Best TWAS P=3.97e-09 · Best GWAS P=8.98e-12 conditioned to 2.84e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PTGFR | 0.12 | 0.04 | enet | 17 | 0.04 | 4.7e-04 | -4.0 | 5.8 | 8.2e-09 | -0.26 | 0.96 | 0.01 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FAM73A | 0.09 | 0.04 | enet | 19 | 0.06 | 9.6e-09 | 2.8 | -5.5 | 4.4e-08 | 0.33 | 0.98 | 0.02 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | DNAJB4 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.2e-05 | -5.9 | 5.9 | 4.0e-09 | -0.45 | 0.00 | 1.00 | TRUE |