TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of whole body
:
←
→
chr1:77,547,831-79,699,821
Best TWAS P=3.97e-09 · Best GWAS P=8.98e-12 conditioned to 2.84e-06
77.5M
78M
78.5M
79M
79.5M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Adenocarcinoma
DNAJB4
0.04
0.04
lasso
2
0.04
1.2e-05
-5.9
5.9
4.0e-09
-0.45
0.00
1.00
TRUE
1
GTEx
Cells Transformed fibroblasts
PTGFR
0.12
0.04
enet
17
0.04
4.7e-04
-4.0
5.8
8.2e-09
-0.26
0.96
0.01
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
FAM73A
0.09
0.04
enet
19
0.06
9.6e-09
2.8
-5.5
4.4e-08
0.33
0.98
0.02
FALSE