Best TWAS P=7.4e-08 · Best GWAS P=6.81e-08 conditioned to 0.091
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | STEAP2 | 0.30 | 0.08 | lasso | 4 | 0.15 | 4.1e-05 | -3.9 | 5.3 | 1.4e-07 | -0.84 | 0.02 | 0.91 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | GTPBP10 | 0.08 | 0.01 | blup | 61 | 0.03 | 7.8e-03 | -5.4 | 5.4 | 7.4e-08 | -0.83 | 0.00 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | GTPBP10 | 0.08 | 0.10 | lasso | 4 | 0.10 | 1.0e-09 | -4.6 | 5.3 | 1.3e-07 | -0.86 | 0.01 | 0.98 | FALSE |