Best TWAS P=4.35e-08 · Best GWAS P=5.33e-08 conditioned to 0.114
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | CYB5A | 0.31 | 0.27 | lasso | 2 | 0.21 | 4.2e-06 | 5.2 | 5.3 | 1.2e-07 | 0.87 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Spleen | CYB5A | 0.43 | 0.17 | lasso | 9 | 0.19 | 1.3e-05 | 5.3 | 5.2 | 1.8e-07 | 0.80 | 0.02 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CYB5A | 0.05 | 0.06 | lasso | 2 | 0.06 | 5.5e-07 | 5.3 | -5.3 | 8.9e-08 | -0.83 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CYB5A | 0.03 | 0.01 | blup | 85 | 0.01 | 7.2e-03 | 5.1 | -5.5 | 4.3e-08 | -0.83 | 0.02 | 0.90 | TRUE |