Best TWAS P=1.07e-08 · Best GWAS P=1.18e-09 conditioned to 0.00298
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TEKT2 | 0.01 | 0.02 | lasso | 1 | 0.02 | 0.00024 | 5.1 | 5.2 | 2.7e-07 | 0.33 | 0.01 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | MAP7D1 | 0.06 | 0.01 | blup | 33 | 0.04 | 0.00131 | 5.0 | 5.2 | 2.5e-07 | 0.75 | 0.02 | 0.44 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | TRAPPC3 | 0.07 | 0.02 | blup | 38 | 0.03 | 0.00567 | 5.0 | 5.7 | 1.1e-08 | 0.69 | 0.05 | 0.38 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | COL8A2 | 0.04 | 0.03 | blup | 30 | 0.03 | 0.00026 | 5.2 | -5.4 | 5.8e-08 | -0.54 | 0.02 | 0.92 | FALSE |