[Hub]/) : Traits : Impedance of whole body : ← →

chr15:44,959,112-46,410,543

Best TWAS P=3.32e-10 · Best GWAS P=4.29e-10 conditioned to 0.298

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
42	YFS	Blood	GATM	0.03	0.05	lasso	19	0.06	4.1e-19	-6.0	6.3	3.3e-10	-0.94	0.02	0.98	TRUE
58	The Cancer Genome Atlas	Lung Adenocarcinoma	GATM	0.04	0.01	blup	41	0.02	1.8e-03	-5.7	6.3	3.3e-10	-0.97	0.01	0.83	FALSE
60	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	GATM	0.02	0.01	blup	41	0.02	5.1e-03	-5.7	6.3	3.4e-10	-0.88	0.03	0.73	FALSE
65	The Cancer Genome Atlas	Prostate Adenocarcinoma	GATM	0.03	0.03	blup	41	0.04	7.3e-05	-5.8	6.3	3.5e-10	-0.86	0.05	0.94	FALSE
36	GTEx	Thyroid	GATM	0.14	0.13	lasso	5	0.17	8.4e-13	-5.7	6.2	4.0e-10	-0.91	0.04	0.96	FALSE
51	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GATM	0.02	0.01	blup	41	0.01	1.0e-02	-5.7	6.2	5.7e-10	-0.88	0.04	0.82	FALSE
63	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	GATM	0.09	0.10	lasso	1	0.09	1.6e-04	-6.1	6.1	1.2e-09	-0.75	0.05	0.84	FALSE
2	GTEx	Adipose Subcutaneous	SPATA5L1	0.15	0.21	enet	19	0.21	2.4e-17	-5.8	-6.0	1.6e-09	0.82	0.08	0.92	FALSE
70	The Cancer Genome Atlas	Thyroid Carcinoma	GATM	0.03	0.03	blup	41	0.02	1.7e-03	-5.7	6.0	1.7e-09	-0.80	0.06	0.80	FALSE
40	NTR	Blood	GATM	0.03	0.02	lasso	7	0.02	8.3e-08	-5.7	5.9	3.2e-09	-0.76	0.06	0.94	FALSE
47	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SPATA5L1	0.08	0.01	blup	33	0.03	1.2e-02	-5.6	-5.9	3.4e-09	0.89	0.02	0.64	FALSE
31	GTEx	Skin Sun Exposed Lower leg	GATM	0.11	0.11	lasso	7	0.11	3.5e-09	-5.7	5.9	3.5e-09	-0.72	0.08	0.92	FALSE
38	METSIM	Adipose	GATM	0.11	0.22	lasso	12	0.22	6.7e-33	-5.7	5.8	5.4e-09	-0.75	0.07	0.93	FALSE
16	GTEx	Esophagus Mucosa	SPATA5L1	0.17	0.14	enet	21	0.15	5.0e-10	-5.8	-5.8	5.8e-09	0.75	0.08	0.92	FALSE
3	GTEx	Adipose Visceral Omentum	SPATA5L1	0.15	0.14	enet	21	0.13	3.0e-07	-5.8	-5.8	6.2e-09	0.76	0.08	0.92	FALSE
18	GTEx	Esophagus Muscularis	SPATA5L1	0.24	0.24	lasso	4	0.24	4.7e-15	-5.7	-5.8	6.6e-09	0.74	0.08	0.92	FALSE
17	GTEx	Esophagus Mucosa	GATM	0.10	0.04	enet	20	0.10	5.7e-07	-5.2	5.8	7.2e-09	-0.89	0.08	0.92	FALSE
24	GTEx	Muscle Skeletal	SPATA5L1	0.10	0.12	lasso	6	0.10	1.9e-10	-5.7	-5.8	7.3e-09	0.73	0.08	0.92	FALSE
54	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SPATA5L1	0.12	0.17	lasso	7	0.15	3.7e-09	-5.8	-5.8	7.9e-09	0.72	0.04	0.96	FALSE
67	The Cancer Genome Atlas	Soft Tissue Sarcoma	SPATA5L1	0.05	0.07	enet	6	0.05	7.2e-04	-5.7	-5.8	7.9e-09	0.73	0.04	0.94	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SPATA5L1	0.12	0.24	lasso	7	0.24	6.8e-29	-5.7	-5.8	8.4e-09	0.72	0.08	0.92	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	SPATA5L1	0.17	0.18	enet	18	0.18	2.1e-06	-5.7	-5.8	8.4e-09	0.70	0.08	0.89	FALSE
32	GTEx	Small Intestine Terminal Ileum	SPATA5L1	0.23	0.26	lasso	1	0.26	1.6e-06	-5.8	-5.8	8.5e-09	0.72	0.07	0.80	FALSE
33	GTEx	Spleen	SPATA5L1	0.27	0.19	lasso	1	0.15	9.8e-05	-5.8	-5.8	8.5e-09	0.72	0.08	0.75	FALSE
50	The Cancer Genome Atlas	Glioblastoma Multiforme	SPATA5L1	0.13	0.10	enet	8	0.06	5.0e-03	-5.8	-5.8	8.6e-09	0.73	0.03	0.73	FALSE
56	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPATA5L1	0.10	0.18	enet	15	0.18	2.7e-20	-5.7	-5.8	8.6e-09	0.73	0.04	0.96	FALSE
69	The Cancer Genome Atlas	Stomach Adenocarcinoma	SPATA5L1	0.05	0.06	blup	33	0.06	2.9e-05	-5.8	-5.8	8.6e-09	0.77	0.04	0.95	FALSE
61	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SPATA5L1	0.06	0.09	enet	6	0.08	5.2e-06	-5.7	-5.8	8.7e-09	0.73	0.04	0.96	FALSE
7	GTEx	Artery Coronary	SPATA5L1	0.26	0.30	lasso	3	0.28	3.8e-10	-5.8	-5.8	8.9e-09	0.72	0.08	0.92	FALSE
30	GTEx	Skin Sun Exposed Lower leg	SPATA5L1	0.07	0.10	lasso	4	0.10	2.4e-08	-5.8	-5.8	8.9e-09	0.72	0.08	0.92	FALSE
4	GTEx	Adrenal Gland	SPATA5L1	0.16	0.21	lasso	3	0.18	6.3e-07	-5.6	-5.8	9.0e-09	0.71	0.09	0.90	FALSE
45	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATM	0.02	0.03	lasso	3	0.02	7.3e-06	-5.8	5.8	9.0e-09	-0.73	0.08	0.92	FALSE
64	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SPATA5L1	0.12	0.11	enet	14	0.11	3.1e-05	-5.7	-5.8	9.2e-09	0.73	0.04	0.92	FALSE
12	GTEx	Cells Transformed fibroblasts	SPATA5L1	0.30	0.41	lasso	5	0.41	9.7e-33	-5.8	-5.7	9.3e-09	0.73	0.08	0.92	FALSE
26	GTEx	Nerve Tibial	SPATA5L1	0.20	0.33	lasso	10	0.33	5.3e-24	-5.8	-5.7	9.4e-09	0.72	0.08	0.92	FALSE
41	NTR	Blood	SPATA5L1	0.05	0.08	lasso	11	0.08	1.6e-25	-5.7	-5.7	9.6e-09	0.76	0.08	0.92	FALSE
55	The Cancer Genome Atlas	Brain Lower Grade Glioma	GATM	0.02	0.02	enet	8	0.02	1.8e-03	-5.7	5.7	9.6e-09	-0.73	0.07	0.83	FALSE
66	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPATA5L1	0.14	0.21	lasso	2	0.21	1.5e-21	-5.7	-5.7	9.6e-09	0.73	0.04	0.96	FALSE
19	GTEx	Heart Atrial Appendage	SPATA5L1	0.15	0.10	lasso	5	0.06	1.4e-03	-5.8	-5.7	9.7e-09	0.72	0.07	0.88	FALSE
62	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPATA5L1	0.13	0.21	lasso	7	0.20	1.1e-08	-5.7	-5.7	9.8e-09	0.73	0.04	0.96	FALSE
13	GTEx	Colon Sigmoid	SPATA5L1	0.17	0.21	lasso	3	0.18	6.4e-07	-5.8	-5.7	9.9e-09	0.72	0.08	0.92	FALSE
6	GTEx	Artery Aorta	SPATA5L1	0.24	0.30	enet	13	0.29	2.1e-16	-5.7	-5.7	1.0e-08	0.73	0.08	0.92	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	SPATA5L1	0.18	0.20	lasso	10	0.14	8.2e-06	-5.8	-5.7	1.0e-08	0.73	0.09	0.91	FALSE
25	GTEx	Muscle Skeletal	GATM	0.13	0.10	lasso	6	0.11	9.3e-11	-5.7	-5.7	1.1e-08	0.72	0.08	0.92	FALSE
39	METSIM	Adipose	SPATA5L1	0.16	0.26	lasso	20	0.25	2.0e-37	-5.8	-5.7	1.1e-08	0.73	0.08	0.92	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	SPATA5L1	0.07	0.09	lasso	3	0.08	3.0e-05	-5.6	-5.7	1.1e-08	0.72	0.04	0.96	FALSE
27	GTEx	Nerve Tibial	GATM	0.07	0.04	lasso	2	0.08	1.9e-06	2.3	5.7	1.2e-08	-0.49	0.08	0.83	FALSE
43	YFS	Blood	SPATA5L1	0.21	0.45	lasso	16	0.45	7.5e-166	-5.7	-5.7	1.2e-08	0.74	0.09	0.91	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	SPATA5L1	0.05	0.08	lasso	2	0.07	7.6e-15	-5.7	-5.7	1.2e-08	0.73	0.04	0.96	FALSE
14	GTEx	Colon Transverse	SPATA5L1	0.19	0.16	lasso	2	0.14	2.7e-07	-5.7	-5.7	1.3e-08	0.73	0.08	0.92	FALSE
35	GTEx	Thyroid	SPATA5L1	0.19	0.23	lasso	6	0.23	1.6e-17	-5.7	-5.7	1.4e-08	0.71	0.08	0.92	FALSE
37	GTEx	Whole Blood	SPATA5L1	0.24	0.26	lasso	5	0.26	2.4e-24	-5.8	-5.7	1.4e-08	0.71	0.08	0.92	FALSE
9	GTEx	Breast Mammary Tissue	SPATA5L1	0.31	0.17	lasso	7	0.18	2.4e-09	-5.8	-5.7	1.5e-08	0.70	0.08	0.92	FALSE
48	The Cancer Genome Atlas	Colon Adenocarcinoma	GATM	0.35	0.18	blup	41	0.18	2.4e-10	-6.0	5.7	1.6e-08	-0.95	0.02	0.98	FALSE
71	The Cancer Genome Atlas	Thyroid Carcinoma	SPATA5L1	0.16	0.24	enet	8	0.26	1.4e-25	-5.7	-5.7	1.6e-08	0.71	0.04	0.96	FALSE
21	GTEx	Heart Left Ventricle	SPATA5L1	0.10	0.09	enet	9	0.06	4.3e-04	-5.8	-5.6	1.7e-08	0.72	0.08	0.90	FALSE
52	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPATA5L1	0.12	0.15	enet	4	0.15	1.9e-16	-5.6	-5.6	1.8e-08	0.72	0.05	0.95	FALSE
34	GTEx	Testis	SPATA5L1	0.17	0.07	lasso	4	0.04	5.5e-03	-5.7	-5.6	2.7e-08	0.73	0.07	0.92	FALSE
8	GTEx	Artery Tibial	SPATA5L1	0.21	0.21	enet	20	0.22	4.6e-17	-5.8	-5.5	2.9e-08	0.68	0.08	0.92	FALSE
57	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SPATA5L1	0.09	0.07	lasso	5	0.07	3.9e-04	-5.6	-5.5	4.1e-08	0.68	0.04	0.87	FALSE
5	GTEx	Adrenal Gland	GATM	0.14	0.02	lasso	4	0.02	5.7e-02	-5.8	5.5	4.3e-08	-0.56	0.06	0.47	FALSE
20	GTEx	Heart Atrial Appendage	GATM	0.13	0.09	lasso	5	0.08	2.8e-04	-5.7	-5.5	4.3e-08	0.72	0.07	0.76	FALSE
10	GTEx	Breast Mammary Tissue (Female)	SPATA5L1	0.30	0.16	lasso	3	0.16	1.3e-05	-5.1	-5.4	5.9e-08	0.71	0.09	0.88	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	SPATA5L1	0.08	0.08	lasso	4	0.07	1.6e-04	-5.8	-5.4	7.0e-08	0.70	0.08	0.83	FALSE
22	GTEx	Lung	SPATA5L1	0.15	0.14	lasso	8	0.12	2.0e-09	-5.8	-5.3	8.6e-08	0.66	0.08	0.92	FALSE
44	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SPATA5L1	0.07	0.06	blup	33	0.05	3.9e-05	-5.7	-5.3	1.1e-07	0.65	0.04	0.94	FALSE
28	GTEx	Pancreas	SPATA5L1	0.15	0.12	lasso	4	0.14	1.6e-06	-5.8	-5.3	1.4e-07	0.66	0.07	0.88	FALSE
68	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SPATA5L1	0.16	0.08	lasso	2	0.10	1.5e-03	-4.1	-5.2	1.9e-07	0.60	0.02	0.32	FALSE
23	GTEx	Lung	GATM	0.04	0.04	lasso	2	0.02	8.2e-03	-5.2	5.2	2.1e-07	-0.89	0.07	0.75	FALSE
53	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC28A2	0.03	0.04	blup	55	0.03	7.3e-03	-5.3	5.2	2.1e-07	-0.89	0.03	0.56	FALSE
59	The Cancer Genome Atlas	Lung Adenocarcinoma	SPATA5L1	0.05	0.03	blup	33	0.03	2.2e-04	-5.7	-5.2	2.1e-07	0.70	0.04	0.95	FALSE