TWAS
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Models
Genes
Traits
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Traits
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Impedance of whole body
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chr3:156,165,788-157,574,195
Best TWAS P=1.38e-07 · Best GWAS P=1.15e-08 conditioned to 0.0167
156.2M
156.4M
156.6M
156.8M
157M
157.2M
157.4M
157.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
METSIM
Adipose
CCNL1
0.03
0.01
blup
432
0.02
9.6e-04
-4.7
-5.3
1.4e-07
0.83
0.05
0.95
TRUE
2
YFS
Blood
CCNL1
0.09
0.16
bslmm
434
0.17
3.0e-52
-5.4
-5.2
2.3e-07
0.79
0.08
0.92
FALSE
3
The Cancer Genome Atlas
Thyroid Carcinoma
CCNL1
0.06
0.02
lasso
3
0.04
6.9e-05
-5.6
5.2
2.6e-07
-0.85
0.01
0.97
FALSE