TWAS
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Models
Genes
Traits
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Traits
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Impedance of whole body
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chr9:5,091,675-6,697,128
Best TWAS P=2.09e-08 · Best GWAS P=7.54e-12 conditioned to 4.21e-05
5M
5.2M
5.4M
5.6M
5.8M
6M
6.2M
6.4M
6.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
RANBP6
0.04
0.02
lasso
3
0.01
0.013
-6.3
5.6
2.1e-08
-0.70
0.05
0.85
TRUE
2
GTEx
Adipose Visceral Omentum
ERMP1
0.10
0.04
enet
9
0.03
0.012
-5.6
5.4
6.1e-08
-0.63
0.07
0.77
FALSE
3
GTEx
Nerve Tibial
ERMP1
0.12
0.00
lasso
4
0.01
0.079
1.1
5.4
6.8e-08
-0.69
0.03
0.85
FALSE