[Hub]/) : Traits : Impedance of whole body :

chr11:77,204,866-78,979,645

Best TWAS P=1.95e-09 · Best GWAS P=7.6e-10 conditioned to 0.111

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP35 0.06 0.05 blup 363 0.04 1.6e-05 4.8 5.2 2.2e-07 0.77 0.06 0.91 FALSE
2 GTEx Artery Aorta GAB2 0.10 0.02 lasso 4 0.02 1.7e-02 5.7 -5.1 2.9e-07 -0.80 0.06 0.70 FALSE
3 GTEx Artery Tibial GAB2 0.06 0.00 lasso 2 0.01 2.4e-02 5.7 -5.7 1.0e-08 -0.94 0.06 0.77 FALSE
4 GTEx Brain Cerebellar Hemisphere USP35 0.19 0.07 enet 13 0.09 2.5e-03 6.0 5.6 1.6e-08 0.95 0.06 0.76 FALSE
5 GTEx Brain Cerebellar Hemisphere NARS2 0.17 0.10 lasso 6 0.10 1.5e-03 4.5 -5.2 1.8e-07 -0.73 0.10 0.73 FALSE
6 GTEx Esophagus Muscularis GAB2 0.05 0.04 lasso 7 0.04 1.8e-03 5.0 -5.5 3.7e-08 -0.77 0.14 0.76 FALSE
7 GTEx Testis USP35 0.07 0.06 lasso 2 0.07 6.4e-04 6.0 6.0 2.1e-09 0.95 0.05 0.91 FALSE
8 METSIM Adipose USP35 0.05 0.05 lasso 11 0.04 3.0e-06 5.7 5.9 4.6e-09 0.96 0.05 0.95 FALSE
9 ROSMAP Brain Pre-frontal Cortex GAB2 0.05 0.00 blup 435 0.02 8.0e-04 5.8 -5.4 8.0e-08 -0.75 0.17 0.76 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme GAB2 0.10 0.07 blup 100 0.09 8.8e-04 6.0 -6.0 2.0e-09 -0.92 0.05 0.65 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma GAB2 0.06 0.06 blup 100 0.07 7.8e-08 5.7 -5.9 4.1e-09 -0.91 0.10 0.90 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma KCTD21 0.03 0.00 blup 51 0.01 7.2e-02 6.0 -5.4 8.3e-08 -0.86 0.01 0.65 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma GAB2 0.04 0.04 blup 100 0.04 1.4e-03 6.0 -6.0 2.1e-09 -0.95 0.04 0.90 FALSE