Best TWAS P=1.58e-08 · Best GWAS P=3.26e-08 conditioned to 2.52e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | LBR | 0.12 | 0.04 | lasso | 3 | 0.02 | 1.8e-02 | 5.5 | 5.3 | 1.2e-07 | 0.28 | 0 | 0.98 | FALSE |
| 2 | GTEx | Artery Tibial | LBR | 0.49 | 0.40 | lasso | 6 | 0.40 | 3.4e-33 | 5.5 | 5.6 | 2.7e-08 | 0.32 | 0 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | AC092811.1 | 0.13 | 0.13 | lasso | 2 | 0.12 | 1.9e-09 | 5.5 | 5.4 | 6.2e-08 | 0.31 | 0 | 1.00 | FALSE |
| 4 | GTEx | Esophagus Muscularis | LBR | 0.52 | 0.29 | enet | 44 | 0.30 | 2.0e-18 | 5.5 | 5.7 | 1.6e-08 | 0.26 | 0 | 1.00 | TRUE |
| 5 | GTEx | Nerve Tibial | LBR | 0.13 | 0.16 | lasso | 1 | 0.15 | 9.6e-11 | 5.5 | 5.5 | 3.9e-08 | 0.31 | 0 | 1.00 | FALSE |