Hub : Genes

GATM

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.1359 0.0628 5.7e-03 0.016 NA -0.005 NA 0.021 8.5e-02 NA 5.3e-01 NA 5.7e-02
2 GTEx Artery Tibial 0.1087 0.0334 2.4e-06 0.107 NA 0.082 NA 0.075 9.2e-09 NA 5.8e-07 NA 1.7e-06
3 GTEx Colon Sigmoid 0.0960 0.0500 8.8e-03 0.012 NA -0.008 NA 0.004 1.2e-01 NA 7.7e-01 NA 2.3e-01
4 GTEx Esophagus Mucosa 0.1010 0.0400 2.3e-05 0.044 NA 0.096 NA 0.073 6.2e-04 NA 5.7e-07 NA 1.3e-05
5 GTEx Heart Atrial Appendage 0.1320 0.0640 3.5e-03 0.088 NA 0.045 NA 0.076 8.9e-05 NA 4.2e-03 NA 2.8e-04
6 GTEx Lung 0.0435 0.0232 6.2e-03 0.035 NA -0.002 NA 0.022 9.6e-04 NA 5.0e-01 NA 8.2e-03
7 GTEx Muscle Skeletal 0.1320 0.0394 2.0e-10 0.104 NA 0.107 NA 0.108 2.1e-10 NA 1.2e-10 NA 9.3e-11
8 GTEx Nerve Tibial 0.0690 0.0320 3.1e-03 0.036 NA 0.063 NA 0.082 1.4e-03 NA 3.1e-05 NA 1.9e-06
9 GTEx Skin Sun Exposed Lower leg 0.1050 0.0310 8.6e-08 0.107 NA 0.086 NA 0.107 3.7e-09 NA 1.3e-07 NA 3.5e-09
10 GTEx Thyroid 0.1430 0.0390 1.1e-10 0.131 NA 0.153 NA 0.167 3.0e-10 NA 9.5e-12 NA 8.4e-13
11 METSIM Adipose 0.1079 0.0258 0.0e+00 0.223 0.177 0.219 0.210 0.224 7.5e-33 8.3e-26 3.7e-32 8.0e-31 6.7e-33
12 NTR Blood 0.0265 0.0096 4.2e-07 0.020 0.020 0.019 0.020 0.022 2.8e-07 4.5e-07 7.5e-07 2.8e-07 8.2e-08
13 YFS Blood 0.0343 0.0099 3.9e-16 0.049 0.053 0.054 0.054 0.061 1.0e-15 6.6e-17 3.1e-17 4.2e-17 4.1e-19
14 TCGA Breast Invasive Carcinoma 0.0210 0.0132 6.0e-06 0.026 0.023 0.024 NA 0.024 3.6e-06 1.0e-05 7.7e-06 NA 7.3e-06
15 TCGA Colon Adenocarcinoma 0.3530 0.1430 1.1e-10 0.176 0.175 0.165 NA 0.162 2.1e-10 2.4e-10 8.1e-10 NA 1.2e-09
16 TCGA Esophageal Carcinoma 0.1060 0.0820 6.4e-03 0.097 0.035 0.030 NA 0.019 5.3e-04 2.8e-02 3.9e-02 NA 7.9e-02
17 TCGA Head and Neck Squamous Cell Carcinoma 0.0234 0.0180 1.5e-03 0.012 0.014 0.006 NA 0.003 1.5e-02 1.0e-02 6.0e-02 NA 1.3e-01
18 TCGA Brain Lower Grade Glioma 0.0247 0.0174 9.6e-04 0.020 0.018 0.021 NA 0.015 2.1e-03 3.4e-03 1.8e-03 NA 7.5e-03
19 TCGA Lung Adenocarcinoma 0.0364 0.0356 2.4e-03 0.012 0.020 0.017 NA 0.019 1.3e-02 1.8e-03 4.2e-03 NA 2.6e-03
20 TCGA Lung Squamous Cell Carcinoma 0.0199 0.0169 4.6e-03 0.009 0.016 0.004 NA 0.011 2.9e-02 5.1e-03 1.1e-01 NA 1.8e-02
21 TCGA Pheochromocytoma and Paraganglioma 0.0880 0.0560 4.4e-04 0.105 0.075 0.077 NA 0.093 6.1e-05 6.5e-04 5.6e-04 NA 1.6e-04
22 TCGA Prostate Adenocarcinoma 0.0321 0.0217 4.9e-05 0.032 0.038 0.032 NA 0.030 2.4e-04 7.3e-05 2.4e-04 NA 3.5e-04
23 TCGA Thyroid Carcinoma 0.0270 0.0200 1.1e-03 0.030 0.025 0.021 NA 0.022 6.5e-04 1.7e-03 3.8e-03 NA 3.1e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 1.1 1.8 4.4 2.1 -1.2 -2.0 1.5 -1.0 1.6 -1.1 0.9 0.8 1.4 1.1 1.1 1.5 1.1 1.7 0.9 1.3 1.2 1.5 1.4 1.0 1.3 1.2
Bipolar Disorder or Schizophrenia 0.2 0.4 1.8 1.3 -0.9 -0.9 0.7 -0.6 0.1 -0.6 -0.2 0.3 0.7 0.6 0.5 0.5 0.6 0.8 0.4 0.7 0.6 0.8 0.7 0.2 0.7 0.7
Depressed Affect (Nagel 2018) 0.4 0.8 1.9 -1.2 0.7 -1.4 -0.2 0.8 0.4 1.1 0.1 -1.1 -0.8 -1.1 -1.0 -0.4 -1.0 -0.2 -1.1 -0.9 -1.1 -0.6 -0.8 -0.8 -0.8 -1.0
Depression (Nagel 2018) 3.9 5.9 8.8 -2.0 1.8 0.9 -2.5 2.1 -2.7 2.4 -1.8 -2.4 -2.8 -2.4 -2.5 -2.7 -2.3 -2.7 -1.9 -2.8 -2.4 -3.0 -2.8 -2.4 -2.7 -2.6
Intelligence (Savage-Jansen 2018) 0.1 0.2 0.8 0.1 0.3 0.3 -0.5 0.7 -0.5 0.5 0.9 -0.5 -0.2 -0.5 -0.4 -0.3 -0.4 -0.1 -0.6 -0.3 -0.5 -0.2 -0.4 -0.7 -0.4 -0.4
Neuroticism (Nagel 2018) 0.1 0.1 1.4 -0.4 -0.5 -1.2 0.2 -0.3 0.4 -0.2 0.9 -0.0 -0.0 -0.0 0.1 0.2 0.1 -0.1 0.1 0.0 0.1 -0.0 0.0 -0.1 0.0 0.0
Schizophrenia (2018) 0.1 0.2 1.4 0.0 -0.0 1.0 -0.3 0.1 -1.2 0.2 -1.0 -0.3 -0.2 -0.1 -0.2 -0.5 -0.1 -0.4 -0.2 -0.2 -0.2 -0.2 -0.2 -0.5 -0.2 -0.1
Schizophrenia vs Biploar Disorder 0.2 0.2 1.1 -1.1 0.9 0.4 -0.5 0.7 0.0 0.5 -0.0 -0.5 -0.3 -0.6 -0.4 -0.2 -0.5 0.3 -0.6 -0.4 -0.5 -0.2 -0.3 -0.3 -0.3 -0.4
Worry (Nagel 2018) 1.0 2.1 4.2 1.1 -2.0 -0.9 1.4 -1.6 1.4 -1.5 2.1 1.4 1.4 1.5 1.5 1.4 1.5 0.8 1.5 1.4 1.5 1.3 1.3 1.1 1.4 1.5
Alzheimer’s Disease (in mother) 0.4 0.5 1.2 -0.8 0.6 -0.1 -0.5 0.4 -0.4 0.6 -0.2 -0.7 -0.9 -0.7 -0.7 -0.9 -0.6 -1.1 -0.4 -0.8 -0.6 -0.9 -0.8 -0.6 -0.8 -0.7
Alzheimer’s Disease (in father) 2.8 3.1 4.7 -1.3 2.2 1.6 -1.4 1.7 -1.3 1.9 -1.0 -1.7 -1.9 -2.0 -1.9 -1.8 -1.9 -1.0 -1.7 -2.0 -1.9 -2.0 -1.9 -1.8 -1.9 -2.0
Alzheimer’s Disease (including proxy) 2.2 3.2 4.5 -1.9 1.6 0.9 -1.5 1.7 -1.7 1.9 -0.5 -1.8 -2.1 -1.9 -1.9 -2.1 -1.8 -1.8 -1.5 -2.1 -1.8 -2.1 -2.0 -1.7 -2.0 -2.0
Crohns Disease (2017) 1.8 4.0 8.0 -2.3 0.8 -0.0 -1.8 1.9 -2.1 1.9 -2.8 -2.1 -2.1 -2.0 -1.9 -2.2 -1.9 -2.4 -1.6 -2.0 -1.9 -2.0 -2.1 -2.1 -2.1 -1.9
Irritable Bowel Disease (IBD) 0.8 1.8 5.2 -1.4 -0.2 -1.0 -1.2 1.2 -1.7 1.1 -0.7 -1.4 -1.6 -1.2 -1.2 -1.7 -1.2 -2.3 -0.7 -1.4 -1.1 -1.7 -1.5 -1.2 -1.5 -1.2
Ulcerative Colitis (UC) 0.1 0.2 1.4 0.0 -0.9 -1.2 0.0 0.0 -0.5 -0.2 1.1 -0.0 -0.4 0.1 0.0 -0.3 -0.0 -0.9 0.4 -0.2 0.1 -0.6 -0.2 0.1 -0.2 0.0
Major Depression (MDD) 0.2 0.2 1.6 0.7 -0.3 1.3 0.1 0.0 -0.3 -0.1 1.2 0.2 0.2 0.2 0.3 0.1 0.2 0.1 0.1 0.3 0.1 0.4 0.3 0.4 0.3 0.2
Reaction Time 0.2 0.5 2.1 0.1 -0.5 -0.2 0.1 -0.9 0.5 -0.5 1.4 0.3 0.8 0.4 0.6 0.9 0.5 1.0 0.3 0.7 0.5 0.9 0.7 0.8 0.7 0.6
Verbal and Numeric Reasoning (VNR) 0.3 0.7 3.4 0.6 -0.2 -0.2 0.5 -0.7 0.4 -0.6 1.8 0.6 1.1 0.5 0.7 1.1 0.6 1.4 0.3 1.0 0.6 1.2 1.0 0.6 0.9 0.8
Breast Cancer 0.1 0.3 1.5 0.5 -0.9 -1.0 1.0 -0.7 1.2 -0.4 -0.5 0.1 0.0 0.5 0.5 0.3 0.4 -0.6 0.6 0.2 0.4 0.1 0.1 0.5 0.2 0.3
Ovarian Cancer 0.3 0.3 1.3 -0.4 -0.8 -0.5 0.3 -0.6 0.4 -0.5 1.2 0.3 0.7 0.4 0.4 0.6 0.5 0.7 0.3 0.7 0.5 0.8 0.6 0.2 0.6 0.6
Prostate Cancer 0.2 0.2 2.2 0.4 -0.2 -1.5 0.7 -0.2 0.4 -0.2 -0.9 0.5 0.0 0.5 0.2 0.1 0.2 0.0 0.4 0.1 0.3 -0.1 0.1 0.6 0.2 0.2
Age at First Birth 0.6 0.9 3.4 -0.8 1.3 1.8 -0.6 1.0 -0.8 0.8 0.4 -0.4 -1.0 -0.9 -0.7 -0.9 -0.9 -0.5 -0.7 -1.1 -0.8 -1.2 -0.9 -0.7 -1.0 -1.0
Bipolar Disorder (2011) 0.2 0.2 0.5 -0.7 0.4 -0.6 0.6 0.5 0.7 0.3 -0.2 -0.5 0.1 -0.3 -0.2 0.2 -0.3 0.7 -0.6 -0.0 -0.3 0.3 0.0 -0.5 -0.0 -0.2
Body Mass Index (BMI) (2010) 0.4 0.6 1.9 -0.2 0.6 0.2 -0.5 1.0 -1.4 0.5 -0.8 -0.5 -0.8 -0.6 -0.6 -1.1 -0.5 -1.3 -0.3 -0.8 -0.5 -1.0 -0.8 -0.8 -0.8 -0.6
Coronary Artery Disease (CAD) 3.8 4.6 9.9 3.0 -3.1 -1.4 1.5 -2.4 -0.6 -2.4 2.0 2.6 2.0 2.6 2.4 1.4 2.3 0.2 2.5 2.0 2.3 1.4 1.9 2.4 2.0 2.3
Crohns Disease (2012) 2.3 3.7 10.2 -1.5 1.2 1.4 -2.1 2.0 -1.9 1.8 -3.2 -1.8 -1.9 -1.9 -1.9 -2.1 -1.8 -2.2 -1.6 -1.9 -1.8 -1.9 -2.0 -2.0 -1.9 -1.8
Mean Putamen Volume 0.8 0.9 7.0 1.4 -0.9 -2.6 0.1 -0.5 0.8 -0.9 -1.2 0.8 0.5 0.8 0.9 0.6 0.8 0.1 1.1 0.6 0.8 0.2 0.6 1.0 0.7 0.7
Fasting Glucose 0.8 0.9 3.2 1.1 -1.8 -0.7 0.5 -1.0 -0.7 -1.2 -0.3 1.1 0.6 1.2 1.2 0.2 1.3 -0.6 1.5 0.7 1.1 0.1 0.6 0.9 0.7 1.0
HbA1C 0.3 0.4 1.8 1.0 -0.3 1.4 -0.9 0.5 -0.9 -0.9 -0.8 0.5 -0.4 -0.4 -0.5 -0.5 -0.4 -0.8 -0.1 -0.4 -0.1 -0.5 -0.4 -0.2 -0.3 -0.2
HDL Cholesterol 0.5 0.8 1.8 1.0 -0.8 0.6 1.2 -1.0 0.0 -0.9 1.3 1.1 0.8 1.2 0.9 0.7 0.9 0.8 0.8 0.8 0.8 0.7 0.9 0.8 0.8 0.8
LDL Cholesterol 0.3 0.5 2.0 1.4 -0.8 -0.0 0.4 -1.1 -0.3 -0.7 0.6 0.7 0.8 0.8 0.6 0.7 0.6 0.6 0.6 0.8 0.7 0.7 0.7 0.5 0.7 0.7
Lupus 2.9 4.3 5.3 -2.1 2.3 2.1 -1.7 2.1 -1.5 2.2 -2.2 -2.0 -2.0 -2.2 -2.2 -2.2 -2.3 -1.3 -2.3 -2.2 -2.3 -1.9 -2.1 -2.0 -2.2 -2.3
Neuroticism (2016) 0.1 0.2 0.7 -0.1 0.4 -0.6 0.7 -0.1 0.8 -0.1 0.5 -0.1 0.5 -0.0 0.1 0.7 -0.0 0.8 -0.2 0.4 0.1 0.7 0.4 -0.2 0.4 0.2
Primary Biliary Cirrhosis 3.3 4.6 7.7 2.5 -2.8 -0.1 2.0 -2.5 0.4 -2.7 1.4 2.6 2.0 2.4 2.5 1.6 2.6 0.6 2.8 2.1 2.6 1.4 2.1 2.1 2.2 2.5
Rheumatoid Arthritis 0.4 0.6 5.4 -0.1 -1.1 1.4 0.6 -0.6 -0.2 -0.6 2.3 0.5 0.3 0.6 0.5 0.2 0.5 -0.3 0.7 0.4 0.5 0.2 0.3 0.5 0.4 0.5
Schizophrenia (2014) 0.0 0.1 0.7 0.8 -0.3 0.4 0.2 -0.2 -0.4 -0.1 -0.7 0.1 0.2 0.1 0.1 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.2 -0.0 0.2 0.1
Triglycerides 0.2 0.4 2.1 -0.2 -0.2 -0.2 -1.0 0.4 -0.8 0.3 -0.4 -0.5 -0.6 -0.5 -0.3 -1.0 -0.2 -1.5 -0.1 -0.5 -0.3 -0.8 -0.7 -0.8 -0.6 -0.4
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.4 -0.1 -0.1 0.1 -0.9 0.5 -1.2 0.3 -0.5 -0.1 -0.6 -0.1 -0.4 -0.8 -0.3 -1.0 -0.1 -0.6 -0.5 -0.8 -0.6 -0.5 -0.5 -0.4
Ulcerative Colitis 1.0 1.5 6.6 1.0 -2.4 -1.5 0.1 -1.3 -0.6 -1.3 2.6 1.0 0.4 1.1 1.1 0.2 1.1 -0.8 1.7 0.7 1.3 -0.0 0.6 1.3 0.7 1.0
Blood Eosinophil Count 0.7 5.1 8.7 1.2 -1.4 -2.9 2.5 -2.1 3.0 -2.1 1.7 2.1 2.4 2.3 2.2 2.5 2.1 2.8 1.8 2.3 2.2 2.3 2.4 2.0 2.4 2.2
Blood Platelet Count 1.0 11.2 14.3 2.3 -2.7 -1.1 3.5 -3.5 2.8 -3.6 2.1 3.6 3.8 3.6 3.6 3.7 3.7 3.5 3.2 3.7 3.6 3.6 3.8 3.3 3.8 3.7
Blood Red Count 0.8 7.8 10.8 2.0 -2.1 -3.1 2.5 -3.3 2.4 -3.1 1.8 2.7 2.9 3.0 3.0 2.6 3.0 2.5 3.0 3.0 3.1 2.6 3.0 2.8 3.0 3.0
Blood White Count 0.0 0.2 1.0 -0.7 -0.2 0.2 -0.8 0.0 -0.2 0.3 0.1 -0.7 -0.6 -0.4 -0.2 -0.6 -0.3 -1.0 -0.1 -0.4 -0.3 -0.5 -0.6 -0.5 -0.5 -0.3
Heel T-Score 0.7 5.6 12.7 -0.6 1.9 -0.0 -2.3 2.6 -1.8 2.5 -3.6 -2.5 -2.4 -2.6 -2.5 -2.4 -2.5 -2.3 -2.5 -2.4 -2.5 -2.1 -2.4 -2.7 -2.4 -2.4
BMI 0.6 3.7 13.8 -1.8 1.5 -0.2 -1.7 1.6 -1.0 1.8 -3.7 -2.1 -2.2 -1.7 -1.8 -2.1 -1.8 -2.1 -1.3 -2.0 -1.8 -2.2 -2.1 -1.8 -2.1 -1.9
Height 0.2 4.3 11.7 -3.4 1.8 1.8 -1.9 2.1 -1.5 2.2 -1.1 -2.2 -1.9 -2.3 -2.3 -1.8 -2.2 -1.2 -2.3 -2.0 -2.2 -1.6 -2.0 -2.3 -2.0 -2.1
Waist Hip Ratio (WHR) 0.5 2.3 5.4 1.6 -2.3 -1.3 1.4 -1.7 0.1 -1.8 0.9 1.9 1.2 1.8 1.7 1.0 1.7 0.2 2.0 1.3 1.8 0.7 1.4 1.7 1.5 1.6
Systolic Blood Pressure 0.2 1.1 4.9 1.7 -2.2 1.0 0.4 -1.2 -0.1 -1.1 1.1 1.1 0.5 1.2 1.1 0.3 1.1 -1.0 1.5 0.7 1.1 0.2 0.5 0.9 0.6 1.0
Smoking Status 1.0 2.4 10.0 1.5 -2.2 1.6 1.4 -2.1 0.6 -1.6 3.2 1.7 1.0 1.5 1.6 0.9 1.6 -0.1 1.9 1.2 1.6 0.7 1.1 1.4 1.2 1.5
Allergy or Eczema 0.7 1.9 3.3 -1.1 1.4 1.8 -1.4 1.5 -0.9 1.4 -0.1 -1.3 -1.5 -1.3 -1.6 -1.4 -1.5 -1.0 -1.3 -1.5 -1.5 -1.4 -1.5 -1.4 -1.5 -1.5
Cardiovascular Disease 0.1 0.5 2.5 0.8 -1.6 -0.0 0.1 -1.0 0.6 -0.8 0.1 0.4 0.4 0.7 0.8 0.3 0.9 -0.6 0.9 0.6 0.8 0.3 0.4 0.3 0.5 0.7
Hypothyroidism (self reported) 0.2 0.4 1.9 0.4 -0.5 -0.7 -0.4 -0.0 -0.4 0.3 -1.4 -0.3 -0.8 -0.3 -0.3 -0.8 -0.3 -1.3 0.1 -0.6 -0.3 -0.9 -0.6 -0.3 -0.6 -0.4
Respiratory disease 0.7 1.6 2.8 1.1 -0.9 0.6 1.0 -1.4 0.4 -1.5 0.4 1.6 1.4 1.7 1.4 1.1 1.5 1.4 1.4 1.4 1.5 1.0 1.4 1.3 1.4 1.4
Type 2 Diabetes (T2D) (2018) 1.3 2.5 4.6 0.3 -0.9 -1.1 2.0 -1.4 2.1 -1.5 0.5 1.3 1.9 1.5 1.6 1.9 1.6 2.1 1.3 1.8 1.6 1.9 1.8 1.2 1.7 1.6
Lung FEV1/FVC ratio 0.2 1.0 2.0 0.3 -1.0 0.5 0.7 -1.2 -1.0 -1.3 0.2 1.2 1.0 1.2 1.2 0.5 1.3 0.6 1.4 1.1 1.3 0.5 1.0 0.9 1.0 1.2
Lung FVC 0.6 2.9 5.0 1.4 -2.1 -1.7 1.5 -1.5 1.2 -1.8 2.2 1.9 1.5 1.8 1.8 1.7 1.8 0.9 1.9 1.6 1.8 1.3 1.6 2.0 1.7 1.8
Neuroticism 0.3 0.7 2.9 0.0 -0.5 -1.6 1.1 -0.5 1.7 -0.3 1.4 0.4 0.8 0.4 0.5 1.2 0.4 1.1 0.0 0.7 0.4 1.0 0.7 0.3 0.7 0.5
Chronotype (morning person) 0.1 0.3 1.9 1.4 -0.3 -0.6 -0.3 -0.3 -1.2 -0.3 -0.6 0.4 -0.2 0.3 0.1 -0.4 0.3 -0.3 0.5 -0.2 0.3 -0.7 -0.1 -0.1 -0.0 0.1
Hair Pigment 0.1 1.9 8.3 -0.2 0.3 0.9 -2.2 0.7 -2.9 0.9 -0.4 -1.0 -1.5 -0.9 -1.0 -2.0 -0.9 -2.5 -0.4 -1.3 -0.9 -1.9 -1.4 -1.0 -1.4 -1.0
Tanning 0.0 0.5 1.3 1.2 -0.3 1.0 0.8 -0.6 0.7 -0.6 -0.0 0.7 0.9 0.5 0.5 0.8 0.6 0.9 0.3 0.8 0.6 0.9 0.8 0.1 0.8 0.7
Hand grip strength (left) 2.2 5.9 8.7 -2.9 2.2 0.7 -2.4 2.4 -2.0 2.5 -1.6 -2.6 -2.6 -2.5 -2.6 -2.6 -2.6 -2.3 -2.3 -2.6 -2.6 -2.5 -2.7 -2.5 -2.7 -2.6
Number of treatments/medications taken 0.3 0.5 1.0 -0.4 0.9 0.8 -0.8 0.4 0.0 0.9 -0.8 -1.0 -0.7 -0.9 -0.7 -0.5 -0.8 -0.3 -0.7 -0.7 -0.8 -0.5 -0.7 -0.4 -0.8 -0.8
Average weekly spirits intake 0.1 0.1 0.3 -0.4 0.5 0.0 0.1 0.1 0.5 0.4 0.2 -0.4 -0.1 -0.3 -0.3 -0.0 -0.3 0.4 -0.5 -0.2 -0.3 0.0 -0.1 -0.4 -0.2 -0.3
Sensitivity / hurt feelings 1.2 2.0 3.2 1.0 -1.8 -1.4 1.7 -1.7 1.5 -1.4 0.8 1.4 1.4 1.4 1.4 1.6 1.4 1.1 1.3 1.4 1.4 1.4 1.4 1.2 1.5 1.5
Frequency of depressed mood in last 2 weeks 1.2 1.7 2.7 -1.0 1.0 0.9 -1.0 1.0 -1.1 1.4 -1.0 -1.2 -1.6 -1.3 -1.4 -1.4 -1.3 -1.3 -1.1 -1.6 -1.3 -1.6 -1.5 -1.3 -1.5 -1.4
Hearing difficulty/problems: Yes 0.8 1.3 2.8 -1.7 0.6 1.7 -1.3 1.0 -0.8 1.1 -1.0 -1.1 -1.2 -1.1 -1.2 -1.1 -1.1 -1.1 -0.8 -1.1 -1.1 -1.0 -1.2 -1.0 -1.2 -1.1
Relative age of first facial hair 0.1 0.2 0.9 0.3 -0.7 -0.7 -0.4 -0.2 -0.9 0.1 -0.6 -0.3 -0.3 -0.3 -0.2 -0.5 -0.1 -0.7 -0.0 -0.2 -0.1 -0.4 -0.3 -0.6 -0.3 -0.1
Other serious medical condition/disability diagnosed by doctor 1.7 2.2 3.3 -0.9 1.2 1.6 -1.8 1.4 -1.3 1.6 0.4 -1.8 -1.5 -1.8 -1.6 -1.5 -1.5 -1.4 -1.5 -1.5 -1.6 -1.3 -1.6 -1.5 -1.6 -1.6
Ever used hormone-replacement therapy (HRT) 1.0 1.3 1.8 -1.1 1.4 0.5 -1.2 1.1 -0.9 1.3 -0.3 -1.3 -1.2 -1.3 -1.2 -1.0 -1.3 -0.6 -1.2 -1.2 -1.3 -1.1 -1.2 -1.1 -1.2 -1.3
Ever had hysterectomy (womb removed) 0.1 0.1 0.6 0.3 -0.0 -0.8 0.1 -0.0 0.7 -0.1 0.0 -0.0 0.4 0.1 0.3 0.4 0.2 0.3 0.0 0.3 0.1 0.5 0.3 0.2 0.3 0.3
Systolic blood pressure, automated reading 0.1 0.3 2.9 -0.0 -1.3 0.6 -0.4 -0.0 -0.6 -0.2 -0.3 0.1 -0.4 0.1 0.2 -0.5 0.2 -1.7 0.6 -0.1 0.2 -0.4 -0.4 0.2 -0.2 0.1
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.6 -0.8 0.7 0.0 0.4 0.1 0.7 0.2 -0.4 -0.3 -0.2 -0.2 -0.4 -0.0 -0.3 0.2 -0.3 -0.2 -0.3 -0.2 -0.2 -0.3 -0.2 -0.3
Angina 0.1 0.1 0.9 0.9 -0.9 0.3 -0.3 -0.1 -0.3 -0.2 0.4 -0.1 -0.1 -0.0 0.2 -0.3 0.2 -0.8 0.2 0.0 0.2 -0.2 -0.1 -0.4 -0.0 0.2
Medication for hormone replacement therapy 0.5 0.5 2.9 -0.5 1.0 1.7 -0.6 0.8 -1.0 0.7 -0.6 -0.5 -0.6 -0.7 -0.6 -0.5 -0.6 -0.1 -0.6 -0.6 -0.7 -0.6 -0.6 -0.6 -0.7 -0.7
Vitamin and mineral supplements 1.1 1.5 3.1 1.0 -1.3 -1.8 1.1 -1.3 1.2 -1.2 1.2 0.8 1.4 1.0 1.1 1.1 1.2 1.1 1.0 1.4 1.2 1.4 1.3 0.7 1.3 1.3
Supplements: Zinc 0.5 0.6 1.0 -0.7 1.0 0.6 -0.2 0.6 -0.6 0.9 0.0 -0.5 -0.7 -0.8 -0.9 -0.6 -0.9 -0.2 -1.0 -0.9 -0.9 -0.8 -0.7 -0.9 -0.8 -0.9
Medication: Co-codamol 0.1 0.1 0.3 0.1 -0.2 0.1 0.2 -0.4 0.5 -0.3 -0.5 0.4 0.3 0.4 0.2 0.4 0.3 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.3 0.3
Medication: Metformin 0.3 0.5 2.8 -0.9 0.9 -0.2 1.2 0.2 1.7 0.1 -0.2 -0.2 0.6 -0.0 0.1 0.8 -0.0 1.3 -0.3 0.5 -0.0 1.0 0.4 0.1 0.3 0.1
Diabetes (father) 1.5 1.9 4.9 -2.2 2.2 -0.4 -1.8 1.6 -1.1 1.5 -0.9 -1.6 -1.2 -1.5 -1.3 -1.2 -1.4 -0.2 -1.4 -1.3 -1.4 -1.1 -1.2 -1.0 -1.3 -1.5
Diabetes (mother) 0.1 0.2 0.8 0.3 0.9 -0.5 0.3 0.1 0.3 0.0 -0.5 -0.4 0.3 -0.5 -0.2 0.1 -0.1 0.7 -0.5 0.1 -0.1 0.3 0.2 -0.8 0.1 -0.0
Severe depression (siblings) 1.3 1.5 2.9 0.9 -1.7 -0.8 1.2 -1.4 0.9 -1.2 0.5 1.3 1.3 1.4 1.2 1.3 1.2 0.8 1.1 1.4 1.2 1.4 1.3 1.0 1.3 1.3
Pack years adult smoking proportion 0.4 0.6 2.0 -1.4 0.7 -0.5 -0.8 0.5 0.3 0.8 -0.2 -1.2 -0.6 -0.9 -0.8 -0.6 -0.8 -0.5 -0.9 -0.6 -0.8 -0.4 -0.7 -1.0 -0.7 -0.7
Impedance of leg (right) 3.1 14.8 17.9 4.2 -3.6 -2.4 3.6 -3.7 3.1 -3.9 4.0 4.0 4.2 3.9 4.0 4.1 3.9 3.5 3.4 4.2 3.9 4.2 4.2 4.0 4.2 4.1
Leg fat-free mass (left) 1.5 7.7 12.5 -3.5 2.5 1.9 -2.9 2.5 -2.3 2.7 -3.5 -3.0 -2.9 -2.8 -2.8 -2.8 -2.7 -2.3 -2.4 -2.8 -2.7 -2.8 -2.9 -2.9 -2.9 -2.8
Trunk fat percentage 1.2 4.8 7.1 1.5 -1.6 -0.8 1.9 -2.3 2.7 -2.2 0.4 2.1 2.4 2.4 2.4 2.5 2.3 2.3 2.2 2.4 2.3 2.4 2.4 2.6 2.4 2.3
Hand grip strength (right) 0.7 1.8 3.5 -1.6 1.6 -0.9 -1.0 1.5 -0.7 1.4 -1.9 -1.4 -1.3 -1.4 -1.4 -1.1 -1.4 -1.0 -1.3 -1.3 -1.4 -1.1 -1.4 -1.3 -1.4 -1.4
Townsend deprivation index at recruitment 2.0 2.8 4.4 1.3 -1.1 -1.2 1.7 -1.9 2.1 -1.7 2.0 1.3 1.9 1.5 1.6 1.9 1.7 1.9 1.3 1.9 1.7 2.0 1.8 1.4 1.8 1.8
Current tobacco smoking 0.3 0.6 4.3 0.4 -1.3 0.1 0.4 -1.2 -0.2 -0.7 2.1 0.7 0.2 0.6 0.7 0.1 0.7 -0.5 1.0 0.3 0.7 -0.1 0.3 0.5 0.4 0.6
Average weekly fortified wine intake 0.3 0.4 0.9 -0.6 0.2 -0.5 -0.6 0.4 -0.8 0.6 0.3 -0.6 -0.6 -0.5 -0.7 -0.8 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -1.0 -0.6 -0.6
Maternal smoking around birth 0.8 1.2 4.7 -1.8 2.2 0.9 -0.1 1.0 0.2 1.2 -1.1 -1.2 -0.4 -1.3 -1.2 -0.3 -1.2 0.9 -1.7 -0.7 -1.2 -0.0 -0.6 -1.3 -0.7 -1.0
Fed-up feelings 0.1 0.2 0.5 -0.5 0.0 -0.3 -0.3 0.5 0.2 0.6 0.3 -0.7 -0.4 -0.6 -0.5 -0.1 -0.5 -0.1 -0.6 -0.4 -0.6 -0.2 -0.4 -0.4 -0.4 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 2.1 -1.0 0.6 0.2 -1.3 1.1 -1.1 1.1 -0.8 -1.2 -1.3 -1.2 -1.2 -1.3 -1.0 -1.4 -0.9 -1.3 -1.1 -1.4 -1.3 -1.3 -1.3 -1.2
Relative age voice broke 0.6 0.9 1.9 0.0 -0.0 0.7 -0.9 0.5 -1.3 0.7 -1.4 -0.9 -1.0 -0.9 -0.9 -1.1 -0.7 -1.4 -0.6 -0.9 -0.7 -1.0 -1.0 -1.3 -1.0 -0.8
Taking other prescription medications 2.0 3.1 5.3 -0.9 1.6 2.3 -1.7 1.8 -1.1 2.1 -1.3 -2.0 -1.8 -2.1 -1.8 -1.7 -2.0 -1.3 -2.0 -1.8 -2.1 -1.5 -1.8 -1.7 -1.9 -2.0
Age when periods started (menarche) 0.5 1.1 2.0 -0.8 1.4 -1.0 -0.8 1.3 0.7 1.2 -1.3 -1.2 -1.0 -1.3 -1.1 -0.7 -1.2 -0.3 -1.3 -1.1 -1.2 -0.8 -0.9 -1.0 -1.0 -1.2
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 1.6 0.2 -0.6 -1.0 -0.1 -0.8 0.3 -0.8 1.2 0.7 0.7 0.7 0.8 0.5 0.8 0.6 0.8 0.7 0.8 0.5 0.7 0.6 0.7 0.7
Heel bone mineral density (BMD) T-score, automated (left) 1.5 3.5 5.8 -1.8 1.0 1.0 -2.0 1.8 -1.9 1.9 -2.2 -2.1 -1.8 -2.0 -2.0 -2.0 -1.9 -1.9 -1.8 -1.8 -1.9 -1.6 -2.0 -2.4 -1.9 -1.8
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.3 -1.1 0.7 0.3 -1.0 0.7 -0.3 0.6 -0.5 -0.5 -0.8 -0.6 -0.6 -0.7 -0.6 -0.4 -0.4 -0.8 -0.6 -0.9 -0.7 -0.5 -0.7 -0.7
Qualifications: CSEs or equivalent 0.2 0.3 1.3 -0.0 0.1 1.1 -1.0 0.2 -0.4 0.1 0.9 -0.1 -0.6 -0.1 -0.1 -0.7 -0.1 -1.1 0.3 -0.4 -0.2 -0.8 -0.6 -0.1 -0.5 -0.3
Serious illness, injury or assault to yourself 0.2 0.3 0.9 -0.3 0.9 0.9 -0.1 0.5 -0.3 0.7 0.7 -0.6 -0.2 -0.6 -0.7 -0.2 -0.6 -0.0 -0.9 -0.3 -0.7 0.1 -0.3 -0.5 -0.4 -0.5
High blood pressure 0.5 1.3 4.4 1.7 -2.1 0.7 0.2 -1.5 -0.0 -1.3 1.1 1.2 0.8 1.2 1.3 0.5 1.4 -0.6 1.7 1.0 1.3 0.4 0.8 1.1 0.9 1.2
Hayfever, allergic rhinitis or eczema 0.5 1.0 1.8 -1.0 1.4 1.2 -0.5 1.1 -0.1 1.1 -0.4 -1.0 -1.0 -1.0 -1.2 -0.8 -1.2 -0.4 -1.1 -1.1 -1.1 -0.9 -1.1 -1.0 -1.1 -1.2
Multivitamins +/- minerals 1.4 1.8 3.1 0.7 -0.6 -0.0 1.4 -1.4 1.0 -1.4 1.2 1.7 1.4 1.7 1.5 1.5 1.4 1.5 1.3 1.3 1.4 1.2 1.5 1.8 1.4 1.3
Stomach or abdominal pain in last month 0.5 0.6 1.4 -0.7 0.9 0.8 -0.7 0.8 -1.2 0.8 -0.3 -1.0 -0.7 -0.7 -0.8 -0.9 -0.8 -0.6 -0.7 -0.7 -0.8 -0.7 -0.7 -0.7 -0.8 -0.8
Supplements: Glucosamine 0.1 0.2 1.2 -0.7 0.4 0.4 -0.0 0.3 -0.1 0.3 -1.1 -0.2 -0.4 -0.2 -0.2 -0.1 -0.3 -0.1 -0.2 -0.4 -0.3 -0.4 -0.4 -0.3 -0.4 -0.4
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 2.1 1.4 -0.5 0.6 1.0 -1.1 0.7 -1.1 0.5 1.0 1.1 1.1 1.0 1.0 1.1 0.8 1.0 1.1 1.1 1.0 1.0 1.1 1.0 1.1
Medication: Atenolol 0.3 0.4 2.3 0.7 -1.4 1.5 -1.1 -0.3 -0.9 -0.4 -0.0 0.1 0.1 0.1 0.4 -0.3 0.4 -1.2 0.6 0.3 0.4 -0.0 0.0 0.0 0.1 0.4
Medication: Levothyroxine sodium 0.1 0.2 0.9 1.0 -0.6 -0.1 -0.1 -0.8 -0.5 -0.3 -0.1 0.4 0.0 0.3 0.4 -0.2 0.4 -0.5 0.5 0.1 0.3 -0.2 0.1 0.2 0.2 0.3
Sitting height 0.1 0.4 1.4 -1.1 0.5 1.0 0.2 0.3 0.9 0.2 -1.0 -0.3 0.6 -0.2 -0.3 0.5 -0.3 1.2 -0.7 0.4 -0.2 1.0 0.3 -0.4 0.2 0.0
Chronic bronchitis/emphysema (father) 0.3 0.3 1.6 1.3 -0.8 -0.7 -0.2 -0.6 -0.9 -0.5 0.3 0.4 -0.2 0.4 0.2 -0.4 0.5 -0.9 0.9 -0.1 0.5 -0.7 -0.1 0.1 0.0 0.3
High blood pressure (mother) 0.0 0.1 0.3 -0.2 0.4 0.0 0.0 0.2 -0.2 0.2 -0.3 -0.2 -0.4 -0.2 -0.2 -0.3 -0.1 -0.3 0.0 -0.4 -0.2 -0.5 -0.3 0.0 -0.3 -0.3
Body mass index (BMI) 0.6 2.5 6.4 -1.8 1.4 0.6 -1.7 1.3 -0.9 1.5 -2.5 -1.7 -1.8 -1.4 -1.4 -1.7 -1.4 -1.6 -1.0 -1.6 -1.5 -1.8 -1.7 -1.4 -1.7 -1.6
Impedance of leg (left) 3.6 17.5 21.7 4.7 -3.9 -2.3 3.9 -4.1 3.4 -4.2 4.1 4.4 4.5 4.3 4.4 4.4 4.3 3.8 3.7 4.5 4.2 4.5 4.5 4.3 4.6 4.5
Leg predicted mass (left) 1.5 8.1 13.1 -3.6 2.5 1.9 -3.0 2.6 -2.3 2.8 -3.5 -3.1 -2.9 -2.8 -2.9 -2.9 -2.8 -2.4 -2.5 -2.9 -2.8 -2.8 -3.0 -3.0 -3.0 -2.9
Trunk fat mass 0.2 0.7 1.9 -0.1 -0.2 0.1 0.5 -0.9 1.4 -0.7 -1.1 0.5 0.8 0.8 0.8 1.0 0.8 1.0 0.7 0.9 0.7 0.9 0.8 1.0 0.8 0.8
Waist circumference 0.0 0.1 1.7 -1.0 -0.2 -0.1 -0.2 -0.2 0.2 0.0 -1.3 -0.3 -0.2 0.0 0.0 -0.2 0.1 -0.3 0.2 -0.1 0.0 -0.2 -0.1 -0.1 -0.1 -0.0
Number of incorrect matches in round 0.3 0.5 2.1 -0.3 0.3 1.4 -1.0 0.4 -1.0 0.6 -0.9 -0.3 -0.6 -0.5 -0.5 -0.7 -0.6 -0.7 -0.5 -0.6 -0.6 -0.6 -0.6 -0.2 -0.6 -0.6
Past tobacco smoking 0.6 1.2 4.1 -0.9 1.9 -1.7 -0.2 1.2 0.3 1.1 -2.0 -1.3 -0.1 -1.0 -1.0 0.1 -1.1 1.1 -1.7 -0.4 -1.1 0.4 -0.3 -1.0 -0.4 -0.8
Alcohol usually taken with meals 2.4 3.9 7.4 -2.2 2.7 1.5 -1.7 2.1 -1.5 2.0 -2.0 -2.0 -1.6 -1.9 -2.2 -1.8 -2.1 -0.6 -2.3 -1.8 -2.1 -1.5 -1.8 -2.6 -1.9 -2.0
Nervous feelings 0.1 0.2 1.0 -0.0 -0.5 -0.7 -0.3 0.1 -0.6 0.1 -0.1 -0.2 -0.5 -0.1 -0.1 -0.6 -0.2 -1.0 0.1 -0.4 -0.2 -0.6 -0.5 -0.4 -0.4 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.7 -0.6 0.1 -0.5 -0.3 0.1 0.0 0.3 0.9 -0.3 -0.5 -0.4 -0.3 -0.3 -0.3 -0.3 -0.2 -0.5 -0.3 -0.6 -0.4 -0.2 -0.4 -0.4
Hearing difficulty/problems with background noise 1.0 1.6 3.0 -1.7 1.7 0.6 -1.0 1.2 -0.4 1.5 -1.5 -1.4 -1.3 -1.5 -1.4 -1.0 -1.5 -0.5 -1.4 -1.3 -1.4 -1.0 -1.3 -1.1 -1.3 -1.4
Hair/balding pattern: Pattern 2 0.4 0.5 1.8 -0.8 0.5 -1.3 -0.9 0.5 -0.6 0.7 0.7 -0.7 -0.8 -0.7 -0.8 -0.7 -0.6 -0.4 -0.6 -0.8 -0.7 -0.8 -0.7 -0.6 -0.7 -0.7
Had menopause 0.1 0.2 0.6 -0.5 0.3 0.2 -0.8 0.6 -0.3 0.4 -0.0 -0.6 -0.4 -0.6 -0.2 -0.3 -0.4 -0.4 -0.4 -0.3 -0.4 -0.2 -0.4 -0.3 -0.4 -0.3
Had other major operations 0.2 0.3 0.7 0.7 -0.8 0.8 0.4 -0.4 -0.0 -0.5 0.3 0.4 0.6 0.5 0.4 0.3 0.6 0.0 0.5 0.7 0.6 0.6 0.5 0.2 0.5 0.6
Forced vital capacity (FVC) 0.1 0.2 0.8 -0.9 -0.6 -0.4 -0.3 0.5 -0.5 0.4 0.4 -0.4 -0.5 -0.4 -0.5 -0.3 -0.4 -0.9 -0.2 -0.5 -0.4 -0.5 -0.5 -0.4 -0.5 -0.4
Heel bone mineral density (BMD) T-score, automated (right) 1.8 4.1 5.9 -1.5 1.7 1.2 -2.1 2.0 -1.7 2.1 -2.1 -2.2 -2.1 -2.2 -2.2 -2.1 -2.1 -1.8 -2.1 -2.1 -2.1 -1.8 -2.1 -2.4 -2.1 -2.1
Ever unenthusiastic/disinterested for a whole week 1.9 2.4 3.7 -1.8 0.8 0.5 -1.2 1.7 -1.0 1.6 -0.2 -1.7 -1.9 -1.5 -1.6 -1.7 -1.5 -1.9 -1.3 -1.8 -1.6 -1.8 -1.8 -1.5 -1.8 -1.7
Qualifications: None of the above 0.2 0.3 1.7 -1.3 -0.2 0.7 -0.2 0.6 -0.0 0.5 0.6 -0.5 -0.6 -0.5 -0.6 -0.5 -0.5 -0.6 -0.4 -0.6 -0.5 -0.5 -0.6 -0.6 -0.6 -0.5
Financial difficulties in last 2 years 0.5 0.7 1.5 -0.8 0.6 0.3 -0.9 0.7 -0.7 0.7 0.0 -0.8 -1.1 -0.8 -0.6 -1.0 -0.8 -1.2 -0.3 -1.0 -0.8 -1.2 -1.0 -0.3 -1.0 -0.9
Mouth/teeth dental problems 0.1 0.2 0.7 0.2 0.8 0.8 0.3 0.7 0.1 0.3 -0.5 -0.3 0.1 -0.3 -0.4 0.0 -0.4 0.6 -0.7 -0.0 -0.4 0.3 -0.0 -0.5 -0.1 -0.2
Heart attack 1.6 2.0 8.1 1.7 -0.6 -1.2 2.2 -0.9 2.9 -1.0 0.2 1.1 1.5 1.0 1.2 1.9 1.0 1.7 0.5 1.4 1.0 1.8 1.5 1.1 1.5 1.2
Allergy 0.1 0.3 3.5 0.5 -0.7 -1.9 -0.0 -0.3 0.2 -0.3 1.1 0.1 0.3 0.1 0.3 0.2 0.3 -0.1 0.2 0.3 0.3 0.4 0.3 0.1 0.3 0.4
Pain all over the body in last month 0.5 0.6 3.2 0.3 -1.7 -0.7 -0.3 -0.7 -1.2 -0.5 0.2 0.5 -0.4 0.4 0.4 -0.5 0.5 -1.8 1.2 -0.2 0.6 -0.9 -0.2 0.4 -0.1 0.3
Diabetes (self-reported) 0.6 0.9 2.4 0.2 -0.1 -0.1 1.1 -0.7 1.3 -0.8 0.6 0.5 1.2 0.7 0.9 1.2 0.8 1.5 0.6 1.2 0.8 1.3 1.1 0.7 1.0 0.9
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 2.3 -0.4 0.3 0.7 -1.2 0.6 -1.5 0.8 -0.2 -0.6 -1.3 -0.7 -0.9 -1.3 -0.8 -1.4 -0.3 -1.2 -0.8 -1.5 -1.1 -0.6 -1.1 -1.0
Medication: Ramipril 0.1 0.1 1.2 1.1 -0.3 -0.4 -0.0 -0.4 0.4 -0.3 -0.4 0.5 0.1 0.2 0.5 0.1 0.4 -0.4 0.5 0.1 0.3 -0.1 0.1 0.3 0.2 0.3
Medication: Simvastatin 0.4 0.5 1.4 1.2 -0.9 0.8 0.6 -0.6 1.0 -0.8 -0.9 0.8 0.5 0.8 0.8 0.4 0.8 0.1 0.9 0.6 0.8 0.3 0.5 0.5 0.6 0.7
Fluid intelligence score 0.5 1.0 3.6 1.0 -0.2 0.2 0.5 -0.8 0.6 -0.8 1.9 0.7 1.4 0.5 0.8 1.3 0.8 1.7 0.3 1.2 0.8 1.5 1.2 0.6 1.1 1.0
Illnesses of siblings 0.1 0.1 1.6 0.2 0.2 -0.3 0.1 0.0 0.8 -0.2 -1.3 0.2 0.3 0.2 0.1 0.3 0.2 0.5 0.0 0.2 0.2 0.2 0.2 -0.1 0.2 0.2
Neuroticism score 0.2 0.4 1.2 -0.7 0.3 -1.1 -0.1 0.5 0.4 0.7 -0.1 -0.8 -0.6 -0.7 -0.6 -0.3 -0.7 -0.4 -0.8 -0.6 -0.7 -0.4 -0.6 -0.7 -0.6 -0.7
Weight 0.7 3.4 9.1 -2.5 1.6 1.0 -2.0 1.5 -1.1 1.8 -3.0 -2.1 -1.9 -1.8 -1.8 -1.8 -1.8 -1.5 -1.5 -1.8 -1.8 -1.8 -1.9 -1.8 -1.9 -1.9
Impedance of arm (right) 4.9 22.9 30.1 4.0 -3.8 -2.6 5.2 -4.3 5.0 -4.6 5.2 4.7 5.3 4.6 4.8 5.5 4.7 5.2 3.8 5.2 4.6 5.5 5.3 4.9 5.3 4.9
Arm fat percentage (right) 0.2 0.9 3.4 0.2 -0.3 -0.8 0.9 -0.9 1.9 -0.8 -0.7 0.7 0.9 0.9 1.0 1.2 0.9 1.2 0.9 1.0 0.9 1.0 1.0 1.1 1.0 0.9
Trunk fat-free mass 3.7 21.4 25.2 -5.0 4.0 2.8 -5.0 4.3 -4.1 4.7 -4.7 -4.9 -4.8 -4.8 -4.8 -4.8 -4.7 -4.0 -4.3 -4.8 -4.7 -4.7 -4.9 -5.0 -5.0 -4.8
Hip circumference 0.0 0.2 1.9 -1.4 0.4 0.2 -0.3 0.1 0.7 0.3 -1.0 -0.6 -0.1 -0.2 -0.2 -0.0 -0.2 0.3 -0.3 -0.1 -0.3 0.1 -0.2 -0.4 -0.2 -0.2
Time employed in main current job 1.5 1.7 3.6 1.9 -1.6 -0.9 0.8 -1.4 -0.3 -1.6 0.2 1.6 1.0 1.6 1.5 0.8 1.6 0.3 1.9 1.1 1.6 0.5 1.1 1.5 1.2 1.4
Alcohol intake versus 10 years previously 0.2 0.3 0.8 -0.8 -0.1 0.7 -0.6 0.6 -0.5 0.5 0.6 -0.5 -0.7 -0.4 -0.4 -0.6 -0.4 -0.9 -0.3 -0.6 -0.4 -0.7 -0.6 -0.6 -0.6 -0.5
Father’s age at death 1.6 2.2 4.6 -1.1 2.1 1.0 -0.8 1.8 -0.3 1.7 -1.5 -1.4 -1.3 -1.7 -1.8 -1.2 -1.7 -0.5 -1.8 -1.5 -1.7 -1.1 -1.4 -1.8 -1.5 -1.6
Worrier / anxious feelings 0.1 0.2 0.8 -0.9 0.3 -0.3 -0.2 0.3 -0.2 0.4 0.4 -0.4 -0.5 -0.4 -0.3 -0.3 -0.3 -0.5 -0.2 -0.4 -0.4 -0.5 -0.5 -0.1 -0.5 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.0 0.0 0.3 -0.0 -0.2 -0.5 0.4 -0.1 0.6 0.0 -0.2 -0.3 -0.1 -0.0 0.0 0.2 0.0 -0.2 0.1 0.0 0.0 0.0 -0.0 0.3 0.0 0.0
Falls in the last year 2.1 2.9 6.3 -2.1 1.0 0.8 -1.7 1.4 -2.5 1.5 -1.9 -1.9 -1.6 -1.6 -1.7 -1.9 -1.5 -1.9 -1.4 -1.6 -1.5 -1.6 -1.7 -1.9 -1.7 -1.5
Hair/balding pattern: Pattern 3 0.2 0.3 3.7 0.3 -0.5 1.9 -0.4 -0.2 -0.8 -0.2 0.6 0.5 -0.2 0.3 0.2 -0.4 0.2 -0.7 0.5 -0.2 0.2 -0.6 -0.2 0.2 -0.1 0.0
Number of live births 2.9 4.1 6.0 2.0 -2.5 -1.9 1.6 -2.3 1.8 -2.2 1.0 1.8 2.0 1.9 2.2 2.1 2.2 1.1 2.3 2.1 2.2 1.9 2.0 2.3 2.1 2.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 2.0 -1.3 -0.2 -0.6 -1.0 1.1 -1.1 0.8 -0.2 -1.0 -1.0 -0.8 -0.9 -0.9 -0.8 -1.4 -0.6 -0.9 -0.8 -1.1 -1.0 -0.7 -1.0 -0.9
Pulse rate 0.6 0.9 2.6 -1.1 1.0 -0.1 -0.6 0.6 -1.6 1.0 -0.8 -1.0 -1.1 -0.8 -0.9 -1.1 -1.0 -1.0 -0.7 -1.0 -0.9 -1.1 -1.1 -0.8 -1.1 -1.0
Happiness 0.5 0.6 2.7 -1.6 1.3 -0.7 0.7 0.8 0.8 0.7 -0.1 -0.7 0.1 -0.7 -0.6 0.4 -0.6 1.4 -1.2 -0.1 -0.7 0.5 -0.0 -0.8 -0.1 -0.5
Noisy workplace 0.1 0.1 1.9 -0.2 -0.0 0.5 0.6 -0.2 0.2 -0.0 1.4 0.0 0.2 0.0 -0.1 0.1 0.0 0.3 -0.1 0.1 0.0 0.3 0.1 -0.1 0.1 0.1
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.5 0.2 0.7 -0.3 -0.7 0.7 -1.0 0.6 -0.6 -0.2 -0.9 -0.4 -0.5 -1.0 -0.5 -0.8 -0.3 -0.9 -0.6 -1.2 -0.8 -0.3 -0.8 -0.7
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 2.5 -1.6 1.0 -0.3 -1.1 1.4 -1.0 1.2 -0.3 -1.4 -1.2 -1.1 -1.2 -1.3 -1.3 -1.1 -1.1 -1.2 -1.2 -1.1 -1.3 -1.1 -1.3 -1.2
Mouth/teeth dental problems: Dentures 0.0 0.0 0.6 -0.4 -0.0 0.8 -0.5 -0.1 -0.0 0.1 -0.1 0.1 -0.1 -0.1 0.1 0.0 -0.1 0.1 -0.0 -0.1 -0.1 -0.1 -0.0 0.0 -0.0 -0.1
Asthma 0.2 0.4 2.1 0.7 -0.4 1.5 -0.1 -0.5 -1.1 -0.5 -0.0 0.8 -0.1 0.8 0.5 -0.3 0.5 -0.2 0.9 0.0 0.5 -0.6 0.1 0.7 0.1 0.2
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 3.5 0.5 0.4 -0.8 0.5 0.0 1.2 -0.1 -1.9 0.1 0.6 0.0 0.1 0.8 0.0 1.2 -0.2 0.4 0.1 0.8 0.5 0.1 0.4 0.2
Medication: Cholesterol lowering 0.1 0.1 1.2 0.9 -0.2 1.1 0.4 -0.1 0.8 0.0 0.3 0.0 0.0 -0.1 0.1 0.2 -0.0 0.0 -0.1 0.1 -0.0 0.2 0.0 0.0 0.0 0.0
Depression (self-reported) 0.7 0.9 2.0 0.5 -1.4 -0.1 1.0 -1.0 0.7 -0.9 1.4 0.9 1.0 0.9 1.0 1.1 0.9 0.7 0.8 1.0 0.9 1.0 0.9 0.7 1.0 1.0
Medication: Lansoprazole 0.5 0.5 4.0 -0.1 -0.1 1.4 -1.3 -0.2 -2.0 0.1 0.5 -0.4 -0.6 -0.3 -0.2 -0.9 -0.0 -0.9 0.2 -0.5 -0.1 -1.0 -0.5 -0.4 -0.5 -0.3
Prospective memory result 0.5 0.6 7.6 -0.3 0.2 2.8 -0.3 0.5 -0.1 0.7 -0.7 -0.5 -0.5 -0.6 -0.7 -0.5 -0.6 -0.8 -0.7 -0.5 -0.6 -0.3 -0.6 -0.7 -0.5 -0.5
Lung cancer (father) 1.4 1.7 2.5 1.0 -1.0 -1.1 1.1 -1.5 1.3 -1.3 1.2 1.3 1.4 1.3 1.2 1.5 1.3 1.6 1.2 1.3 1.3 1.3 1.4 1.2 1.4 1.3
Illnesses of mother 0.1 0.2 0.8 0.3 -0.0 0.3 0.6 0.2 0.9 0.0 -0.9 0.1 0.4 0.1 0.1 0.6 -0.1 0.6 -0.3 0.3 -0.0 0.8 0.3 0.2 0.3 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 1.5 0.5 -1.2 -1.0 0.4 -0.7 -0.2 -1.0 0.3 1.0 0.7 1.0 0.9 0.7 1.0 0.2 1.2 0.8 1.1 0.3 0.7 0.9 0.8 0.9
Pulse wave Arterial Stiffness index 1.7 2.0 5.2 -1.7 0.0 1.0 -2.3 0.9 -1.7 1.1 -0.9 -1.2 -1.7 -1.1 -1.1 -1.7 -1.1 -2.2 -0.5 -1.4 -1.1 -1.8 -1.6 -1.2 -1.6 -1.3
Impedance of arm (left) 6.0 28.0 36.0 4.6 -4.2 -3.0 5.5 -4.9 5.2 -5.2 5.2 5.4 5.9 5.3 5.4 6.0 5.2 5.7 4.4 5.8 5.2 6.0 5.9 5.5 5.8 5.5
Arm fat mass (right) 0.2 0.8 3.8 -1.3 1.0 0.4 -1.1 0.7 0.0 0.8 -2.0 -1.1 -0.9 -0.8 -0.8 -0.7 -0.8 -0.5 -0.6 -0.8 -0.8 -0.8 -0.9 -0.6 -0.9 -0.9
Trunk predicted mass 3.7 21.2 24.8 -5.0 4.1 2.8 -5.0 4.3 -4.2 4.7 -4.6 -4.9 -4.8 -4.8 -4.8 -4.8 -4.7 -4.0 -4.3 -4.8 -4.7 -4.7 -4.9 -5.0 -4.9 -4.8
Standing height 0.1 1.0 4.0 -2.0 0.9 1.1 -1.1 0.8 -0.5 1.0 -1.2 -1.2 -0.6 -1.1 -1.1 -0.6 -1.1 0.0 -1.3 -0.7 -1.0 -0.3 -0.7 -1.2 -0.8 -0.9
Length of working week for main job 0.9 1.0 2.9 0.3 0.2 -1.4 0.9 -0.8 1.6 -0.6 0.8 0.9 1.0 0.8 0.8 1.3 0.7 1.7 0.4 0.9 0.7 1.1 1.0 1.0 1.0 0.7
Exposure to tobacco smoke at home 0.4 0.4 5.6 0.7 -0.4 -2.4 0.3 -0.6 0.7 -0.5 0.5 0.4 0.2 0.5 0.5 0.4 0.5 0.0 0.6 0.3 0.5 0.2 0.3 0.7 0.3 0.4
Breastfed as a baby 0.4 0.5 1.2 0.8 -1.1 1.1 0.8 -0.7 0.6 -0.7 -0.1 1.0 0.5 0.8 0.7 0.6 0.8 -0.0 0.9 0.6 0.7 0.4 0.5 0.6 0.6 0.7
Tense / ‘highly strung’ 0.1 0.2 1.0 0.4 -0.6 -0.4 -0.4 0.1 -0.2 0.3 0.5 -0.2 -0.5 -0.3 -0.2 -0.4 -0.3 -1.0 -0.1 -0.4 -0.3 -0.4 -0.5 -0.2 -0.4 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 1.8 -1.0 0.6 0.6 -1.1 1.3 -0.9 1.2 -0.1 -1.1 -1.4 -1.3 -1.2 -1.2 -1.1 -1.3 -1.0 -1.3 -1.2 -1.3 -1.3 -1.3 -1.3 -1.2
Hair/balding pattern: Pattern 4 0.0 0.1 0.8 -0.1 -0.3 -0.0 0.3 -0.3 0.5 -0.1 0.9 -0.1 0.1 0.2 0.1 0.2 0.0 -0.3 0.1 0.3 0.0 0.4 0.1 0.4 0.1 0.2
Birth weight of first child 0.1 0.3 2.3 -0.2 0.4 -1.5 -0.5 0.3 -0.0 0.4 0.6 -0.6 -0.3 -0.6 -0.5 -0.2 -0.4 0.2 -0.5 -0.4 -0.4 -0.3 -0.3 -0.5 -0.3 -0.4
Peak expiratory flow (PEF) 0.2 0.4 1.2 -0.5 -0.5 -0.3 -0.6 0.8 -0.6 0.5 -0.7 -0.7 -0.8 -0.5 -0.5 -0.6 -0.5 -1.1 -0.2 -0.6 -0.5 -0.8 -0.7 -0.3 -0.7 -0.5
Pulse wave reflection index 1.8 2.2 5.8 -2.3 0.1 1.5 -2.4 1.0 -1.4 1.1 -0.7 -1.2 -1.7 -1.2 -1.2 -1.7 -1.2 -2.1 -0.7 -1.5 -1.2 -1.8 -1.7 -1.2 -1.6 -1.4
Ever highly irritable/argumentative for 2 days 0.3 0.4 2.0 -0.3 -0.6 -0.8 -0.7 0.5 -0.4 0.5 -0.1 -0.4 -0.8 -0.4 -0.4 -0.7 -0.5 -1.4 -0.3 -0.7 -0.5 -0.8 -0.8 -0.5 -0.7 -0.5
Loud music exposure frequency 0.1 0.1 1.0 -0.1 -0.7 1.0 -0.0 -0.1 0.3 -0.1 0.7 0.1 -0.0 0.2 0.1 0.1 0.1 -0.3 0.2 0.1 0.1 0.0 -0.1 0.0 -0.0 0.1
Qualifications: O levels/GCSEs or equivalent 1.1 1.7 8.0 1.4 -1.5 -2.8 0.9 -1.2 0.9 -1.2 0.6 1.3 1.1 1.3 1.3 1.2 1.3 0.7 1.2 1.2 1.2 1.0 1.2 1.5 1.2 1.2
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 2.1 1.3 -1.4 -1.4 0.8 -1.4 1.0 -1.1 0.6 1.0 0.8 1.2 1.1 0.9 1.2 0.2 1.4 1.0 1.2 0.7 0.9 1.4 1.0 1.1
Blood clot in the leg (DVT) 0.1 0.1 0.8 -0.3 0.3 -0.9 0.3 0.1 0.4 0.0 -0.7 0.0 0.0 0.0 -0.1 0.2 0.1 0.3 0.0 0.0 -0.0 0.1 0.1 0.1 0.1 -0.0
Medication: Paracetamol 0.9 1.5 2.8 -1.1 1.3 0.9 -1.2 1.0 -0.4 1.1 -1.5 -1.0 -1.5 -1.1 -1.1 -1.5 -1.1 -1.3 -0.7 -1.4 -1.1 -1.7 -1.4 -0.9 -1.4 -1.3
Headache pain in last month 2.0 3.5 7.2 -2.7 2.4 1.3 -1.7 2.0 -0.3 2.2 -1.0 -2.0 -1.7 -2.1 -2.1 -1.4 -2.2 -0.4 -2.4 -1.8 -2.1 -1.4 -1.8 -2.1 -1.9 -2.1
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.8 -0.1 -0.4 -0.8 -0.3 0.1 -0.9 -0.1 -0.5 0.3 -0.3 0.1 -0.0 -0.4 0.1 -0.7 0.4 -0.2 0.1 -0.6 -0.2 0.3 -0.1 -0.0
Glaucoma (self-reported) 0.3 0.3 0.7 -0.1 0.5 0.5 -0.4 0.7 -0.4 0.6 0.7 -0.6 -0.5 -0.7 -0.7 -0.5 -0.6 -0.3 -0.8 -0.6 -0.7 -0.5 -0.5 -0.8 -0.5 -0.6
Gout (self-reported) 2.4 3.3 9.8 2.1 0.2 -0.8 2.3 -1.6 3.1 -1.4 0.4 1.3 2.2 1.3 1.5 2.3 1.5 3.0 0.8 1.9 1.4 2.4 2.1 1.4 2.0 1.6
Hypothyroidism/myxoedema (self-reported) 0.0 0.1 0.5 0.5 -0.2 -0.7 0.1 -0.5 0.1 -0.2 -0.3 0.1 0.0 0.0 0.1 -0.0 0.2 -0.1 0.1 0.1 0.1 0.0 0.1 -0.0 0.2 0.2
Medication: Amlodipine 1.0 1.4 2.3 0.9 -1.5 -1.0 1.3 -1.4 1.2 -1.3 1.0 0.9 1.0 1.2 1.4 1.1 1.3 0.5 1.5 1.1 1.3 0.9 1.1 1.2 1.1 1.3
Medication: Ventolin 100micrograms inhaler 0.1 0.2 1.7 0.6 0.3 -1.3 0.8 0.0 0.5 0.1 0.8 -0.0 0.2 0.1 0.1 0.3 -0.1 0.6 -0.3 0.1 -0.1 0.3 0.1 0.1 0.1 -0.0
Birth weight 0.2 0.4 1.6 -0.5 0.3 1.2 -1.1 0.6 -1.3 0.5 0.3 -0.4 -0.5 -0.5 -0.5 -0.6 -0.6 -0.4 -0.5 -0.5 -0.5 -0.5 -0.5 -0.4 -0.6 -0.5
Chronic bronchitis/emphysema (mother) 2.0 2.3 5.1 -0.9 0.9 2.3 -1.8 1.2 -1.4 1.5 -0.2 -1.4 -1.7 -1.5 -1.6 -1.6 -1.5 -1.7 -1.3 -1.6 -1.5 -1.6 -1.7 -1.4 -1.7 -1.6
High blood pressure (siblings) 0.6 0.9 2.7 -1.3 0.4 0.8 -1.2 0.5 -1.7 0.8 -0.4 -1.0 -1.1 -0.8 -0.8 -1.2 -0.8 -1.4 -0.4 -0.9 -0.7 -1.1 -1.0 -0.5 -1.0 -0.8
Forced vital capacity (FVC), Best measure 0.3 1.3 3.2 1.0 -1.8 -0.8 0.8 -1.1 -0.0 -1.4 0.8 1.4 0.9 1.3 1.2 0.9 1.3 0.2 1.6 1.0 1.4 0.5 1.0 1.3 1.0 1.2
Body fat percentage 1.0 3.9 6.2 1.3 -1.3 -0.9 1.8 -2.1 2.5 -2.0 -0.0 1.9 2.1 2.1 2.2 2.2 2.1 2.0 2.0 2.2 2.0 2.1 2.1 2.4 2.1 2.1
Leg fat percentage (right) 0.1 0.4 1.1 0.4 -0.4 -0.6 0.5 -0.8 1.1 -0.6 -0.5 0.5 0.6 0.7 0.8 0.7 0.7 0.5 0.7 0.7 0.6 0.6 0.6 0.9 0.7 0.6
Arm fat-free mass (right) 2.2 11.1 15.3 -3.6 2.9 2.3 -3.9 2.8 -3.4 3.2 -3.9 -3.5 -3.5 -3.3 -3.4 -3.6 -3.2 -3.1 -2.7 -3.4 -3.2 -3.5 -3.5 -3.5 -3.5 -3.4
Exposure to tobacco smoke outside home 0.3 0.4 1.0 0.9 -0.3 0.6 -0.0 -0.9 -0.9 -0.7 0.7 0.8 0.3 0.9 0.7 0.1 0.7 -0.1 1.0 0.5 0.7 0.1 0.4 1.0 0.5 0.6
Comparative body size at age 10 1.5 4.1 7.7 -1.1 1.1 0.7 -2.3 1.8 -2.2 2.0 -2.2 -2.1 -2.4 -1.9 -2.0 -2.3 -2.0 -2.8 -1.5 -2.2 -2.0 -2.4 -2.3 -1.7 -2.2 -2.0
Number of full brothers 0.2 0.2 0.8 0.5 -0.6 0.5 -0.2 -0.5 -0.1 -0.6 0.9 0.6 0.2 0.4 0.4 0.0 0.6 -0.1 0.7 0.2 0.5 -0.3 0.3 0.3 0.3 0.4
Worry too long after embarrassment 0.4 0.7 4.5 0.2 -0.6 -2.1 0.9 -0.7 0.7 -0.7 -0.3 0.7 0.7 0.7 0.8 0.8 0.7 0.6 0.7 0.7 0.7 0.7 0.7 0.9 0.8 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 1.5 -1.0 -0.1 0.8 -1.1 0.9 -1.0 0.9 -0.0 -1.1 -0.9 -1.0 -0.7 -0.8 -0.8 -1.2 -0.8 -0.8 -0.9 -0.6 -0.9 -0.8 -0.9 -0.8
Wheeze or whistling in the chest in last year 1.1 1.9 2.9 -1.6 1.2 0.4 -1.0 1.7 -0.5 1.6 -0.7 -1.3 -1.5 -1.3 -1.6 -1.2 -1.6 -0.8 -1.6 -1.6 -1.6 -1.4 -1.5 -1.6 -1.5 -1.6
Number of children fathered 0.4 0.5 3.0 0.2 0.7 0.3 -0.2 0.8 -0.5 0.7 -1.7 -0.4 -0.6 -0.6 -0.8 -0.6 -0.7 -0.3 -0.7 -0.7 -0.7 -0.6 -0.6 -0.9 -0.6 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 0.6 -0.5 0.7 0.2 -0.5 0.5 0.3 0.3 -0.5 -0.5 -0.1 -0.5 -0.4 -0.1 -0.4 0.2 -0.5 -0.2 -0.4 -0.1 -0.2 -0.4 -0.2 -0.3
Age at first live birth 0.3 0.5 1.7 -0.1 1.3 -0.4 -0.3 1.1 0.4 0.7 -1.3 -0.6 -0.5 -0.7 -0.8 -0.3 -0.7 0.2 -0.9 -0.6 -0.8 -0.4 -0.5 -0.5 -0.6 -0.7
Pulse wave peak to peak time 1.3 1.5 4.6 1.5 0.2 -0.9 2.0 -0.7 1.5 -0.8 0.6 1.0 1.5 0.8 0.9 1.5 0.9 2.1 0.2 1.2 0.8 1.7 1.4 0.9 1.4 1.0
Health satisfaction 3.0 3.9 5.4 -2.3 2.3 0.3 -1.6 2.0 -1.8 2.1 -1.9 -2.2 -1.9 -2.0 -2.1 -1.9 -2.0 -1.2 -2.0 -2.0 -2.1 -1.9 -2.0 -2.2 -2.1 -2.1
Shortness of breath walking on level ground 0.1 0.1 1.0 0.8 -0.5 -0.3 0.0 -0.1 -0.4 -0.1 -1.0 0.2 -0.1 0.2 0.1 -0.2 0.1 -0.6 0.2 0.0 0.1 -0.1 -0.1 0.2 -0.0 0.1
Qualifications: College or University degree 0.3 0.8 2.3 -0.4 1.0 0.0 -1.1 0.9 -1.1 0.8 -1.5 -0.9 -1.0 -0.8 -0.9 -1.0 -0.8 -0.9 -0.6 -1.0 -0.8 -1.1 -1.0 -0.5 -1.0 -0.9
Eye problems/disorders: None of the above 0.6 0.7 1.9 1.2 -1.4 -0.4 -0.0 -0.8 -1.0 -0.9 0.1 1.0 0.2 1.0 1.0 -0.0 0.9 -0.9 1.4 0.4 0.9 -0.1 0.3 1.1 0.4 0.7
Mouth/teeth dental problems: Loose teeth 1.3 1.5 2.0 0.9 -0.7 -1.1 1.1 -1.4 0.4 -1.3 0.9 1.2 1.4 1.3 1.4 1.2 1.4 1.2 1.2 1.4 1.3 1.3 1.4 1.2 1.4 1.4
Emphysema/chronic bronchitis 0.4 0.4 1.3 -0.2 -0.0 -0.5 1.0 -0.8 0.3 -0.6 0.2 0.5 0.8 0.6 0.7 0.7 0.7 1.1 0.4 0.7 0.7 0.7 0.8 0.4 0.7 0.6
Medication for pain relief, constipation, heartburn 0.3 0.5 3.1 0.1 -0.7 -1.6 0.5 -0.4 -0.0 -0.5 1.8 0.4 0.6 0.5 0.4 0.6 0.5 0.4 0.3 0.6 0.5 0.7 0.6 0.5 0.6 0.6
Neck or shoulder pain in last month 5.7 8.1 10.4 -2.7 3.2 2.4 -3.1 2.8 -2.9 3.0 -1.7 -2.9 -2.8 -3.0 -3.0 -3.0 -2.9 -1.9 -2.9 -2.9 -3.0 -2.7 -2.9 -3.2 -2.9 -3.0
Medication: Blood pressure 0.1 0.2 2.7 0.1 0.2 1.6 -0.1 -0.3 0.3 -0.0 1.0 -0.3 0.2 -0.1 0.0 0.2 0.1 0.3 -0.1 0.3 0.0 0.4 0.2 -0.2 0.1 0.1
Angina (self-reported) 0.1 0.2 1.3 1.0 -1.1 0.3 -0.3 -0.2 -0.4 -0.3 0.3 0.0 -0.0 0.1 0.3 -0.3 0.3 -0.9 0.4 0.1 0.3 -0.2 -0.0 -0.3 0.0 0.3
Migraine (self-reported) 0.2 0.2 2.0 -0.0 0.6 1.4 0.3 -0.0 -0.1 -0.2 -1.1 0.1 0.4 -0.1 0.3 0.3 0.2 0.9 0.0 0.3 0.2 0.4 0.4 0.0 0.3 0.2
Medication: Ibuprofen 0.7 0.8 5.3 -0.3 1.7 -0.6 -0.3 1.0 0.5 0.8 -2.3 -0.8 -0.3 -0.9 -0.8 -0.0 -0.9 0.8 -1.1 -0.5 -0.8 -0.0 -0.4 -0.8 -0.5 -0.7
Medication: Allopurinol 0.2 0.2 1.1 0.7 1.1 -0.5 0.3 -0.0 0.6 0.4 -0.6 -0.4 0.1 -0.5 -0.3 0.2 -0.2 0.7 -0.7 -0.0 -0.4 0.3 0.1 -0.2 0.0 -0.2
Medication: Omeprazole 2.8 3.3 4.3 -1.3 1.8 1.3 -1.5 2.0 -1.7 2.0 -2.0 -2.0 -1.7 -2.0 -2.0 -1.8 -2.0 -1.5 -2.0 -1.8 -2.0 -1.4 -1.8 -2.1 -1.9 -1.9
Medication: Seretide 50 evohaler 0.1 0.1 2.1 0.1 -0.1 1.5 0.2 -0.1 -0.4 -0.0 -0.4 0.1 0.1 -0.0 -0.1 -0.0 -0.1 0.2 -0.1 0.0 0.0 0.1 0.0 -0.1 0.0 -0.0
Mean time to correctly identify matches 0.3 0.7 3.4 0.2 -0.8 0.3 0.2 -1.2 0.5 -0.6 1.9 0.4 0.9 0.5 0.7 1.0 0.6 0.9 0.4 0.9 0.6 1.1 0.9 0.8 0.8 0.8
Heart disease (mother) 0.2 0.2 0.6 0.3 -0.4 -0.3 0.7 -0.8 0.3 -0.4 -0.3 0.5 0.6 0.5 0.5 0.5 0.5 0.7 0.3 0.5 0.4 0.5 0.6 0.2 0.5 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 4.8 5.8 8.4 -1.0 1.5 0.2 -2.5 2.0 -2.6 2.5 -1.9 -2.6 -2.8 -2.5 -2.6 -2.8 -2.5 -2.9 -2.1 -2.7 -2.5 -2.7 -2.8 -2.4 -2.7 -2.6
Whole body fat mass 0.1 0.3 2.5 -0.5 0.2 0.2 0.1 -0.4 1.0 -0.2 -1.6 -0.0 0.3 0.3 0.3 0.5 0.3 0.6 0.3 0.4 0.3 0.5 0.3 0.4 0.3 0.3
Leg fat mass (right) 0.1 0.3 3.1 -0.7 0.5 0.4 -0.5 0.2 0.2 0.4 -1.8 -0.5 -0.4 -0.2 -0.2 -0.3 -0.3 -0.3 -0.1 -0.3 -0.3 -0.3 -0.4 -0.1 -0.4 -0.4
Arm predicted mass (right) 2.0 10.4 16.7 -3.4 2.8 1.8 -3.8 2.7 -3.3 3.1 -4.1 -3.4 -3.4 -3.2 -3.2 -3.5 -3.1 -3.0 -2.6 -3.3 -3.1 -3.4 -3.4 -3.3 -3.4 -3.2
Pulse rate, automated reading 0.1 0.2 1.5 -1.2 0.9 -0.5 0.6 0.1 0.6 0.4 -0.2 -0.4 0.1 -0.2 -0.2 0.3 -0.4 0.8 -0.6 0.0 -0.4 0.5 0.0 -0.1 -0.0 -0.2
Alcohol intake frequency. 0.2 0.5 1.9 -0.4 0.2 -1.4 -0.6 0.5 -0.6 0.6 -0.8 -1.0 -0.6 -0.8 -0.6 -0.6 -0.6 -0.7 -0.6 -0.6 -0.6 -0.6 -0.7 -1.0 -0.6 -0.6
Comparative height size at age 10 0.1 0.3 1.5 -1.2 -0.1 1.1 0.6 -0.4 0.3 -0.1 0.3 0.0 0.6 0.0 0.1 0.7 0.1 1.0 -0.2 0.5 0.1 0.9 0.5 0.1 0.4 0.3
Number of full sisters 0.3 0.4 5.1 0.1 0.3 -0.7 -0.2 0.7 0.0 0.2 -2.3 -0.4 -0.6 -0.4 -0.3 -0.3 -0.3 -0.6 -0.0 -0.5 -0.2 -0.7 -0.5 -0.2 -0.4 -0.4
Suffer from ‘nerves’ 0.8 1.3 3.0 1.0 -1.7 -0.1 1.3 -1.3 0.8 -1.3 1.2 1.3 1.0 1.3 1.3 1.0 1.3 0.5 1.4 1.1 1.3 0.8 1.1 0.9 1.1 1.2
Overall health rating 1.0 2.2 7.2 -0.9 1.0 0.7 -2.1 0.9 -2.7 1.2 -0.5 -1.6 -1.6 -1.5 -1.3 -1.9 -1.1 -1.8 -0.8 -1.5 -1.2 -1.9 -1.6 -1.5 -1.6 -1.4
Chest pain or discomfort 0.2 0.3 2.2 0.4 -0.3 1.5 -0.2 0.1 -1.3 -0.0 0.4 0.2 -0.3 0.0 0.0 -0.5 0.1 -0.7 0.3 -0.3 0.0 -0.6 -0.2 0.1 -0.2 -0.1
Had major operations 1.5 1.7 4.0 -0.5 1.5 1.4 -1.2 1.2 -0.8 1.5 -2.0 -1.4 -1.2 -1.5 -1.4 -1.2 -1.5 -0.6 -1.6 -1.3 -1.5 -0.9 -1.2 -1.4 -1.3 -1.4
Age at last live birth 0.4 0.5 3.1 0.1 1.1 -1.4 0.9 0.7 1.8 0.3 -0.2 -0.2 0.3 -0.2 -0.3 0.8 -0.3 1.5 -0.7 0.2 -0.3 0.7 0.3 0.1 0.2 -0.1
Family relationship satisfaction 3.2 3.9 7.2 -2.0 2.6 0.9 -1.8 2.4 -1.3 2.2 -1.1 -2.0 -1.7 -2.2 -2.2 -1.7 -2.2 -0.6 -2.5 -2.0 -2.2 -1.5 -1.8 -2.7 -1.9 -2.2
Leg pain on walking 0.5 0.6 3.1 -0.8 1.1 -0.5 -0.5 0.4 -0.5 0.8 -1.8 -0.9 -0.7 -0.8 -0.7 -0.6 -0.7 -0.4 -0.8 -0.7 -0.8 -0.6 -0.7 -0.9 -0.7 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 1.3 0.3 0.3 -0.5 -0.2 0.4 0.2 0.1 -1.1 0.0 -0.2 -0.1 0.1 -0.2 -0.2 -0.0 0.0 -0.2 -0.1 -0.3 -0.2 0.1 -0.2 -0.2
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.2 0.2 0.3 0.3 -1.5 0.1 -0.7 0.6 0.2 -0.3 -1.1 -0.5 -0.6 -1.2 -0.5 -1.4 -0.1 -1.0 -0.6 -1.3 -1.0 -0.4 -0.9 -0.7
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.7 0.2 -0.2 -0.8 -0.2 -0.3 -0.4 -0.4 -0.4 0.3 0.3 0.2 0.2 0.1 0.4 0.5 0.3 0.2 0.4 0.0 0.3 -0.2 0.3 0.3
Medication: Aspirin 1.7 2.3 4.2 2.0 -1.8 1.0 1.3 -1.8 1.1 -1.6 1.4 1.7 1.4 1.7 1.7 1.3 1.7 0.6 1.6 1.5 1.6 1.2 1.5 1.4 1.5 1.6
Supplements: Vitamin C 3.6 4.3 9.4 -0.5 0.9 0.1 -2.4 1.7 -2.7 1.9 -1.0 -1.7 -2.6 -2.0 -1.9 -2.6 -1.9 -3.1 -1.2 -2.5 -1.8 -3.0 -2.4 -1.7 -2.4 -2.1
Knee pain experienced in last month 2.5 4.0 9.5 -3.1 1.8 0.5 -1.8 2.2 -1.2 2.3 -1.0 -2.4 -1.8 -2.1 -2.2 -1.6 -2.2 -1.3 -2.4 -1.9 -2.3 -1.3 -2.0 -2.3 -2.1 -2.1
Hypertension (Self-reported) 0.4 1.2 4.5 1.5 -2.1 0.7 0.0 -1.5 -0.1 -1.2 1.1 1.0 0.6 1.1 1.2 0.4 1.3 -0.8 1.6 0.8 1.2 0.3 0.7 1.0 0.8 1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.4 2.9 7.1 -0.9 0.5 0.3 -2.5 1.6 -2.7 1.4 -0.4 -1.5 -2.0 -1.5 -1.4 -2.2 -1.3 -2.5 -0.8 -1.9 -1.3 -2.3 -1.9 -1.5 -1.8 -1.6
Illnesses of father: Heart disease 0.1 0.2 1.1 0.8 -1.1 -0.6 0.4 -0.3 -0.3 -0.2 -0.1 0.4 -0.2 0.3 0.3 0.0 0.3 -0.7 0.5 -0.0 0.2 -0.3 -0.1 0.3 0.0 0.2
Illnesses of siblings: Diabetes 0.2 0.2 3.1 -0.0 -0.2 0.0 0.1 -0.6 -0.5 -0.4 1.8 0.2 0.4 0.3 0.3 0.1 0.4 0.2 0.4 0.4 0.4 0.3 0.3 0.2 0.3 0.4
Smoking status: Previous 0.3 0.5 2.4 0.5 -1.3 1.6 0.0 -0.7 -0.2 -0.6 1.0 0.8 -0.1 0.6 0.6 -0.2 0.6 -0.9 1.1 0.2 0.6 -0.4 0.1 0.7 0.2 0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.0 0.0 0.2 -0.2 -0.3 -0.2 -0.5 -0.2 -0.1 -0.0 0.2 -0.1 -0.1 0.1 0.0 -0.1 0.0 -0.2 0.2 -0.1 0.0 -0.2 -0.1 0.3 -0.1 -0.0
Whole body fat-free mass 2.6 14.8 18.5 -4.3 3.3 2.6 -4.2 3.5 -3.5 3.8 -4.2 -4.1 -4.0 -3.9 -4.0 -4.1 -3.8 -3.4 -3.4 -4.0 -3.8 -3.9 -4.1 -4.1 -4.1 -4.0
Leg fat-free mass (right) 1.5 8.2 12.8 -3.6 2.6 2.0 -3.0 2.6 -2.4 2.8 -3.4 -3.1 -3.0 -2.8 -3.0 -3.0 -2.8 -2.5 -2.5 -2.9 -2.8 -2.9 -3.0 -3.0 -3.1 -2.9
Arm fat percentage (left) 0.4 1.4 3.6 0.5 -0.5 -0.8 1.1 -1.2 1.9 -1.2 -0.7 1.0 1.2 1.2 1.3 1.4 1.2 1.4 1.2 1.3 1.2 1.2 1.3 1.4 1.2 1.2
Average weekly red wine intake 0.8 1.2 7.1 -1.1 1.5 0.6 -0.6 1.0 -0.8 0.9 -2.7 -0.6 -1.1 -0.8 -1.0 -1.2 -1.0 -0.8 -0.8 -1.1 -1.0 -1.2 -1.1 -1.0 -1.1 -1.1
Handedness (chirality/laterality): Left-handed 0.9 1.1 2.0 -1.4 0.1 1.2 -1.3 0.8 -1.3 0.9 -1.0 -0.9 -1.2 -0.9 -1.0 -1.2 -1.0 -1.4 -0.6 -1.1 -0.9 -1.2 -1.2 -0.8 -1.2 -1.0
Mood swings 0.9 1.6 2.5 -1.3 1.1 -1.5 -0.9 1.4 0.3 1.5 0.2 -1.4 -1.3 -1.5 -1.4 -0.9 -1.5 -0.6 -1.6 -1.4 -1.5 -1.1 -1.3 -1.3 -1.3 -1.5
Loneliness, isolation 0.6 0.9 1.9 -1.1 1.0 0.8 -0.8 1.0 -0.1 1.0 -1.4 -1.1 -0.7 -1.1 -1.1 -0.6 -1.0 -0.2 -1.2 -0.8 -1.0 -0.5 -0.8 -1.3 -0.9 -0.9
Long-standing illness, disability or infirmity 2.9 4.5 5.7 -1.6 2.1 1.6 -2.0 2.0 -1.9 2.3 0.1 -2.3 -2.3 -2.4 -2.3 -2.3 -2.2 -1.9 -2.1 -2.3 -2.3 -2.2 -2.3 -2.2 -2.4 -2.3
Ever had bowel cancer screening 3.0 3.6 11.4 -1.0 0.7 2.2 -1.8 1.4 -3.4 1.5 -0.6 -1.5 -2.2 -1.5 -1.6 -2.6 -1.6 -2.7 -1.0 -2.0 -1.5 -2.5 -2.1 -1.6 -2.0 -1.7
Diabetes diagnosed by doctor 0.9 1.5 3.9 0.0 -0.3 -0.1 1.7 -1.0 1.8 -1.0 0.8 0.7 1.6 1.0 1.1 1.6 1.0 2.0 0.6 1.5 1.0 1.8 1.4 0.9 1.3 1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.4 0.8 -1.2 1.1 0.2 -0.8 0.1 -0.9 -0.5 1.0 0.5 0.9 0.9 0.3 0.9 -0.2 1.2 0.6 0.9 0.2 0.6 0.9 0.6 0.8
Friendships satisfaction 0.2 0.2 0.5 -0.1 0.5 0.7 -0.3 0.6 -0.2 0.6 0.1 -0.4 -0.3 -0.5 -0.6 -0.2 -0.6 -0.0 -0.7 -0.4 -0.6 -0.1 -0.4 -0.7 -0.4 -0.5
Qualifications: nursing, teaching 0.9 1.4 2.2 -0.9 1.4 0.0 -0.6 1.1 -0.5 1.4 -0.7 -1.3 -1.2 -1.3 -1.5 -1.0 -1.4 -0.9 -1.5 -1.3 -1.4 -1.0 -1.3 -1.3 -1.3 -1.4
Commuting to job workplace: Walk 0.4 0.4 2.1 -0.9 0.5 -1.3 0.7 -0.1 0.7 -0.2 0.4 -0.1 0.7 -0.2 0.2 0.7 0.1 1.5 -0.3 0.5 0.2 0.9 0.6 0.0 0.6 0.3
Eye problems/disorders: Cataract 0.2 0.2 2.2 0.0 0.3 1.5 0.2 0.3 0.4 0.2 -1.2 -0.2 0.2 -0.3 -0.2 0.1 -0.1 0.4 -0.5 0.1 -0.2 0.3 0.1 -0.6 0.1 -0.0
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 2.8 -1.7 1.1 0.2 -1.5 1.6 -0.5 1.4 -1.0 -1.6 -1.5 -1.4 -1.4 -1.4 -1.4 -1.2 -1.2 -1.5 -1.5 -1.3 -1.5 -1.0 -1.5 -1.5
Medication for cholesterol 0.5 0.7 3.3 -1.5 1.8 -0.4 0.1 0.9 0.1 1.0 0.0 -1.0 -0.3 -0.9 -1.0 -0.3 -1.0 0.7 -1.4 -0.5 -1.0 0.0 -0.4 -0.8 -0.5 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 2.1 -1.0 1.3 1.4 -0.4 1.3 0.5 1.0 -1.2 -0.9 -0.5 -1.0 -0.9 -0.3 -1.0 0.3 -1.2 -0.6 -1.0 -0.2 -0.6 -1.3 -0.7 -0.9
Back pain experienced in last month 2.4 3.5 4.6 -2.1 1.5 2.1 -2.0 1.6 -1.8 1.8 -1.3 -1.9 -2.1 -1.8 -1.8 -2.1 -1.8 -1.9 -1.5 -2.1 -1.9 -2.1 -2.0 -1.7 -2.0 -2.0
Mineral and other dietary supplements 0.3 0.4 1.1 0.8 -1.1 -0.7 0.8 -0.6 0.4 -0.7 0.3 0.4 0.7 0.6 0.6 0.4 0.8 0.2 0.6 0.7 0.7 0.6 0.6 0.3 0.7 0.7
Breast cancer (self-reported) 0.2 0.3 0.7 0.6 -0.8 0.2 0.8 -0.2 0.8 -0.4 0.7 0.5 0.5 0.5 0.3 0.4 0.4 0.1 0.3 0.5 0.4 0.5 0.4 0.2 0.5 0.5
Asthma (self-reported) 0.2 0.4 1.8 0.8 -0.4 1.4 0.1 -0.6 -0.8 -0.7 -0.2 0.9 0.2 0.9 0.6 -0.0 0.7 0.1 1.0 0.2 0.7 -0.3 0.3 0.8 0.3 0.4
Osteoporosis (self-reported) 0.3 0.4 1.4 -1.2 0.7 1.2 -0.2 0.7 0.2 0.7 0.1 -0.7 -0.4 -0.7 -0.6 -0.1 -0.7 -0.0 -0.7 -0.4 -0.7 -0.1 -0.4 -0.3 -0.5 -0.6
Osteoarthritis (self-reported) 0.2 0.2 0.9 -0.3 0.5 -0.9 -0.3 -0.7 0.1 -0.4 -0.7 0.1 0.5 0.3 0.4 0.4 0.4 0.9 0.3 0.4 0.4 0.4 0.5 0.2 0.5 0.4
Medication: Aspirin 1.2 1.5 2.8 1.4 -1.7 0.8 1.2 -1.4 1.1 -1.3 1.2 1.3 1.1 1.4 1.4 1.1 1.4 0.4 1.4 1.2 1.4 1.0 1.2 1.1 1.2 1.4
Medication: Gliclazide 0.5 0.6 2.5 -1.6 1.2 -1.0 -0.5 0.6 0.1 0.8 0.5 -1.0 -0.4 -0.8 -0.6 -0.3 -0.8 0.4 -1.0 -0.5 -0.8 -0.1 -0.5 -0.8 -0.5 -0.7
Illnesses of father: None of the above (group 1) 0.7 0.9 1.9 0.8 -0.4 0.3 1.4 -0.8 1.2 -0.9 0.6 1.0 1.1 1.0 0.9 1.1 0.9 1.0 0.7 1.0 0.9 1.1 1.0 0.9 1.0 0.9
Smoking status: Current 0.6 1.0 4.9 0.9 -1.7 0.2 0.7 -1.4 0.2 -1.1 2.2 1.1 0.5 1.0 1.0 0.4 1.1 -0.4 1.4 0.6 1.1 0.1 0.6 0.8 0.7 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.1 0.4 -0.4 0.4 0.6 -0.4 0.8 -0.7 -0.0 0.7 0.8 0.6 0.7 1.0 0.6 0.9 0.6 0.8 0.7 0.9 0.8 0.9 0.8 0.7
Whole body water mass 2.8 15.9 19.6 -4.4 3.4 2.6 -4.3 3.7 -3.5 4.0 -4.4 -4.3 -4.1 -4.1 -4.1 -4.2 -4.0 -3.5 -3.6 -4.1 -4.0 -4.1 -4.2 -4.3 -4.3 -4.1
Leg predicted mass (right) 1.5 8.0 12.4 -3.5 2.5 2.1 -2.9 2.6 -2.4 2.7 -3.3 -3.0 -2.9 -2.8 -2.9 -2.9 -2.8 -2.4 -2.4 -2.9 -2.7 -2.9 -3.0 -3.0 -3.0 -2.9
Arm fat mass (left) 0.1 0.4 3.9 -1.1 0.9 0.0 -0.7 0.3 0.3 0.5 -2.0 -0.8 -0.5 -0.5 -0.5 -0.4 -0.5 -0.1 -0.4 -0.5 -0.5 -0.4 -0.5 -0.4 -0.5 -0.5
Number of self-reported non-cancer illnesses 1.4 2.4 3.3 -1.2 0.8 1.7 -1.8 1.3 -1.3 1.6 -1.6 -1.8 -1.6 -1.6 -1.5 -1.6 -1.5 -1.6 -1.4 -1.5 -1.6 -1.4 -1.6 -1.8 -1.6 -1.5
Average weekly champagne plus white wine intake 0.8 1.1 2.9 -1.2 1.4 -0.5 -1.7 0.9 -1.3 0.9 -1.0 -1.1 -0.8 -1.0 -0.9 -1.2 -0.9 -0.2 -1.0 -0.9 -1.0 -0.9 -0.9 -1.0 -0.9 -1.0
Miserableness 0.5 0.9 1.7 -0.6 0.8 -0.4 -0.9 0.9 -0.5 1.1 -0.4 -0.9 -1.3 -1.1 -1.0 -0.9 -1.0 -0.9 -0.8 -1.3 -1.1 -1.3 -1.1 -0.9 -1.1 -1.2
Guilty feelings 2.2 3.3 5.8 -1.4 1.2 1.1 -1.8 1.7 -2.4 1.7 -2.2 -1.8 -2.0 -1.8 -1.6 -2.1 -1.7 -2.2 -1.4 -1.9 -1.7 -2.1 -2.0 -1.7 -2.0 -1.8
Wears glasses or contact lenses 0.5 0.5 1.6 -0.8 1.2 1.3 -0.8 0.7 -0.8 0.7 -0.8 -0.7 -0.6 -0.7 -0.6 -0.5 -0.7 -0.1 -0.7 -0.6 -0.7 -0.5 -0.6 -0.4 -0.6 -0.7
Ever taken oral contraceptive pill 1.3 1.5 3.5 1.8 -1.9 1.0 1.1 -1.2 1.0 -1.2 1.2 1.5 1.0 1.3 1.3 1.0 1.2 0.5 1.3 1.0 1.2 0.8 1.1 1.3 1.1 1.2
Hearing aid user 0.7 0.8 4.0 -1.2 2.0 0.2 0.0 0.8 1.0 0.8 -1.0 -0.9 0.2 -0.7 -0.7 0.4 -0.8 1.6 -1.4 -0.0 -0.8 0.8 -0.0 -0.8 -0.2 -0.5
Mother’s age at death 0.5 0.6 2.8 0.0 0.7 -1.4 1.0 -0.1 1.7 -0.1 0.2 0.3 0.7 0.3 0.2 1.1 0.1 1.7 -0.2 0.5 0.1 1.0 0.7 0.6 0.6 0.3
Financial situation satisfaction 1.4 1.7 2.8 -1.2 1.2 0.3 -1.5 1.2 -1.5 1.3 -0.2 -1.2 -1.6 -1.2 -1.2 -1.6 -1.3 -1.4 -1.0 -1.5 -1.3 -1.7 -1.5 -1.1 -1.5 -1.4
Tinnitus: Yes, now most or all of the time 1.3 1.5 3.5 -1.4 0.6 1.9 -1.8 0.9 -1.8 1.0 -0.8 -1.0 -1.3 -1.1 -1.0 -1.5 -0.9 -1.4 -0.7 -1.2 -1.0 -1.4 -1.3 -1.0 -1.3 -1.1
Commuting to job workplace: Public transport 0.4 0.4 1.2 -0.5 -0.1 -1.1 0.6 -0.5 -0.2 -0.7 -0.4 0.4 0.5 0.7 0.8 0.5 0.7 0.6 0.9 0.6 0.8 0.3 0.6 1.1 0.6 0.6
Eye problems/disorders: Glaucoma 0.5 0.5 2.8 -0.1 0.2 -0.6 0.8 -0.3 1.4 -0.1 1.7 -0.0 0.8 0.1 0.1 1.0 0.1 1.4 -0.4 0.6 0.1 1.2 0.6 0.2 0.6 0.3
Medication: Blood pressure 3.1 5.9 13.3 3.2 -3.7 -0.5 1.6 -2.8 1.3 -2.7 1.6 2.7 2.1 2.7 2.8 2.0 2.8 0.4 3.0 2.4 2.7 1.8 2.2 2.6 2.4 2.7
Pain type(s) experienced in last month: Hip pain 1.5 1.9 4.5 -2.1 1.5 1.9 -1.0 1.4 -0.2 1.6 -1.4 -1.7 -1.1 -1.5 -1.4 -0.8 -1.6 -0.7 -1.7 -1.2 -1.6 -0.7 -1.3 -1.3 -1.3 -1.4
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.7 -0.2 -0.2 0.8 -0.7 -0.1 -0.3 -0.1 0.3 0.3 -0.0 0.1 0.1 -0.0 0.1 -0.0 0.3 -0.0 0.2 -0.3 0.0 0.2 0.0 0.1
High cholesterol (Self-reported) 0.2 0.3 3.3 0.6 -0.5 1.8 -0.6 0.0 -0.0 0.2 -0.7 -0.2 -0.4 -0.2 -0.1 -0.5 -0.1 -1.0 0.0 -0.3 -0.2 -0.5 -0.4 -0.4 -0.3 -0.2
Medication: Bendroflumethiazide 0.4 0.6 4.2 0.9 -1.1 0.4 -1.2 -0.5 -0.4 -0.1 -0.3 -0.1 -0.8 0.1 0.2 -0.8 0.1 -2.1 0.9 -0.5 0.2 -1.1 -0.6 0.6 -0.5 -0.1
Medication: Paracetamol 1.0 1.6 2.5 -1.0 1.6 0.7 -1.3 1.2 -0.6 1.2 -1.5 -1.2 -1.5 -1.3 -1.3 -1.4 -1.2 -1.0 -1.0 -1.5 -1.2 -1.6 -1.4 -1.1 -1.4 -1.4
Medication: Lisinopril 0.1 0.1 0.7 0.6 0.4 0.4 0.2 0.0 0.8 0.2 0.5 -0.2 0.2 -0.2 -0.1 0.3 -0.1 0.4 -0.4 0.1 -0.2 0.5 0.1 -0.2 0.1 -0.0
Medication: Atorvastatin 0.3 0.4 2.2 0.5 -0.0 1.5 -0.6 0.4 -0.7 0.6 -0.3 -0.7 -0.7 -0.7 -0.4 -0.6 -0.6 -1.0 -0.4 -0.6 -0.5 -0.6 -0.7 -0.6 -0.6 -0.6
Illnesses of father: High blood pressure 0.1 0.1 0.3 -0.2 -0.5 -0.5 0.4 -0.6 0.2 -0.5 0.3 0.3 0.3 0.5 0.4 0.2 0.4 -0.2 0.6 0.4 0.4 0.2 0.3 0.3 0.3 0.4
Alcohol drinker status: Never 0.2 0.2 1.0 -0.6 0.4 -0.9 0.7 0.1 1.0 0.1 -0.1 -0.4 0.4 -0.2 -0.3 0.5 -0.2 0.7 -0.5 0.3 -0.2 0.7 0.2 -0.1 0.2 0.0
Ever smoked 0.5 0.8 3.1 0.9 -1.5 1.6 0.3 -1.0 -0.7 -0.8 1.8 1.0 -0.2 0.7 0.7 -0.4 0.7 -1.4 1.3 0.0 0.7 -0.8 -0.0 0.5 0.1 0.5
Basal metabolic rate 2.1 11.5 16.0 -3.8 2.9 2.1 -3.7 3.1 -2.9 3.3 -4.0 -3.7 -3.5 -3.4 -3.5 -3.6 -3.4 -3.0 -3.0 -3.5 -3.3 -3.5 -3.6 -3.6 -3.6 -3.5
Leg fat percentage (left) 0.1 0.3 1.1 0.4 -0.2 -0.3 0.4 -0.7 1.0 -0.5 -0.8 0.4 0.5 0.7 0.6 0.6 0.5 0.5 0.6 0.6 0.5 0.6 0.5 0.7 0.6 0.5
Arm fat-free mass (left) 3.0 15.0 19.1 -4.1 3.4 2.5 -4.4 3.6 -3.5 3.8 -4.3 -4.2 -4.1 -4.0 -4.0 -4.1 -3.9 -3.5 -3.4 -4.0 -3.8 -4.0 -4.1 -4.1 -4.1 -4.0
Number of operations (self-reported) 0.6 0.8 4.8 -0.5 1.0 0.1 -1.2 0.8 -0.2 0.9 -2.2 -1.1 -0.8 -1.0 -0.9 -0.7 -0.9 -0.6 -0.9 -0.8 -0.9 -0.6 -0.8 -0.8 -0.8 -0.8
Average weekly beer plus cider intake 1.1 1.5 3.1 1.0 -1.3 -0.4 0.5 -1.4 0.4 -1.4 1.8 1.4 1.1 1.4 1.4 1.1 1.4 0.7 1.6 1.2 1.4 0.8 1.2 1.7 1.2 1.3
Irritability 0.6 1.0 5.5 1.5 -2.1 -1.0 0.1 -0.9 -0.1 -0.8 2.3 1.0 -0.0 0.9 0.7 0.2 0.8 -1.0 1.3 0.2 0.8 -0.4 0.2 0.9 0.3 0.6
Risk taking 0.9 1.2 5.0 -0.6 0.2 1.4 1.7 -0.4 1.7 -0.5 -0.3 0.6 1.5 0.6 0.4 1.4 0.5 2.2 -0.3 1.3 0.5 2.1 1.2 0.2 1.2 0.8
Ever had prostate specific antigen (PSA) test 2.5 2.9 7.1 -0.7 1.1 2.7 -1.8 1.4 -1.9 1.7 -0.4 -1.3 -2.0 -1.6 -1.7 -2.0 -1.6 -1.9 -1.4 -2.0 -1.7 -2.1 -1.9 -1.5 -1.9 -1.8
Fractured/broken bones in last 5 years 3.1 4.1 10.7 -0.9 1.0 1.1 -2.7 1.6 -3.3 1.7 -2.6 -1.5 -2.3 -1.6 -1.8 -2.5 -1.7 -2.6 -1.2 -2.2 -1.7 -2.6 -2.1 -1.6 -2.1 -1.9
Age started oral contraceptive pill 0.1 0.1 1.0 0.8 0.3 -0.4 -0.1 -0.0 0.2 0.0 0.3 0.1 0.4 -0.1 0.1 0.6 0.0 1.0 -0.3 0.3 0.0 0.6 0.4 0.1 0.3 0.1
Diastolic blood pressure, automated reading 0.3 1.0 2.2 -1.2 0.3 0.8 -0.8 1.1 -0.4 1.0 -1.2 -1.0 -1.1 -1.0 -1.0 -1.1 -1.1 -1.5 -0.8 -1.1 -1.0 -1.0 -1.2 -0.9 -1.1 -1.0
Ever depressed for a whole week 0.2 0.3 1.6 -1.3 0.4 0.3 0.0 0.6 0.3 0.6 1.3 -0.6 -0.4 -0.4 -0.5 -0.2 -0.5 -0.1 -0.5 -0.4 -0.5 -0.2 -0.4 -0.3 -0.4 -0.5
Unable to work because of sickness or disability 0.1 0.1 0.6 -0.2 0.8 0.1 0.5 0.1 0.4 -0.0 -0.2 -0.2 0.4 -0.0 0.1 0.4 -0.0 0.6 -0.3 0.3 -0.0 0.6 0.2 -0.1 0.2 0.1
Commuting to job workplace: Cycle 0.9 1.1 2.4 0.9 -0.3 1.0 1.4 -0.8 0.9 -1.0 0.1 1.2 1.3 1.0 0.9 1.2 1.0 1.5 0.6 1.2 1.0 1.3 1.2 0.6 1.2 1.1
Myopia 0.1 0.1 0.8 -0.2 0.8 -0.9 0.6 0.2 0.2 0.1 -0.3 0.1 0.1 -0.0 -0.1 0.2 -0.1 0.8 -0.3 -0.1 -0.2 0.1 0.1 -0.0 0.1 -0.1
Vascular/heart problems diagnosed by doctor 0.6 1.5 5.1 -1.9 2.2 -0.3 -0.4 1.6 -0.5 1.4 -1.2 -1.2 -0.9 -1.3 -1.4 -0.8 -1.5 0.4 -1.6 -1.1 -1.4 -0.7 -1.0 -1.1 -1.1 -1.4
Cholesterol lowering medication 0.2 0.2 0.8 0.9 -0.8 -0.4 -0.4 -0.4 -0.2 -0.4 -0.9 0.3 -0.1 0.3 0.4 -0.3 0.5 -0.8 0.7 -0.0 0.4 -0.5 -0.0 0.1 0.1 0.3
Medication: Omeprazole (e.g. Zanprol) 2.1 2.6 5.2 -1.1 1.2 2.3 -1.7 1.8 -1.9 1.7 -1.0 -1.5 -1.6 -1.6 -1.7 -1.7 -1.6 -1.6 -1.5 -1.6 -1.6 -1.4 -1.7 -1.8 -1.7 -1.6
Pain experienced in last month 4.7 7.8 10.8 3.1 -2.8 -1.6 2.9 -3.0 1.8 -3.1 2.8 3.3 2.8 3.0 3.0 2.5 3.1 1.8 3.0 2.8 3.1 2.3 2.8 3.1 2.9 3.0
Supplements: Calcium 0.6 0.6 2.8 -1.5 1.6 -0.1 0.4 0.5 1.7 0.7 0.1 -0.6 0.1 -0.5 -0.5 0.5 -0.7 1.1 -1.1 -0.1 -0.7 0.6 -0.1 -0.4 -0.2 -0.5
Basal cell carcinoma (self-reported) 3.1 3.6 5.5 -1.4 2.4 0.2 -1.7 2.1 -0.7 2.2 -1.8 -2.0 -1.9 -2.1 -2.1 -1.8 -2.2 -1.1 -2.3 -2.1 -2.2 -1.7 -1.9 -2.3 -2.0 -2.1
Heart attack/myocardial infarction (self-reported) 1.7 2.2 8.3 1.9 -0.8 -1.2 2.2 -0.9 2.9 -1.1 0.3 1.2 1.6 1.1 1.3 2.0 1.1 1.7 0.5 1.5 1.1 1.9 1.6 1.2 1.6 1.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.7 -0.3 0.1 -0.8 0.3 0.3 0.5 0.1 -0.9 -0.1 -0.1 -0.1 -0.2 0.2 -0.1 0.2 -0.1 -0.1 -0.1 0.1 -0.0 0.0 -0.0 -0.1
Heart disease (siblings) 0.1 0.2 0.8 0.3 -0.8 0.7 0.3 -0.5 -0.5 -0.3 0.9 0.4 -0.0 0.3 0.2 -0.2 0.3 -0.4 0.5 0.1 0.3 -0.2 0.1 0.1 0.1 0.2
Alcohol drinker status: Previous 0.1 0.2 1.6 0.2 -0.3 -1.3 0.4 -0.3 0.3 -0.3 -0.7 -0.0 0.3 0.1 0.4 0.2 0.3 0.1 0.3 0.3 0.3 0.3 0.3 0.1 0.3 0.3
Pack years of smoking 0.2 0.2 1.7 -1.3 0.3 -0.3 -0.4 0.1 0.7 0.4 0.2 -0.8 -0.1 -0.6 -0.4 -0.0 -0.4 0.0 -0.6 -0.1 -0.4 0.2 -0.2 -0.5 -0.2 -0.3
Impedance of whole body 6.5 32.8 39.4 5.5 -5.0 -3.1 5.8 -5.5 5.2 -5.7 5.7 5.9 6.2 5.8 5.9 6.3 5.8 5.7 5.0 6.2 5.7 6.3 6.3 6.1 6.3 6.0
Leg fat mass (left) 0.1 0.4 4.0 -0.8 0.7 0.5 -0.6 0.3 0.2 0.4 -2.0 -0.6 -0.5 -0.3 -0.4 -0.4 -0.4 -0.3 -0.3 -0.4 -0.4 -0.4 -0.5 -0.3 -0.5 -0.4
Arm predicted mass (left) 2.7 13.8 19.0 -3.8 3.0 2.3 -4.2 3.4 -3.5 3.6 -4.4 -4.0 -3.9 -3.8 -3.8 -4.0 -3.7 -3.6 -3.2 -3.8 -3.6 -3.9 -4.0 -3.9 -4.0 -3.8