[Hub]/) : Traits : Impedance of whole body :

chr2:205,851,076-207,874,372

Best TWAS P=1.59e-12 · Best GWAS P=7.13e-12 conditioned to 0.441

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NDUFS1 0.10 0.09 lasso 9 0.09 1.2e-10 5.8 -6.5 7.3e-11 -0.62 0.12 0.88 FALSE
2 GTEx Adipose Subcutaneous NDUFS1 0.08 0.05 lasso 5 0.01 2.0e-02 5.2 -5.7 1.4e-08 -0.55 0.46 0.45 FALSE
3 GTEx Artery Aorta NDUFS1 0.11 0.07 enet 29 0.01 6.7e-02 6.1 -5.4 6.8e-08 -0.47 0.23 0.60 FALSE
4 GTEx Artery Tibial NDUFS1 0.16 0.15 enet 14 0.15 3.9e-12 5.6 -5.7 1.2e-08 -0.53 0.72 0.28 FALSE
5 GTEx Artery Tibial ZDBF2 0.07 0.02 lasso 5 0.02 2.1e-02 5.8 5.9 3.9e-09 0.82 0.22 0.67 FALSE
6 GTEx Brain Cerebellum AC007383.4 0.23 0.05 lasso 3 0.18 3.9e-06 6.7 -5.8 8.6e-09 -0.48 0.05 0.79 FALSE
7 GTEx Brain Putamen basal ganglia NDUFS1 0.16 0.06 enet 6 0.05 2.9e-02 4.9 -6.5 1.1e-10 -0.74 0.09 0.39 FALSE
8 GTEx Breast Mammary Tissue (Female) NRP2 0.29 0.03 lasso 6 0.06 5.7e-03 5.7 5.2 2.1e-07 0.39 0.08 0.30 FALSE
9 GTEx Breast Mammary Tissue (Female) AC007362.1 0.46 -0.01 lasso 14 0.00 4.6e-01 5.4 5.5 4.4e-08 0.48 0.06 0.36 FALSE
10 GTEx Cells Transformed fibroblasts NDUFS1 0.33 0.42 enet 28 0.40 3.2e-32 5.5 -6.0 2.6e-09 -0.60 0.64 0.36 FALSE
11 GTEx Cells Transformed fibroblasts AC007383.4 0.18 0.15 enet 28 0.17 4.5e-13 5.5 -6.2 5.7e-10 -0.60 0.66 0.34 FALSE
12 GTEx Colon Sigmoid AC007383.4 0.15 0.14 enet 13 0.09 3.8e-04 5.7 -6.8 1.3e-11 -0.61 0.30 0.58 FALSE
13 GTEx Colon Transverse AC007383.4 0.14 0.09 lasso 2 0.06 8.8e-04 5.2 -5.7 1.1e-08 -0.50 0.22 0.29 FALSE
14 GTEx Esophagus Gastroesophageal Junction NDUFS1 0.16 0.09 enet 22 0.03 2.4e-02 5.7 -7.0 3.7e-12 -0.68 0.10 0.82 FALSE
15 GTEx Esophagus Gastroesophageal Junction AC007383.4 0.21 0.17 enet 11 0.14 8.5e-06 5.7 -5.8 7.5e-09 -0.56 0.40 0.50 FALSE
16 GTEx Esophagus Mucosa NDUFS1 0.09 0.05 lasso 2 0.02 8.6e-03 5.9 -6.5 9.5e-11 -0.67 0.13 0.79 FALSE
17 GTEx Esophagus Mucosa AC007383.4 0.16 0.08 enet 26 0.10 5.8e-07 5.7 -5.7 1.2e-08 -0.71 0.10 0.89 FALSE
18 GTEx Esophagus Muscularis NDUFS1 0.17 0.19 enet 21 0.18 5.1e-11 5.7 -5.9 3.9e-09 -0.47 0.61 0.39 FALSE
19 GTEx Esophagus Muscularis AC007383.4 0.10 0.13 enet 4 0.10 1.3e-06 5.7 -5.8 8.9e-09 -0.53 0.57 0.43 FALSE
20 GTEx Heart Atrial Appendage AC007383.4 0.12 0.10 enet 21 0.09 9.8e-05 6.1 -5.8 5.9e-09 -0.47 0.58 0.41 FALSE
21 GTEx Heart Left Ventricle AC007383.4 0.17 0.13 enet 19 0.16 9.7e-09 5.7 -6.3 3.5e-10 -0.58 0.63 0.37 FALSE
22 GTEx Liver AC007383.4 0.27 0.10 lasso 4 0.03 4.4e-02 4.9 -5.2 2.6e-07 -0.49 0.08 0.30 FALSE
23 GTEx Muscle Skeletal NDUFS1 0.20 0.14 enet 20 0.12 4.0e-12 5.8 -5.6 2.0e-08 -0.52 0.73 0.27 FALSE
24 GTEx Muscle Skeletal AC007383.4 0.23 0.18 enet 38 0.20 2.1e-19 5.8 -5.3 1.0e-07 -0.49 0.80 0.20 FALSE
25 GTEx Nerve Tibial NDUFS1 0.13 0.08 enet 14 0.05 3.1e-04 4.7 -5.7 1.2e-08 -0.48 0.72 0.25 FALSE
26 GTEx Nerve Tibial AC007383.4 0.14 0.06 lasso 6 0.05 3.0e-04 6.0 -6.6 4.0e-11 -0.56 0.36 0.60 FALSE
27 GTEx Testis NDUFS1 0.15 0.08 lasso 6 0.08 2.1e-04 6.8 -7.1 1.6e-12 -0.93 0.01 0.98 TRUE
28 METSIM Adipose NDUFS1 0.12 0.18 lasso 4 0.17 5.2e-25 5.6 -5.4 7.9e-08 -0.53 0.68 0.32 FALSE
29 METSIM Adipose ZDBF2 0.03 0.00 bslmm 436 0.00 1.1e-01 -5.7 6.8 1.1e-11 0.78 0.21 0.64 FALSE
30 ROSMAP Brain Pre-frontal Cortex INO80D 0.22 0.34 lasso 2 0.35 2.0e-47 5.4 5.8 4.8e-09 0.64 0.59 0.41 FALSE
31 ROSMAP Brain Pre-frontal Cortex ZDBF2 0.12 0.11 lasso 2 0.11 8.0e-14 5.6 5.7 1.1e-08 0.80 0.79 0.21 FALSE
32 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFS1 0.05 0.03 blup 51 0.04 6.2e-05 6.1 -5.5 4.7e-08 -0.50 0.31 0.67 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma GPR1 0.05 0.04 lasso 3 0.04 1.7e-04 6.9 -6.7 3.0e-11 -0.98 0.00 0.98 FALSE