Hub : Genes

PTPN13

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1290	0.0280	5.6e-17	0.180	0.168	0.179	0.184	0.184	2.2e-21	5.6e-20	2.8e-21	6.8e-22	7.5e-22
2	GTEx	Adrenal Gland	0.1469	0.0677	3.0e-03	0.054	NA	0.039	NA	0.063	5.3e-03	NA	1.6e-02	NA	2.8e-03
3	GTEx	Brain Caudate basal ganglia	0.2630	0.0910	1.0e-03	0.155	NA	0.110	NA	0.058	3.3e-05	NA	4.6e-04	NA	9.5e-03
4	GTEx	Colon Sigmoid	0.2050	0.0820	3.9e-03	0.032	NA	0.020	NA	0.057	2.7e-02	NA	6.6e-02	NA	4.6e-03
5	GTEx	Esophagus Muscularis	0.1190	0.0430	3.6e-04	-0.003	NA	0.007	NA	0.004	5.8e-01	NA	1.2e-01	NA	1.9e-01
6	GTEx	Ovary	0.1790	0.0720	2.3e-03	-0.012	NA	0.071	NA	0.025	9.9e-01	NA	8.4e-03	NA	8.2e-02
7	GTEx	Thyroid	0.4080	0.0610	8.3e-16	0.310	NA	0.251	NA	0.299	3.8e-24	NA	3.2e-19	NA	3.2e-23
8	ROSMAP	Brain Pre-frontal Cortex	0.0918	0.0292	2.3e-08	0.032	0.068	0.049	0.066	0.058	5.1e-05	4.7e-09	5.9e-07	7.5e-09	5.4e-08
9	TCGA	Brain Lower Grade Glioma	0.0631	0.0314	1.2e-04	0.046	0.029	0.038	NA	0.038	5.3e-06	2.8e-04	3.7e-05	NA	3.3e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.8	3.4	0.6	-0.1	0.5	1.0	0.3	0.1	-0.6	1.2	1.8
Bipolar Disorder or Schizophrenia	0.3	0.6	2.0	-0.0	-1.0	0.5	-0.9	-0.8	0.9	0.4	0.3	1.4
Depressed Affect (Nagel 2018)	0.9	1.9	8.4	-1.2	-1.3	-1.0	1.0	-0.5	-2.9	1.0	-1.2	0.4
Depression (Nagel 2018)	0.4	0.6	1.8	-0.6	-1.3	-0.5	0.5	0.1	-0.8	0.8	-1.0	0.2
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.2	1.1	0.5	0.7	1.0	1.8	0.7	-0.3	-0.5	-1.2
Neuroticism (Nagel 2018)	0.9	2.1	9.1	-0.9	-1.6	-0.3	0.2	-2.0	-3.0	1.0	-0.8	0.6
Schizophrenia (2018)	0.5	1.0	4.1	-0.5	-1.1	0.2	-2.0	-0.9	1.1	1.0	-0.6	0.3
Schizophrenia vs Biploar Disorder	0.6	0.7	3.9	-0.5	-0.3	0.5	-2.0	0.3	0.8	0.7	-0.4	-0.9
Worry (Nagel 2018)	0.5	1.0	3.6	0.6	-0.2	1.0	-0.3	-1.9	-1.4	-0.3	0.6	1.3
Alzheimer’s Disease (in mother)	1.1	1.3	3.0	-1.5	-0.8	-1.7	-0.2	-0.4	-1.1	1.3	-1.2	-1.1
Alzheimer’s Disease (in father)	2.0	2.1	4.2	2.0	-0.9	1.9	1.3	0.1	1.3	0.1	1.8	2.0
Alzheimer’s Disease (including proxy)	0.3	0.5	1.5	0.0	-0.7	-0.1	-0.8	-0.8	-0.3	1.2	0.4	-1.0
Crohns Disease (2017)	0.7	1.5	4.3	-0.9	-2.0	-0.6	0.6	-0.1	-1.0	0.8	-1.3	2.1
Irritable Bowel Disease (IBD)	0.3	0.8	3.0	0.9	-0.1	0.7	1.0	1.1	0.5	-0.3	0.5	1.7
Ulcerative Colitis (UC)	1.2	2.3	5.1	2.3	1.4	1.7	1.0	1.3	1.7	-1.2	2.0	0.8
Major Depression (MDD)	0.4	0.5	1.4	-0.8	-0.1	-0.8	-0.9	-0.2	1.2	0.6	-0.8	-0.2
Reaction Time	2.1	4.1	7.0	2.0	1.7	1.7	2.0	-1.1	1.8	-2.2	2.5	2.7
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.8	-0.9	-0.5	-1.2	-0.5	0.6	-0.8	1.1	-2.2	-2.2
Breast Cancer	1.1	2.6	6.8	-0.4	2.5	-1.5	0.4	2.3	1.3	-0.7	-0.5	-2.6
Ovarian Cancer	3.0	3.9	8.3	2.9	1.1	2.6	2.3	0.9	1.2	-1.9	1.6	2.4
Prostate Cancer	1.0	1.4	6.2	0.7	-0.6	1.3	-0.3	-2.5	-0.7	-0.5	1.2	1.3
Age at First Birth	0.1	0.2	0.5	0.6	0.5	0.4	0.1	-0.1	0.7	-0.4	0.2	-0.1
Bipolar Disorder (2011)	0.7	0.7	3.0	-0.4	-0.7	0.2	0.7	0.2	-1.1	0.3	-0.7	1.7
Body Mass Index (BMI) (2010)	1.2	1.7	4.1	-1.2	-1.8	-0.8	-1.1	-1.3	-1.4	2.0	-1.0	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	2.5	-0.4	-1.3	0.0	0.4	-0.3	-0.5	0.6	0.1	1.6
Crohns Disease (2012)	0.5	0.8	4.5	0.4	-0.9	0.3	1.1	0.3	-0.0	-0.0	-0.2	2.1
Mean Putamen Volume	3.0	3.5	7.0	-2.3	-1.8	-2.7	-2.2	-1.0	-1.3	1.9	-1.1	-1.7
Fasting Glucose	1.2	1.5	7.2	0.2	-0.9	0.4	2.7	1.3	-0.1	0.0	-0.8	1.7
HbA1C	0.3	0.3	1.4	0.1	-0.2	0.4	-0.9	-1.2	-0.5	-0.1	-0.1	-0.7
HDL Cholesterol	2.9	4.8	13.5	1.5	3.7	1.1	0.9	2.3	3.6	-2.1	1.6	-0.7
LDL Cholesterol	1.1	1.8	4.6	1.4	-1.2	1.4	-1.7	-1.5	-0.5	0.8	2.1	0.3
Lupus	1.4	2.1	5.6	2.3	-0.4	2.4	0.7	-1.1	0.7	-0.6	1.6	1.7
Neuroticism (2016)	3.0	4.3	9.0	-2.7	-1.5	-2.3	-1.1	-2.1	-3.0	0.5	-2.9	-0.9
Primary Biliary Cirrhosis	0.8	1.2	7.6	0.5	-0.1	0.6	-2.8	0.3	0.5	0.9	0.7	-0.7
Rheumatoid Arthritis	0.6	0.8	2.5	-0.6	-1.4	-0.6	0.7	-0.1	-1.1	0.9	-1.6	0.3
Schizophrenia (2014)	0.4	0.8	2.7	0.4	-0.6	0.9	-1.4	-0.4	1.6	0.1	0.3	1.0
Triglycerides	6.1	10.1	26.2	-1.1	-5.1	-0.1	-2.9	-4.5	-4.9	2.9	-0.9	1.2
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.4	1.1	0.9	0.8	0.8	1.8	-0.3	-0.3	1.1	0.2
Ulcerative Colitis	3.4	4.9	8.2	2.9	1.9	2.3	1.8	2.5	2.5	-1.2	2.9	1.1
Blood Eosinophil Count	0.3	2.1	6.6	-0.3	1.8	-0.3	2.6	0.1	0.4	-2.2	-1.4	1.3
Blood Platelet Count	1.2	14.4	49.8	2.5	4.3	3.3	3.8	-0.7	0.8	-7.1	2.6	4.6
Blood Red Count	1.4	13.5	49.6	-1.4	3.9	-2.1	7.0	5.8	2.6	-2.2	-2.1	0.2
Blood White Count	0.2	1.4	4.5	-0.6	0.4	-0.1	-1.4	-1.7	-1.7	-2.1	0.1	-0.2
Heel T-Score	1.2	9.6	32.6	0.5	-4.4	2.4	0.7	-3.4	-5.7	-0.1	1.4	3.8
BMI	0.5	3.1	10.0	-2.3	-2.0	-1.5	0.4	-0.3	-3.2	1.3	-2.0	0.7
Height	1.0	19.0	60.2	-3.9	-3.6	-4.4	-2.5	1.4	-0.9	7.8	-5.1	-5.3
Waist Hip Ratio (WHR)	0.3	1.5	3.9	1.8	-0.5	2.0	1.3	-0.2	-0.4	-0.6	1.7	1.1
Systolic Blood Pressure	2.3	11.3	22.1	3.5	2.4	4.5	3.3	0.6	1.5	-4.3	3.2	4.7
Smoking Status	0.3	0.8	2.5	0.9	0.5	-0.1	-0.1	-0.0	1.2	-0.4	1.3	-1.6
Allergy or Eczema	0.6	1.6	5.4	-1.2	-2.3	-0.7	-0.7	-0.6	-1.1	1.2	-1.6	1.1
Cardiovascular Disease	1.7	5.7	17.9	2.5	0.7	3.2	1.2	0.9	1.1	-2.5	2.6	4.2
Hypothyroidism (self reported)	8.0	18.3	39.1	-3.6	-5.9	-2.1	-4.8	-3.3	-4.8	6.2	-3.6	-1.8
Respiratory disease	0.5	1.2	3.9	-0.9	-2.0	-0.5	0.3	-0.5	-0.3	0.8	-1.7	1.4
Type 2 Diabetes (T2D) (2018)	0.5	1.0	2.5	-1.6	0.4	-1.6	0.3	-0.2	-0.8	-0.1	-1.3	-1.2
Lung FEV1/FVC ratio	0.2	1.2	4.1	0.2	1.2	-0.5	2.0	1.1	-0.2	-1.9	0.5	-0.4
Lung FVC	1.2	6.3	14.7	1.5	-1.4	1.4	-3.3	-3.8	-3.5	0.7	2.9	-1.9
Neuroticism	1.0	2.5	10.3	-0.3	-1.9	0.4	-0.7	-3.2	-2.5	0.6	-0.2	0.7
Chronotype (morning person)	0.1	0.1	0.3	0.3	-0.5	0.4	-0.5	-0.5	-0.1	-0.0	-0.0	0.4
Hair Pigment	0.0	0.8	1.8	-1.3	-0.3	-1.2	0.3	-0.9	-1.2	0.3	-1.2	0.1
Tanning	0.3	3.3	8.8	-0.3	-2.2	-0.6	-2.3	-1.5	-0.8	2.7	-0.5	-3.0
Hand grip strength (left)	1.2	3.3	10.8	-1.9	-2.2	-1.1	-1.5	0.7	-1.4	3.3	-1.9	-0.9
Number of treatments/medications taken	0.5	1.0	3.5	-0.7	-0.7	-0.5	-1.4	-1.9	-1.2	-0.5	-0.7	0.1
Average weekly spirits intake	2.9	3.6	6.7	-2.6	-2.0	-2.4	-0.6	-0.4	-1.8	2.5	-2.5	-0.8
Sensitivity / hurt feelings	1.9	3.2	6.2	-1.9	-2.5	-1.2	-0.6	-2.4	-1.9	1.2	-2.3	1.0
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.6	-1.6	-0.7	-1.3	0.4	-0.5	-1.0	0.9	-1.6	-0.3
Hearing difficulty/problems: Yes	3.4	5.2	8.5	-2.8	-1.0	-2.8	-1.8	-0.7	-2.9	2.0	-2.5	-2.8
Relative age of first facial hair	0.2	0.4	1.6	0.5	-0.3	0.4	-0.3	-0.6	0.1	-1.3	0.9	0.6
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	3.2	-1.4	-1.2	-1.2	-0.7	-0.9	-1.8	1.5	-1.2	-0.9
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.3	-2.1	-0.9	-2.0	-1.1	-0.4	-0.1	0.8	-1.9	-0.4
Ever had hysterectomy (womb removed)	1.0	1.2	3.2	-1.8	-0.2	-1.2	-0.6	-0.6	-1.1	-0.0	-1.7	0.9
Systolic blood pressure, automated reading	2.2	6.3	18.0	2.1	1.5	2.5	3.1	0.3	0.9	-3.4	2.0	4.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	-0.4	-0.4	-1.0	0.4	-0.8	-0.3	0.1	-0.0	-0.0
Angina	1.0	1.3	5.4	-0.3	1.9	-0.6	0.2	-0.9	1.0	-2.3	0.8	-0.2
Medication for hormone replacement therapy	0.7	0.8	2.8	0.3	1.3	0.3	-0.9	0.4	1.7	-0.7	-0.2	-1.0
Vitamin and mineral supplements	0.5	0.7	1.8	0.8	-0.1	0.9	-1.4	-1.1	-0.6	0.7	0.9	0.0
Supplements: Zinc	0.6	0.7	2.4	-0.8	0.5	-1.0	-0.7	-0.7	0.9	-0.4	-0.4	-1.6
Medication: Co-codamol	2.7	3.1	6.7	-2.6	-1.6	-2.2	0.0	0.6	-2.1	1.4	-2.5	-0.7
Medication: Metformin	1.1	1.5	3.9	-2.0	-0.4	-1.7	0.4	0.2	-1.0	1.0	-1.8	-1.1
Diabetes (father)	1.1	1.3	4.8	-0.6	1.0	-1.7	-0.1	0.1	1.4	0.0	-0.9	-2.2
Diabetes (mother)	1.0	1.3	2.8	-1.7	-0.2	-1.4	-1.3	-0.4	-0.2	1.3	-1.4	-1.3
Severe depression (siblings)	1.7	1.9	4.5	-2.1	-1.2	-1.3	-0.8	-0.6	-1.4	1.8	-1.6	-1.1
Pack years adult smoking proportion	0.2	0.4	1.9	0.1	0.9	-0.2	0.4	-0.4	-0.2	-1.4	-0.3	-0.4
Impedance of leg (right)	4.8	23.0	38.1	6.0	5.1	5.1	3.0	2.0	6.2	-5.8	5.2	2.4
Leg fat-free mass (left)	3.5	18.6	33.5	-5.6	-4.1	-5.0	-2.1	-0.0	-3.9	5.7	-5.8	-2.9
Trunk fat percentage	0.1	0.4	1.1	-0.1	0.5	-0.4	0.4	0.3	0.9	-1.1	-0.3	1.0
Hand grip strength (right)	0.8	2.3	8.5	-1.3	-2.3	-0.6	-0.7	0.6	-1.4	2.9	-1.3	-0.6
Townsend deprivation index at recruitment	2.9	4.1	7.7	-2.8	-2.6	-2.4	-1.3	-1.1	-1.2	2.3	-2.6	-0.3
Current tobacco smoking	0.2	0.3	0.9	0.4	0.3	-0.1	0.1	-0.9	0.7	-0.8	0.3	-0.2
Average weekly fortified wine intake	0.2	0.2	0.7	-0.3	-0.1	-0.5	-0.0	0.6	-0.5	0.2	-0.4	-0.8
Maternal smoking around birth	0.3	0.4	1.0	-0.5	0.3	-0.5	-0.6	-1.0	-0.0	-0.5	-0.7	-1.0
Fed-up feelings	1.7	3.1	9.3	-2.1	-1.6	-1.8	0.7	-0.9	-3.0	1.4	-2.1	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.6	-0.0	-0.3	0.0	0.7	-0.7	0.1	-0.6	-0.1	0.8
Relative age voice broke	0.1	0.2	0.4	0.6	0.1	0.6	0.2	-0.3	0.3	-0.6	0.4	0.5
Taking other prescription medications	2.9	4.4	9.2	-2.0	-2.2	-1.0	-2.1	-3.0	-2.8	1.3	-2.6	-0.0
Age when periods started (menarche)	0.3	0.7	2.3	0.7	-0.1	0.7	-1.1	-1.5	0.0	-0.4	1.3	0.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	3.3	-1.5	-0.8	-1.2	-0.5	0.5	-1.1	0.6	-1.8	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.8	18.0	-1.4	-2.9	-0.4	-0.6	-3.1	-4.2	0.9	-1.6	1.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.7	-0.8	-0.3	-0.2	-0.3	-0.8	0.2	0.8	-0.0	0.4
Qualifications: CSEs or equivalent	0.4	0.6	1.1	0.7	0.2	1.0	0.3	-1.1	-0.6	-1.0	0.7	0.7
Serious illness, injury or assault to yourself	0.3	0.4	1.1	0.3	0.1	0.4	0.6	1.0	-0.3	-0.7	1.0	0.5
High blood pressure	1.1	3.1	6.7	1.8	1.8	2.1	0.6	0.6	1.3	-2.2	1.7	2.6
Hayfever, allergic rhinitis or eczema	1.4	3.1	9.1	-1.6	-3.0	-1.1	-1.0	-1.0	-1.5	2.0	-2.4	1.0
Multivitamins +/- minerals	0.6	0.7	2.1	-0.9	-0.9	-0.5	1.3	0.6	0.0	-0.1	-1.4	0.8
Stomach or abdominal pain in last month	0.3	0.4	1.7	-0.4	-0.0	-0.3	-0.7	-1.3	0.7	0.8	-0.5	-0.3
Supplements: Glucosamine	0.9	1.2	4.2	-1.4	-0.6	-1.4	0.3	1.2	-0.0	1.0	-2.0	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	-0.7	-0.8	0.1	-0.4	-0.8	-0.5	1.1	-0.4	0.2
Medication: Atenolol	1.3	1.6	3.7	0.4	1.3	0.2	1.9	1.4	1.4	-1.8	1.0	0.3
Medication: Levothyroxine sodium	1.6	2.8	5.2	-1.5	-2.3	-0.4	-1.9	-1.5	-2.3	2.1	-1.2	-0.1
Sitting height	1.3	8.9	20.3	-3.2	-3.8	-2.7	-1.1	-0.9	-2.4	4.5	-4.2	-1.5
Chronic bronchitis/emphysema (father)	1.2	1.5	4.4	0.6	2.1	-0.4	0.9	1.1	1.1	-2.1	0.7	-0.6
High blood pressure (mother)	0.7	0.9	3.7	0.8	0.7	1.0	-0.2	-0.1	0.5	-1.2	1.0	1.9
Body mass index (BMI)	0.8	3.6	8.4	-2.7	-2.1	-2.3	-0.3	-0.6	-2.9	1.5	-2.1	0.5
Impedance of leg (left)	4.4	21.3	36.0	6.0	4.3	5.3	2.9	1.3	5.8	-5.5	5.3	2.9
Leg predicted mass (left)	3.5	18.5	33.5	-5.6	-4.1	-5.1	-2.0	0.0	-3.9	5.6	-5.8	-2.9
Trunk fat mass	0.3	1.3	3.4	-1.7	-1.0	-1.7	-0.1	0.3	-0.4	0.9	-1.8	0.1
Waist circumference	0.8	2.8	5.4	-2.2	-2.0	-2.0	-0.4	-0.2	-2.3	1.7	-1.9	-0.0
Number of incorrect matches in round	0.6	1.1	5.0	-1.1	2.2	-0.9	0.4	0.7	0.9	-0.9	-0.3	-0.6
Past tobacco smoking	0.3	0.5	1.6	-0.7	-0.1	-0.3	0.6	-0.8	-0.7	0.0	-1.3	0.8
Alcohol usually taken with meals	0.3	0.5	1.9	-0.2	0.8	-0.5	-0.2	0.4	1.3	0.1	-0.4	-1.4
Nervous feelings	0.5	1.0	4.8	-0.1	-0.9	0.2	-1.1	-2.2	-1.2	0.7	-0.5	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	1.5	0.8	0.7	1.0	1.2	-0.5	-0.4	-1.1	0.8	0.8
Hearing difficulty/problems with background noise	1.9	3.0	14.8	-1.5	0.5	-2.0	-1.2	-0.3	-0.2	1.2	-1.5	-3.8
Hair/balding pattern: Pattern 2	0.4	0.5	2.5	-0.4	-0.1	-0.7	-1.6	-0.9	-0.3	0.2	-0.4	-0.4
Had menopause	0.9	1.2	3.6	0.2	1.6	-0.4	-1.7	-0.3	1.9	-0.7	0.5	-0.7
Had other major operations	1.3	1.6	4.5	-1.6	-0.3	-1.8	1.3	0.8	-1.1	0.3	-2.1	-0.5
Forced vital capacity (FVC)	0.6	2.4	4.6	0.2	-1.6	0.5	-2.1	-1.3	-1.7	2.1	0.0	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	16.1	-0.7	-2.5	0.4	-0.9	-3.2	-4.0	0.6	-1.1	1.6
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.5	-0.9	-1.1	-0.5	-0.2	1.2	0.2	1.2	-0.6	0.2
Qualifications: None of the above	0.2	0.5	1.3	-0.9	0.1	-1.1	-1.1	-0.6	0.0	-0.6	-0.0	0.4
Financial difficulties in last 2 years	1.6	2.1	6.0	-1.5	-2.4	-0.5	-0.0	-0.4	-1.5	2.3	-1.5	0.8
Mouth/teeth dental problems	2.1	3.3	7.1	1.9	0.9	2.1	2.2	0.8	1.8	-1.6	1.6	2.7
Heart attack	2.1	2.7	6.2	-2.2	-0.7	-2.5	-0.7	-0.5	-1.1	1.0	-2.2	-2.2
Allergy	0.9	2.1	5.8	1.4	2.3	1.0	-0.2	0.2	0.3	-1.3	2.4	-1.6
Pain all over the body in last month	0.6	0.7	1.7	-1.0	0.4	-1.0	0.1	0.9	0.9	0.1	-1.3	-0.6
Diabetes (self-reported)	0.6	0.9	2.3	-1.5	0.1	-1.4	0.6	0.3	-1.4	0.2	-1.0	-0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.9	0.4	-0.2	0.2	-0.3	1.4	0.6	0.6	0.6	-0.3
Medication: Ramipril	1.0	1.3	3.5	0.6	-0.2	1.6	-1.7	-1.9	-1.4	0.2	0.5	-0.4
Medication: Simvastatin	0.3	0.4	1.2	-0.4	0.2	-0.7	0.1	-1.1	-0.9	-0.8	0.3	-0.3
Fluid intelligence score	0.5	1.1	4.2	-0.9	-0.6	-0.5	-0.5	0.4	-0.4	1.2	-2.0	-1.5
Illnesses of siblings	0.5	0.7	3.6	0.9	0.9	0.4	1.9	0.5	-0.1	-0.5	0.3	0.0
Neuroticism score	1.0	2.0	6.2	-1.2	-1.4	-0.7	-0.3	-2.5	-2.0	0.8	-1.9	0.1
Weight	1.7	8.4	15.8	-3.9	-3.1	-3.5	-0.9	-0.2	-2.7	3.6	-4.0	-1.1
Impedance of arm (right)	4.7	22.0	52.2	5.3	6.2	3.8	2.1	2.3	7.2	-5.9	4.2	0.9
Arm fat percentage (right)	0.1	0.5	1.6	-1.1	0.2	-1.3	0.2	-0.1	-0.3	-0.6	-0.9	0.7
Trunk fat-free mass	3.9	22.4	41.6	-5.9	-4.6	-5.3	-1.9	-0.0	-4.6	6.5	-6.0	-3.8
Hip circumference	1.0	4.1	10.2	-3.2	-1.3	-3.2	-0.2	0.5	-1.5	1.5	-3.0	-0.9
Time employed in main current job	1.7	2.0	3.3	1.4	1.8	1.2	0.6	1.4	1.6	-1.7	1.8	0.4
Alcohol intake versus 10 years previously	0.5	0.8	2.8	-0.1	0.6	-0.9	-1.7	-0.6	1.0	0.1	-0.1	-1.4
Father’s age at death	0.2	0.3	1.5	-0.4	-0.1	-1.2	-0.0	-0.4	0.5	-0.1	-0.6	-0.2
Worrier / anxious feelings	0.5	1.0	3.2	-0.4	0.1	-0.0	1.0	-1.8	-1.6	-0.8	-0.9	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.6	-0.9	-0.6	-0.1	0.5	-0.8	-0.6	0.2	-1.1	1.9
Falls in the last year	0.4	0.6	2.4	-0.8	-0.4	-0.2	-0.7	-0.9	-1.6	0.2	-0.4	0.5
Hair/balding pattern: Pattern 3	0.4	0.6	1.9	0.5	-1.0	0.4	-0.0	1.4	0.4	1.0	1.2	0.3
Number of live births	0.7	1.0	1.5	-0.7	-0.7	-1.1	-1.2	-0.4	-1.1	1.1	-1.2	-1.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	4.7	0.1	-1.9	0.3	-1.7	-1.1	-2.0	2.2	0.1	-1.8
Pulse rate	0.8	1.3	2.9	0.4	0.9	0.4	1.6	1.7	-0.8	-1.7	0.4	1.3
Happiness	1.5	1.8	4.8	2.0	0.4	2.2	-0.6	0.1	1.1	-0.3	2.0	1.1
Noisy workplace	0.5	0.6	1.8	-0.4	-1.3	-0.1	-0.9	0.2	-0.9	1.1	-0.6	0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.4	-0.8	-0.1	-0.7	0.2	0.2	0.3	0.9	-1.0	-1.6
Serious illness, injury or assault of a close relative in last 2 years	3.8	4.3	7.4	-2.0	-2.4	-1.0	-2.0	-2.7	-2.7	2.5	-1.7	-0.5
Mouth/teeth dental problems: Dentures	1.8	3.0	6.9	-2.3	-0.2	-2.6	-1.5	-0.7	-0.5	1.0	-2.5	-2.3
Asthma	0.7	1.3	3.8	-1.3	-1.5	-1.0	0.8	0.2	-0.1	1.2	-1.9	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	4.0	0.1	2.0	0.1	1.3	0.3	0.2	-1.5	0.3	-0.2
Medication: Cholesterol lowering	1.0	1.5	4.0	0.5	-0.1	0.3	0.9	-1.4	-2.0	-1.4	1.5	1.4
Depression (self-reported)	0.6	0.7	2.3	-0.2	-0.9	0.7	-0.9	-0.9	-0.8	1.5	-0.0	0.3
Medication: Lansoprazole	0.4	0.4	1.0	-0.4	0.5	-0.6	-0.8	0.3	-0.9	-0.9	0.1	-1.0
Prospective memory result	0.6	0.8	2.3	0.9	-1.1	1.1	0.3	-0.2	-1.0	0.3	0.6	1.5
Lung cancer (father)	0.9	1.1	5.9	0.2	-1.3	0.3	-0.6	-0.9	-2.4	0.0	0.6	0.8
Illnesses of mother	0.2	0.3	1.0	-0.3	0.2	0.1	0.1	0.5	-0.2	-0.3	-1.0	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	4.1	-0.7	-1.6	-0.7	-1.4	-1.2	-1.5	2.0	-0.4	-1.9
Pulse wave Arterial Stiffness index	1.6	1.9	4.7	0.4	2.0	-0.5	2.2	1.9	1.2	-1.6	0.7	0.2
Impedance of arm (left)	4.0	18.7	47.0	5.0	5.5	3.8	1.8	1.9	6.9	-5.2	4.0	0.9
Arm fat mass (right)	0.8	3.2	6.8	-2.6	-1.8	-2.4	-0.4	-0.3	-2.0	1.7	-2.5	-0.1
Trunk predicted mass	3.9	22.1	41.0	-5.9	-4.6	-5.3	-2.0	0.0	-4.5	6.4	-6.0	-3.8
Standing height	0.8	8.0	21.5	-2.6	-2.1	-2.7	-1.2	0.9	0.0	4.6	-4.1	-3.7
Length of working week for main job	1.4	1.5	4.9	-1.5	-0.8	-1.6	-1.0	-0.1	-0.2	0.8	-2.2	-1.3
Exposure to tobacco smoke at home	0.7	0.7	1.8	-1.1	-0.7	-0.6	-0.4	-0.9	-1.3	1.0	-0.9	-0.1
Breastfed as a baby	0.5	0.6	1.4	0.7	-0.2	0.3	-1.0	1.0	1.1	0.2	1.2	-0.4
Tense / ‘highly strung’	0.2	0.4	1.1	0.8	0.7	0.8	0.2	-1.0	-0.3	-0.4	0.5	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	4.0	-1.3	-1.3	-0.6	-1.4	-2.0	-0.8	1.2	-1.4	1.0
Hair/balding pattern: Pattern 4	1.2	2.9	7.9	-2.5	-0.4	-2.0	-1.4	-0.5	-1.3	1.2	-2.8	-1.5
Birth weight of first child	4.0	7.2	15.6	-3.3	-1.6	-3.5	-0.8	-1.4	-2.0	2.9	-4.0	-2.8
Peak expiratory flow (PEF)	0.4	0.9	4.3	0.3	-1.2	0.7	0.5	0.5	-2.1	1.0	0.4	-0.2
Pulse wave reflection index	0.7	0.9	2.0	0.4	1.4	-0.4	1.2	1.3	0.6	0.1	0.4	-1.4
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.6	-0.8	-0.7	0.1	-0.5	-0.2	-0.7	0.4	-0.2	-0.1
Loud music exposure frequency	2.0	2.2	5.6	-0.9	-1.7	-0.9	-2.4	0.1	-1.1	2.1	-1.2	-1.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.5	0.3	-0.5	0.7	0.6	0.2	-0.3	0.2	0.1	-0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.9	0.4	0.4	0.2	-0.8	-0.9	0.2	-1.0	0.4	0.8
Blood clot in the leg (DVT)	1.0	1.3	2.3	-1.2	-0.8	-1.0	-1.5	-0.7	0.8	1.4	-1.4	-1.3
Medication: Paracetamol	0.6	1.1	2.7	-1.1	-1.3	-0.7	0.3	-0.3	-1.6	0.6	-1.0	1.3
Headache pain in last month	1.6	2.7	6.6	-0.6	-2.6	0.5	-1.1	-2.6	-1.7	1.3	0.1	2.0
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.5	-0.6	0.4	-0.5	0.5	1.3	1.3	0.8	-1.6	-1.2
Glaucoma (self-reported)	0.3	0.4	1.8	0.3	-0.2	0.6	-0.3	-1.4	-1.0	-0.2	0.3	0.4
Gout (self-reported)	1.6	2.2	9.6	-0.7	-3.1	-0.1	-1.3	-0.6	-1.8	1.6	-0.9	0.9
Hypothyroidism/myxoedema (self-reported)	3.7	7.3	19.7	-1.9	-4.4	-0.5	-1.7	-2.0	-3.8	4.1	-1.9	0.3
Medication: Amlodipine	1.5	2.1	5.0	1.7	0.3	2.2	-1.3	0.4	1.0	-1.2	1.4	2.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.6	0.1	0.1	0.2	-0.2	-0.2	0.3	0.1	-0.7	-0.3
Birth weight	1.2	2.5	7.0	-1.9	-0.5	-2.6	-1.9	-0.7	-0.4	2.0	-0.5	-1.8
Chronic bronchitis/emphysema (mother)	0.8	0.9	3.7	1.3	0.1	0.8	0.2	-0.6	1.9	-0.6	0.2	1.1
High blood pressure (siblings)	0.3	0.5	1.3	-1.1	-0.9	-0.8	-0.5	-0.4	-0.2	0.0	-0.6	1.0
Forced vital capacity (FVC), Best measure	0.6	2.2	6.9	-0.5	-1.1	-0.6	-1.8	-1.5	-1.1	2.0	-0.5	-2.6
Body fat percentage	0.1	0.3	1.6	-0.4	0.1	-0.5	0.3	0.1	0.3	-0.8	-0.4	1.3
Leg fat percentage (right)	0.2	0.7	3.5	0.2	0.5	0.2	0.7	0.2	0.2	-1.4	0.4	1.9
Arm fat-free mass (right)	4.0	20.3	38.8	-5.7	-4.9	-4.9	-2.0	-0.3	-4.4	6.2	-5.6	-2.8
Exposure to tobacco smoke outside home	0.5	0.6	1.0	-1.0	0.7	-1.0	1.0	-0.9	-0.7	-0.5	-0.7	-0.5
Comparative body size at age 10	1.4	3.8	10.0	-2.2	-2.0	-1.9	-0.8	-0.7	-3.2	2.5	-2.0	-0.6
Number of full brothers	1.1	1.3	5.4	1.2	-0.3	1.3	-2.3	-1.2	-0.0	-0.1	1.2	0.4
Worry too long after embarrassment	0.6	1.0	2.1	-1.1	-1.4	-0.9	-0.2	-1.4	-0.9	1.0	-1.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.8	0.7	-1.0	0.8	0.2	-1.0	0.7	0.3	0.0	1.9
Wheeze or whistling in the chest in last year	0.4	0.7	2.9	-0.9	-0.7	-0.7	1.0	0.2	-0.2	-0.2	-1.7	0.6
Number of children fathered	0.9	1.1	4.0	-0.4	-1.1	-0.3	-2.0	-1.8	-0.6	-0.3	-0.3	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.3	-0.1	-0.2	-0.3	-0.9	0.8	0.4	0.8	-0.2	-1.1
Age at first live birth	3.2	5.7	10.1	3.0	1.7	3.2	1.8	2.1	2.5	-2.1	3.1	1.3
Pulse wave peak to peak time	1.8	2.1	5.6	-0.4	-2.1	0.4	-2.4	-1.9	-1.0	1.8	-0.8	-0.4
Health satisfaction	0.9	1.2	3.9	-1.2	-1.5	-1.0	-0.6	-0.5	-2.0	0.9	-0.9	0.2
Shortness of breath walking on level ground	0.2	0.3	0.9	-0.4	-0.1	-1.0	0.7	0.1	0.1	0.6	0.7	-0.3
Qualifications: College or University degree	0.2	0.5	1.8	1.3	-0.1	0.8	-0.7	0.5	1.0	0.6	0.1	-0.1
Eye problems/disorders: None of the above	0.5	0.5	2.1	-0.4	-0.7	-0.1	-0.3	1.4	-0.5	1.2	-0.1	-0.5
Mouth/teeth dental problems: Loose teeth	0.9	1.0	3.1	-1.3	0.5	-1.8	-1.1	-0.3	-0.0	-0.6	-0.6	-1.5
Emphysema/chronic bronchitis	0.2	0.2	0.8	-0.2	-0.6	0.1	-0.1	-0.9	-0.4	0.2	0.3	0.8
Medication for pain relief, constipation, heartburn	0.5	0.8	4.0	1.1	0.5	0.7	-0.5	0.6	2.0	0.3	0.4	-0.4
Neck or shoulder pain in last month	0.5	0.7	1.7	-1.0	-0.4	-1.3	-0.2	-0.5	-0.5	1.2	-0.2	-1.3
Medication: Blood pressure	0.5	0.9	2.4	1.0	-0.0	0.9	-0.3	-0.6	0.2	-1.1	1.5	1.3
Angina (self-reported)	1.1	1.5	6.0	-0.0	2.0	-0.4	0.3	-0.7	1.1	-2.4	1.2	-0.3
Migraine (self-reported)	1.6	2.0	6.6	2.1	-0.4	2.0	-0.8	-0.7	-0.4	-0.8	2.6	1.1
Medication: Ibuprofen	1.3	1.6	5.6	0.5	1.5	0.3	2.4	1.2	0.4	-1.9	0.8	0.5
Medication: Allopurinol	1.1	1.5	4.6	-0.7	-2.1	-0.4	-0.5	-1.1	-1.6	1.6	-1.2	0.2
Medication: Omeprazole	0.5	0.6	2.1	-0.1	0.4	0.0	-0.5	-1.4	-0.3	-1.1	0.5	1.0
Medication: Seretide 50 evohaler	0.2	0.3	1.0	0.4	0.4	1.0	0.4	0.5	-0.6	0.2	0.1	0.6
Mean time to correctly identify matches	2.2	4.2	7.8	2.0	2.5	1.4	1.5	-0.7	1.7	-2.8	2.8	2.1
Heart disease (mother)	0.3	0.4	2.0	-0.5	-0.6	-0.3	0.0	-0.0	-1.4	0.5	0.4	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	3.0	-0.1	-0.9	0.4	1.4	1.0	-0.6	0.5	0.3	1.7
Whole body fat mass	0.5	1.9	4.4	-2.0	-1.5	-1.9	-0.3	0.0	-1.1	1.2	-2.1	0.3
Leg fat mass (right)	0.5	1.8	4.0	-2.0	-1.4	-1.7	-0.1	0.1	-1.4	1.2	-1.9	0.5
Arm predicted mass (right)	4.2	21.6	42.6	-5.7	-5.3	-4.9	-2.0	-0.4	-4.8	6.5	-5.7	-2.8
Pulse rate, automated reading	0.6	1.8	8.5	-1.7	0.1	-1.0	0.4	1.1	-2.9	-0.1	-1.0	1.1
Alcohol intake frequency.	1.8	4.1	8.2	-2.4	-2.5	-2.2	-2.0	-2.9	-1.0	1.7	-1.9	-0.2
Comparative height size at age 10	1.5	8.1	17.2	-2.9	-2.1	-3.6	-1.6	0.2	-1.4	4.1	-2.9	-4.2
Number of full sisters	0.8	0.9	2.2	-1.2	-0.4	-0.9	-0.6	-1.0	-0.2	1.5	-0.8	-1.2
Suffer from ‘nerves’	1.9	3.0	8.2	-0.6	-2.2	0.2	-2.4	-2.9	-2.5	1.4	-0.4	0.2
Overall health rating	0.3	0.6	1.5	-0.8	-0.7	-0.8	0.2	-1.0	-1.1	0.0	-0.3	1.2
Chest pain or discomfort	0.2	0.3	1.0	-0.7	-0.2	-0.1	-0.3	-0.5	-1.0	0.4	-0.7	-0.1
Had major operations	2.4	2.8	6.9	-2.6	-0.6	-2.3	-1.2	0.2	-0.4	1.4	-2.2	-2.0
Age at last live birth	4.2	6.1	13.6	3.1	1.6	3.7	2.4	1.5	1.1	-2.0	3.4	2.2
Family relationship satisfaction	0.8	1.0	2.8	1.6	0.8	0.8	0.7	0.4	1.1	-0.9	1.7	0.3
Leg pain on walking	0.5	0.6	2.4	0.2	0.2	0.4	1.5	0.7	-1.1	-0.8	0.2	1.0
Qualifications: NVQ or HND or HNC or equivalent	4.0	4.8	18.3	-1.9	-2.9	-0.6	-0.3	-1.1	-4.3	2.7	-1.9	-0.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.1	1.2	0.6	1.5	-0.2	0.4	1.1	-0.4	0.6	1.1
Illness, injury, bereavement, stress in last 2 years	4.3	5.2	10.2	2.6	3.2	1.8	1.3	1.4	3.0	-3.1	2.1	0.1
Medication: Aspirin	0.4	0.5	2.5	0.7	-0.2	0.6	0.8	-0.2	-0.6	-0.3	1.6	0.1
Supplements: Vitamin C	1.0	1.2	5.9	0.3	0.9	-0.2	2.4	1.8	0.9	-0.2	0.2	-0.0
Knee pain experienced in last month	1.0	1.5	3.7	-1.4	-1.1	-1.0	0.9	-1.0	-1.9	-0.3	-1.1	1.6
Hypertension (Self-reported)	0.9	2.6	6.8	1.7	1.4	2.0	0.8	-0.0	0.9	-2.1	1.5	2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.4	0.2	0.9	0.1	-1.8	-1.6	-0.4	-0.7	0.4	-0.6
Illnesses of father: Heart disease	0.9	1.3	4.3	-0.9	-0.6	-1.4	-0.5	1.3	-0.5	1.0	-1.0	-2.1
Illnesses of siblings: Diabetes	0.7	0.8	3.1	0.2	0.9	0.4	-0.7	1.2	1.0	0.1	1.8	-0.5
Smoking status: Previous	0.3	0.5	1.0	0.4	-0.0	0.3	-1.0	0.9	0.6	0.6	0.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	5.8	-1.6	-1.4	-1.6	0.5	0.7	0.1	2.4	-1.8	-0.5
Whole body fat-free mass	3.8	21.6	39.4	-5.9	-4.6	-5.3	-2.0	-0.0	-4.5	6.3	-6.0	-3.5
Leg fat-free mass (right)	3.5	18.7	33.9	-5.5	-4.5	-4.8	-2.0	-0.4	-4.1	5.8	-5.7	-2.7
Arm fat percentage (left)	0.1	0.5	1.4	-1.1	-0.2	-1.2	-0.1	-0.3	-0.5	-0.2	-1.0	0.8
Average weekly red wine intake	2.4	3.5	8.5	0.8	2.9	0.3	2.2	0.9	2.8	-2.9	0.6	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.6	-0.3	-0.4	-0.6	-0.8	0.1	0.7	1.2	-0.4	-0.5
Mood swings	0.8	1.5	4.7	-1.2	-0.5	-0.7	-0.5	-1.8	-2.2	0.4	-1.6	-0.2
Loneliness, isolation	3.1	4.2	8.2	-2.7	-2.0	-2.2	-0.9	-1.2	-2.9	2.1	-2.4	-1.1
Long-standing illness, disability or infirmity	0.4	0.7	1.7	-1.0	-0.1	-1.1	0.1	-0.7	-0.8	0.6	-1.3	-0.8
Ever had bowel cancer screening	1.1	1.3	4.9	0.1	-2.2	0.3	-1.0	-1.0	-0.4	0.9	-0.2	1.8
Diabetes diagnosed by doctor	0.7	1.1	2.6	-1.5	-0.1	-1.4	1.0	0.6	-1.6	0.4	-1.0	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.7	0.7	0.4	1.3	-0.1	0.2	1.0	-0.5	0.5	1.1
Friendships satisfaction	0.3	0.4	1.0	-0.5	-0.0	-0.9	-1.0	-0.6	0.9	-0.1	-0.2	-0.7
Qualifications: nursing, teaching	0.3	0.5	0.8	0.9	0.3	0.8	0.9	0.6	0.5	0.4	0.8	-0.5
Commuting to job workplace: Walk	0.7	0.7	1.8	-0.9	-0.5	-0.8	-0.4	-0.9	-0.1	1.2	-1.3	-0.7
Eye problems/disorders: Cataract	0.3	0.3	1.6	-0.2	0.2	-0.1	-0.5	-1.3	-0.8	-0.2	-0.4	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	7.6	-1.4	-0.8	-1.1	-1.6	-0.5	-2.8	1.6	-0.4	-2.1
Medication for cholesterol	0.9	1.4	2.9	-1.1	-1.7	-1.3	-0.0	-0.9	-1.6	1.7	-0.5	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	5.0	-2.1	-0.9	-1.4	-1.0	-1.5	-1.4	0.9	-2.2	-0.7
Back pain experienced in last month	1.8	2.7	5.5	-2.4	-1.7	-2.1	-0.5	-1.3	-1.8	1.2	-2.2	0.0
Mineral and other dietary supplements	1.1	1.5	4.1	1.9	-0.2	2.0	-0.3	-0.7	-0.1	0.1	2.0	1.0
Breast cancer (self-reported)	0.7	0.9	2.3	0.5	-1.5	0.6	-0.6	0.1	-1.5	1.1	1.0	0.7
Asthma (self-reported)	0.9	1.8	5.4	-1.6	-1.8	-1.3	1.0	0.1	-0.3	1.3	-2.3	1.0
Osteoporosis (self-reported)	0.8	1.0	3.8	-0.5	-1.3	-0.0	-1.3	-1.9	-0.4	1.1	-0.6	-0.2
Osteoarthritis (self-reported)	0.3	0.4	1.1	-0.6	0.4	-0.9	0.2	0.9	-0.0	0.5	-1.1	-0.7
Medication: Aspirin	0.4	0.5	2.3	0.6	0.0	0.6	0.8	0.5	-0.3	-0.5	1.5	-0.3
Medication: Gliclazide	0.6	0.7	2.3	-0.6	0.6	-0.8	1.5	1.1	0.4	-0.7	-0.7	-0.1
Illnesses of father: None of the above (group 1)	0.5	0.6	2.5	0.8	-0.0	1.6	-0.5	-1.0	-0.5	-0.0	0.8	0.8
Smoking status: Current	0.2	0.4	1.2	0.6	0.3	0.2	0.3	-1.1	0.6	-1.0	0.6	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.0	11.4	-0.7	-2.0	-0.7	-2.9	-1.9	-3.4	2.0	0.2	-2.1
Whole body water mass	3.9	22.0	39.8	-6.0	-4.5	-5.4	-2.1	-0.1	-4.5	6.3	-6.0	-3.5
Leg predicted mass (right)	3.6	19.0	34.7	-5.5	-4.5	-4.9	-2.1	-0.4	-4.1	5.9	-5.7	-2.8
Arm fat mass (left)	0.9	3.7	7.9	-2.8	-1.8	-2.6	-0.7	-0.2	-2.1	1.8	-2.7	-0.4
Number of self-reported non-cancer illnesses	0.2	0.3	2.0	-0.4	-0.2	0.0	-0.2	-0.4	-0.2	-0.3	-0.6	1.4
Average weekly champagne plus white wine intake	0.9	1.2	3.2	-0.8	0.8	-1.5	-0.9	-0.9	0.5	-0.1	-1.4	-1.8
Miserableness	0.5	0.9	3.5	-1.2	-0.1	-0.8	0.9	-0.1	-0.9	0.8	-1.9	-0.3
Guilty feelings	0.3	0.5	3.3	-0.1	-0.7	-0.1	-0.5	-1.8	-0.6	0.1	0.2	0.1
Wears glasses or contact lenses	0.1	0.1	0.7	0.1	-0.1	-0.0	-0.2	-0.8	-0.3	-0.0	0.6	0.3
Ever taken oral contraceptive pill	0.6	0.7	3.5	-0.3	0.7	-0.8	-1.1	-0.2	0.1	-0.6	-0.4	-1.9
Hearing aid user	0.9	1.1	2.3	-1.5	1.1	-1.4	-0.8	-0.6	-0.6	-0.2	-1.1	-1.2
Mother’s age at death	0.1	0.1	0.5	0.0	-0.7	0.2	0.0	-0.2	-0.5	-0.0	-0.2	0.4
Financial situation satisfaction	0.4	0.5	1.5	0.2	-1.1	0.5	-0.7	-0.2	-0.2	1.2	0.8	0.7
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.5	0.3	-0.4	-0.1	-1.0	-0.3	-1.6	0.6	0.3	-0.8
Commuting to job workplace: Public transport	1.2	1.4	3.1	-1.1	-1.8	-0.7	-1.3	-0.8	-1.6	1.3	-1.0	-0.6
Eye problems/disorders: Glaucoma	0.3	0.3	1.7	-0.5	-0.1	-0.1	-0.4	-1.3	-0.4	0.2	-0.8	0.2
Medication: Blood pressure	0.4	0.7	1.7	0.6	1.2	1.3	0.6	0.5	0.3	-1.2	-0.1	0.9
Pain type(s) experienced in last month: Hip pain	0.9	1.2	2.9	-1.4	-1.3	-1.7	1.2	-0.4	-0.6	0.4	-0.9	0.9
Supplements: Fish oil (including cod liver oil)	1.6	2.1	6.9	-2.6	0.1	-2.4	0.3	-0.2	-0.5	-0.2	-2.3	-0.9
High cholesterol (Self-reported)	0.5	0.9	4.4	0.3	-0.7	0.7	-0.5	0.2	-2.1	-0.8	0.8	1.2
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.3	0.7	0.0	0.1	-0.1	0.6	-0.7	-0.9	-0.4
Medication: Paracetamol	0.3	0.5	1.4	-0.5	-0.9	-0.3	1.0	0.4	-0.6	-0.2	-0.6	1.2
Medication: Lisinopril	1.1	1.5	3.5	1.8	0.8	1.3	1.1	-0.1	0.1	-1.9	1.6	0.7
Medication: Atorvastatin	1.8	2.2	10.6	-0.0	-2.3	0.5	-0.7	-0.9	-3.3	0.7	0.3	1.5
Illnesses of father: High blood pressure	0.9	1.1	2.6	-1.0	-0.2	-0.7	0.4	-1.4	1.6	-0.2	-1.6	1.2
Alcohol drinker status: Never	0.3	0.4	1.3	-0.1	0.1	-0.0	1.2	0.2	0.6	-1.0	-0.5	0.9
Ever smoked	0.3	0.6	2.2	0.4	-0.1	0.1	-1.0	0.5	0.3	0.5	1.5	-1.2
Basal metabolic rate	3.4	19.0	33.3	-5.6	-4.4	-5.0	-1.9	-0.2	-4.2	5.8	-5.7	-2.9
Leg fat percentage (left)	0.2	0.6	4.4	0.0	-0.3	0.1	0.5	-0.2	-0.3	-0.9	0.3	2.1
Arm fat-free mass (left)	3.8	19.2	34.1	-5.6	-4.5	-5.0	-2.0	-0.2	-4.5	5.8	-5.4	-2.9
Number of operations (self-reported)	3.4	5.1	14.0	-3.1	-1.0	-2.8	-2.2	-0.6	-1.3	2.0	-3.7	-1.5
Average weekly beer plus cider intake	0.4	0.6	2.6	-0.2	0.1	0.4	0.5	1.4	-1.6	-0.3	0.2	0.6
Irritability	0.3	0.4	1.3	0.4	-0.2	0.9	0.1	-1.1	-1.0	0.6	-0.1	-0.3
Risk taking	0.7	1.1	3.8	0.9	0.3	1.1	-1.2	-1.2	1.0	0.3	1.9	0.2
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.8	-0.1	1.7	-0.8	-0.2	-0.8	0.6	-1.4	0.1	-1.2
Fractured/broken bones in last 5 years	0.1	0.2	0.9	0.4	0.2	0.3	0.4	0.9	0.4	0.3	0.1	-0.1
Age started oral contraceptive pill	1.7	2.1	6.9	-1.8	-1.3	-2.6	-0.6	0.4	-0.9	0.9	-1.6	-1.5
Diastolic blood pressure, automated reading	1.8	5.5	16.0	1.0	2.4	1.3	4.0	2.4	1.9	-2.6	0.9	2.8
Ever depressed for a whole week	1.1	1.3	3.0	-1.7	-1.1	-1.1	-0.7	0.3	-0.5	1.7	-1.4	-1.0
Unable to work because of sickness or disability	0.6	0.8	2.3	-1.5	0.9	-1.0	0.6	0.9	0.3	-0.9	-0.9	0.2
Commuting to job workplace: Cycle	0.9	1.1	3.6	-0.3	-1.2	0.4	-1.9	-1.1	-0.7	1.5	-0.9	-0.5
Myopia	0.6	0.9	2.3	0.2	-0.1	0.2	1.5	1.1	0.1	-0.7	1.3	1.5
Vascular/heart problems diagnosed by doctor	1.0	2.6	5.1	-1.7	-1.5	-2.0	-0.4	-0.1	-0.9	2.1	-1.9	-2.3
Cholesterol lowering medication	0.6	0.8	2.2	-0.6	-1.3	-0.5	-1.4	-0.3	-1.5	0.9	-0.3	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.6	-0.2	0.9	-0.1	-0.9	-1.1	-0.0	-1.6	-0.1	0.3
Pain experienced in last month	0.7	1.2	2.3	1.5	1.5	1.3	-0.5	0.1	0.4	-1.0	1.3	-1.2
Supplements: Calcium	0.4	0.5	1.0	0.1	-0.8	-0.3	-0.9	0.4	1.0	0.3	1.0	-0.8
Basal cell carcinoma (self-reported)	2.5	2.9	7.0	-2.6	-1.4	-2.6	-1.7	-0.4	-1.8	0.9	-1.9	-0.3
Heart attack/myocardial infarction (self-reported)	1.9	2.4	5.3	-2.1	-0.9	-2.3	-0.4	-0.3	-1.2	1.1	-2.1	-2.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.0	-1.2	-0.8	-0.9	-1.7	-0.5	0.6	1.4	-1.4	-1.4
Heart disease (siblings)	1.9	2.3	4.8	-2.2	-1.6	-1.2	-1.4	-1.4	-1.3	1.4	-2.0	-1.0
Alcohol drinker status: Previous	0.8	0.9	2.3	1.0	-0.5	1.5	0.5	-1.0	0.3	-0.2	1.0	1.4
Pack years of smoking	0.2	0.3	1.4	0.1	0.9	-0.2	-0.2	-0.5	-0.2	-1.2	-0.1	-0.7
Impedance of whole body	4.4	22.1	45.0	5.9	5.2	4.8	2.4	1.8	6.7	-5.6	4.9	2.1
Leg fat mass (left)	0.6	2.3	4.5	-2.1	-1.9	-1.8	-0.3	-0.1	-1.7	1.6	-2.0	0.6
Arm predicted mass (left)	4.0	20.1	34.3	-5.8	-4.7	-5.1	-1.9	-0.4	-4.7	5.9	-5.7	-2.7