Best TWAS P=2.69e-09 · Best GWAS P=1.4e-09 conditioned to 0.048
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | EVI5 | 0.08 | 0.08 | lasso | 10 | 0.12 | 9.5e-10 | -3.6 | -5.3 | 9.7e-08 | 0.79 | 0.10 | 0.90 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FAM69A | 0.10 | 0.13 | lasso | 4 | 0.15 | 2.4e-19 | -5.8 | -5.3 | 1.0e-07 | 0.78 | 0.09 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | EVI5 | 0.14 | 0.04 | blup | 93 | 0.06 | 8.9e-03 | -5.9 | -5.7 | 1.5e-08 | 0.84 | 0.04 | 0.65 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | EVI5 | 0.08 | 0.04 | blup | 96 | 0.06 | 8.6e-08 | -3.2 | -5.2 | 1.7e-07 | 0.64 | 0.89 | 0.10 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EVI5 | 0.04 | 0.02 | blup | 96 | 0.04 | 1.4e-03 | -6.0 | -6.0 | 2.7e-09 | 0.83 | 0.04 | 0.62 | TRUE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | EVI5 | 0.05 | 0.02 | blup | 96 | 0.03 | 2.3e-03 | -2.6 | -5.3 | 1.3e-07 | 0.75 | 0.09 | 0.70 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EVI5 | 0.06 | 0.10 | blup | 94 | 0.10 | 1.7e-10 | -4.5 | -5.2 | 1.8e-07 | 0.71 | 0.97 | 0.03 | FALSE |