Best TWAS P=5.11e-10 · Best GWAS P=4.52e-12 conditioned to 0.00201
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | MROH1 | 0.22 | 0.20 | lasso | 4 | 0.15 | 1.1e-04 | 6.1 | 6.2 | 5.1e-10 | 0.86 | 0.01 | 0.93 | TRUE |
2 | GTEx | Skin Not Sun Exposed Suprapubic | GS1-393G12.12 | 0.09 | 0.05 | lasso | 4 | 0.03 | 9.8e-03 | 6.1 | 6.1 | 7.9e-10 | 0.83 | 0.01 | 0.85 | FALSE |
3 | GTEx | Thyroid | BOP1 | 0.19 | 0.10 | enet | 12 | 0.15 | 8.8e-12 | 6.9 | 5.7 | 9.3e-09 | 0.91 | 0.00 | 1.00 | FALSE |