Hub : Genes

GTPBP10

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1380	0.0470	2.1e-06	0.062	0.039	0.063	0.090	0.098	4.9e-08	1.6e-05	3.9e-08	4.7e-11	6.6e-12
2	GTEx	Artery Tibial	0.1802	0.0528	8.4e-07	0.021	NA	0.108	NA	0.097	8.3e-03	NA	9.0e-09	NA	5.3e-08
3	GTEx	Brain Frontal Cortex BA9	0.1548	0.0613	3.6e-03	0.147	NA	0.052	NA	0.104	1.0e-04	NA	1.7e-02	NA	1.1e-03
4	GTEx	Breast Mammary Tissue	0.1300	0.0540	1.4e-03	0.038	NA	0.033	NA	0.041	4.6e-03	NA	8.4e-03	NA	3.6e-03
5	GTEx	Breast Mammary Tissue (Female)	0.0934	0.0619	6.3e-02	0.113	NA	-0.002	NA	0.060	3.0e-04	NA	3.8e-01	NA	7.1e-03
6	GTEx	Cells Transformed fibroblasts	0.1320	0.0460	1.2e-05	0.132	NA	0.104	NA	0.113	4.0e-10	NA	3.5e-08	NA	7.8e-09
7	GTEx	Heart Left Ventricle	0.2046	0.0703	8.8e-05	0.043	NA	0.188	NA	0.153	2.5e-03	NA	2.8e-10	NA	1.6e-08
8	GTEx	Muscle Skeletal	0.0689	0.0232	3.7e-05	0.035	NA	0.028	NA	0.039	2.2e-04	NA	8.8e-04	NA	9.4e-05
9	GTEx	Nerve Tibial	0.0936	0.0432	4.4e-03	0.017	NA	0.034	NA	0.035	2.1e-02	NA	1.8e-03	NA	1.5e-03
10	GTEx	Pituitary	0.2160	0.0810	3.1e-03	0.012	NA	0.012	NA	0.006	1.6e-01	NA	1.6e-01	NA	2.2e-01
11	GTEx	Prostate	0.2030	0.0830	2.8e-03	-0.004	NA	0.000	NA	0.004	4.2e-01	NA	3.1e-01	NA	2.4e-01
12	GTEx	Skin Sun Exposed Lower leg	0.0700	0.0310	7.0e-03	0.023	NA	0.020	NA	0.009	5.0e-03	NA	8.4e-03	NA	5.0e-02
13	GTEx	Testis	0.2220	0.0680	1.5e-05	0.148	NA	0.139	NA	0.157	4.3e-07	NA	9.8e-07	NA	1.9e-07
14	GTEx	Thyroid	0.0660	0.0300	4.0e-03	0.020	NA	0.012	NA	0.010	9.9e-03	NA	4.0e-02	NA	5.5e-02
15	NTR	Blood	0.0119	0.0054	2.3e-03	0.017	0.006	0.009	0.005	0.013	2.1e-06	4.9e-03	3.5e-04	5.3e-03	3.8e-05
16	ROSMAP	Brain Pre-frontal Cortex	0.0688	0.0214	1.3e-07	0.072	0.059	0.071	0.062	0.067	1.3e-09	4.0e-08	1.9e-09	1.9e-08	5.8e-09
17	TCGA	Bladder Urothelial Carcinoma	0.0440	0.0250	4.9e-03	0.019	0.031	0.014	NA	0.025	8.4e-03	1.1e-03	2.2e-02	NA	2.9e-03
18	TCGA	Breast Invasive Carcinoma	0.0498	0.0239	1.3e-07	0.043	0.031	0.035	NA	0.035	2.9e-09	4.1e-07	9.2e-08	NA	7.9e-08
19	TCGA	Cervical Squamous Cell Carcinoma	0.0830	0.0400	5.0e-04	0.011	0.035	0.027	NA	0.006	8.9e-02	7.8e-03	1.6e-02	NA	1.5e-01
20	TCGA	Glioblastoma Multiforme	0.1740	0.0860	3.2e-03	0.032	0.089	0.077	NA	0.065	3.7e-02	1.2e-03	2.4e-03	NA	4.9e-03
21	TCGA	Kidney Renal Clear Cell Carcinoma	0.0534	0.0290	2.9e-04	0.020	0.033	0.015	NA	0.020	2.3e-03	1.1e-04	6.8e-03	NA	2.1e-03
22	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1400	0.0630	2.4e-05	0.091	0.095	0.082	NA	0.086	7.2e-06	4.4e-06	2.0e-05	NA	1.3e-05
23	TCGA	Brain Lower Grade Glioma	0.0499	0.0277	2.5e-04	0.040	0.019	0.011	NA	0.021	1.9e-05	2.6e-03	1.7e-02	NA	1.5e-03
24	TCGA	Prostate Adenocarcinoma	0.0347	0.0170	5.8e-04	0.034	0.014	0.011	NA	0.018	1.7e-04	1.2e-02	2.4e-02	NA	5.2e-03
25	TCGA	Soft Tissue Sarcoma	0.0610	0.0330	3.1e-03	0.051	0.037	0.045	NA	0.033	5.5e-04	2.8e-03	1.1e-03	NA	4.7e-03
26	TCGA	Thyroid Carcinoma	0.0810	0.0320	4.9e-08	0.096	0.079	0.093	NA	0.097	1.3e-09	4.0e-08	2.3e-09	NA	1.0e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Fasting Glucose	7.2	8.6	18.9	0.6	1.5	4.3	3.7	3.5	3.3	0.9	3.9	0.8	2.4	3.1	-0.3	3.5	1.0	1.3	3.1	2.6	3.4	3.6	3.4	2.9	3.2	3.6	3.4	3.5	3.4
Diastolic blood pressure, automated reading	6.7	20.9	41.1	-4.6	-5.4	-5.7	-5.6	-4.2	-4.3	-2.7	-5.2	-4.3	-6.4	-5.6	-3.1	-4.1	-3.8	-5.0	-5.0	-2.4	-4.6	-4.7	-3.6	-3.4	-3.6	-4.7	-4.7	-5.3	-4.4
Risk taking	4.3	6.3	15.4	-1.1	-2.0	-3.0	-3.3	-3.4	-2.5	-1.6	-3.9	-1.8	-2.6	-1.6	-2.0	-1.8	-1.6	-0.4	-1.8	-2.8	-3.1	-1.8	-3.4	-2.5	-3.4	-2.7	-2.8	-2.6	-2.3
Impedance of arm (right)	4.2	19.8	37.0	0.3	1.5	4.7	5.1	4.8	5.4	4.7	4.3	2.1	3.0	3.6	1.2	4.5	1.6	1.5	6.0	5.7	5.2	6.0	4.2	5.9	3.9	5.4	5.5	4.7	6.1
Diabetes (father)	3.9	4.8	7.8	2.8	2.0	2.1	2.4	2.4	2.5	0.8	1.9	1.5	2.5	2.2	1.7	2.6	0.6	2.7	2.3	1.1	2.5	2.6	2.3	1.4	2.2	2.6	2.6	2.5	2.4
Alzheimer’s Disease (in father)	3.7	4.0	5.7	1.3	1.4	2.3	2.4	2.3	2.2	1.6	2.2	1.8	2.1	2.0	1.2	1.9	1.0	1.4	2.1	1.9	2.4	2.2	2.0	2.0	2.1	2.2	2.4	2.3	2.2
Impedance of arm (left)	3.7	17.3	33.1	0.5	1.8	4.3	4.8	4.5	5.2	4.4	4.0	2.1	3.1	3.6	1.1	4.2	1.6	2.0	5.6	4.9	4.9	5.8	3.7	5.0	3.8	5.1	5.2	4.2	5.6
Prospective memory result	3.5	4.3	9.8	-1.6	-2.6	-2.5	-2.7	-2.5	-2.0	-1.5	-3.1	-1.9	-2.4	-1.8	-0.2	-1.2	-2.0	-1.2	-1.4	-1.8	-2.4	-1.1	-2.5	-1.7	-2.9	-2.2	-2.1	-2.2	-1.7
Medication: Cholesterol lowering	3.4	5.2	7.9	1.1	1.1	2.4	2.3	2.4	2.8	2.1	2.0	2.0	2.1	2.4	1.3	2.1	2.3	1.2	2.7	2.6	2.6	2.4	2.3	2.7	2.4	2.8	2.6	2.5	2.6
Impedance of whole body	3.1	15.9	29.0	1.1	2.3	4.1	4.7	4.4	5.0	3.5	4.0	2.3	3.2	3.6	1.2	4.1	1.5	2.3	5.0	4.5	4.7	5.4	3.7	4.5	3.9	4.9	5.0	4.2	5.3
Osteoporosis (self-reported)	3.0	3.8	8.2	-1.6	-2.1	-2.3	-2.5	-2.4	-1.7	-0.3	-2.9	-1.6	-2.8	-1.8	-1.4	-1.2	-2.5	-1.2	-1.8	-1.5	-2.2	-1.0	-2.2	-1.7	-2.2	-1.8	-2.0	-2.3	-1.4
Reaction Time	2.8	5.3	10.4	-1.6	-2.9	-2.7	-2.6	-3.0	-2.5	-1.8	-2.8	-2.1	-2.4	-2.7	-0.3	-1.9	-2.5	-1.8	-1.2	-1.4	-2.8	-1.2	-2.9	-1.6	-3.2	-2.6	-2.5	-2.5	-1.9
Arm predicted mass (right)	2.6	13.5	28.3	-1.7	-2.0	-4.0	-4.3	-3.9	-4.3	-3.9	-3.3	-1.9	-3.2	-3.7	-1.2	-4.1	-1.0	-2.8	-4.7	-3.4	-4.3	-5.3	-3.1	-4.0	-2.9	-4.5	-4.6	-4.1	-4.7
Basal cell carcinoma (self-reported)	2.6	3.1	7.3	1.2	1.4	1.9	1.9	1.6	1.8	1.6	1.4	1.8	2.2	2.1	1.3	1.2	2.7	1.5	2.3	1.4	1.8	1.3	1.3	1.3	2.0	1.7	1.8	2.0	2.1
Number of incorrect matches in round	2.5	4.1	7.5	-1.4	-2.5	-1.9	-2.1	-2.5	-2.4	-2.2	-2.3	-2.5	-1.7	-1.4	-1.0	-1.2	-2.4	-1.2	-1.1	-2.2	-2.4	-0.3	-2.7	-2.0	-2.7	-2.3	-2.1	-2.1	-1.7
Lung FEV1/FVC ratio	2.4	12.4	36.1	3.7	5.0	2.9	3.8	2.6	3.1	2.6	2.5	4.4	5.2	5.4	1.9	3.6	4.1	6.0	3.9	-0.5	3.2	3.4	1.2	0.5	2.6	3.4	3.5	3.4	2.5
Townsend deprivation index at recruitment	2.4	3.3	6.4	-1.1	-1.5	-2.5	-2.3	-1.9	-1.5	-1.5	-2.4	-1.3	-2.1	-1.8	-0.2	-1.9	-1.5	-0.7	-1.8	-1.9	-2.0	-1.8	-1.8	-1.9	-1.9	-1.8	-1.9	-2.4	-2.1
Arm fat-free mass (right)	2.4	12.3	26.1	-1.7	-2.0	-3.8	-4.1	-3.7	-4.1	-3.7	-3.1	-1.9	-3.1	-3.5	-1.3	-4.0	-1.0	-2.8	-4.4	-3.2	-4.1	-5.1	-2.9	-3.7	-2.8	-4.4	-4.4	-3.9	-4.4
Depression (Nagel 2018)	2.3	3.5	10.5	-1.9	-2.9	-1.2	-1.8	-1.6	-1.9	-1.3	-1.4	-2.7	-2.4	-2.1	-2.5	-0.7	-3.2	-2.6	-1.6	-1.2	-1.8	-0.7	-1.2	-0.6	-1.8	-1.8	-1.8	-1.7	-1.2
Medication for cholesterol	2.3	3.5	6.7	2.0	2.6	1.8	2.5	1.6	1.9	1.3	2.0	1.9	2.6	2.4	1.8	1.1	2.4	2.1	2.2	0.8	1.8	1.5	1.0	0.7	1.9	2.0	2.0	1.7	1.5
Other serious medical condition/disability diagnosed by doctor	2.1	2.7	6.1	-1.1	-1.1	-2.5	-2.1	-1.9	-1.1	-0.6	-2.5	-0.9	-2.3	-1.2	-0.3	-2.1	-1.4	-0.6	-1.3	-1.1	-1.7	-1.8	-1.8	-1.6	-1.8	-1.7	-1.6	-2.1	-1.5
Headache pain in last month	2.1	3.6	6.7	0.4	1.9	2.0	2.3	2.2	1.7	1.7	2.1	2.3	2.2	2.4	0.3	2.6	2.2	1.5	1.6	0.9	2.1	1.4	1.7	1.5	1.8	1.9	2.1	2.4	1.9
Arm fat-free mass (left)	2.1	10.7	22.1	-1.2	-1.8	-3.6	-3.9	-3.6	-3.9	-3.5	-3.0	-1.8	-2.9	-3.2	-0.9	-3.6	-1.1	-2.4	-4.1	-3.1	-3.9	-4.7	-2.8	-3.4	-2.8	-4.1	-4.1	-3.6	-4.1
Prostate Cancer	2.0	2.8	7.6	-0.9	-0.3	-1.9	-1.7	-1.9	-1.8	-0.9	-1.9	-0.8	-1.0	-1.0	-0.2	-1.9	0.3	-0.5	-1.9	-2.0	-2.1	-2.8	-2.1	-2.7	-1.3	-1.9	-1.9	-1.8	-2.1
Diabetes (mother)	2.0	2.5	4.9	0.9	0.6	1.8	1.7	1.8	1.9	0.6	1.9	1.0	1.3	1.3	0.8	2.2	0.2	1.3	1.4	1.4	1.8	2.2	1.8	1.2	2.0	2.0	1.8	1.8	2.0
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	7.4	-0.4	-1.0	-2.2	-1.9	-1.8	-2.0	-1.4	-1.6	-1.5	-2.1	-2.3	-1.2	-1.7	-1.5	-1.0	-2.7	-1.9	-2.0	-2.0	-1.6	-1.9	-1.7	-2.0	-2.0	-2.1	-2.3
Arm predicted mass (left)	2.0	10.0	21.4	-1.4	-1.9	-3.6	-3.8	-3.3	-3.7	-3.2	-2.9	-1.9	-3.0	-3.3	-0.8	-3.5	-1.1	-2.7	-4.0	-2.6	-3.7	-4.6	-2.4	-3.0	-2.6	-3.9	-4.0	-3.5	-3.9
Smoking Status	1.9	4.6	9.3	-1.3	-1.2	-1.8	-2.6	-2.7	-2.7	-1.2	-3.0	-0.3	-1.9	-0.6	-2.8	-1.2	0.9	-0.4	-2.0	-2.9	-2.5	-2.6	-3.0	-2.9	-2.0	-2.5	-2.5	-1.6	-2.3
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	7.0	0.2	0.2	1.4	1.5	1.2	1.3	1.5	1.5	1.0	0.8	0.6	1.6	1.4	1.3	-0.6	2.4	2.2	1.4	2.1	1.4	2.6	0.9	1.5	1.5	1.6	2.0
Age at last live birth	1.9	2.8	8.2	2.1	2.9	1.6	1.9	1.3	1.4	2.0	1.7	2.4	2.2	1.5	1.5	1.2	2.7	1.5	1.6	0.8	1.3	0.7	1.1	0.5	1.7	1.4	1.4	1.7	1.4
Qualifications: A levels/AS levels or equivalent	1.8	4.0	7.2	-0.1	1.6	1.8	2.4	2.5	2.5	1.2	2.6	1.9	1.2	1.2	0.7	2.3	0.6	0.6	1.8	2.5	2.4	1.6	2.5	2.4	2.7	2.4	2.4	2.1	2.5
Supplements: Calcium	1.8	2.0	5.1	-1.4	-1.7	-1.4	-1.5	-1.7	-1.5	-0.0	-1.3	-1.4	-1.6	-2.1	0.5	-1.2	0.0	-2.2	-0.6	-0.3	-1.7	-1.4	-1.3	-0.7	-1.6	-1.6	-1.6	-1.6	-1.2
Type 2 Diabetes (T2D) (2018)	1.7	3.2	7.2	0.6	0.9	2.4	1.9	1.6	1.8	1.6	2.0	1.0	1.7	1.7	1.0	1.6	0.9	0.2	2.3	2.2	1.7	2.6	2.0	2.4	1.4	1.8	1.8	2.3	2.7
Financial difficulties in last 2 years	1.7	2.3	5.7	-1.0	-2.0	-1.8	-1.9	-1.9	-1.4	-0.6	-2.4	-1.6	-2.2	-1.2	-1.7	-0.8	-2.0	-0.9	-0.7	-1.3	-1.7	-0.4	-1.8	-1.2	-1.8	-1.4	-1.4	-1.3	-1.0
Mean time to correctly identify matches	1.7	3.3	7.0	-0.6	-2.0	-2.1	-2.2	-2.5	-2.0	-1.3	-2.5	-1.7	-1.8	-1.9	0.4	-1.8	-2.2	-0.9	-0.8	-1.0	-2.3	-0.8	-2.5	-1.4	-2.6	-2.0	-2.0	-2.0	-1.3
Number of full sisters	1.7	2.1	5.7	-0.6	-1.4	-1.8	-1.9	-1.7	-1.7	-1.1	-2.4	-0.9	-2.1	-1.4	-0.0	-1.0	-1.4	-0.6	-1.2	-1.2	-1.6	-1.0	-1.8	-1.3	-1.9	-1.5	-1.4	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	9.3	-0.6	0.8	2.4	2.3	1.9	2.0	1.7	2.1	0.7	2.7	3.0	-1.0	2.5	1.3	1.9	2.5	0.3	2.1	1.9	1.3	0.9	1.7	2.0	2.0	1.7	1.8
Multivitamins +/- minerals	1.6	2.0	5.5	-1.2	-0.6	-0.7	-1.4	-1.6	-2.1	-2.3	-0.8	0.0	-0.9	-0.8	-1.1	-0.7	-0.8	-1.4	-1.9	-1.3	-1.8	-2.0	-1.5	-1.5	-1.1	-1.9	-1.9	-1.1	-1.7
Chronic bronchitis/emphysema (father)	1.6	1.9	7.7	-1.4	-2.3	-0.9	-1.0	-1.1	-0.8	-0.6	-0.8	-2.8	-1.8	-2.0	-0.4	-0.5	-2.8	-2.5	-0.0	0.5	-1.1	0.4	-0.4	0.7	-1.7	-0.9	-1.0	-1.1	-0.2
Trunk fat-free mass	1.6	9.0	19.4	-1.8	-2.0	-3.1	-3.5	-3.1	-3.6	-3.6	-2.5	-2.0	-2.7	-3.1	-1.0	-3.1	-1.2	-2.7	-3.7	-2.6	-3.5	-4.4	-2.2	-2.9	-2.5	-3.8	-3.8	-3.1	-3.6
Trunk predicted mass	1.6	9.2	19.5	-1.8	-2.1	-3.1	-3.5	-3.1	-3.6	-3.6	-2.5	-2.1	-2.7	-3.2	-1.1	-3.1	-1.3	-2.8	-3.8	-2.6	-3.5	-4.4	-2.2	-2.9	-2.5	-3.8	-3.8	-3.2	-3.6
Age at first live birth	1.6	2.8	9.0	0.1	1.4	2.4	2.1	1.5	1.3	3.0	2.2	0.9	2.1	1.8	-0.6	2.0	2.4	0.8	1.6	0.8	1.5	1.7	1.1	0.6	1.9	1.5	1.5	1.7	1.6
Suffer from ‘nerves’	1.6	2.5	5.5	-2.2	-1.9	-0.9	-1.5	-1.5	-1.9	-1.0	-1.1	-1.3	-2.0	-1.6	-2.1	-0.9	-0.1	-2.3	-1.8	-0.9	-1.8	-1.5	-1.5	-1.1	-1.2	-1.7	-1.9	-1.7	-1.7
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	4.1	0.1	1.3	2.0	1.6	1.8	1.0	0.9	2.0	1.7	1.5	0.8	0.7	1.4	1.7	-0.1	0.9	1.8	1.5	0.6	1.6	1.3	2.0	1.2	1.3	1.7	1.3
HDL Cholesterol	1.5	2.5	5.9	-0.1	-0.3	-0.9	-1.6	-1.7	-2.0	-1.3	-0.9	-1.6	-1.0	-1.7	-0.2	-2.4	-1.1	-1.0	-2.0	-2.0	-1.9	-1.9	-1.3	-1.7	-1.2	-1.9	-2.2	-1.8	-2.4
Birth weight of first child	1.5	2.8	9.8	1.6	3.0	1.8	1.7	0.4	1.0	1.0	1.0	3.1	2.5	2.5	2.2	0.9	2.3	2.1	2.1	0.6	0.8	0.7	-0.1	0.3	0.6	1.2	1.2	1.6	1.4
Medication: Ventolin 100micrograms inhaler	1.5	1.9	4.6	0.7	0.4	0.5	1.1	1.9	2.0	1.5	1.2	0.1	0.5	0.6	1.2	1.1	-0.2	0.5	1.1	2.1	1.7	1.6	2.1	1.3	2.2	1.6	1.7	1.2	1.7
Migraine (self-reported)	1.5	1.9	6.6	0.2	0.6	1.4	1.5	1.3	1.5	2.6	1.2	0.7	1.4	1.7	-0.2	1.6	2.1	1.5	1.4	0.5	1.5	1.7	0.9	0.9	1.1	1.4	1.5	1.4	1.5
Whole body fat-free mass	1.5	8.4	18.1	-1.8	-2.1	-3.1	-3.4	-3.1	-3.4	-3.1	-2.5	-1.7	-2.7	-3.0	-1.1	-3.0	-0.8	-2.7	-3.5	-2.5	-3.4	-4.3	-2.3	-2.8	-2.4	-3.6	-3.7	-3.1	-3.5
Whole body water mass	1.5	8.6	18.6	-1.8	-2.1	-3.2	-3.5	-3.1	-3.5	-3.1	-2.6	-1.7	-2.7	-3.0	-1.1	-3.0	-0.8	-2.7	-3.5	-2.5	-3.4	-4.3	-2.4	-2.8	-2.4	-3.7	-3.7	-3.2	-3.6
Mother’s age at death	1.5	1.8	4.2	-0.2	-1.4	-1.6	-1.7	-1.3	-1.6	-0.0	-1.7	-1.7	-1.9	-2.1	-0.3	-1.2	-0.5	-1.0	-1.9	-1.0	-1.4	-0.9	-1.1	-0.9	-1.6	-1.5	-1.3	-1.4	-1.3
LDL Cholesterol	1.4	2.3	4.7	-0.6	-1.1	-1.3	-1.7	-1.8	-1.8	-1.1	-1.5	-1.2	-0.9	-1.0	-1.5	-1.6	-0.6	-0.5	-1.8	-1.9	-1.8	-1.1	-1.5	-1.9	-0.9	-1.9	-1.9	-1.9	-2.2
Illnesses of mother	1.4	1.7	5.9	-0.7	-0.1	1.8	1.2	1.2	1.1	1.1	1.7	-0.1	-0.0	-0.2	0.5	0.8	-0.0	-1.9	1.3	2.4	1.0	1.5	1.7	2.4	1.2	1.2	1.0	1.3	1.6
Ever taken oral contraceptive pill	1.4	1.5	3.3	1.5	1.4	0.8	0.9	1.3	1.2	0.9	0.7	0.9	1.1	1.5	1.0	1.6	1.7	1.8	0.4	0.3	1.3	1.2	1.4	0.4	1.5	1.4	1.3	1.5	1.2
Medication: Lisinopril	1.4	1.8	5.4	0.0	1.2	1.4	1.3	1.6	1.7	0.6	1.6	1.2	0.5	1.0	1.1	1.2	-0.1	-0.2	1.0	1.8	1.5	0.9	2.3	1.5	1.9	1.3	1.4	1.5	1.8
Alcohol drinker status: Previous	1.4	1.6	3.2	-0.3	-0.1	-1.3	-1.2	-1.5	-1.5	-1.7	-1.0	-0.3	-0.6	-0.6	0.3	-1.8	-0.9	-0.6	-1.3	-1.8	-1.5	-1.3	-1.3	-1.4	-1.6	-1.5	-1.5	-1.4	-1.5
Lung cancer (father)	1.3	1.6	3.3	0.5	-1.3	-1.6	-1.6	-1.3	-1.3	-0.4	-1.7	-1.3	-1.0	-1.1	-0.9	-1.8	-0.2	-0.2	-1.3	-1.1	-1.2	-1.0	-1.3	-1.0	-1.7	-1.2	-1.3	-1.6	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	3.9	0.1	0.7	2.0	1.6	1.1	0.7	0.1	1.7	0.7	1.3	1.4	-0.3	1.3	0.6	-0.5	1.7	1.6	1.2	1.2	1.2	1.6	1.0	0.9	1.2	1.9	1.9
Handedness (chirality/laterality): Left-handed	1.3	1.5	4.2	0.0	0.2	-0.8	-1.1	-1.5	-1.7	-1.2	-1.1	-0.5	-0.7	-1.0	0.4	-1.4	-0.5	-0.2	-1.3	-1.6	-1.6	-1.4	-1.5	-2.0	-1.3	-1.6	-1.6	-1.3	-1.6
Number of operations (self-reported)	1.3	2.0	5.1	-1.1	-1.9	-1.5	-1.5	-2.0	-1.5	0.1	-1.7	-1.5	-1.3	-1.5	-0.0	-1.4	-0.6	-1.7	-0.5	-0.1	-1.8	-1.0	-1.6	-0.4	-2.3	-1.7	-1.6	-1.6	-0.8
Age at First Birth	1.2	1.7	5.2	1.1	1.7	2.2	1.9	0.9	0.5	0.8	1.7	1.2	2.0	1.8	-0.3	0.5	2.3	0.5	1.7	0.8	1.1	0.7	0.5	0.4	1.3	0.7	1.0	1.5	1.2
Frequency of depressed mood in last 2 weeks	1.2	1.6	6.0	-2.1	-2.5	-0.8	-1.2	-0.7	-0.9	-0.7	-0.8	-2.0	-2.2	-1.2	-2.1	-0.1	-1.6	-2.1	-1.2	-0.3	-0.8	-0.1	-0.4	0.2	-0.8	-0.9	-0.9	-1.0	-0.5
Impedance of leg (left)	1.2	6.0	12.8	1.2	1.9	2.3	3.0	2.7	3.0	1.2	2.4	1.3	2.2	2.6	0.8	2.7	0.6	2.1	2.9	2.2	2.9	3.6	2.2	2.3	2.4	3.1	3.2	2.7	3.2
Father’s age at death	1.2	1.6	3.3	-0.8	-1.1	-1.2	-1.5	-1.8	-1.2	-1.4	-1.4	-1.1	-1.7	-1.3	-0.5	-1.0	-1.4	-0.9	-0.9	-0.8	-1.8	-1.1	-1.4	-1.4	-1.4	-1.4	-1.5	-1.4	-1.1
Gout (self-reported)	1.2	1.6	5.2	-0.1	0.2	0.7	1.0	1.5	1.6	1.3	0.9	1.3	0.8	1.7	-0.5	1.3	2.3	0.6	1.3	1.1	1.5	0.5	1.4	1.1	2.1	1.5	1.4	1.4	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	5.2	0.3	0.5	1.2	1.3	0.4	1.2	1.4	0.9	1.1	0.8	1.2	0.7	1.0	1.0	-0.2	2.3	1.7	0.9	1.4	0.3	1.9	0.4	1.1	1.2	1.2	1.8
Financial situation satisfaction	1.2	1.4	5.6	-1.3	-2.4	-0.9	-1.2	-1.1	-1.4	-1.1	-1.0	-1.1	-1.7	-1.4	-1.9	0.1	-1.4	-1.5	-1.1	-0.6	-1.0	-0.2	-0.9	-0.2	-1.3	-1.2	-1.1	-0.7	-0.7
Basal metabolic rate	1.2	6.8	14.4	-1.7	-2.0	-2.8	-3.1	-2.8	-3.0	-2.7	-2.3	-1.5	-2.5	-2.8	-1.0	-2.8	-0.7	-2.5	-3.1	-2.0	-3.0	-3.8	-2.0	-2.3	-2.2	-3.2	-3.3	-2.8	-3.1
Bipolar Disorder or Schizophrenia	1.1	2.8	11.2	-0.8	-1.4	-1.3	-1.6	-1.9	-1.6	-0.8	-1.7	-1.7	-2.1	-2.0	-0.8	-1.9	-3.4	-1.7	-1.7	-0.7	-1.9	-0.8	-1.6	-0.9	-2.1	-1.6	-1.7	-1.8	-1.4
Schizophrenia (2014)	1.1	2.4	5.4	-0.8	-1.1	-1.3	-1.7	-1.8	-1.4	-0.6	-1.8	-1.4	-2.0	-1.5	-0.9	-2.0	-2.3	-1.1	-1.5	-1.1	-1.9	-1.1	-1.5	-1.4	-1.6	-1.5	-1.7	-1.9	-1.6
Triglycerides	1.1	1.8	4.7	-0.7	-0.9	1.1	1.2	1.7	1.6	1.4	1.5	-0.7	0.5	0.3	-1.1	1.4	0.3	0.1	0.9	1.7	1.6	2.2	2.0	2.1	1.3	1.4	1.5	1.0	1.5
Relative age of first facial hair	1.1	2.2	7.0	-1.6	-1.2	-1.5	-1.6	-1.0	-1.5	-1.1	-1.1	-0.5	-2.1	-1.7	-1.6	-0.9	-0.7	-2.2	-2.6	-0.8	-1.4	-2.4	-0.8	-0.8	-1.1	-1.5	-1.5	-1.5	-1.7
Leg fat-free mass (left)	1.1	5.6	12.1	-1.9	-2.0	-2.5	-2.9	-2.5	-2.8	-2.1	-2.1	-1.2	-2.4	-2.5	-1.2	-2.6	-0.2	-2.5	-2.6	-1.8	-2.7	-3.5	-2.0	-1.9	-1.9	-2.9	-3.0	-2.6	-2.9
Happiness	1.1	1.3	3.0	0.5	-0.2	0.8	1.2	1.6	1.4	0.7	1.1	0.5	0.1	0.1	0.2	1.2	0.3	0.4	1.0	1.6	1.7	1.7	1.3	1.7	1.2	1.5	1.7	1.1	1.3
Length of working week for main job	1.1	1.2	4.1	0.0	1.1	1.0	1.2	0.3	0.9	0.3	0.7	1.9	1.5	1.9	-0.1	2.0	-0.1	1.6	1.6	-0.3	0.5	1.5	-0.4	0.1	0.2	1.1	0.9	0.9	1.0
Exposure to tobacco smoke at home	1.1	1.2	3.3	0.4	-0.5	-1.6	-1.4	-0.9	-0.8	-1.4	-1.2	-0.7	-1.8	-1.3	-0.5	-0.9	-1.6	-1.1	-1.7	-0.4	-1.0	-1.3	-0.4	-0.5	-0.9	-1.0	-1.0	-1.1	-1.1
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	6.5	-1.6	-2.2	-1.0	-1.3	-0.8	-0.6	-0.3	-1.0	-1.1	-2.1	-1.9	-0.6	-0.9	-1.1	-2.5	-0.6	0.9	-0.9	-0.9	-0.3	0.8	-1.1	-1.0	-0.9	-1.0	-0.3
Medication: Ibuprofen	1.1	1.3	5.6	0.1	0.3	0.8	1.0	1.5	1.2	0.4	1.5	0.9	0.0	0.4	-0.5	1.2	0.5	-0.8	0.2	1.8	1.3	0.6	2.1	2.4	1.4	1.3	1.1	1.5	1.3
Medication: Omeprazole	1.1	1.3	3.9	0.3	-0.1	0.3	1.0	1.1	1.5	1.8	0.7	0.2	0.7	1.0	0.5	2.0	0.1	0.8	1.1	0.8	1.4	1.8	1.2	1.2	1.1	1.3	1.4	1.1	1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	7.3	2.7	2.1	-0.4	0.2	0.7	0.6	-2.1	-0.1	0.8	0.3	0.6	1.4	-0.6	0.6	2.2	-0.5	-0.7	0.7	-0.6	0.8	-1.0	0.9	0.5	0.6	0.2	-0.3
Commuting to job workplace: Public transport	1.1	1.4	3.1	-0.8	-0.6	-1.4	-1.5	-1.5	-1.0	-0.9	-1.8	-0.1	-1.1	-0.9	-1.2	-1.1	0.0	-0.3	-0.9	-0.9	-1.4	-1.6	-1.7	-1.1	-1.4	-1.1	-1.3	-1.3	-1.2
Irritability	1.1	1.9	6.9	0.9	1.1	1.3	1.2	1.8	1.2	0.2	1.9	0.9	0.3	-0.1	1.6	1.0	1.0	-0.9	0.1	2.3	1.4	0.4	2.6	1.6	2.2	1.2	1.3	1.5	1.4
Lupus	1.0	1.5	3.8	0.7	-0.1	1.8	1.3	1.1	1.1	1.7	1.4	-0.0	1.3	0.8	-0.0	1.5	-0.4	0.6	1.8	1.1	1.1	1.9	1.2	1.5	0.6	1.1	1.1	1.6	1.6
Sensitivity / hurt feelings	1.0	1.6	4.9	-0.3	0.1	1.6	1.4	1.0	1.1	2.2	1.6	0.9	1.0	0.6	-0.1	1.6	1.0	-0.9	1.5	2.1	0.9	1.3	0.9	1.8	1.1	1.1	1.1	1.2	1.7
Ever had hysterectomy (womb removed)	1.0	1.1	2.8	0.6	1.2	1.1	1.4	1.4	1.0	-0.2	1.7	0.8	1.5	1.1	-0.2	1.3	0.5	1.5	0.5	0.2	1.3	1.2	1.0	0.4	1.2	1.1	1.1	0.9	0.5
Impedance of leg (right)	1.0	5.0	9.8	1.1	1.8	2.3	2.7	2.6	2.7	0.9	2.3	1.1	2.1	2.4	0.9	2.6	0.3	2.0	2.4	1.8	2.6	3.1	2.2	1.9	2.5	2.8	2.8	2.6	2.8
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.2	-0.6	-1.3	-0.6	-0.8	-0.7	-1.2	-1.8	-0.3	-1.0	-0.8	-1.0	-1.2	-0.9	-1.2	-1.3	-1.6	-0.7	-0.9	-1.6	-0.5	-0.4	-1.2	-1.2	-1.2	-1.0	-1.3
Leg predicted mass (left)	1.0	5.5	11.8	-1.8	-2.0	-2.5	-2.8	-2.5	-2.7	-2.1	-2.0	-1.1	-2.3	-2.4	-1.2	-2.5	-0.2	-2.4	-2.5	-1.8	-2.7	-3.4	-2.0	-1.9	-1.9	-2.9	-3.0	-2.6	-2.8
Pulse rate	1.0	1.7	5.3	0.2	0.1	-2.3	-1.7	-1.2	-1.1	-1.9	-1.9	0.8	-1.4	-0.8	0.7	-0.5	-0.6	0.1	-1.6	-1.4	-1.4	-1.8	-1.2	-1.7	-1.1	-1.2	-1.2	-1.2	-1.3
Hair/balding pattern: Pattern 4	1.0	2.5	4.6	-0.9	-1.1	-1.9	-2.0	-2.1	-1.9	-0.1	-2.1	-1.2	-1.8	-1.9	-0.1	-1.3	-0.5	-1.0	-0.9	-1.5	-2.1	-1.1	-2.0	-1.6	-1.9	-1.7	-1.9	-1.9	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	3.8	0.8	0.5	0.3	1.0	0.9	1.5	1.9	0.4	0.8	1.0	1.2	1.1	1.9	0.2	1.3	1.4	0.6	1.1	1.6	0.7	0.8	0.9	1.3	1.4	1.0	1.4
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	3.0	-0.6	-1.0	-1.7	-1.2	-1.3	-0.7	-0.1	-1.4	-0.8	-1.6	-1.2	-0.2	-1.3	-1.7	-1.1	-0.6	-0.1	-1.2	-1.0	-1.3	-0.2	-1.4	-1.0	-1.0	-1.3	-0.8
Bipolar Disorder (2011)	0.9	0.9	2.3	1.3	1.4	0.6	1.4	0.8	0.9	1.5	1.1	0.6	1.5	0.6	0.8	0.1	0.3	0.8	0.5	0.9	0.9	1.2	0.7	1.0	0.4	1.0	1.0	0.6	0.8
Systolic blood pressure, automated reading	0.9	2.7	6.1	-1.5	-1.4	1.5	1.4	1.9	1.7	1.2	1.6	-0.8	0.1	0.4	-1.4	1.7	-0.5	-1.4	1.4	2.4	1.8	2.3	2.1	2.5	2.0	1.7	1.6	1.5	2.1
Medication: Simvastatin	0.9	1.3	2.7	0.5	0.7	1.4	1.1	1.1	1.5	1.6	1.2	0.7	0.8	0.7	0.8	0.3	1.0	0.1	1.3	1.6	1.1	1.0	1.3	1.4	1.5	1.3	1.1	1.2	1.3
Number of live births	0.9	1.2	13.1	2.9	1.8	-0.2	0.0	0.3	0.5	-1.3	0.1	1.4	0.2	-0.3	3.6	-0.5	0.1	0.8	0.4	0.7	0.1	-0.6	0.8	-0.1	0.6	0.3	0.3	0.4	0.2
Leg fat-free mass (right)	0.9	4.7	10.6	-1.8	-1.9	-2.3	-2.6	-2.4	-2.5	-1.8	-1.9	-1.0	-2.3	-2.4	-1.1	-2.4	0.0	-2.5	-2.2	-1.4	-2.5	-3.2	-1.9	-1.6	-1.8	-2.7	-2.8	-2.4	-2.6
Leg predicted mass (right)	0.9	4.7	10.4	-1.8	-1.9	-2.3	-2.6	-2.4	-2.5	-1.9	-1.9	-1.0	-2.2	-2.4	-1.1	-2.4	0.0	-2.5	-2.2	-1.5	-2.5	-3.2	-1.9	-1.6	-1.8	-2.7	-2.7	-2.4	-2.6
Average weekly champagne plus white wine intake	0.9	1.2	4.0	-0.5	1.0	1.0	1.2	1.6	1.0	-0.0	1.2	0.9	1.2	1.3	-0.1	1.7	1.7	1.1	-0.0	0.2	1.2	0.5	1.2	-0.3	2.0	1.1	1.3	1.1	0.8
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.7	-0.5	-0.3	1.6	1.2	1.3	0.7	1.2	1.6	-0.7	0.8	0.5	-1.2	0.0	0.8	-0.4	0.8	0.8	1.3	1.1	1.4	1.5	1.2	0.9	1.0	1.1	0.7
Fractured/broken bones in last 5 years	0.9	1.1	3.2	0.3	0.3	1.6	1.2	0.6	0.8	1.0	1.0	0.6	1.5	1.7	-0.7	1.2	1.2	0.8	1.8	0.0	0.9	1.6	0.4	0.6	0.9	1.0	1.0	1.2	1.2
Bipolar Disorder (2018)	0.8	1.3	7.9	-0.1	-0.9	-0.6	-0.9	-1.4	-1.0	-0.7	-1.0	-1.3	-0.9	-1.3	-0.3	-1.4	-2.8	-1.3	-0.6	-0.1	-1.3	-0.2	-1.2	-0.2	-1.8	-1.0	-1.1	-1.0	-0.6
Schizophrenia (2018)	0.8	1.6	4.1	-0.9	-1.1	-1.1	-1.3	-1.3	-1.3	-0.5	-1.4	-1.2	-1.9	-1.5	-0.8	-1.3	-2.0	-1.1	-1.6	-0.8	-1.4	-0.8	-1.1	-0.9	-1.3	-1.2	-1.2	-1.5	-1.3
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	4.9	1.6	1.6	0.6	0.5	0.3	0.4	0.3	0.7	1.6	0.7	0.5	2.2	-0.4	1.8	0.6	0.6	0.7	0.3	-0.7	0.5	0.5	0.3	0.4	0.4	0.7	0.3
Body mass index (BMI)	0.8	3.4	5.9	-0.1	-1.2	-2.3	-2.4	-2.2	-2.0	-0.9	-2.1	-0.7	-1.6	-1.8	-0.0	-2.1	-0.4	-1.1	-2.2	-1.7	-2.2	-2.3	-1.8	-1.6	-2.1	-2.1	-2.3	-2.1	-2.4
Fluid intelligence score	0.8	1.6	6.3	-1.4	-0.7	-1.4	-1.1	-0.7	-0.8	-0.5	-0.7	-0.9	-0.9	-1.0	-1.7	-0.9	-2.5	-0.4	-2.1	-1.7	-0.9	-1.9	-0.7	-1.4	-0.6	-1.1	-1.2	-1.6	-1.7
Worrier / anxious feelings	0.8	1.5	3.2	0.3	0.7	1.6	1.6	1.2	1.1	0.9	1.6	1.8	1.4	1.4	-0.1	1.5	1.6	0.4	1.2	1.1	1.1	1.3	0.9	0.8	1.5	1.3	1.3	1.3	1.2
Noisy workplace	0.8	1.0	4.2	-0.3	-0.2	0.6	0.8	1.0	1.4	2.1	0.9	-0.8	0.1	-0.2	0.7	-0.1	-0.1	-0.2	1.1	1.4	1.0	1.6	1.4	1.7	0.9	1.3	0.9	0.4	0.9
Medication: Allopurinol	0.8	1.0	3.8	-0.2	-0.2	0.4	0.7	1.3	1.3	1.0	0.8	0.6	0.3	1.0	-0.9	0.8	0.9	-0.0	0.7	1.2	1.3	0.7	1.4	1.2	1.9	1.3	1.1	1.1	1.1
Supplements: Vitamin C	0.8	0.9	4.0	0.3	-0.2	1.6	1.2	0.5	0.4	0.3	1.4	-0.1	0.7	-0.1	0.9	0.0	-0.0	-1.4	1.5	1.9	0.6	1.1	0.8	2.0	-0.0	0.6	0.6	1.0	1.2
Mineral and other dietary supplements	0.8	1.0	4.3	0.6	-0.2	-1.6	-0.9	-0.3	-0.2	-0.8	-1.3	-0.7	-1.1	-0.5	-1.1	-0.9	-2.1	1.2	-1.5	-1.7	-0.1	-0.5	-0.4	-1.2	-0.8	-0.4	-0.3	-1.1	-1.3
Smoking status: Current	0.8	1.2	5.3	-0.4	-0.3	-0.9	-1.0	-1.0	-1.3	-1.1	-1.2	0.3	-0.5	0.3	-1.7	-0.2	0.5	0.4	-1.5	-2.3	-1.0	-1.3	-1.4	-1.9	-0.6	-1.1	-1.1	-0.7	-1.4
High cholesterol (Self-reported)	0.8	1.4	3.5	0.7	0.2	1.2	1.2	1.2	1.5	1.6	1.4	-0.1	0.7	0.4	1.2	0.6	0.2	-0.1	1.2	1.9	1.2	1.4	1.8	1.8	1.1	1.4	1.2	1.1	1.5
Alzheimer’s Disease (in mother)	0.7	0.8	2.8	-0.3	-0.1	-0.9	-0.6	-1.2	-0.8	0.4	-1.0	-0.3	0.1	0.1	-0.4	-1.3	0.9	0.3	0.4	-1.3	-1.0	-1.0	-1.7	-1.3	-1.2	-0.9	-0.9	-1.1	-1.0
Allergy or Eczema	0.7	1.8	5.0	0.6	1.0	1.1	1.5	0.9	1.3	1.7	1.1	1.2	2.2	1.9	0.7	2.2	1.1	2.0	1.5	-0.1	1.0	2.0	0.4	-0.0	1.0	1.3	1.3	1.2	1.3
Number of treatments/medications taken	0.7	1.2	5.2	-0.8	-0.9	0.2	0.2	0.9	1.6	1.8	0.2	0.3	-0.5	0.5	0.2	1.1	0.5	-0.6	1.2	2.3	0.9	0.9	1.4	2.1	0.9	1.1	0.9	0.8	1.5
Angina	0.7	0.9	3.9	1.2	0.8	0.1	0.6	0.3	1.0	2.0	0.3	1.2	0.4	0.4	1.2	-0.4	1.2	-0.0	1.5	1.9	0.7	0.4	0.4	1.6	0.3	0.7	0.8	0.6	1.0
Medication for hormone replacement therapy	0.7	0.7	4.4	0.2	-0.2	-0.7	-1.0	-0.4	-1.0	-2.1	-0.3	-0.3	-0.7	-0.7	-1.2	-0.3	-0.6	-0.5	-1.8	-0.7	-0.6	-1.3	0.0	-0.2	-0.6	-0.8	-0.9	-0.4	-1.1
Current tobacco smoking	0.7	1.1	4.4	-0.2	-0.3	-1.1	-1.0	-1.0	-1.2	-1.1	-1.2	0.1	-0.5	0.2	-1.6	-0.3	0.4	0.5	-1.4	-2.1	-1.0	-1.2	-1.4	-1.8	-0.7	-1.0	-1.0	-0.8	-1.4
Medication: Ramipril	0.7	1.0	5.0	-1.6	-1.6	-0.3	-0.9	-1.0	-0.7	0.9	-0.8	-0.6	-0.9	-1.1	-0.2	-0.6	-0.5	-2.2	0.4	0.7	-1.0	-0.7	-0.9	0.7	-1.5	-0.9	-0.9	-0.6	-0.2
Mouth/teeth dental problems: Dentures	0.7	1.2	5.2	1.6	1.2	0.7	0.8	0.5	0.8	0.7	0.4	1.3	1.6	1.4	2.3	0.6	1.5	1.8	1.2	0.4	0.7	0.9	0.4	0.1	0.6	0.8	0.9	1.0	0.9
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	6.6	-1.9	-1.9	0.5	0.1	-0.3	-0.4	-0.8	0.6	-2.2	-0.7	-0.6	-1.5	0.0	-2.6	-1.6	-0.1	0.3	-0.4	0.8	0.2	0.5	-0.4	-0.4	-0.4	-0.4	0.2
Number of full brothers	0.7	0.9	3.9	0.1	0.1	-1.4	-1.1	-1.1	-0.7	-0.4	-1.4	-0.3	-0.6	-0.3	0.9	-0.4	0.4	0.5	-0.6	-1.7	-1.2	-1.0	-1.2	-2.0	-0.5	-0.9	-1.0	-1.1	-1.1
Number of children fathered	0.7	0.7	6.4	1.8	0.8	-0.5	0.1	-0.3	0.2	-0.6	-0.4	-0.0	1.2	1.1	-0.2	0.1	0.5	2.5	0.3	-1.6	0.0	0.5	-0.8	-1.1	-0.3	0.1	0.2	0.0	-0.3
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.9	0.0	-1.0	-1.2	-1.0	-1.3	-1.0	-0.6	-1.2	-0.7	-0.9	-1.2	-0.7	-0.5	-1.0	-0.9	-0.3	-0.3	-1.2	-0.5	-1.2	-0.6	-1.4	-1.0	-1.0	-0.8	-0.5
Angina (self-reported)	0.7	1.0	4.8	1.0	0.7	0.1	0.6	0.4	1.1	2.2	0.3	1.1	0.4	0.4	1.1	-0.4	1.2	-0.1	1.6	2.0	0.7	0.5	0.5	1.5	0.4	0.8	0.9	0.5	1.0
Heart disease (mother)	0.7	0.8	2.9	-0.0	0.8	-0.9	-0.7	-1.1	-0.6	-0.5	-0.9	0.5	0.4	0.5	0.9	-1.2	-0.1	1.1	-0.4	-1.4	-1.0	-1.4	-1.1	-1.7	-0.9	-0.9	-1.0	-1.0	-0.9
Loneliness, isolation	0.7	1.0	2.9	-1.3	-1.1	-1.4	-1.1	-0.8	-1.0	-0.3	-1.1	-1.2	-1.2	-0.5	-1.7	-0.4	-0.4	-0.0	-1.1	-1.4	-0.7	-0.8	-1.0	-0.9	-0.8	-0.9	-0.8	-1.1	-1.1
Supplements: Fish oil (including cod liver oil)	0.7	1.0	3.9	-0.5	-0.2	1.7	0.8	0.0	0.1	0.6	1.1	0.2	0.7	0.3	1.2	0.3	0.9	-1.6	1.9	2.0	-0.1	0.9	0.3	1.5	0.4	0.3	0.2	1.0	1.4
Alcohol drinker status: Never	0.7	0.8	3.1	0.6	0.4	0.5	0.9	1.2	0.9	1.8	1.0	0.1	1.1	0.7	-0.1	0.7	0.7	0.8	0.8	0.4	1.2	0.8	1.2	0.7	1.2	1.0	1.0	0.9	0.7
Heart disease (siblings)	0.7	0.9	10.0	-0.4	-0.4	0.7	0.6	0.5	0.9	3.2	0.7	0.0	0.6	0.4	0.4	0.8	1.5	-0.2	0.9	1.0	0.5	0.9	0.5	0.7	1.0	0.8	0.6	0.4	0.9
HbA1C	0.6	0.7	2.2	1.1	1.0	0.5	0.8	0.7	0.8	0.2	1.2	1.2	0.6	0.4	0.6	0.4	0.9	-0.3	1.0	1.5	0.6	-0.5	1.1	1.0	0.9	0.8	0.6	0.7	0.8
Average weekly spirits intake	0.6	0.7	1.7	1.0	0.6	1.0	0.8	1.0	0.3	0.1	1.1	0.5	1.0	0.9	-0.9	1.3	0.8	1.3	-0.1	-0.6	0.9	0.9	1.0	0.2	1.0	0.6	0.6	1.3	0.3
Supplements: Zinc	0.6	0.6	2.5	0.6	0.2	-0.9	-0.5	-1.0	-0.8	0.1	-0.9	1.5	0.3	-0.1	0.1	0.3	1.6	0.4	0.2	-0.8	-0.9	-0.7	-1.5	-1.0	-0.6	-0.6	-0.6	-0.3	-0.5
Pack years adult smoking proportion	0.6	1.0	2.8	-0.2	-0.1	-1.2	-1.2	-1.3	-1.0	-0.9	-1.3	0.1	-1.0	-0.6	-0.0	-1.7	-0.3	-0.7	-0.9	-0.7	-1.2	-1.3	-1.1	-1.0	-1.0	-1.2	-1.2	-1.0	-0.9
Maternal smoking around birth	0.6	0.8	2.9	-0.8	-0.8	0.6	0.3	0.9	1.0	0.6	0.1	-0.5	0.3	1.6	-0.5	1.7	-0.4	1.1	1.2	-0.3	1.0	1.3	0.8	0.4	0.7	1.0	0.9	0.9	1.1
Time employed in main current job	0.6	0.7	1.4	0.9	-0.6	-1.1	-0.9	-0.9	-0.8	-0.7	-1.1	-0.2	-0.1	-0.8	-0.3	-1.1	-0.1	0.8	-0.8	-1.1	-0.5	-0.3	-1.0	-0.5	-1.2	-1.0	-0.8	-0.8	-0.9
Hair/balding pattern: Pattern 3	0.6	0.9	2.8	1.3	1.4	0.9	0.9	1.5	0.8	-0.3	1.5	0.8	0.7	0.5	0.2	-0.2	0.3	0.1	-1.1	0.7	1.2	-0.9	1.7	0.6	1.6	0.7	0.8	0.8	0.0
Loud music exposure frequency	0.6	0.7	2.9	-0.4	-0.4	1.0	0.7	0.4	0.5	1.6	1.0	0.7	0.4	-0.1	0.3	1.1	1.7	-1.0	0.8	1.5	0.4	0.5	0.5	1.4	0.2	0.5	0.4	0.6	0.8
Eye problems/disorders: None of the above	0.6	0.7	2.5	-1.5	-1.0	0.5	0.4	0.5	0.5	0.7	0.9	-0.3	-0.5	-0.6	-0.9	0.7	-1.0	-1.6	0.0	1.5	0.2	0.4	0.9	1.6	-0.1	0.4	0.1	0.1	0.4
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.2	0.9	0.4	1.2	0.9	1.1	0.6	-0.8	1.3	-0.4	0.7	0.6	0.9	0.5	-0.4	0.1	0.4	0.5	1.1	0.8	1.5	0.9	0.9	0.8	0.9	0.9	0.7
Friendships satisfaction	0.6	0.7	3.9	-1.2	-1.5	-1.1	-0.5	-0.3	-0.2	-1.1	-0.7	-1.1	-1.8	-1.2	-0.6	0.2	-2.0	-1.0	0.2	0.3	-0.3	0.2	-0.6	-0.2	-0.2	-0.3	-0.1	-0.7	0.1
Wears glasses or contact lenses	0.6	0.7	2.6	1.0	0.9	-0.3	-0.6	-0.9	-1.1	-1.6	-0.2	0.0	-0.1	-0.7	0.3	-0.8	0.3	-0.2	-1.1	-1.1	-0.8	-1.2	-0.4	-0.8	-0.5	-0.8	-1.0	-0.4	-1.1
Hearing aid user	0.6	0.7	2.7	-0.4	0.5	0.7	0.9	1.0	0.9	-0.0	0.8	0.1	0.8	0.9	0.8	0.3	1.1	0.7	1.6	0.5	1.0	0.8	0.7	0.2	1.1	0.8	1.0	0.6	0.7
Eye problems/disorders: Glaucoma	0.6	0.7	1.7	0.3	-0.6	-1.3	-1.2	-0.9	-0.6	-1.1	-1.3	-1.0	-1.2	-1.1	0.2	-0.7	-0.7	-0.4	-0.8	-0.4	-0.9	-0.3	-0.5	-1.0	-0.6	-0.8	-0.7	-0.9	-0.5
Medication: Blood pressure	0.6	1.2	4.9	0.1	-1.3	-1.5	-1.7	-0.9	-0.8	-0.6	-1.5	-0.8	-1.7	-1.8	-0.2	-0.9	-2.2	-0.4	-1.3	-0.4	-0.9	-0.5	-0.3	-0.5	-0.9	-1.0	-1.1	-0.9	-0.8
Medication: Atorvastatin	0.6	0.7	4.9	0.7	0.8	0.1	0.6	0.5	1.0	0.0	-0.2	1.1	1.0	1.6	0.8	1.2	0.2	2.2	1.1	-0.2	0.7	1.0	-0.1	-0.3	0.3	0.8	0.8	0.4	0.6
Depressed Affect (Nagel 2018)	0.5	1.0	2.8	0.7	0.1	1.1	1.0	0.8	0.6	0.9	0.8	0.8	1.3	1.6	-1.5	1.7	0.1	0.9	1.1	0.1	1.0	1.3	0.6	0.9	0.6	0.8	1.0	1.5	1.3
Ovarian Cancer	0.5	0.6	2.0	-0.2	0.1	0.0	-0.7	-1.0	-1.4	-0.0	-0.2	0.1	-0.3	-1.0	0.1	-0.8	0.6	-1.3	-0.6	-0.5	-1.2	-1.1	-1.0	-0.9	-0.5	-1.1	-1.1	-0.6	-1.1
Mean Putamen Volume	0.5	0.6	3.2	0.2	0.4	-1.3	-0.6	-0.3	-0.1	-1.8	-0.6	-0.4	0.2	-0.2	-0.1	-0.8	-0.8	1.2	-1.1	-1.2	-0.2	-0.6	-0.2	-0.7	-0.7	-0.4	-0.5	-1.0	-1.1
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	0.7	0.4	1.0	1.1	0.8	0.4	-0.1	1.0	-0.4	1.1	0.2	1.6	-0.6	0.2	0.1	0.7	1.0	1.0	0.7	0.6	0.8	0.4	0.4	1.0	0.5	0.8
Vitamin and mineral supplements	0.5	0.6	3.6	1.5	0.4	-0.7	0.1	0.3	1.2	1.6	-0.7	-0.1	0.2	0.5	0.5	0.1	0.2	1.9	0.8	-0.1	0.7	1.2	0.0	-0.2	0.4	0.9	0.9	0.0	0.5
Taking other prescription medications	0.5	0.7	3.7	-0.8	-1.0	0.1	0.2	0.3	1.0	1.9	-0.2	-0.5	-0.0	0.3	-0.1	0.7	1.0	-0.6	1.2	1.5	0.6	1.0	0.7	1.5	0.1	0.7	0.7	0.5	1.3
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.5	1.1	1.2	0.8	1.2	0.6	0.9	1.2	0.9	0.9	1.9	1.3	1.2	1.5	0.6	1.7	0.9	-0.3	0.7	1.6	0.4	-0.0	0.6	0.9	1.0	0.9	0.9
Supplements: Glucosamine	0.5	0.6	1.4	-0.4	0.5	1.0	1.0	0.7	0.6	-0.8	1.1	0.8	0.9	0.8	0.9	1.2	0.9	-0.2	1.0	0.5	0.6	0.4	0.7	0.7	1.1	0.6	0.6	0.9	0.8
Medication: Atenolol	0.5	0.7	6.6	-1.6	-1.3	0.1	-0.1	0.4	0.1	2.6	0.2	-0.1	-0.5	-0.1	-1.9	0.2	0.3	-1.1	-0.2	0.7	0.3	-0.2	0.3	0.5	0.8	0.0	0.0	0.0	0.1
Nervous feelings	0.5	1.0	3.0	-1.3	-0.9	1.1	0.8	0.9	0.2	1.5	1.1	0.5	0.1	0.1	-1.0	1.3	1.3	-1.7	0.6	1.6	0.6	0.5	0.8	1.4	0.9	0.5	0.6	0.8	0.9
Hair/balding pattern: Pattern 2	0.5	0.6	2.3	0.6	-0.6	-1.5	-0.8	-1.0	-0.0	-0.1	-1.4	0.2	-0.8	-0.7	1.5	-0.5	-0.0	0.3	1.0	0.2	-0.6	0.4	-1.0	0.3	-1.2	-0.2	-0.4	-0.8	-0.1
Mouth/teeth dental problems	0.5	0.8	2.1	0.3	1.4	1.2	1.2	0.8	0.5	0.6	1.3	1.1	1.3	1.4	-1.0	0.8	1.2	1.0	0.5	-0.4	0.8	0.5	0.3	-0.1	1.1	0.8	0.7	0.7	0.2
Illnesses of siblings	0.5	0.7	2.9	-0.3	-0.9	-0.8	-0.6	-0.6	-0.8	-1.3	-0.7	-1.3	-0.9	-0.6	-1.7	-0.6	-0.9	-0.1	-0.8	-1.3	-0.6	-0.2	-0.6	-0.5	-1.1	-0.7	-0.6	-0.7	-0.9
Weight	0.5	2.4	5.4	-0.8	-1.2	-1.8	-2.0	-1.7	-1.6	-1.2	-1.4	-0.7	-1.6	-1.8	-0.2	-1.9	-0.3	-1.7	-1.9	-0.8	-1.8	-2.3	-1.1	-1.0	-1.4	-1.9	-2.0	-1.8	-1.9
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	3.0	-0.0	-0.7	-0.8	-0.6	-0.8	-0.4	-0.9	-0.6	-1.2	-0.4	-0.5	0.4	-0.6	-1.7	0.1	-0.2	-0.9	-0.6	0.2	-0.5	-0.3	-1.2	-0.6	-0.6	-0.9	-0.6
Depression (self-reported)	0.5	0.6	3.9	-1.6	-1.4	0.6	0.1	-0.4	-0.1	1.1	-0.1	-0.4	-0.3	0.7	-2.0	0.9	0.3	-0.5	1.0	-0.2	-0.3	0.5	-0.6	0.2	-0.1	0.0	-0.1	0.3	0.5
Breastfed as a baby	0.5	0.6	4.4	2.1	1.7	0.2	0.4	0.6	0.9	0.2	0.3	0.8	0.5	0.3	0.7	-1.0	0.1	1.0	-0.0	0.6	0.7	-0.8	0.5	0.1	0.8	0.4	0.5	0.2	-0.1
Worry too long after embarrassment	0.5	0.9	2.5	0.6	0.0	1.2	1.3	1.0	0.9	1.5	1.3	0.2	0.9	0.7	0.3	1.6	0.2	0.3	1.1	0.8	0.9	1.3	0.7	0.4	0.9	0.9	1.1	0.8	1.1
Neck or shoulder pain in last month	0.5	0.7	2.6	0.0	-0.3	-1.0	-1.1	-0.6	-0.8	-0.1	-0.9	-0.7	-1.1	-0.8	-0.3	-1.1	-0.4	-0.6	-1.6	-0.5	-0.7	-1.5	-0.3	-0.7	-0.7	-0.9	-0.8	-0.9	-1.0
Overall health rating	0.5	1.1	3.1	-0.7	-1.8	-1.6	-1.1	-1.2	-0.6	1.5	-1.4	-0.9	-1.1	-0.7	-1.3	-1.4	0.1	-0.7	-0.6	-0.0	-0.7	-0.8	-1.0	0.3	-1.5	-0.9	-0.8	-1.1	-0.6
Knee pain experienced in last month	0.5	0.8	2.9	0.3	0.2	-0.2	-0.6	-1.1	-1.1	-0.0	-0.3	-0.3	-0.2	-0.7	0.4	-1.7	0.2	-0.4	-1.2	-0.9	-1.2	-1.1	-0.9	-0.9	-0.9	-1.0	-1.1	-1.0	-1.4
Illnesses of siblings: Diabetes	0.5	0.6	2.0	1.0	1.1	0.8	0.7	0.9	0.3	1.4	1.2	0.9	0.9	-0.3	0.4	0.3	1.0	-0.2	-0.5	0.9	0.6	-0.4	1.0	0.6	1.0	0.6	0.4	0.6	0.2
Qualifications: nursing, teaching	0.5	0.7	4.3	-1.0	-0.9	0.3	-0.1	-0.1	-0.0	-0.8	0.2	-0.7	-1.3	-1.1	-1.0	-0.4	-2.1	-1.8	0.5	1.4	-0.1	0.1	0.3	1.4	-0.3	-0.1	0.0	-0.1	0.6
Breast cancer (self-reported)	0.5	0.6	3.2	-0.1	0.5	-0.0	0.6	0.2	0.6	1.8	0.2	1.4	1.0	1.1	0.1	1.2	1.1	1.0	0.6	0.3	0.5	0.9	-0.1	0.6	-0.0	0.7	0.5	0.5	0.6
Osteoarthritis (self-reported)	0.5	0.6	4.2	2.0	1.2	-0.2	0.0	0.1	0.4	1.1	-0.0	0.8	0.2	-0.5	2.0	-0.9	1.6	0.4	0.2	0.9	0.1	-0.4	0.3	0.4	0.3	0.3	0.3	-0.0	0.1
Medication: Aspirin	0.5	0.6	2.8	0.4	-0.4	-1.1	-1.2	-0.9	-0.2	-0.6	-1.7	-0.2	-1.2	-0.2	0.3	-1.3	-0.6	0.2	0.1	0.1	-0.7	-0.6	-1.1	-0.4	-1.1	-0.5	-0.5	-0.9	-0.6
Illnesses of father: None of the above (group 1)	0.5	0.7	2.0	-0.7	-0.3	-0.1	-0.9	-1.3	-1.1	-0.2	-1.0	-0.2	-0.8	-0.4	-0.4	-1.4	0.2	-0.8	-0.2	-0.5	-1.2	-0.9	-1.3	-0.6	-0.9	-0.8	-1.1	-0.8	-0.7
Unable to work because of sickness or disability	0.5	0.6	2.0	-0.2	-0.2	-0.7	-0.9	-0.7	-0.7	-0.6	-0.7	-0.2	-0.2	-0.2	-0.6	-1.1	0.7	0.1	-1.3	-1.1	-0.7	-1.4	-0.6	-0.8	-0.3	-0.8	-1.0	-0.8	-1.2
Ulcerative Colitis (UC)	0.4	0.8	2.5	-0.9	-0.9	-0.5	-0.6	-0.9	-0.9	-1.0	-0.4	-0.9	-0.6	-1.0	-1.6	-0.8	-1.3	-0.6	-0.7	-0.8	-1.0	-0.3	-1.1	-0.7	-0.8	-0.9	-1.1	-1.2	-1.1
Major Depression (MDD)	0.4	0.5	2.0	0.3	-0.5	0.2	0.6	0.3	1.0	1.4	0.4	-0.3	0.5	-0.1	0.3	0.5	-0.8	0.8	1.4	0.7	0.4	1.3	0.4	0.6	0.1	0.8	0.6	0.2	0.9
Systolic Blood Pressure	0.4	1.9	5.6	-1.0	-1.0	0.8	1.1	1.8	1.7	-0.1	1.3	-0.2	-0.2	-0.0	-0.4	1.5	-0.5	-1.2	0.7	2.4	1.7	1.4	2.1	2.4	1.7	1.4	1.4	1.2	1.8
Hearing difficulty/problems: Yes	0.4	0.6	3.0	0.7	0.2	0.9	0.9	0.9	0.8	0.6	0.7	-0.1	1.1	0.7	-0.1	1.0	-0.3	1.3	0.4	-0.2	1.0	1.7	0.6	0.6	0.1	1.0	1.1	0.7	0.5
Medication: Co-codamol	0.4	0.5	6.2	-0.5	0.4	-0.1	-0.4	-0.1	-0.5	1.3	0.0	0.1	-0.1	-0.1	-0.7	-0.3	2.5	-0.3	-1.0	-0.4	-0.2	-1.1	0.0	-0.2	-0.0	-0.3	-0.4	-0.2	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.8	-0.6	-1.3	-0.7	-0.7	-0.3	-0.5	-1.0	-0.7	-1.0	-1.3	-0.7	-0.6	-0.3	-1.3	-0.8	-0.7	-0.4	-0.3	-0.1	-0.1	0.4	-0.8	-0.4	-0.3	-0.5	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.0	-0.7	-0.8	-0.7	-1.0	-0.8	-0.9	-0.6	-0.9	-0.7	-1.4	-0.4	-0.9	-0.3	-0.9	-0.7	-1.1	-0.8	-1.0	-0.6	-0.7	-1.0	-0.4	-0.8	-0.9	-0.8	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.3	0.1	-1.4	-0.7	-0.4	-0.8	-0.3	-1.3	-1.1	-2.0	0.2	0.2	-0.5	0.7	-2.1	0.9	0.5	-1.1	-0.3	1.3	-0.8	-0.1	-1.6	-0.3	-0.2	-0.1	0.3
Qualifications: None of the above	0.4	0.8	7.1	1.5	1.1	0.8	0.3	0.4	0.5	1.1	0.4	0.7	0.1	-0.2	2.7	-0.6	1.3	-0.3	0.3	1.5	0.2	0.0	0.7	0.5	0.5	0.4	0.4	0.6	0.7
Diabetes (self-reported)	0.4	0.6	1.6	0.7	0.3	1.2	0.6	0.8	0.5	-0.3	0.9	0.1	0.5	0.5	0.6	0.6	0.6	0.0	0.6	1.0	0.8	1.0	1.2	1.1	0.7	0.7	0.7	1.2	1.0
Hip circumference	0.4	1.8	3.5	-0.8	-0.8	-1.8	-1.7	-1.7	-1.4	-1.0	-1.4	-0.4	-1.0	-1.2	-0.1	-1.4	-0.3	-0.8	-1.4	-1.3	-1.7	-1.9	-1.3	-1.2	-1.6	-1.5	-1.8	-1.7	-1.8
Alcohol intake versus 10 years previously	0.4	0.6	6.5	-1.2	-0.9	0.4	0.3	0.3	0.7	2.5	0.5	-0.3	-0.2	0.0	-0.2	0.6	0.4	-0.6	0.8	1.1	0.3	0.7	0.4	1.2	0.2	0.6	0.3	0.0	0.7
Blood clot in the leg (DVT)	0.4	0.5	1.4	-0.5	-0.7	-1.1	-0.7	-0.8	-0.2	0.7	-0.9	-0.4	-1.2	-0.8	0.2	-0.8	-1.2	-1.2	0.0	0.6	-0.7	-0.5	-0.7	0.4	-0.9	-0.5	-0.5	-0.7	-0.1
Birth weight	0.4	0.9	3.5	1.3	1.9	0.2	0.6	0.2	0.7	0.1	0.0	1.7	1.4	1.2	1.6	-0.4	1.3	1.7	0.8	0.3	0.5	-0.3	-0.1	-0.4	0.6	0.4	0.6	0.6	0.4
Comparative body size at age 10	0.4	1.0	6.6	-1.7	-2.6	-0.2	-0.1	0.3	0.7	1.9	0.0	-1.3	-0.7	-0.7	-1.2	-0.0	-1.0	-1.1	0.4	1.2	0.5	0.8	0.5	1.7	-0.2	0.4	0.3	-0.1	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.8	-0.8	-1.3	0.0	-0.4	-0.9	-1.1	0.5	-0.5	-0.2	-0.6	0.1	-1.1	0.2	0.3	-0.8	0.0	-0.7	-0.8	0.0	-1.1	-0.2	-0.9	-0.7	-0.6	-0.2	-0.3
Shortness of breath walking on level ground	0.4	0.5	4.9	0.8	0.0	-0.7	-0.6	-0.2	-0.2	0.2	-0.3	0.3	-0.7	-1.1	2.2	-0.6	1.2	-0.5	-0.7	0.2	-0.4	-0.5	0.2	0.0	0.0	-0.3	-0.3	-0.5	-0.5
Medication: Blood pressure	0.4	0.7	3.7	-0.3	0.3	0.8	0.9	0.4	1.0	0.4	0.7	0.4	1.1	1.2	0.7	-0.2	0.9	0.3	1.9	1.0	0.8	0.7	0.3	1.0	0.3	0.7	0.7	0.6	0.9
Leg fat mass (right)	0.4	1.7	3.3	-0.3	-1.2	-1.6	-1.8	-1.5	-1.3	-0.8	-1.4	-0.8	-1.4	-1.4	-0.2	-1.6	-0.3	-1.0	-1.7	-1.1	-1.5	-1.6	-0.9	-0.9	-1.2	-1.5	-1.7	-1.5	-1.7
Pulse rate, automated reading	0.4	1.3	3.4	0.6	0.1	-1.9	-1.3	-1.2	-0.9	-1.9	-1.6	-0.1	-1.2	-1.0	0.5	-1.4	-1.4	0.1	-1.0	-0.9	-1.3	-1.0	-1.2	-1.5	-1.1	-1.0	-1.0	-1.2	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.8	0.3	0.1	0.2	0.4	0.8	1.1	1.1	0.1	-0.3	0.3	0.4	1.4	0.5	1.3	0.5	0.5	0.8	0.9	0.6	1.0	0.6	0.9	0.7	0.9	0.7	1.0
Medication: Gliclazide	0.4	0.5	2.3	0.7	0.2	0.7	0.7	0.7	0.8	0.9	0.8	-0.1	0.6	0.2	1.5	-0.3	-0.2	-0.0	0.9	0.9	0.7	0.8	1.0	1.0	0.4	0.5	0.6	0.4	0.7
Arm fat mass (left)	0.4	1.5	2.7	-0.7	-1.5	-1.6	-1.6	-1.5	-1.2	-0.1	-1.3	-0.9	-1.4	-1.4	-0.4	-1.5	-0.4	-1.3	-1.3	-0.6	-1.4	-1.3	-1.1	-0.5	-1.4	-1.4	-1.5	-1.5	-1.4
Guilty feelings	0.4	0.5	2.0	-1.1	-1.4	-0.1	-0.6	-0.7	-0.8	0.7	-0.4	-1.0	-1.2	-1.0	-0.0	0.0	-0.8	-1.4	-0.3	0.1	-0.8	0.2	-0.4	-0.1	-0.7	-0.7	-0.6	-0.5	0.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	0.4	-0.1	-1.1	-0.8	-0.3	-0.2	-0.6	-1.1	-0.7	-1.1	-0.8	0.7	-0.9	-1.3	0.5	-1.1	-0.5	-0.3	-0.3	-0.2	-0.4	-0.8	-0.3	-0.3	-0.9	-0.7
Medication: Bendroflumethiazide	0.4	0.6	5.6	-0.7	-1.4	-0.1	-0.4	-0.5	-0.3	-0.8	-0.1	-0.7	-0.9	-1.1	0.2	-0.7	-2.4	-1.3	-0.3	0.7	-0.5	0.2	-0.1	0.7	-0.8	-0.3	-0.5	-0.7	-0.3
Ever smoked	0.4	0.7	2.0	0.9	1.0	-0.1	-0.7	-0.6	-0.9	-1.3	-0.6	0.9	-0.4	-0.1	0.1	-0.5	1.1	0.2	-1.3	-1.0	-0.8	-1.4	-0.5	-1.4	-0.0	-0.8	-0.8	-0.1	-0.8
Age started oral contraceptive pill	0.4	0.4	3.8	0.2	-0.6	-1.0	-0.7	-0.4	-0.1	1.9	-0.7	-1.1	-0.5	-1.1	-0.1	-0.5	-0.7	-0.2	-0.4	0.3	-0.3	0.6	-0.2	-0.0	-0.3	-0.3	-0.3	-0.7	-0.1
Leg fat mass (left)	0.4	1.7	3.2	-0.5	-1.3	-1.6	-1.8	-1.5	-1.2	-0.6	-1.3	-0.7	-1.4	-1.4	-0.3	-1.7	-0.2	-1.2	-1.6	-0.9	-1.5	-1.6	-0.9	-0.7	-1.2	-1.5	-1.7	-1.6	-1.6
Crohns Disease (2012)	0.3	0.6	2.0	0.3	-0.6	-1.4	-0.8	-0.7	-0.3	-0.2	-1.2	-0.1	-0.8	-0.7	0.2	-1.0	-0.7	-0.1	-0.8	-0.5	-0.8	-1.0	-0.8	-0.8	-0.8	-0.5	-0.6	-1.0	-0.8
Ulcerative Colitis	0.3	0.5	2.5	-0.7	-0.3	0.2	0.0	-0.3	-0.4	-1.6	0.1	-0.6	0.2	0.1	-1.3	-0.1	-1.4	0.2	-0.6	-1.1	-0.5	0.2	-0.6	-0.9	-0.3	-0.4	-0.6	-0.5	-0.6
Waist Hip Ratio (WHR)	0.3	1.1	4.7	-1.0	-0.9	1.1	0.5	0.9	1.0	1.6	0.7	-0.6	-1.0	-0.7	0.2	0.0	-0.3	-1.5	1.3	2.2	0.7	1.1	1.3	1.8	0.7	0.8	0.9	0.6	1.5
Hypothyroidism (self reported)	0.3	0.6	3.0	-1.3	-0.7	1.1	0.7	0.6	0.2	0.8	1.0	0.3	0.2	0.2	0.0	1.2	0.1	-1.7	0.4	1.1	0.3	0.2	0.8	1.0	0.5	0.4	0.5	0.8	1.0
Respiratory disease	0.3	0.7	4.0	1.3	1.1	0.7	0.5	0.2	0.9	0.8	0.6	0.8	1.0	0.7	2.0	0.1	-0.3	0.6	1.4	1.1	0.1	0.6	0.8	0.7	0.3	0.7	0.5	0.7	1.2
Chronotype (morning person)	0.3	0.8	4.5	1.2	1.6	0.2	0.6	0.3	0.8	0.1	0.1	1.1	1.2	1.2	2.1	0.2	0.6	2.1	0.7	-0.2	0.5	0.3	-0.0	-0.3	0.2	0.6	0.6	0.3	0.4
Severe depression (siblings)	0.3	0.4	2.0	1.4	1.3	0.0	0.1	0.4	0.5	-0.1	0.2	0.9	0.3	0.0	1.4	0.1	0.5	0.6	0.4	0.1	0.2	-0.3	0.7	-0.0	0.7	0.4	0.3	0.3	0.1
Hearing difficulty/problems with background noise	0.3	0.5	2.9	0.1	-0.5	0.7	0.6	0.4	0.7	0.9	0.4	-0.7	0.6	0.2	0.1	0.9	-0.1	0.7	1.2	0.4	0.5	1.7	0.2	0.8	-0.0	0.7	0.7	0.3	0.9
Heart attack	0.3	0.4	1.7	-0.7	-0.1	0.2	0.3	0.6	0.5	0.1	0.6	0.5	0.1	0.2	0.1	1.0	1.2	-1.1	0.4	1.3	0.4	0.1	0.8	1.0	0.4	0.4	0.3	0.5	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.7	-1.2	-0.9	-0.7	-0.4	-0.2	-0.4	-0.4	-0.3	-1.3	-1.0	-0.6	-0.9	-0.3	-0.9	-0.7	-1.0	-0.6	-0.2	0.1	-0.1	0.2	-0.6	-0.4	-0.3	-0.6	-0.4
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	4.4	-0.9	0.1	0.8	0.9	0.8	0.9	0.2	0.8	0.4	1.1	1.7	-1.2	2.1	1.7	0.9	1.6	-0.1	0.8	0.8	0.5	0.3	0.9	0.9	0.9	0.9	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.5	-0.5	-0.4	0.2	0.2	0.4	0.1	-0.2	0.7	-0.3	-0.5	-0.3	-1.0	0.1	-0.6	-1.1	-0.6	0.9	0.4	0.2	1.0	1.6	0.1	0.2	0.1	0.4	0.5
Medication: Lansoprazole	0.3	0.4	1.1	-0.3	-0.6	-0.8	-0.8	-0.8	-0.4	0.8	-0.9	-0.2	-1.0	-0.5	-0.3	-0.5	0.6	-0.9	-0.1	0.4	-0.6	-0.7	-0.6	0.1	-0.7	-0.6	-0.6	-0.6	-0.1
Pulse wave Arterial Stiffness index	0.3	0.3	1.5	0.7	0.4	-0.0	-0.4	-0.8	-0.7	0.1	-0.0	-1.2	-0.1	-0.4	0.4	-1.2	-0.8	-0.4	-0.2	-0.5	-0.7	0.0	-0.2	-0.3	-0.5	-0.7	-0.9	-0.4	-0.6
Arm fat mass (right)	0.3	1.2	2.2	-0.9	-1.4	-1.4	-1.5	-1.3	-0.9	0.1	-1.2	-0.7	-1.4	-1.3	-0.3	-1.3	-0.2	-1.4	-1.1	-0.1	-1.2	-1.2	-0.8	-0.1	-1.2	-1.2	-1.3	-1.3	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.4	0.2	-0.1	0.9	0.7	0.2	0.6	0.9	0.6	0.1	0.4	0.6	0.7	0.1	1.1	-0.1	1.5	1.0	0.4	1.0	0.4	1.4	-0.2	0.6	0.5	0.6	0.9
Leg fat percentage (right)	0.3	0.9	2.2	0.7	-0.4	-1.3	-1.4	-1.1	-0.9	-0.7	-1.1	-0.1	-0.7	-0.7	0.5	-1.1	-0.3	0.1	-1.5	-1.1	-1.0	-1.1	-0.7	-0.9	-0.9	-1.0	-1.2	-1.0	-1.4
Health satisfaction	0.3	0.4	2.0	-0.5	0.1	-0.2	0.0	0.1	-0.2	0.0	0.1	0.9	-0.6	-0.4	0.8	-0.3	1.4	-1.4	0.4	1.0	0.0	-1.1	0.1	0.8	0.1	-0.1	0.0	0.1	0.0
Emphysema/chronic bronchitis	0.3	0.4	1.3	0.1	0.6	-0.8	-0.6	-0.6	-0.3	0.3	-0.7	0.8	-0.1	0.3	0.7	-0.8	1.0	0.5	-0.3	-0.3	-0.6	-1.1	-0.6	-0.8	-0.1	-0.4	-0.5	-0.4	-0.5
Alcohol intake frequency.	0.3	0.8	5.0	0.5	-0.2	-0.3	-0.1	-0.1	-0.1	0.8	0.3	-1.7	-0.4	-1.5	1.4	-2.2	-1.7	-0.6	-0.3	0.4	-0.1	0.2	0.6	0.6	-0.9	-0.1	-0.2	-0.9	-0.5
Had major operations	0.3	0.3	2.7	-0.4	-0.0	0.1	0.4	0.2	0.7	1.6	0.2	-0.3	0.7	0.8	-0.0	0.2	1.0	0.0	0.7	0.6	0.5	0.5	0.3	0.7	0.2	0.4	0.4	0.1	0.5
Medication: Aspirin	0.3	0.4	2.1	0.7	-0.2	-1.0	-1.0	-0.7	0.0	0.0	-1.5	0.0	-0.8	-0.0	0.4	-1.0	-0.5	0.5	0.1	0.1	-0.4	-0.3	-0.8	-0.2	-0.9	-0.3	-0.3	-0.8	-0.5
Mood swings	0.3	0.5	1.4	-0.2	0.5	1.0	0.9	0.4	0.1	0.9	1.0	1.0	1.0	1.2	-1.2	1.1	1.2	0.0	0.6	0.2	0.4	0.3	0.2	0.4	0.4	0.2	0.4	0.9	0.6
Long-standing illness, disability or infirmity	0.3	0.4	1.2	0.7	0.5	-0.1	0.2	0.5	1.1	0.6	0.1	0.6	0.1	0.6	1.1	0.2	1.1	0.8	0.5	0.7	0.5	0.4	0.9	0.5	0.7	0.8	0.6	0.2	0.6
Ever had bowel cancer screening	0.3	0.3	1.3	-0.3	-0.9	-0.2	-0.0	0.1	0.7	1.0	-0.3	-0.9	-0.3	-0.2	-0.2	0.1	-1.0	0.3	0.3	0.9	0.3	1.2	0.2	0.2	0.0	0.4	0.3	-0.1	0.6
Diabetes diagnosed by doctor	0.3	0.5	1.7	0.5	0.1	1.3	0.6	0.7	0.4	0.3	1.0	-0.0	0.6	0.5	-0.0	0.2	0.7	-0.3	0.5	1.1	0.7	0.9	1.2	1.3	0.7	0.5	0.5	1.0	0.9
Commuting to job workplace: Walk	0.3	0.3	1.2	0.9	0.6	0.5	0.1	0.1	-0.1	0.4	0.6	0.4	0.1	-1.0	1.1	-0.7	0.2	-1.0	-0.3	1.0	-0.1	-0.3	0.5	0.8	0.1	0.1	-0.2	0.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.4	-0.2	-0.4	0.4	0.5	0.3	0.6	1.0	1.0	-0.5	0.4	-0.2	-0.0	-0.1	0.3	-0.9	0.3	1.1	0.4	0.9	0.8	1.2	0.7	0.4	0.3	0.3	0.5
Back pain experienced in last month	0.3	0.4	2.5	-0.8	-0.5	-0.5	-0.4	0.1	-0.4	0.2	0.2	-0.5	-1.0	-0.9	-0.7	-0.1	-0.0	-1.6	-1.0	0.3	-0.1	-1.2	0.5	0.3	0.2	-0.5	-0.3	-0.1	-0.3
Miserableness	0.3	0.5	1.6	0.1	-0.1	1.2	0.7	0.4	0.1	0.6	0.9	0.1	0.3	0.5	-1.1	0.9	-0.0	-0.6	0.7	0.8	0.4	1.2	0.7	1.0	0.4	0.3	0.4	1.2	1.2
Medication: Paracetamol	0.3	0.5	2.6	-0.2	-0.4	-0.2	0.3	0.9	0.9	1.3	0.3	-0.1	-0.4	-0.2	0.1	0.6	-0.4	0.2	0.1	1.1	0.9	1.0	1.2	1.6	0.4	0.9	0.8	0.6	0.8
Illnesses of father: High blood pressure	0.3	0.4	1.7	-0.2	-0.7	-0.2	0.2	-0.1	0.2	-0.2	-0.3	-0.0	0.4	0.8	-1.1	1.3	-0.9	1.3	0.4	-1.0	0.2	1.1	-0.6	-0.7	-0.3	0.2	0.3	0.1	0.3
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.9	-0.6	-0.4	-0.8	-0.6	-0.7	-0.5	-0.4	-0.8	-1.0	-0.4	-0.3	0.1	-0.7	-0.8	-0.2	-0.5	-0.6	-0.6	-0.4	-0.8	-0.8	-0.5	-0.7	-0.6	-0.6	-0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.3	-0.7	-0.1	0.1	0.3	0.4	0.5	0.1	0.5	0.5	0.1	0.3	-0.1	1.0	1.1	-1.0	0.5	1.1	0.4	0.0	0.7	0.9	0.3	0.4	0.3	0.5	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.6	-1.2	-0.4	-1.1	-0.4	0.2	0.2	0.2	-0.2	-0.6	-1.0	-0.9	-0.3	-0.4	-1.4	-0.8	-1.6	0.2	-0.0	-1.0	0.4	0.2	-0.4	-0.1	-0.2	-0.9	-0.5
Alzheimer’s Disease (including proxy)	0.2	0.3	1.4	0.1	0.2	0.3	0.5	-0.2	0.2	0.8	-0.0	0.4	1.0	0.7	0.0	-0.4	1.2	0.5	1.2	0.1	0.0	-0.0	-0.6	-0.1	-0.0	0.5	0.1	-0.1	0.2
Crohns Disease (2017)	0.2	0.4	2.8	1.2	0.6	-0.8	-0.0	0.4	0.8	-0.5	-0.5	0.6	0.1	0.5	0.5	0.6	0.4	1.7	0.3	-0.6	0.4	0.2	0.1	-0.6	0.5	0.6	0.6	0.1	0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	4.4	-0.6	0.2	-0.7	-0.1	0.5	0.3	-0.5	0.2	-0.2	-0.4	-0.6	-0.3	-0.2	-2.1	-0.4	-1.5	-0.0	0.3	-0.9	0.6	0.2	0.2	0.1	0.1	-0.5	-0.5
Breast Cancer	0.2	0.4	2.5	-0.2	0.1	-0.5	-0.5	-0.7	-0.6	0.1	-0.5	1.1	-0.5	-0.4	-1.3	-0.1	0.2	-0.8	-0.5	0.4	-0.7	-1.6	-0.7	0.1	-0.5	-0.7	-0.6	0.0	-0.2
Neuroticism (2016)	0.2	0.3	2.2	-0.7	-0.8	-0.0	0.3	0.7	-0.1	1.5	-0.2	0.1	-0.4	0.1	0.2	0.0	-0.1	-0.1	0.5	0.5	0.6	0.7	-0.1	0.2	-0.1	0.2	0.9	0.3	1.0
Primary Biliary Cirrhosis	0.2	0.3	1.1	0.0	-0.3	-0.6	-0.6	-0.4	-0.4	-0.1	-0.6	-0.4	-0.7	-0.4	-0.6	-0.7	-0.8	-0.6	-1.1	-0.4	-0.5	-0.5	-0.4	-0.0	-1.0	-0.4	-0.5	-0.7	-0.7
Rheumatoid Arthritis	0.2	0.2	1.5	-1.1	-0.7	-0.1	0.0	-0.2	0.4	-0.5	-0.4	0.1	-0.4	0.4	-0.6	0.4	-1.2	0.4	0.4	-0.0	-0.2	0.7	-0.6	-0.4	-0.1	0.3	0.1	-0.3	0.3
BMI	0.2	1.4	3.1	-0.1	-0.3	-1.4	-1.4	-1.2	-1.0	-0.5	-1.3	-0.4	-0.6	-0.7	0.6	-1.6	-0.6	0.3	-1.6	-1.5	-1.3	-1.5	-1.0	-1.4	-1.4	-1.2	-1.4	-1.6	-1.8
Height	0.2	3.3	12.6	-0.9	-0.4	2.1	1.7	2.0	1.7	0.5	2.5	-0.0	0.4	0.0	0.1	1.4	0.2	-2.3	1.6	3.5	1.7	1.4	2.7	3.1	2.4	1.6	1.6	1.9	2.5
Neuroticism	0.2	0.6	1.4	-0.3	0.0	1.2	1.0	0.8	0.5	0.1	1.1	0.8	0.3	0.7	-0.8	0.8	0.3	-0.6	0.5	0.9	0.8	0.7	0.7	1.1	1.0	0.7	0.8	0.8	0.9
Hand grip strength (left)	0.2	0.6	3.5	-0.4	0.1	0.8	0.7	0.9	0.7	-1.9	1.2	-0.2	0.2	-0.3	1.4	0.2	0.1	-0.7	0.4	0.9	0.6	0.4	1.2	0.5	1.2	0.5	0.5	0.5	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	2.0	0.7	-0.2	-0.3	-0.4	-0.6	-0.4	-1.4	-0.2	-0.7	-0.1	-0.4	0.6	0.3	-1.1	-0.1	-0.1	0.2	-0.5	0.4	-0.1	0.2	-0.9	-0.3	-0.4	0.1	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	0.7	-0.2	-0.2	-0.3	-0.4	-0.3	-0.3	-0.2	-0.8	0.5	-0.0	0.8	-0.8	-0.0	0.7	0.1	-1.0	-0.0	0.6	-0.1	-0.1	-0.7	-0.3	-0.3	-0.4	-0.5
Hand grip strength (right)	0.2	0.6	2.9	-0.4	-0.4	0.7	0.7	0.9	0.9	-1.7	1.1	-0.7	-0.0	-0.5	1.1	0.0	-0.4	-1.0	0.5	1.3	0.6	0.6	1.2	0.9	0.9	0.7	0.6	0.3	0.7
Average weekly fortified wine intake	0.2	0.2	1.6	-0.6	0.4	0.5	0.2	0.2	0.3	0.7	0.1	1.3	0.1	0.5	-0.5	0.4	0.7	-0.0	0.4	0.6	0.1	-0.1	-0.2	0.1	0.6	0.2	0.3	0.5	0.6
Fed-up feelings	0.2	0.3	1.4	0.1	-0.2	0.3	0.3	0.5	0.5	0.2	0.1	0.2	-0.1	0.9	-1.2	1.0	0.5	0.6	0.4	-0.0	0.6	1.0	0.3	0.5	0.6	0.5	0.6	0.8	0.9
Relative age voice broke	0.2	0.4	1.8	0.1	0.1	-0.7	-0.4	-0.5	-0.2	1.3	-0.7	1.0	-0.4	-0.3	-0.4	-0.3	1.3	-0.1	-1.0	-0.2	-0.4	-0.5	-0.9	-0.3	-0.3	-0.1	-0.2	-0.5	-0.5
Qualifications: CSEs or equivalent	0.2	0.3	1.7	0.4	0.5	-0.2	0.5	0.6	0.2	-1.0	0.6	1.3	0.7	0.5	-0.1	0.5	0.9	0.8	-0.2	-0.6	0.5	-0.0	0.4	-0.1	0.3	0.3	0.4	0.1	-0.2
Serious illness, injury or assault to yourself	0.2	0.3	3.9	-0.8	-0.8	-0.3	-0.1	0.0	0.3	0.6	-0.2	-0.4	-0.3	0.3	-2.0	0.2	0.8	-0.1	0.2	-0.0	0.2	0.2	-0.2	0.6	-0.5	0.2	0.1	-0.3	-0.0
Stomach or abdominal pain in last month	0.2	0.3	1.5	0.4	0.0	-0.6	0.3	0.7	0.6	-0.7	0.4	-0.3	-0.4	-0.6	-0.4	-0.1	-1.2	0.3	-0.3	0.0	0.7	0.6	0.7	0.5	0.4	0.4	0.6	-0.1	-0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.9	0.0	-0.8	-0.1	0.1	-0.1	0.5	0.1	-0.6	-0.6	-0.0	0.6	0.4	0.6	-0.9	0.6	1.0	0.1	0.1	1.4	-0.3	0.2	-0.0	0.5	0.4	0.1	0.8
Medication: Levothyroxine sodium	0.2	0.3	1.1	-0.7	-1.0	0.3	-0.1	0.2	0.2	0.3	0.1	-0.8	-0.5	-0.5	0.7	0.5	-0.7	-1.0	-0.2	0.8	0.1	0.7	0.7	0.9	-0.2	0.3	0.2	0.2	0.6
High blood pressure (mother)	0.2	0.3	1.3	-0.4	-0.2	-1.1	-0.6	-0.2	-0.4	-0.6	-0.7	-0.0	-0.3	-0.2	0.0	0.2	-0.3	0.5	-1.0	-0.8	-0.2	-1.1	-0.3	-1.1	-0.4	-0.6	-0.4	-0.5	-0.6
Waist circumference	0.2	0.8	1.9	-0.3	-1.0	-1.3	-1.3	-1.0	-0.5	0.1	-0.9	-1.0	-1.1	-1.3	0.4	-1.4	-0.8	-0.8	-0.7	-0.2	-1.0	-0.7	-0.3	-0.0	-1.1	-0.8	-1.0	-1.2	-0.9
Past tobacco smoking	0.2	0.4	2.7	-0.9	-1.3	-0.6	-0.0	-0.2	0.3	0.5	-0.3	-1.0	-0.2	-0.4	0.2	-0.1	-1.7	-0.4	0.9	0.5	-0.1	0.9	-0.4	0.6	-0.7	0.1	0.1	-0.7	0.3
Alcohol usually taken with meals	0.2	0.4	1.9	-0.4	-0.3	0.4	0.6	0.6	0.7	-0.3	0.5	-0.1	0.3	-0.1	0.8	0.4	0.5	-0.3	0.9	1.4	0.6	0.3	0.6	1.1	0.0	0.6	0.6	0.4	0.9
Had menopause	0.2	0.2	0.7	-0.0	0.0	-0.4	-0.6	-0.4	-0.7	-0.6	-0.3	-0.6	-0.4	-0.7	0.1	-0.9	-0.3	-0.2	-0.7	-0.4	-0.5	-0.1	-0.2	-0.6	-0.1	-0.5	-0.6	-0.5	-0.7
Had other major operations	0.2	0.2	1.6	0.5	0.0	0.0	0.1	-0.3	0.5	0.9	-0.2	0.3	0.2	0.3	1.3	-0.2	0.4	0.4	1.1	0.7	-0.1	0.4	-0.2	0.3	-0.2	0.3	0.1	0.0	0.6
Allergy	0.2	0.5	2.4	-0.8	-0.7	-0.2	-0.7	0.1	-0.6	-0.6	-0.5	-0.8	-1.1	-0.5	-1.6	-0.9	0.1	-0.5	-1.0	-0.3	-0.1	-1.1	-0.2	-0.3	-0.2	-0.4	-0.4	-0.5	-0.9
Pain all over the body in last month	0.2	0.2	0.9	-0.5	-0.8	0.4	0.2	-0.2	-0.6	0.1	0.4	-0.9	0.2	-0.2	-0.6	0.9	-0.5	-0.5	0.2	-0.4	-0.1	0.6	0.0	0.4	-0.6	-0.2	-0.2	0.3	-0.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.0	0.5	0.7	-0.1	0.2	0.2	-0.0	1.0	0.4	0.3	1.0	0.3	0.2	0.5	0.7	1.0	-0.3	-0.8	0.2	0.2	0.2	-0.8	0.6	-0.1	0.0	-0.1	-0.5
Falls in the last year	0.2	0.3	2.2	-1.0	-0.8	0.3	-0.2	-0.2	-0.1	1.5	0.1	-0.7	0.0	-0.3	-0.8	-0.2	-0.3	-1.2	-0.3	0.5	-0.2	-0.1	0.4	0.9	-0.4	-0.2	-0.3	-0.0	0.3
Asthma	0.2	0.4	2.4	0.8	0.1	0.4	0.3	0.2	0.6	0.1	0.6	-0.1	0.3	-0.2	1.6	0.1	-1.1	-0.5	1.0	1.1	0.0	0.6	1.0	0.9	0.2	0.4	0.3	0.5	1.1
Pulse wave reflection index	0.2	0.3	1.5	0.8	0.4	0.8	0.3	0.1	-0.1	1.2	1.0	-0.9	0.5	-0.3	-0.1	-0.5	-0.2	-0.2	-0.2	0.3	0.0	0.6	0.7	0.3	0.4	0.0	-0.2	0.2	-0.3
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.2	-0.0	0.2	-0.4	0.1	0.4	0.3	-0.5	-0.1	1.1	0.2	0.4	0.2	1.0	-0.6	0.5	-0.2	0.0	0.5	0.1	0.2	0.0	0.4	0.3	0.5	0.2	0.3
Glaucoma (self-reported)	0.2	0.2	1.4	0.5	-0.7	-0.5	-0.5	-0.3	-0.3	-0.6	-0.4	-1.2	-0.7	-0.8	-0.2	-0.4	-0.6	-0.2	-0.6	-0.1	-0.3	0.7	0.1	-0.1	-0.3	-0.4	-0.2	-0.3	-0.0
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.2	-1.0	-1.1	0.7	0.2	0.5	0.2	0.2	0.5	-0.5	-0.3	-0.3	0.3	0.6	-0.7	-1.5	-0.3	1.0	0.2	0.4	0.9	0.9	0.4	0.3	0.3	0.4	0.7
Medication: Amlodipine	0.2	0.3	2.5	0.8	0.5	0.2	0.2	0.5	0.6	-0.0	-0.0	1.0	0.7	0.9	0.7	-0.1	0.4	1.6	0.2	-0.5	0.7	0.2	0.4	0.3	0.3	0.5	0.5	0.4	0.1
Exposure to tobacco smoke outside home	0.2	0.3	1.2	0.6	-0.3	-0.7	-0.7	-0.5	-0.2	0.3	-0.9	-0.3	-0.6	-0.5	1.1	-0.7	-0.5	0.0	-0.4	-0.1	-0.5	-0.3	-0.3	0.1	-1.0	-0.3	-0.3	-0.3	-0.1
Wheeze or whistling in the chest in last year	0.2	0.4	1.7	-0.4	-1.1	-0.9	-0.3	-0.3	0.2	0.9	-0.6	-1.3	-0.6	-0.7	-0.2	-0.6	-0.9	-0.3	0.5	0.4	-0.1	0.7	-0.1	0.4	-0.5	-0.1	-0.1	-0.5	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.4	0.2	0.7	0.6	0.6	-0.1	0.2	-0.3	0.3	0.7	1.1	1.0	-0.2	0.0	0.2	0.8	1.2	-0.1	0.2	0.5	-0.3	0.1	-0.0	0.3	0.2	0.4	0.4
Pulse wave peak to peak time	0.2	0.3	1.1	-0.8	-0.5	0.0	0.3	0.6	0.5	-0.3	-0.1	1.0	0.0	0.3	-0.5	1.0	0.9	0.2	0.3	0.4	0.5	-0.1	-0.0	0.2	0.5	0.5	0.7	0.3	0.5
Qualifications: College or University degree	0.2	0.8	4.0	-1.7	0.3	0.6	1.1	0.9	0.7	0.3	0.9	0.6	0.6	1.1	-2.0	1.7	0.2	0.0	0.8	0.1	0.9	0.2	0.3	0.5	0.8	0.8	0.9	0.7	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	2.4	-0.3	0.5	0.1	0.3	0.0	-0.4	-0.2	0.3	-0.0	0.8	0.2	0.2	0.1	1.3	0.4	-0.2	-1.3	-0.1	-0.8	-0.4	-1.5	0.5	-0.3	-0.2	-0.3	-0.6
Chest pain or discomfort	0.2	0.3	1.6	0.7	0.8	-0.6	-0.4	-0.3	-0.3	0.2	-0.1	0.3	0.0	-0.4	0.6	-1.3	0.9	0.3	-0.4	-0.1	-0.3	-1.2	-0.1	-0.3	-0.3	-0.5	-0.4	-0.6	-0.7
Family relationship satisfaction	0.2	0.3	1.7	0.5	0.8	0.2	0.1	0.4	-0.0	0.7	0.3	0.8	-0.6	-0.6	1.3	0.2	-0.6	-0.4	-0.5	0.5	0.2	-0.2	0.5	0.1	0.5	0.3	0.3	0.1	-0.1
Leg pain on walking	0.2	0.3	1.5	0.7	0.1	0.9	0.5	0.3	0.2	0.3	0.5	-0.4	0.2	-0.1	1.2	-0.0	-0.6	0.2	0.7	0.1	0.4	1.2	0.5	0.7	-0.3	0.4	0.3	0.3	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.4	-0.1	-1.0	-0.0	-0.0	-0.0	0.2	0.1	-0.2	-0.9	-0.1	-0.1	-0.4	-0.1	-0.1	-0.3	0.6	0.3	0.3	1.2	-0.0	0.9	-0.1	0.2	0.1	-0.1	0.2
Illnesses of father: Heart disease	0.2	0.2	0.8	-0.3	-0.2	-0.9	-0.4	-0.4	-0.3	0.8	-0.3	-0.1	-0.1	-0.3	-0.6	-0.5	0.2	-0.3	-0.6	-0.4	-0.5	-0.8	-0.3	-0.4	-0.3	-0.5	-0.4	-0.6	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	7.0	-0.6	-0.2	-0.4	-0.4	-0.2	-0.5	-2.7	-0.1	-0.3	-0.6	-0.1	-0.9	0.1	-0.6	-0.4	-0.5	-0.7	-0.3	-0.8	-0.0	-0.5	0.1	-0.5	-0.5	-0.2	-0.4
Average weekly red wine intake	0.2	0.3	1.2	-0.9	-0.8	0.0	0.1	0.3	0.2	-1.0	0.1	-1.1	-0.3	-0.7	-0.6	0.8	-0.9	-0.1	0.0	0.1	0.2	0.9	0.2	-0.0	0.1	0.0	0.2	0.1	0.3
Eye problems/disorders: Cataract	0.2	0.2	1.7	0.8	0.7	0.0	0.4	0.2	0.2	0.5	0.1	0.2	0.6	0.3	0.1	-0.6	1.3	0.8	0.4	-0.1	0.4	0.1	-0.1	-0.1	0.4	0.3	0.4	0.2	0.1
Asthma (self-reported)	0.2	0.4	2.6	0.8	0.1	0.2	0.1	-0.1	0.5	-0.1	0.2	-0.1	0.1	-0.2	1.6	-0.1	-1.5	-0.3	0.9	1.0	-0.2	0.6	0.7	0.6	-0.1	0.2	0.1	0.3	0.9
Number of self-reported non-cancer illnesses	0.2	0.3	1.4	0.6	-0.6	-0.5	-0.6	-0.5	0.5	-0.1	-0.7	-0.8	-0.7	-0.6	1.2	-0.8	-0.9	-0.0	0.8	0.6	-0.3	0.4	0.2	0.2	-0.1	0.1	-0.2	-0.4	0.4
Leg fat percentage (left)	0.2	0.8	1.8	0.7	-0.4	-1.4	-1.3	-1.1	-0.7	-0.5	-1.1	-0.1	-0.7	-0.7	0.4	-1.1	-0.2	0.1	-1.3	-1.0	-1.0	-0.9	-0.7	-0.7	-1.0	-0.9	-1.1	-1.1	-1.3
Ever depressed for a whole week	0.2	0.2	1.2	0.0	-0.7	-0.0	-0.1	-0.1	-0.2	-0.6	-0.0	-0.8	-0.6	-0.4	0.1	-0.3	-0.9	-0.7	0.3	0.3	0.1	0.6	0.1	1.1	-0.5	-0.1	-0.1	0.0	0.1
Commuting to job workplace: Cycle	0.2	0.3	1.3	-0.3	-0.2	-1.1	-0.6	-0.6	-0.4	0.3	-1.0	-0.2	-0.3	-0.5	0.3	0.5	-0.9	0.2	-0.2	-0.4	-0.4	0.1	-0.6	-0.7	-0.7	-0.3	-0.2	-0.5	-0.1
Pain experienced in last month	0.2	0.3	1.0	0.5	0.6	-0.0	-0.3	-0.6	0.2	-0.8	-0.7	0.8	-0.0	0.3	0.9	-0.4	-0.2	0.9	0.6	-0.2	-0.4	-0.0	-0.8	-1.0	0.1	-0.0	-0.2	-0.3	-0.0
Pack years of smoking	0.2	0.3	1.6	0.2	0.6	-0.5	-0.6	-0.6	-0.4	-0.2	-0.6	0.6	-0.3	-0.0	0.4	-1.3	0.2	-0.4	-0.5	-0.1	-0.5	-0.9	-0.4	-0.4	-0.2	-0.6	-0.6	-0.3	-0.3
Neuroticism (Nagel 2018)	0.1	0.4	1.6	-0.2	-0.9	0.6	0.3	0.2	-0.0	1.2	0.4	0.2	-0.0	0.0	-0.9	1.1	0.2	-1.0	0.7	0.6	0.2	0.8	0.1	0.7	0.4	0.1	0.2	0.5	0.7
Schizophrenia vs Biploar Disorder	0.1	0.2	0.9	0.5	0.5	0.1	-0.1	0.2	-0.2	-0.3	0.3	-0.1	0.0	-0.4	0.3	-0.9	0.2	0.6	-0.9	-0.7	0.2	-0.6	0.2	-0.4	0.3	-0.0	-0.1	-0.2	-0.9
Worry (Nagel 2018)	0.1	0.3	2.4	-1.1	-1.0	0.3	0.1	-0.1	-0.5	-0.1	0.3	0.1	-0.5	-0.4	-1.3	0.1	0.3	-1.6	-0.0	0.4	-0.2	0.0	-0.3	0.2	0.4	-0.2	-0.2	-0.1	-0.0
Irritable Bowel Disease (IBD)	0.1	0.2	1.4	0.4	-0.1	-0.6	-0.3	-0.1	0.1	-1.2	-0.4	-0.2	-0.3	-0.2	-0.8	-0.3	-0.7	0.7	-0.3	-0.6	-0.2	-0.0	-0.4	-0.7	-0.1	-0.0	-0.2	-0.6	-0.5
Body Mass Index (BMI) (2010)	0.1	0.1	0.9	-0.1	0.1	0.2	-0.0	-0.0	-0.3	0.1	0.3	0.4	-0.2	-0.3	0.1	-0.4	0.0	-0.5	-1.0	0.0	-0.2	-0.5	0.0	-0.3	0.4	-0.3	-0.1	-0.2	-0.4
Coronary Artery Disease (CAD)	0.1	0.1	0.7	0.0	-0.2	-0.4	0.3	0.3	0.2	-0.6	0.4	-0.6	-0.3	-0.4	0.2	-0.1	-0.6	-0.5	0.3	0.8	0.2	-0.1	0.4	0.2	0.3	-0.0	0.2	-0.1	0.2
Blood Eosinophil Count	0.1	0.5	1.3	0.3	1.1	0.7	0.1	-1.0	-0.8	0.5	0.1	1.0	0.4	0.3	1.0	-0.6	0.9	-0.5	0.7	-0.3	-1.1	-0.6	-1.1	-0.9	-0.3	-0.7	-0.7	-0.2	-0.1
Blood Red Count	0.1	0.7	9.0	0.8	-0.1	-0.0	0.3	0.2	0.3	-1.0	0.7	-1.8	-0.2	-0.6	-0.3	-1.4	-3.0	0.1	-0.1	0.1	0.1	0.4	0.6	0.2	-0.3	-0.0	-0.0	-0.7	-0.3
Blood White Count	0.1	0.5	3.9	-0.0	-0.2	0.6	-0.4	-1.0	-0.7	-2.0	-0.4	-0.2	-0.2	0.4	-0.7	-0.5	-1.0	0.1	0.2	-0.8	-0.9	0.6	-1.0	-0.6	-0.9	-0.6	-0.7	-0.2	-0.3
Heel T-Score	0.1	0.6	3.3	0.6	0.0	-0.6	-0.4	-0.6	-1.2	-0.9	-0.1	-0.8	0.0	-0.9	0.0	-0.7	-1.8	-0.1	-1.1	-0.6	-0.6	-0.4	-0.2	-0.1	-1.0	-0.9	-0.8	-0.3	-0.8
Cardiovascular Disease	0.1	0.4	1.3	0.1	-0.4	0.0	0.2	0.5	1.0	-0.1	0.1	0.4	0.2	0.2	1.1	0.3	-0.0	0.4	0.9	1.1	0.7	0.8	0.8	1.1	0.2	0.8	0.6	0.4	0.8
Lung FVC	0.1	0.4	1.3	-0.7	-0.8	-0.5	-0.8	-0.3	-0.5	0.3	-0.4	-0.9	-0.4	-0.4	-1.1	-0.4	-0.1	-0.6	-0.9	-0.4	-0.4	-1.1	-0.0	-0.2	-0.4	-0.6	-0.7	-0.6	-0.7
Medication: Metformin	0.1	0.1	1.1	0.8	0.2	0.5	0.0	0.0	-0.1	-0.0	0.3	-0.5	0.3	-0.1	0.2	-1.1	0.1	0.1	-0.0	0.1	0.1	0.2	0.5	0.3	-0.0	0.0	-0.1	0.1	-0.1
Trunk fat percentage	0.1	0.4	2.0	0.0	-0.1	0.3	0.3	0.3	0.8	1.2	0.3	0.8	0.1	0.3	0.2	0.1	0.8	-0.2	0.7	1.3	0.5	0.7	0.4	1.4	0.3	0.7	0.5	0.3	0.6
Age when periods started (menarche)	0.1	0.3	1.8	0.1	0.3	-0.7	-0.3	0.2	0.4	0.6	-0.7	1.3	-0.6	-0.4	-0.2	0.4	1.2	-0.2	-0.3	0.9	0.1	-0.9	-0.0	-0.1	0.5	0.1	0.2	-0.1	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.5	0.4	-0.5	-0.1	-0.0	-0.0	0.3	-0.3	-0.5	-1.1	0.5	0.8	-0.5	0.9	-0.6	1.2	0.3	-0.7	0.3	1.0	-0.1	-0.0	-0.4	0.2	0.3	0.4	0.5
High blood pressure	0.1	0.2	1.5	-0.3	-1.2	-0.5	-0.5	-0.2	0.3	-0.0	-0.6	-0.5	-0.5	-0.5	0.2	-0.7	-0.8	-0.5	0.4	0.8	-0.0	0.1	0.1	0.7	-0.3	-0.0	-0.2	-0.3	0.2
Forced vital capacity (FVC)	0.1	0.5	3.3	-1.8	-0.8	0.2	0.2	0.6	0.4	-0.1	0.5	-0.6	-0.3	0.2	-1.7	1.1	0.9	-0.8	0.4	0.5	0.3	-0.5	0.7	0.3	0.9	0.2	0.2	0.2	0.5
Neuroticism score	0.1	0.2	1.1	-0.7	-0.4	0.8	0.6	0.2	0.0	0.3	0.6	0.1	-0.0	0.3	-1.0	0.9	0.1	-0.5	0.4	0.4	0.2	0.8	0.0	0.4	0.2	0.2	0.3	0.4	0.6
Arm fat percentage (right)	0.1	0.3	2.0	0.0	-0.7	-0.1	0.0	0.1	0.6	1.4	-0.0	0.3	-0.1	0.0	0.3	0.1	0.6	-0.2	0.7	1.0	0.4	0.6	0.3	1.3	-0.1	0.5	0.3	0.1	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	3.0	-1.2	-0.4	0.2	0.1	-0.3	-0.2	-0.7	0.1	-0.3	0.7	0.9	-1.7	1.4	0.2	0.3	0.7	-1.1	-0.2	0.1	-0.5	-0.6	-0.1	-0.2	-0.2	0.0	0.0
Standing height	0.1	0.7	2.5	-1.5	0.0	1.0	0.7	0.7	0.4	-0.6	1.4	0.2	0.0	0.0	-0.4	0.5	0.5	-1.6	0.6	1.6	0.4	-0.4	1.1	1.0	1.4	0.3	0.4	0.7	0.9
Tense / ‘highly strung’	0.1	0.2	1.0	-0.3	0.2	1.0	0.6	0.1	-0.0	0.7	0.9	0.5	0.1	0.3	-0.0	0.5	0.2	-0.8	0.4	0.8	0.1	0.6	0.2	0.2	0.6	0.1	0.2	0.4	0.5
Peak expiratory flow (PEF)	0.1	0.3	1.9	-0.5	-0.3	0.2	0.4	0.5	0.7	-0.4	0.4	-0.1	0.3	0.6	-0.3	0.8	1.4	0.2	1.0	0.2	0.6	0.5	0.5	0.6	0.4	0.7	0.5	0.3	0.5
Medication: Paracetamol	0.1	0.2	1.4	0.2	-0.2	0.1	0.2	0.4	0.4	0.5	0.3	0.0	-0.2	-0.3	0.4	-0.2	-0.3	-0.0	-0.2	1.0	0.5	0.6	0.7	1.2	0.1	0.4	0.4	0.4	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.5	0.6	-0.4	-0.4	-0.0	0.1	0.2	0.4	-0.2	-0.4	0.2	0.3	-0.0	-0.2	0.4	0.7	-0.1	-0.3	0.3	0.1	-0.0	-0.1	0.2	0.1	0.3	-0.2	-0.2
High blood pressure (siblings)	0.1	0.1	0.6	-0.2	-0.3	-0.5	-0.2	-0.0	0.3	0.3	-0.5	0.5	0.2	0.4	0.7	0.8	-0.2	0.7	0.3	-0.1	0.0	0.1	-0.0	-0.2	-0.1	0.2	0.1	-0.1	0.2
Forced vital capacity (FVC), Best measure	0.1	0.5	3.5	-1.7	-1.1	-0.2	-0.4	-0.3	-0.3	-0.6	-0.0	-0.9	-0.5	-0.3	-1.9	0.6	-0.2	-1.0	-0.1	-0.2	-0.4	-0.7	-0.2	-0.3	-0.1	-0.4	-0.5	-0.5	-0.2
Medication: Seretide 50 evohaler	0.1	0.2	1.9	-0.2	0.3	-0.2	-0.1	-0.4	0.1	-0.1	-0.0	-0.2	-0.3	-0.6	0.6	-0.1	-1.4	-0.4	0.1	0.6	-0.4	0.2	0.0	-0.2	-0.1	-0.1	-0.2	-0.4	0.1
Whole body fat mass	0.1	0.6	1.4	-0.6	-0.9	-0.9	-1.0	-0.9	-0.6	0.1	-0.6	-0.2	-0.9	-0.9	-0.4	-1.1	0.3	-1.2	-0.8	0.1	-0.8	-1.0	-0.4	0.1	-0.7	-0.8	-1.0	-0.9	-0.9
Comparative height size at age 10	0.1	0.6	4.2	-2.1	-0.8	0.4	0.1	0.3	0.5	-0.4	0.6	-0.2	-0.8	-0.1	-0.5	0.8	-0.7	-1.3	0.6	1.2	0.2	0.3	0.8	1.1	0.7	0.2	0.2	0.5	1.0
Hypertension (Self-reported)	0.1	0.2	1.0	-0.3	-1.0	-0.2	-0.3	-0.1	0.4	0.0	-0.3	-0.3	-0.4	-0.3	-0.0	-0.6	-0.5	-0.4	0.5	0.8	0.1	0.3	0.2	0.9	-0.2	0.1	-0.1	-0.1	0.3
Smoking status: Previous	0.1	0.2	1.5	0.8	0.8	0.5	-0.0	0.1	-0.2	0.2	0.2	0.4	0.3	0.2	-0.0	-0.2	1.2	0.1	-0.4	0.1	0.1	-0.6	0.3	0.1	0.1	-0.1	-0.1	0.6	0.0
Average weekly beer plus cider intake	0.1	0.2	0.8	-0.8	-0.2	-0.4	-0.2	-0.4	-0.1	0.3	-0.3	0.3	0.0	0.6	-0.6	0.0	0.5	0.2	0.6	-0.9	-0.3	-0.3	-0.6	-0.2	-0.4	-0.2	-0.3	-0.5	-0.3
Myopia	0.1	0.2	1.1	0.0	-0.9	-0.0	0.1	0.3	0.2	0.0	0.4	-0.8	-0.2	-0.7	-0.5	0.3	-0.2	-0.4	0.1	0.4	0.3	0.7	0.4	1.0	-0.6	0.1	0.2	0.1	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.9	-0.0	1.0	0.7	0.6	0.4	-0.3	-0.0	0.9	0.2	0.6	0.3	-0.2	0.8	0.8	0.2	-0.4	-0.7	0.2	0.0	0.2	-0.5	0.5	0.1	0.2	0.5	-0.1
Cholesterol lowering medication	0.1	0.2	1.3	-1.1	-0.7	0.3	0.0	0.2	0.3	-0.2	0.2	-0.6	-0.4	-0.3	-0.3	0.5	-0.9	-0.5	0.1	0.5	0.0	0.5	0.5	0.5	0.0	0.2	0.1	0.1	0.4
Blood Platelet Count	0.0	0.2	1.3	-0.8	-0.6	1.1	0.3	-0.2	-0.2	-0.1	0.6	-0.2	0.3	0.1	-0.6	-0.3	-0.5	-0.5	0.3	0.2	-0.2	0.8	0.1	0.2	-0.0	-0.2	-0.3	-0.7	-0.2
Hair Pigment	0.0	0.2	1.8	-0.3	0.1	0.7	0.5	-0.1	0.3	-0.6	-0.0	0.1	0.6	1.3	-0.1	0.7	0.5	0.7	0.5	-0.0	0.2	0.2	-0.3	-0.0	-0.5	0.2	0.3	0.4	0.4
Tanning	0.0	0.2	1.5	-0.6	-0.2	0.8	-0.1	-0.3	-0.6	-0.0	0.3	-0.3	-0.2	-0.5	-0.3	-0.3	0.4	-1.2	-0.1	0.1	-0.6	-0.4	-0.2	-0.2	-0.1	-0.4	-0.6	-0.3	-0.3
Sitting height	0.0	0.3	2.5	-1.4	0.0	0.1	0.1	0.3	-0.0	-1.6	0.5	0.2	-0.3	0.2	-0.7	0.2	0.8	-0.8	-0.5	0.2	0.0	-1.0	0.4	-0.1	0.7	-0.2	-0.1	-0.1	-0.0
Trunk fat mass	0.0	0.2	0.8	-0.5	-0.6	-0.4	-0.5	-0.4	-0.0	0.4	-0.2	0.2	-0.6	-0.5	-0.1	-0.6	0.4	-0.9	-0.2	0.6	-0.3	-0.3	-0.0	0.7	-0.2	-0.2	-0.4	-0.4	-0.2
Body fat percentage	0.0	0.1	0.9	0.2	-0.3	-0.1	-0.1	-0.0	0.4	0.9	-0.0	0.5	-0.2	-0.0	0.1	-0.2	0.6	-0.3	0.1	0.7	0.1	0.2	0.2	0.9	-0.0	0.3	0.1	-0.0	0.1
Arm fat percentage (left)	0.0	0.2	1.0	-0.1	-0.9	-0.5	-0.4	-0.3	0.2	1.0	-0.4	0.0	-0.5	-0.4	0.1	-0.4	0.2	-0.4	0.1	0.5	-0.1	0.2	-0.1	0.7	-0.5	0.0	-0.1	-0.4	-0.1