TWAS
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Models
Genes
Traits
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Traits
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Impedance of whole body
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chr18:71,224,566-72,650,685
Best TWAS P=4.35e-08 · Best GWAS P=5.33e-08 conditioned to 0.114
71.2M
71.4M
71.6M
71.8M
72M
72.2M
72.4M
72.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
CYB5A
0.03
0.01
blup
85
0.01
7.2e-03
5.1
-5.5
4.3e-08
-0.83
0.02
0.90
TRUE
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
CYB5A
0.05
0.06
lasso
2
0.06
5.5e-07
5.3
-5.3
8.9e-08
-0.83
0.01
0.99
FALSE
1
GTEx
Brain Cerebellar Hemisphere
CYB5A
0.31
0.27
lasso
2
0.21
4.2e-06
5.2
5.3
1.2e-07
0.87
0.02
0.98
FALSE
2
GTEx
Spleen
CYB5A
0.43
0.17
lasso
9
0.19
1.3e-05
5.3
5.2
1.8e-07
0.80
0.02
0.96
FALSE