5	0.2	0.9	1.0	-0.0	0.2	-0.1	1.1	-0.8	-0.4
Pain experienced in last month	0.2	0.4	1.0	1.0	0.1	0.1	0.0	0.3	0.8	0.2	0.1	0.5	-0.5	0.2	1.0	0.0	0.7	0.7	1.0	0.1	0.5	1.0	0.9	0.9	0.6	0.3
Leg fat mass (left)	0.2	0.8	2.9	-0.7	-1.4	-1.3	0.5	0.8	1.0	-0.8	-0.6	-0.5	-0.8	-0.6	-0.2	-0.9	-0.8	-0.8	0.0	-0.2	-1.0	-0.5	-0.4	1.6	-1.7	-1.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.5	0.5	0.1	0.1	1.2	-1.0	-0.5	-0.2	0.4	0.1	-1.0	0.1	-0.4	0.3	0.8	0.3	-0.1	-0.9	-0.1	-0.4	-0.4	-0.1	0.6	0.2
Schizophrenia (2018)	0.1	0.3	2.6	-0.4	-0.4	0.2	-0.6	-1.0	-0.2	0.2	-0.0	0.2	-0.3	0.0	-0.2	0.0	-0.1	-0.5	0.7	-1.6	0.1	0.7	-0.1	0.2	0.5	-0.5
Ovarian Cancer	0.1	0.2	1.1	0.1	-0.4	-0.7	-0.2	0.4	0.0	-0.8	0.1	-0.1	-0.8	-0.3	-0.5	0.4	0.2	-0.2	0.2	0.1	0.0	-0.1	-0.3	0.6	-0.1	-1.1
Rheumatoid Arthritis	0.1	0.1	0.6	0.3	-0.0	-0.3	-0.7	0.4	0.8	-0.6	-0.3	0.1	-0.3	-0.3	0.1	0.3	0.6	0.2	0.4	0.1	-0.1	0.2	0.1	0.5	0.1	-0.3
Heel T-Score	0.1	0.6	4.7	0.8	0.7	-0.1	1.6	1.2	0.6	-0.0	0.7	0.2	0.7	0.6	-0.2	-0.2	0.1	0.7	0.3	2.2	-0.2	0.9	0.6	0.6	-0.2	0.8
Cardiovascular Disease	0.1	0.3	1.5	0.0	1.2	0.4	0.2	-0.2	0.6	0.3	0.4	0.3	-0.3	0.4	0.2	0.9	0.3	0.8	-0.6	0.4	0.2	0.2	0.4	-0.7	1.0	1.1
Lung FVC	0.1	0.4	3.1	-0.6	-0.5	-0.2	1.4	-0.7	-0.9	-0.1	-0.5	0.1	-0.7	0.2	-1.8	-0.0	-0.1	-0.3	0.1	0.0	-0.3	-0.2	-0.4	1.2	0.5	0.0
Tanning	0.1	1.0	4.9	-0.9	-0.1	0.1	-1.6	-0.4	-1.4	0.0	-0.8	-1.1	0.9	-1.0	-0.9	-1.1	-1.8	-0.9	-2.2	0.8	-0.2	-0.6	0.5	-0.3	-0.6	0.5
Medication: Co-codamol	0.1	0.2	0.6	-0.4	0.3	-0.2	-0.4	-0.1	-0.7	-0.3	0.4	-0.1	0.4	0.2	-0.2	-0.7	-0.4	-0.6	-0.0	0.3	0.1	-0.1	-0.6	-0.4	-0.2	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.9	0.1	-0.5	-0.2	-0.4	-0.1	-0.4	0.2	-0.5	-0.5	0.1	-0.7	-0.5	-1.0	-0.5	0.2	-0.2	0.4	-0.4	0.2	0.2	-0.7	-0.3	0.4
Hayfever, allergic rhinitis or eczema	0.1	0.3	2.3	0.1	-0.2	0.2	1.5	-0.9	-0.9	0.3	-0.5	0.3	-0.4	0.6	-0.9	-0.6	0.0	-0.1	0.3	-0.6	0.1	0.0	-0.3	-0.2	0.7	0.3
Sitting height	0.1	0.6	2.8	-0.1	-1.4	-0.2	0.0	0.4	-0.4	-0.1	-0.7	0.2	-0.1	-0.1	-0.6	-0.8	0.1	-1.1	1.7	-1.1	-0.2	-0.4	-1.4	-0.0	-0.8	-1.6
Trunk fat mass	0.1	0.5	3.5	0.4	-0.4	-0.4	1.3	0.8	1.3	-0.1	0.5	0.7	-1.0	0.6	0.3	0.1	0.6	0.2	1.1	-0.3	-0.2	0.3	-0.1	1.9	-0.3	-0.6
Hair/balding pattern: Pattern 2	0.1	0.2	0.7	-0.2	-0.4	0.0	0.1	-0.6	-0.0	-0.1	-0.8	-0.3	-0.3	-0.4	-0.7	-0.2	-0.3	-0.2	-0.5	-0.8	-0.0	0.0	-0.1	-0.5	0.1	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.2	0.5	-0.2	0.1	0.5	0.5	-0.3	0.8	-0.6	0.0	0.9	-0.1	-0.2	-0.9	-0.1	0.7	0.4	1.1	0.0	0.5	0.3	-1.1	-0.0	0.9
Illnesses of siblings	0.1	0.1	1.2	-0.2	0.1	-0.0	0.9	-0.0	-0.0	-0.3	-0.1	-0.1	-0.4	0.3	0.7	0.0	-0.0	-0.2	-0.1	0.1	-0.4	-0.2	0.4	1.1	-0.3	0.1
Arm fat percentage (right)	0.1	0.4	3.1	0.1	-0.1	-0.6	0.9	0.3	0.9	-0.5	0.6	0.3	-1.2	0.3	0.1	-0.3	0.2	0.1	0.2	-0.3	-0.4	0.1	0.0	1.8	-0.3	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.5	4.7	-0.5	0.8	0.4	-0.7	-1.0	-2.2	0.3	0.0	-0.0	0.3	0.4	-1.4	-0.1	-0.3	-0.4	-0.4	0.5	-0.1	0.1	0.1	-0.3	0.4	0.5
Leg fat percentage (right)	0.1	0.2	1.0	-0.1	-0.3	-0.4	0.6	0.0	1.0	-0.1	0.2	0.2	-1.0	0.1	0.3	0.1	-0.0	0.1	0.1	-0.6	-0.5	-0.1	0.3	0.9	-0.3	0.1
Worry too long after embarrassment	0.1	0.2	1.1	1.0	0.7	0.1	-0.6	0.7	-0.3	-0.3	0.7	0.3	0.3	0.4	-0.2	-0.3	0.6	0.2	-0.1	0.6	0.1	-0.3	-0.1	-0.2	0.1	0.0
Medication: Blood pressure	0.1	0.1	1.0	0.1	0.3	0.5	-0.6	-0.3	0.6	0.3	-0.1	0.0	0.6	0.1	0.3	0.2	0.0	-0.2	-0.1	0.2	0.3	-0.1	0.3	-1.0	0.2	0.0
Whole body fat mass	0.1	0.5	3.5	-0.1	-0.7	-0.8	1.1	0.7	1.1	-0.5	0.1	0.2	-1.0	0.1	0.0	-0.2	0.0	-0.3	0.5	-0.2	-0.6	-0.2	-0.3	1.9	-0.9	-0.8
Chest pain or discomfort	0.1	0.2	0.8	-0.3	-0.3	-0.2	0.2	0.1	0.0	0.2	0.6	-0.6	0.2	-0.5	-0.4	-0.8	-0.7	0.0	-0.4	0.3	-0.3	0.1	-0.1	0.9	-0.4	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.4	-0.2	0.0	-0.2	0.6	0.3	0.5	-0.0	-0.6	-0.0	-0.5	0.1	0.3	0.1	-0.3	0.1	-0.2	-0.2	-0.2	-0.1	0.2	0.1	-0.2	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.9	0.5	0.3	0.9	0.5	-0.1	-0.4	0.8	-0.2	0.3	0.4	0.3	-0.1	0.4	0.6	0.4	0.1	0.3	0.8	0.1	0.6	-0.2	0.6	0.8
Arm fat percentage (left)	0.1	0.5	4.2	0.3	-0.1	-0.6	1.2	0.7	1.2	-0.4	0.7	0.5	-1.2	0.6	0.2	-0.1	0.4	0.2	0.6	-0.0	-0.4	0.3	0.0	2.0	-0.3	-0.4
Mood swings	0.1	0.2	1.5	0.1	0.6	-0.1	1.2	0.7	-0.0	-0.2	1.0	0.2	-0.2	0.6	-0.3	-0.0	-0.2	-0.1	-0.2	0.8	-0.2	-0.5	-0.6	0.2	-0.0	-0.2
Qualifications: nursing, teaching	0.1	0.2	1.1	0.5	0.2	-0.1	-0.4	0.0	-0.4	-0.3	0.8	-0.1	-0.2	-0.2	-0.9	-0.8	0.1	0.1	-0.2	0.4	-0.3	-0.4	-0.1	1.0	-0.3	-0.0
Leg fat percentage (left)	0.1	0.3	1.3	-0.4	-0.7	-0.8	0.4	-0.0	0.8	-0.4	-0.1	-0.2	-1.1	-0.4	-0.2	-0.3	-0.3	-0.1	-0.2	-0.8	-0.8	-0.4	-0.2	1.1	-0.7	-0.2
Hair Pigment	0.0	1.1	3.8	-0.5	-0.3	0.2	-1.6	-1.2	-0.8	-0.7	-0.5	-0.9	1.7	-1.1	-1.1	0.0	-1.1	-1.0	-1.9	-0.9	-0.5	-1.0	-0.1	-1.9	-0.9	0.7

Hub : Genes

POLR2J4

Models

Trait associations