Best TWAS P=8.38e-09 · Best GWAS P=2.53e-10 conditioned to 0.00535
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRSS23 | 0.14 | 0.13 | lasso | 8 | 0.13 | 4.7e-16 | -4.0 | -5.5 | 3.3e-08 | -0.62 | 0.99 | 0.01 | FALSE |
| 2 | GTEx | Artery Tibial | ME3 | 0.24 | 0.06 | lasso | 8 | 0.11 | 4.1e-09 | -2.8 | 5.1 | 2.6e-07 | 0.31 | 0.08 | 0.90 | FALSE |
| 3 | GTEx | Pancreas | PRSS23 | 0.20 | 0.02 | lasso | 5 | 0.00 | 4.1e-01 | 5.1 | -5.8 | 8.4e-09 | -0.82 | 0.04 | 0.74 | TRUE |
| 4 | GTEx | Thyroid | PRSS23 | 0.18 | 0.09 | lasso | 9 | 0.14 | 1.2e-10 | -4.1 | -5.6 | 2.0e-08 | -0.48 | 0.70 | 0.30 | FALSE |