Best TWAS P=1.96e-11 · Best GWAS P=5.54e-09 conditioned to 0.0183
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PTPN13 | 0.13 | 0.18 | bslmm | 418 | 0.18 | 6.8e-22 | -5.3 | 5.9 | 4.1e-09 | -0.53 | 0.13 | 0.87 | FALSE |
| 2 | GTEx | Adrenal Gland | PTPN13 | 0.15 | 0.05 | lasso | 3 | 0.06 | 2.8e-03 | -5.8 | 5.2 | 2.5e-07 | -0.84 | 0.03 | 0.80 | FALSE |
| 3 | GTEx | Artery Aorta | MAPK10 | 0.15 | 0.17 | enet | 16 | 0.17 | 1.4e-09 | -5.6 | 5.9 | 4.3e-09 | -0.96 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Colon Sigmoid | MAPK10 | 0.25 | 0.11 | lasso | 8 | 0.07 | 1.6e-03 | -5.6 | 5.7 | 1.1e-08 | -0.89 | 0.02 | 0.95 | FALSE |
| 5 | GTEx | Nerve Tibial | MAPK10 | 0.08 | 0.01 | enet | 17 | 0.03 | 1.7e-03 | -5.7 | 5.2 | 2.4e-07 | -0.74 | 0.01 | 0.96 | FALSE |
| 6 | GTEx | Ovary | PTPN13 | 0.18 | -0.01 | enet | 29 | 0.07 | 8.4e-03 | -5.8 | 6.7 | 2.0e-11 | -0.58 | 0.04 | 0.70 | TRUE |
| 7 | GTEx | Thyroid | PTPN13 | 0.41 | 0.31 | lasso | 6 | 0.30 | 3.2e-23 | -5.8 | -5.6 | 1.6e-08 | 0.99 | 0.01 | 0.99 | FALSE |