Best TWAS P=6.16e-08 · Best GWAS P=2.55e-07 conditioned to 0.0559
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | PTK2 | 0.28 | 0.01 | lasso | 4 | 0.09 | 1.5e-03 | -4.5 | 5.1 | 3.1e-07 | -0.59 | 0.10 | 0.52 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PTK2 | 0.05 | 0.07 | lasso | 4 | 0.07 | 5.4e-09 | -5.1 | 5.1 | 3.1e-07 | -0.98 | 0.04 | 0.96 | FALSE |
| 3 | YFS | Blood | PTK2 | 0.02 | 0.00 | blup | 538 | 0.01 | 8.6e-04 | -4.9 | 5.4 | 6.2e-08 | -0.70 | 0.05 | 0.53 | TRUE |