TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of whole body
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chr8:140,969,818-142,706,843
Best TWAS P=6.16e-08 · Best GWAS P=2.55e-07 conditioned to 0.0559
141M
141.2M
141.4M
141.6M
141.8M
142M
142.2M
142.4M
142.6M
142.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
PTK2
0.02
0.00
blup
538
0.01
8.6e-04
-4.9
5.4
6.2e-08
-0.70
0.05
0.53
TRUE
1
GTEx
Brain Caudate basal ganglia
PTK2
0.28
0.01
lasso
4
0.09
1.5e-03
-4.5
5.1
3.1e-07
-0.59
0.10
0.52
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
PTK2
0.05
0.07
lasso
4
0.07
5.4e-09
-5.1
5.1
3.1e-07
-0.98
0.04
0.96
FALSE